path: root/data/GENOTOX_data_and_dictionary.tsv

SUB_NAME	SUB_ECSUBINVENTENTRYREF	SUB_CASNUMBER	SUB_TYPE	QUALIFIER	COM_NAME	COM_ECSUBINVENTENTRYREF	COM_CASNUMBER	IUPACNAME	COMPARAMNAME	MOLECULARFORMULA	SMILESNOTATION	INCHI	COM_TYPE	COM_STRUCTURESHOWN	SMILESNOTATIONSOURCE	INCHI_NOTATIONSOURCE	GENOTOX_ENDPOINT	TESTTYPE	METHOD_TYPE	GUIDELINE_QUALIFIER	GENOTOXGUIDELINEFULLTXT	DEVIATION	ACCEPTABILITY	SPECIES	STRAIN	NUMBER_INDIVIDUALS	SEX	ROUTE	EXP_PERIOD	EXPPERIODUNIT	CONTROL	MET_INDICATOR	RESULTS	MOUSELYMPHTEST	INVIVOTISSUEEXP	DARAuthor	DARTitle	DARYear	OpinionType	OpinionAuthor	OpinionTitle	PUBLICATIONDATE	OpinionPubYear	DOI
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	4.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	14.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	small colonies		RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D6			Not reported			no data	with	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D6			Not reported			no data	without	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Ambiguous	no information		RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Ambiguous	no information		RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	ethyl 1-naphthylacetate		2122-70-5	ethyl 2-naphthalen-1-ylacetate	Not in list	C14H14O2	CCOC(=O)CC1=CC=CC2=CC=CC=C21	InChI=1S/C14H14O2/c1-2-16-14(15)10-12-8-5-7-11-6-3-4-9-13(11)12/h3-9H,2,10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar	5	Male	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	5.0000000000	D	yes	not applicable	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	no information		RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: unspecified	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	6-Benzyladenine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Positive			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Positive			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Positive			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Positive			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Positive			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Positive			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Positive			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	with	Positive			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	no information		RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is a metabolite of the substance	bis(8-hydroxyquinolinium) sulphate			quinolin-8-ol	Not in list	C18H16N2O6S	C1=CC2=C(C(=C1)O)N=CC=C2.C1=CC2=C(C(=C1)O)N=CC=C2.OS(=O)(=O)O	InChI=1S/2C9H7NO.H2O4S/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;1-5(2,3)4/h2*1-6,11H;(H2,1,2,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent no treatment	no data	Positive			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Positive			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	15	Male	intraperitoneal	72.0000000000	h	yes	not applicable	Positive		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	15	Male	intraperitoneal	48.0000000000	h	yes	not applicable	Positive		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	15	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Positive		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	12	Male	intraperitoneal	17.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	12	Male	intraperitoneal	36.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	68.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	44.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar	6	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar	6	Male	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar	6	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	NMRI	7	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is part of a mixture or forumlation	Avermectin B1a	265-610-3	65195-55-3	(2aZ,4Z,5'S,6S,6'R,7S,8Z,11R,13S,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17-oxo-5',6,6',10,11,14,15,17,17a,20,20a,20b-dodecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Abamectin (Avermectin B1a)	C48H72O14	CC[C@H](C)[C@@H]1[C@H](C=C[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)C	InChI=1S/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12-,27-15-,32-14-/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1		Male	Not reported	24.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The Netherlands	Acequinocyl (Revised addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: The Netherlands	Acequinocyl (Revised addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-dodecyl-3-hydroxy-1,4-naphthoquinone			2-dodecyl-3-hydroxy-1,4-naphthoquinone	Not in list	C22H30O3	O=C2c1ccccc1C(=O)C(/O)=C2/CCCCCCCCCCCC	InChI=1/C22H30O3/c1-2-3-4-5-6-7-8-9-10-11-16-19-20(23)17-14-12-13-15-18(17)21(24)22(19)25/h12-15,25H,2-11,16H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent no treatment	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	16.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-proficient			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-proficient			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Inconclusive			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Inconclusive			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Inconclusive			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Inconclusive			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Inconclusive			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Inconclusive			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Inconclusive			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Inconclusive			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Inconclusive			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Inconclusive			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Inconclusive			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Inconclusive			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Inconclusive			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Inconclusive			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Inconclusive			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Inconclusive			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Inconclusive			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Inconclusive			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Inconclusive			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Inconclusive			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	4	No data	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	4	No data	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	4	No data	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	4	No data	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	6	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	6	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	6	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	6	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	24	Male/Female	inhalation: unspecified	13.0000000000	week	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	20	Male/Female	inhalation: unspecified	2.0000000000	week	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	20	Male/Female	inhalation: unspecified	2.0000000000	week	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	24	Male/Female	inhalation: unspecified	13.0000000000	week	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	24	Male/Female	inhalation: unspecified	13.0000000000	week	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	24	Male/Female	inhalation: unspecified	2.0000000000	week	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	20	Male/Female	inhalation: unspecified	2.0000000000	week	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	24	Male/Female	inhalation: unspecified	13.0000000000	week	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	20	Male/Female	inhalation: unspecified	2.0000000000	week	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	20	Male/Female	inhalation: unspecified	2.0000000000	week	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	24	Male/Female	inhalation: unspecified	13.0000000000	week	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	24	Male/Female	inhalation: unspecified	2.0000000000	week	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	24	Male/Female	inhalation: unspecified	2.0000000000	week	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	24	Male/Female	inhalation: unspecified	13.0000000000	week	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	24	Male/Female	inhalation: unspecified	13.0000000000	week	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Balb/c	24	Male/Female	inhalation: unspecified	13.0000000000	week	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	10	Male	inhalation: aerosol	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	10	Male	inhalation: aerosol	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	10	Male	inhalation: aerosol	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	10	Male	inhalation: aerosol	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	10	Male	inhalation: aerosol	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	10	Male	inhalation: aerosol	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	10	Male	inhalation: aerosol	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	10	Male	inhalation: aerosol	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	10	Male	inhalation: aerosol	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	10	Male	inhalation: aerosol	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Fischer344	5	Male	inhalation: unspecified	20.0000000000	h	yes	not applicable	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	5	Male	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			yes	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			yes	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	Swiss	11	Male	Not reported			yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	Swiss	11	Male	Not reported			yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	Swiss	11	Male	Not reported			yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Zinc phosphide (Addendum 1)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, historical	without	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, historical	with	Negative			RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Aminopyralid	604-721-7	150114-71-9	single chemical entity	Component is identical to the substance	Aminopyralid	604-721-7	150114-71-9	4-amino-3,6-dichloropyridine-2-carboxylic acid	Aminopyralid	C6H4Cl2N2O2	Clc1c(nc(Cl)cc1N)C(=O)O	InChI=1S/C6H4Cl2N2O2/c7-3-1-2(9)4(8)5(10-3)6(11)12/h1H,(H2,9,10)(H,11,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	6	Male	oral: gavage	24.0000000000	D	yes, historical	not applicable	Negative		no evidence	RMS: The United Kingdom	Aminopyralid (Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aminopyralid.	11Sep2013	2013	doi:10.2903/j.efsa.2013.3352
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	3	Male	oral: gavage	16.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	3	Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Fischer344	4	Female	oral: gavage	4.0000000000	D	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Fischer344	4	Female	oral: gavage	3.0000000000	D	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Fischer344	4	Female	oral: gavage	5.0000000000	D	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Wistar	4	Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Wistar	4	Female	oral: gavage	3.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	Male	oral: gavage	3.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Wistar	4	Female	oral: gavage	3.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Wistar	4	Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	6	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C12H14N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3	InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C12H14N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3	InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C12H14N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3	InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C12H14N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3	InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C12H14N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3	InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C12H14N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3	InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C12H14N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3	InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C12H14N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3	InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C12H14N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3	InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	N-[[(4-hydroxy-6-methoxypyrimidin-2-yl)amino]carbonyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			N-[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C12H14N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(O)cc(OC)n3	InChI=1S/C12H14N10O5S/c1-21-10(6(5-13-21)9-17-20-22(2)18-9)28(25,26)19-12(24)16-11-14-7(23)4-8(15-11)27-3/h4-5H,1-3H3,(H3,14,15,16,19,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C6H9N7O2S	Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O	InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C6H9N7O2S	Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O	InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C6H9N7O2S	Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O	InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C6H9N7O2S	Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O	InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C6H9N7O2S	Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O	InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C6H9N7O2S	Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O	InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C6H9N7O2S	Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O	InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C6H9N7O2S	Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O	InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C6H9N7O2S	Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O	InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide			1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Not in list	C6H9N7O2S	Cn1nc(nn1)c2cnn(C)c2S(N)(=O)=O	InChI=1/C6H9N7O2S/c1-12-6(16(7,14)15)4(3-8-12)5-9-11-13(2)10-5/h3H,1-2H3,(H2,7,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	Yes	Acceptable	Schizosaccharomyces pombe (as organism)				Not reported			yes	with	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	Yes	Acceptable	Schizosaccharomyces pombe (as organism)	Not reported			Not reported			yes	without	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Not reported	4	Male/Female	oral: unspecified	6.0000000000	h	yes	not applicable	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Not reported	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Not reported	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	12	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	12	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Not reported	3	No data	oral: gavage	21.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	12	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	8	Male/Female	oral: gavage	6.0000000000	h	no data	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Not reported	5	Male	oral: feed	3.0000000000	D	yes	not applicable	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	large colonies		RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	small colonies		RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed	2.0000000000	week	yes	not applicable	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male/Female	oral: feed			yes	not applicable	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	no information		RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Ambiguous			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	4-chlorophenol	203-402-6	106-48-9	4-chlorophenol	Not in list	C6H5ClO	C1=CC(=CC=C1O)Cl	InChI=1S/C6H5ClO/c7-5-1-3-6(8)4-2-5/h1-4,8H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is part of a mixture or forumlation	Butyrac 200	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is part of a mixture or forumlation	Butyrac 200	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is part of a mixture or forumlation	Butyrac 200	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is part of a mixture or forumlation	Butyrac 200	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is part of a mixture or forumlation	Butyrac 200	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Positive			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide	244-577-9	21784-53-2	2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one	Not in list	C8H7NO3S	C1C2=CC=CC=C2C(=O)NS1(=O)=O	InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide	244-577-9	21784-53-2	2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one	Not in list	C8H7NO3S	C1C2=CC=CC=C2C(=O)NS1(=O)=O	InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide	244-577-9	21784-53-2	2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one	Not in list	C8H7NO3S	C1C2=CC=CC=C2C(=O)NS1(=O)=O	InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide	244-577-9	21784-53-2	2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one	Not in list	C8H7NO3S	C1C2=CC=CC=C2C(=O)NS1(=O)=O	InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide	244-577-9	21784-53-2	2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one	Not in list	C8H7NO3S	C1C2=CC=CC=C2C(=O)NS1(=O)=O	InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide	244-577-9	21784-53-2	2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one	Not in list	C8H7NO3S	C1C2=CC=CC=C2C(=O)NS1(=O)=O	InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide	244-577-9	21784-53-2	2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one	Not in list	C8H7NO3S	C1C2=CC=CC=C2C(=O)NS1(=O)=O	InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide	244-577-9	21784-53-2	2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one	Not in list	C8H7NO3S	C1C2=CC=CC=C2C(=O)NS1(=O)=O	InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid			2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid	Not in list	C15H16N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC	InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid			2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid	Not in list	C15H16N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC	InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid			2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid	Not in list	C15H16N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC	InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid			2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid	Not in list	C15H16N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC	InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid			2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid	Not in list	C15H16N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC	InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid			2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid	Not in list	C15H16N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC	InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid			2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid	Not in list	C15H16N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC	InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	α-[(4,6-dimethoxypyrimidin-2-ylcarbamoyl)sulfamoyl]-o-toluic acid			2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]sulfamoyl}methyl)benzoic acid	Not in list	C15H16N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)O)OC	InChI=1S/C15H16N4O7S/c1-25-11-7-12(26-2)17-14(16-11)18-15(22)19-27(23,24)8-9-5-3-4-6-10(9)13(20)21/h3-7H,8H2,1-2H3,(H,20,21)(H2,16,17,18,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(sulfamoylmethyl)benzoate	419-010-5	112941-26-1	methyl 2-(sulfamoylmethyl)benzoate	Not in list	C9H11NO4S	COC(=O)C1=CC=CC=C1CS(=O)(=O)N	InChI=1S/C9H11NO4S/c1-14-9(11)8-5-3-2-4-7(8)6-15(10,12)13/h2-5H,6H2,1H3,(H2,10,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide	244-577-9	21784-53-2	2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one	Not in list	C8H7NO3S	C1C2=CC=CC=C2C(=O)NS1(=O)=O	InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide	244-577-9	21784-53-2	2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one	Not in list	C8H7NO3S	C1C2=CC=CC=C2C(=O)NS1(=O)=O	InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(sulfamoylmethyl)benzoate	419-010-5	112941-26-1	methyl 2-(sulfamoylmethyl)benzoate	Not in list	C9H11NO4S	COC(=O)C1=CC=CC=C1CS(=O)(=O)N	InChI=1S/C9H11NO4S/c1-14-9(11)8-5-3-2-4-7(8)6-15(10,12)13/h2-5H,6H2,1H3,(H2,10,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(sulfamoylmethyl)benzoate	419-010-5	112941-26-1	methyl 2-(sulfamoylmethyl)benzoate	Not in list	C9H11NO4S	COC(=O)C1=CC=CC=C1CS(=O)(=O)N	InChI=1S/C9H11NO4S/c1-14-9(11)8-5-3-2-4-7(8)6-15(10,12)13/h2-5H,6H2,1H3,(H2,10,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(sulfamoylmethyl)benzoate	419-010-5	112941-26-1	methyl 2-(sulfamoylmethyl)benzoate	Not in list	C9H11NO4S	COC(=O)C1=CC=CC=C1CS(=O)(=O)N	InChI=1S/C9H11NO4S/c1-14-9(11)8-5-3-2-4-7(8)6-15(10,12)13/h2-5H,6H2,1H3,(H2,10,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(sulfamoylmethyl)benzoate	419-010-5	112941-26-1	methyl 2-(sulfamoylmethyl)benzoate	Not in list	C9H11NO4S	COC(=O)C1=CC=CC=C1CS(=O)(=O)N	InChI=1S/C9H11NO4S/c1-14-9(11)8-5-3-2-4-7(8)6-15(10,12)13/h2-5H,6H2,1H3,(H2,10,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is a metabolite of the substance	1H-2, 3-benzothiazin-4(3H)-one 2,2-dioxide	244-577-9	21784-53-2	2,2-dioxo-1H-2$l^{6},3-benzothiazin-4-one	Not in list	C8H7NO3S	C1C2=CC=CC=C2C(=O)NS1(=O)=O	InChI=1S/C8H7NO3S/c10-8-7-4-2-1-3-6(7)5-13(11,12)9-8/h1-4H,5H2,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	20	Male	intraperitoneal	20.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	20	Male	oral: feed	13.0000000000	week	yes	not applicable	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	House mouse (as animal)	B6C3F1	8	Male	intraperitoneal	6.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	8	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	8	Male/Female	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	8	Male/Female	oral: gavage	16.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Balb/c	5	Male	oral: gavage	28.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	6	Male	oral: gavage	6.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Positive			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	According to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No	Acceptable	Drosophila melanogaster (as animal)	Not reported	200	Male	oral: feed	24.0000000000	h	yes	not applicable	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Sordaria brevicollis (as organism)	Not reported			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI		Male/Female	oral: gavage	6.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	NMRI	50	Male	oral: unspecified			yes	not applicable	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bixafen		581809-46-3	single chemical entity	Component is identical to the substance	Bixafen		581809-46-3	N-(3',4'-dichloro-5-fluorobiphenyl-2-yl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Bixafen	C18H12Cl2F3N3O	FC(F)c3nn(C)cc3C(=O)Nc2ccc(F)cc2c1ccc(Cl)c(Cl)c1	InChI=1S/C18H12Cl2F3N3O/c1-26-8-12(16(25-26)17(22)23)18(27)24-15-5-3-10(21)7-11(15)9-2-4-13(19)14(20)6-9/h2-8,17H,1H3,(H,24,27)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Bixafen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bixafen	05Nov2012	2012	doi:10.2903/j.efsa.2012.2917
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromadiolone	249-205-9	28772-56-7	single chemical entity	Component is identical to the substance	Bromadiolone	249-205-9	28772-56-7	3-[3-[4-(4-Bromophenyl)phenyl]-3-hydroxy-1-phenylpropyl]-4- hydroxychromen-2-one	Bromadiolone	C30H23BrO4	C1=CC=C(C=C1)C(CC(C2=CC=C(C=C2)C3=CC=C(C=C3)Br)O)C4=C(C5=CC=CC=C5OC4=O)O	InChI=1S/C30H23BrO4/c31-23-16-14-20(15-17-23)19-10-12-22(13-11-19)26(32)18-25(21-6-2-1-3-7-21)28-29(33)24-8-4-5-9-27(24)35-30(28)34/h1-17,25-26,32-33H,18H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Sweden	Bromadiolone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromadiolone	13Oct2010	2010	doi:10.2903/j.efsa.2010.1783
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Ambiguous	no information		RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	5	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	5	Male	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	12	Male/Female	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is identical to the substance	Bromuconazole		116255-48-2	2,5-anhydro-4-bromo-1,3,4-trideoxy-2-(2,4-dichlorophenyl)-1-(1H-1,2,4-triazol-1-yl)pentitol	Bromuconazole (sum of diasteroisomers)	C13H12BrCl2N3O	BrC1CC(CN2N=CN=C2)(C3=C(Cl)C=C(Cl)C=C3)OC1	InChI=1S/C13H12BrCl2N3O/c14-9-4-13(20-5-9,6-19-8-17-7-18-19)11-2-1-10(15)3-12(11)16/h1-3,7-9H,4-6H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	12	Male/Female	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	CD-1	15	Male	oral: gavage	5.0000000000	D	yes	not applicable	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is a metabolite of the substance	Ethirimol	245-949-3		5-butyl-2-(ethylamino)-6-methyl-1H-pyrimidin-4-one	Not in list	C11H19N3O	CCCCC1=C(NC(=NC1=O)NCC)C	InChI=1S/C11H19N3O/c1-4-6-7-9-8(3)13-11(12-5-2)14-10(9)15/h4-7H2,1-3H3,(H2,12,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	CD-1	15	Male	oral: gavage	5.0000000000	D	yes	not applicable	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: unspecified	12.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: unspecified	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is identical to the substance	Buprofezin		69327-76-0	2-(tert-butylimino)-5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinan-4-one	Buprofezin	C16H23N3OS	O=C1N(C(C)C)C(SCN1C2=CC=CC=C2)=NC(C)(C)C	InChI=1S/C16H23N3OS/c1-12(2)19-14(17-16(3,4)5)21-11-18(15(19)20)13-9-7-6-8-10-13/h6-10,12H,11H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Finland	Buprofezin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Inconclusive			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Inconclusive			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	3T3			Not reported			yes	with	Positive			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	3T3			Not reported			yes	without	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Cadusafos	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cadusafos (Addendum 3)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cadusafos (Addendum 3)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cadusafos (Addendum 3)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cadusafos (Addendum 3)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cadusafos (Addendum 3)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cadusafos (Addendum 3)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cadusafos (Addendum 3)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cadusafos (Addendum 3)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cadusafos (Addendum 3)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Cadusafos		95465-99-9	single chemical entity	Component is identical to the substance	Cadusafos		95465-99-9	2-[Butan-2-ylsulfanyl(ethoxy)phosphoryl]sulfanylbutane	Cadusafos	C10H23O2PS2	CCC(C)SP(=O)(OCC)SC(C)CC	InChI=1S/C10H23O2PS2/c1-6-9(4)14-13(11,12-8-3)15-10(5)7-2/h9-10H,6-8H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cadusafos (Addendum 3)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cadusafos	20May2009	2009	doi:10.2903/j.efsa.2009.262r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Positive			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1536			Not reported			yes	with	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Positive			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1536			Not reported			yes	without	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes	no data	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	no information		RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	gene mutation	mouse spot test	in vivo	According to	OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test)	No	Acceptable	House mouse (as animal)	C57BL		Female	oral: feed	4.0000000000	D	yes	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	6	Male	oral: gavage	5.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Not reported	5	Male	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Not reported		No data	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	5	No data	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	54.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	30.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	CD-1		Male	oral: gavage	4.0000000000	h	no data	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	C57BL	5	No data	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	CD-1		Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	C57BL		Male	oral: feed	24.0000000000	h	yes	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	C57BL		No data	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Folpet	205-087-0	133-07-3	single chemical entity	Component is part of a group but not included in the group assessment	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other		chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	CD-1		Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is part of a group but not included in the group assessment	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other		chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	CD-1		Male	oral: gavage	4.0000000000	h	no data	not applicable	Negative			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is part of a group but not included in the group assessment	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other		chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	CD-1		No data	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is part of a group but not included in the group assessment	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other		chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	C57BL		Male	oral: feed	24.0000000000	h	yes	not applicable	Negative			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is part of a group but not included in the group assessment	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other		chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	C57BL	5	No data	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is part of a group but not included in the group assessment	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other		chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	C57BL		No data	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	4.0000000000	h	yes	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	12.0000000000	h	yes	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar	5	Male	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	Not reported	15	Male	oral: unspecified	5.0000000000	D	yes	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	Not reported	15	Male	intraperitoneal			yes	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	Rat (as animal)	Not reported	15	Male	oral: gavage			yes	not applicable	Ambiguous			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	Rat (as animal)	Not reported	15	Male	intraperitoneal	5.0000000000	D	yes	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	Not reported	15	Male	oral: gavage			yes	not applicable	Ambiguous			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male	intraperitoneal			yes	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
Captan	205-087-0	133-06-2	single chemical entity	Component is identical to the substance	Captan	205-087-0	133-06-2	2-[(trichloromethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione	Captan	C9H8Cl3NO2S	ClC(Cl)(Cl)SN1C(=O)C2CC=CCC2C1=O	InChI=1/C9H8Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-2,5-6H,3-4H2	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male	oral: gavage			yes	not applicable	Negative			RMS: Italy	Captan	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance captan	22Oct2009	2009	doi:10.2903/j.efsa.2009.296r
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Positive	small colonies		RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Positive	large colonies		RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
1-Methylcyclopropene		3100-04-7	single chemical entity	Component is identical to the substance	1-Methylcyclopropene		3100-04-7	1-methylcyclopropene	1-methylcyclopropene	C4H6	CC1=CC1	InChI=1S/C4H6/c1-4-2-3-4/h2H,3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	1-Methylcyclopropene	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance 1-methylcyclopropene	12May2005	2005	doi:10.2903/j.efsa.2005.30r
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	7	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Geraniol	269-750-6	106-24-1	single chemical entity	Component is part of a group assessment	Geranyl acetate	203-341-5	105-87-3	[(2E)-3,7-dimethylocta-2,6-dienyl] acetate	Not in list	C12H20O2	CC(=CCCC(=CCOC(=O)C)C)C	InChI=1S/C12H20O2/c1-10(2)6-5-7-11(3)8-9-14-12(4)13/h6,8H,5,7,9H2,1-4H3/b11-8+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	6	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
2-(1-Naphthyl)acetamide	201-704-2	86-86-2	single chemical entity	Component is identical to the substance	2-(1-Naphthyl)acetamide	201-704-2	86-86-2	2-naphthalen-1-ylacetamide	Not in list	C12H11NO	NC(=O)Cc1cccc2ccccc12	InChI=1/C12H11NO/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H2,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphthaleneacetamide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2-(1-naphthyl)acetamide (notified as 1-naphthylacetamide)	23Feb2011	2011	doi:10.2903/j.efsa.2011.2020
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is a metabolite of the substance	sodium 1-naphthylacetate		61-31-4	sodium;2-naphthalen-1-ylacetate	Not in list	C12H9NaO2	C1=CC=C2C(=C1)C=CC=C2CC(=O)[O-].[Na+]	InChI=1S/C12H10O2.Na/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10;/h1-7H,8H2,(H,13,14);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			no data	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			no data	without	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			no data	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
1-Naphthylacetic acid	201-705-8	86-87-3	single chemical entity	Component is identical to the substance	1-Naphthylacetic acid	201-705-8	86-87-3	1-2-naphthalen-1-ylacetic acid	1-naphthylacetic acid	C12H10O2	OC(=O)Cc1cccc2ccccc12	InChI=1/C12H10O2/c13-12(14)8-10-6-3-5-9-4-1-2-7-11(9)10/h1-7H,8H2,(H,13,14)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			no data	with	Negative			RMS: France	Naphtaleneacetic acid	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1-naphthylacetic acid	23Feb2011	2011	doi:10.2903/j.efsa.2011.2019
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1	4	Male	intraperitoneal	23.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
8-Hydroxyquinoline	205-711-1	148-24-3	single chemical entity	Component is identical to the substance	8-Hydroxyquinoline	205-711-1	148-24-3	Quinolin-8-ol	Not in list	C9H7NO	C1=CC2=C(C(=C1)O)N=CC=C2	InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1	4	Male	intraperitoneal	42.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	8-Hydroxyquinoline (Variant: 8-Hydroxyquinoline neutral sulphate)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 8-hydroxyquinoline	28Jan2011	2011	doi:10.2903/j.efsa.2011.1964
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	mixture or formulation	Component is identical to the substance	Abamectin		71751-41-2	(9Z,13Z,15Z)-6'-(butan-2-yl)-19,21b-dihydroxy-5',10,12,20-tetramethyl-1-oxo-3,4,5',6',8,11,12,18,18a,19,21a,21b-dodecahydro-1H,7H,16H-spiro[3,7-methanopyrano[3,4,5-pq][2,6]benzodioxacyclooctadecine-5,2'-pyran]-11-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methylhexopyranosyl)-3-O-methylhexopyranoside	Abamectin (sum of Avermectin B1a, AvermectinB1b and delta-8,9 isomer of Avermectin B1a)	C49H74O14	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COCC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C	InChI=1S/C49H74O14/c1-11-26(2)45-29(5)17-18-48(63-45)23-35-20-34(62-48)16-15-28(4)44(60-41-22-39(55-10)46(32(8)58-41)61-40-21-38(54-9)43(51)31(7)57-40)27(3)13-12-14-33-24-56-25-37-42(50)30(6)19-36(47(52)59-35)49(33,37)53/h12-15,17-19,26-27,29,31-32,34-46,50-51,53H,11,16,20-25H2,1-10H3/b13-12-,28-15-,33-14-	organic	representative compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Abamectin		71751-41-2	single chemical entity	Component is a metabolite of the substance	[8,9-Z]-isomer of avermectin B1a			{(2aZ,4Z,5'S,6R,6'R,7Z,10R,12S,14S,16aR,19R,19aR,19bS)-6'-[(2S)-butan-2-yl]-19,19b-dihydroxy-5',6,7,18-tetramethyl-16-oxo-5',6,6',9,10,13,14,16,16a,19,19a,19b-dodecahydro-2H-spiro[10,14-methanofuro[4,3,2-op][2,6]benzodioxacycloheptadecine-12,2'-pyran]-6-yl}methyl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside	Avermectin B1a, delta-8,9 isomer	C47H70O14	CO[C@H]1C[C@@H](O[C@@H](C)[C@@H]1O)O[C@@H]2[C@@H](OC)C[C@@H](O[C@H]2C)OC[C@]5(C)C=CC=C6CO[C@@H]7[C@H](O)C(C)=C[C@@H](C(=O)O[C@H]3C[C@H](O[C@]4(C3)C=C[C@H](C)[C@H](O4)[C@@H](C)CC)CC=C5C)[C@]67O	InChI=1S/C48H72O14/c1-11-26(2)42-27(3)16-18-47(62-42)23-34-20-33(61-47)15-14-29(5)46(8,17-12-13-32-24-55-44-40(49)28(4)19-35(45(51)59-34)48(32,44)52)25-56-38-22-37(54-10)43(31(7)58-38)60-39-21-36(53-9)41(50)30(6)57-39/h12-14,16-19,26-27,30-31,33-44,49-50,52H,11,15,20-25H2,1-10H3/b17-12-,29-14-,32-13-/t26-,27-,30-,31-,33+,34-,35-,36-,37-,38+,39-,40+,41-,42+,43-,44+,46-,47+,48+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Abamectin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance abamectin. Please note the current definition for the ISO name is exactly an 80% to 20% mixture of avermectins B1a and B1b. However the material discussed in thi	29Jul2008	2008	doi:10.2903/j.efsa.2008.147r
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is identical to the substance	Acequinocyl		57960-19-7	3-dodecyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl acetate	Acequinocyl	C24H32O4	CC(=O)OC2=C(CCCCCCCCCCCC)C(=O)c1ccccc1C2=O	InChI=1S/C24H32O4/c1-3-4-5-6-7-8-9-10-11-12-17-21-22(26)19-15-13-14-16-20(19)23(27)24(21)28-18(2)25/h13-16H,3-12,17H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acequinocyl		57960-19-7	single chemical entity	Component is a metabolite of the substance	2-(2-oxotetradecanoyl)benzoic acid			2-(2-oxododecanoyl)benzoic acid	Not in list	C19H26O4	O=C(O)c1ccccc1C(=O)C(=O)CCCCCCCCCC	InChI=1/C19H26O4/c1-2-3-4-5-6-7-8-9-14-17(20)18(21)15-12-10-11-13-16(15)19(22)23/h10-13H,2-9,14H2,1H3,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Acequinocyl (Revised version of September 2007)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acequinocyl.	02May2013	2013	doi:10.2903/j.efsa.2013.3212
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	6-Benzyladenine (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	6-Benzyladenine (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	6-Benzyladenine (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
6-Benzyladenine	214-927-5	1214-39-7	single chemical entity	Component is identical to the substance	6-Benzyladenine	214-927-5	1214-39-7	N-benzyl-7H-purin-6-amine	6-Benzyladenine	C12H11N5	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3	InChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	6-Benzyladenine (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 6-benzyladenine	22Oct2010	2010	doi:10.2903/j.efsa.2010.1716
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	4	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is identical to the substance	Acibenzolar-S-methyl		135158-54-2	Benzo[1,2,3]thiadiazole-7-carbothioic acid S-methyl ester	Acybenzolar-S-methyl	C8H6N2OS2	CSC(=O)C1=C2C(=CC=C1)N=NS2	InChI=1S/C8H6N2OS2/c1-12-8(11)5-3-2-4-6-7(5)13-10-9-6/h2-4H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	4	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: France - CoRMS: Spain	Acibenzolar-S-Methyl (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Positive			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	1,2,3-benzothiadiazole-7-carboxylic acid		35272-27-6	1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O2S	C1=CC(=C2C(=C1)N=NS2)C(=O)O	InChI=1S/C7H4N2O2S/c10-7(11)4-2-1-3-5-6(4)12-9-8-5/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			4-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1ccc(O)c2nnsc12	InChI=1/C7H4N2O3S/c10-4-2-1-3(7(11)12)6-5(4)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Acibenzolar-S-methyl		135158-54-2	single chemical entity	Component is a metabolite of the substance	5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid			5-hydroxy-1,2,3-benzothiadiazole-7-carboxylic acid	Not in list	C7H4N2O3S	O=C(O)c1cc(O)cc2nnsc12	InChI=1/C7H4N2O3S/c10-3-1-4(7(11)12)6-5(2-3)8-9-13-6/h1-2,10H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acibenzolar-s-methyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acibenzolar-S-methyl	12Aug2014	2014	doi:10.2903/j.efsa.2014.3691
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
Aclonifen	277-704-1	74070-46-5	single chemical entity	Component is identical to the substance	Aclonifen	277-704-1	74070-46-5	2-chloro-6-nitro-3-phenoxyaniline	Aclonifen	C12H9ClN2O3	Clc2c(N)c(ccc2Oc1ccccc1)[N+]([O-])=O	InChI=1S/C12H9ClN2O3/c13-11-10(18-8-4-2-1-3-5-8)7-6-9(12(11)14)15(16)17/h1-7H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Aclonifen	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Aclonifen	21Oct2008	2008	doi:10.2903/j.efsa.2008.149r
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Not reported	5	Male/Female	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Not reported	5	Male/Female	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is identical to the substance	Acrinathrin		101007-06-1	[(S)-cyano-(3-phenoxyphenyl)methyl](1R,3S)-3-[(Z)-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Acrinathrin	C26H21F6NO5	CC1([C@H]([C@H]1C(=O)O[C@H](C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)/C=C\C(=O)OC(C(F)(F)F)C(F)(F)F)C	InChI=1S/C26H21F6NO5/c1-24(2)18(11-12-20(34)38-23(25(27,28)29)26(30,31)32)21(24)22(35)37-19(14-33)15-7-6-10-17(13-15)36-16-8-4-3-5-9-16/h3-13,18-19,21,23H,1-2H3/b12-11-/t18-,19+,21-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid			(2Z)-3-(3-{[cyano(3-phenoxyphenyl)methoxy]carbonyl}-2,2-dimethylcyclopropyl)prop-2-enoic acid	Acrinathrin	C23H21NO5	OC(=O)/C=C\C3C(C(=O)OC(C#N)c2cccc(Oc1ccccc1)c2)C3(C)C	InChI=1/C23H21NO5/c1-23(2)18(11-12-20(25)26)21(23)22(27)29-19(14-24)15-7-6-10-17(13-15)28-16-8-4-3-5-9-16/h3-13,18-19,21H,1-2H3,(H,25,26)/b12-11-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Acrinathrin		101007-06-1	single chemical entity	Component is a metabolite of the substance	3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid			3-[(Z)-2-carboxyethenyl]-2,2-dimethylcyclopropanecarboxylic acid	Acrinathrin	C9H12O4	OC(=O)/C=C\C1C(C(=O)O)C1(C)C	InChI=1/C9H12O4/c1-9(2)5(3-4-6(10)11)7(9)8(12)13/h3-5,7H,1-2H3,(H,10,11)(H,12,13)/b4-3-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Acrinathrin (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance acrinathrin.	19Dec2013	2013	doi:10.2903/j.efsa.2013.3469
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is identical to the substance	Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	Aluminum;azanium;disulfate;dodecahydrate	Aluminium ammonium sulphate dodecahydrate	AlH28NO20S2	[NH4+].O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3]	InChI=1S/Al.H3N.2H2O4S.12H2O/c;;2*1-5(2,3)4;;;;;;;;;;;;/h;1H3;2*(H2,1,2,3,4);12*1H2/q+3;;;;;;;;;;;;;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is identical to the substance	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Magnesium phosphide	235-023-7	12057-74-8	Trimagnesium;phosphorus(3-)	Not in list	Mg3P2	[Mg+2].[Mg+2].[Mg+2].[P-3].[P-3]	InChI=1S/3Mg.2P/q3*+2;2*-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is identical to the substance	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium phosphide	244-088-0	20859-73-8	phosphinidyne aluminum	Not in list	AlP	[Al]#P	InChI=1/Al.P/rAlP/c1-2	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Phosphine	232-260-8	7803-51-2	single chemical entity	Component is identical to the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Phosphane	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance phosphane	02Mar2012	2012	doi:10.2903/j.efsa.2012.2595
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Magnesium phosphide	235-023-7	12057-74-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Magnesium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance magnesium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.190r
Zinc phosphide	215-244-5	1314-84-7	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Zinc phosphide	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance zinc phosphide	19Jul2010	2010	doi:10.2903/j.efsa.2010.1671
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Calcium phosphide	215-142-0	1305-99-3	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Calcium phosphide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance calcium phosphide	22Oct2008	2008	doi:10.2903/j.efsa.2008.183r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Aluminium phosphide	244-088-0	20859-73-8	single chemical entity	Component is a metabolite of the substance	Phosphine	232-260-8	7803-51-2	phosphine	Not in list	H3P	P	InChI=1S/H3P/h1H3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Aluminium phosphide (Final Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance aluminium phosphide	15Jan2009	2009	doi:10.2903/j.efsa.2009.182r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is identical to the substance	Amidosulfuron		120923-37-7	1-(4,6-dimethoxypyrimidin-2-yl)-3-[methyl(methylsulfonyl)sulfamoyl]urea	Amidosulfuron	C9H15N5O7S2	O=C(Nc1nc(cc(OC)n1)OC)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1S/C9H15N5O7S2/c1-14(22(4,16)17)23(18,19)13-9(15)12-8-10-6(20-2)5-7(11-8)21-3/h5H,1-4H3,(H2,10,11,12,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea			3-(4-hydroxy-6-methoxypyrimidin-2-yl)-1-(N-methyl-N-methylsulfonylaminosulfonyl)-urea	Not in list	C8H13N5O7S2	O=C(Nc1nc(O)cc(OC)n1)NS(=O)(=O)N(C)S(C)(=O)=O	InChI=1/C8H13N5O7S2/c1-13(21(3,16)17)22(18,19)12-8(15)11-7-9-5(14)4-6(10-7)20-2/h4H,1-3H3,(H3,9,10,11,12,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dihydroxypyrimidine	200-256-5	56-09-7	2-amino-4-hydroxy-1H-pyrimidin-6-one	Not in list	C4H5N3O2	C1=C(N=C(NC1=O)N)O	InChI=1S/C4H5N3O2/c5-4-6-2(8)1-3(9)7-4/h1H,(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Amidosulfuron		120923-37-7	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Amidosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance amidosulfuron	09Nov2008	2008	doi:10.2903/j.efsa.2008.116r
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	20	Male/Female	oral: gavage	30.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	20	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Female	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Female	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Female	oral: gavage	8.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Female	oral: gavage	0.2500000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Female	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Female	oral: gavage	1.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Female	oral: gavage	1.5000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Female	oral: gavage	0.5000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	6	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is identical to the substance	Carbetamide	240-286-6	16118-49-3	1-(ethylamino)-1-oxopropan-2-yl phenylcarbamate	Carbetamide	C12H16N2O3	O=C(NCC)C(OC(NC1=CC=CC=C1)=O)C	InChI=1S/C12H16N2O3/c1-3-13-11(15)9(2)17-12(16)14-10-7-5-4-6-8-10/h4-9H,3H2,1-2H3,(H,13,15)(H,14,16)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	6	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is identical to the substance	Amisulbrom		348635-87-0	3-(3-bromo-6-fluoro-2-methylindol-1-ylsulfonyl)-N,N-dimethyl-1,2,4-triazole-1-sulfonamide	Amisulbrom	C13H13BrFN5O4S2	CC1=C(C2=C(N1S(=O)(=O)C3=NN(C=N3)S(=O)(=O)N(C)C)C=C(C=C2)F)Br	InChI=1S/C13H13BrFN5O4S2/c1-8-12(14)10-5-4-9(15)6-11(10)20(8)25(21,22)13-16-7-19(17-13)26(23,24)18(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is a metabolite of the substance	3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole			3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole	Not in list	C11H8BrFN4O2S	O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3	InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is a metabolite of the substance	3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole			3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole	Not in list	C11H8BrFN4O2S	O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3	InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is a metabolite of the substance	3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole			3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole	Not in list	C11H8BrFN4O2S	O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3	InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is a metabolite of the substance	3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole			3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole	Not in list	C11H8BrFN4O2S	O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3	InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is a metabolite of the substance	3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole			3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole	Not in list	C11H8BrFN4O2S	O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3	InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is a metabolite of the substance	3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole			3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole	Not in list	C11H8BrFN4O2S	O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3	InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is a metabolite of the substance	3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole			3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole	Not in list	C11H8BrFN4O2S	O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3	InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is a metabolite of the substance	3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole			3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole	Not in list	C11H8BrFN4O2S	O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3	InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is a metabolite of the substance	3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole			3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole	Not in list	C11H8BrFN4O2S	O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3	InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Amisulbrom		348635-87-0	single chemical entity	Component is a metabolite of the substance	3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole			3-bromo-6-fluoro-2-methyl-1-(1H-1,2,4-triazol-3-ylsulfonyl)-1H-indole	Not in list	C11H8BrFN4O2S	O=S(=O)(n2c1cc(F)ccc1c(Br)c2C)c3ncnn3	InChI=1/C11H8BrFN4O2S/c1-6-10(12)8-3-2-7(13)4-9(8)17(6)20(18,19)11-14-5-15-16-11/h2-5H,1H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Amisulbrom	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amisulbrom	07Apr2014	2014	doi:10.2903/j.efsa.2014.3237
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	small colonies		RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	small colonies		RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley		Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is identical to the substance	Azoxystrobin		131860-33-8	methyl (2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyacrylate	Azoxystrobin	C22H17N3O5	N#CC1=CC=CC=C1OC2=NC=NC(OC3=CC=CC=C3/C(C(OC)=O)=C\OC)=C2	InChI=1S/C22H17N3O5/c1-27-13-17(22(26)28-2)16-8-4-6-10-19(16)30-21-11-20(24-14-25-21)29-18-9-5-3-7-15(18)12-23/h3-11,13-14H,1-2H3/b17-13+	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley		Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	(2E)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-3-methoxyprop-2-enoic acid			(2Z)-2-(2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}phenyl)-4-oxopent-2-enoic acid	Not in list	C22H15N3O5	CC(=O)\C=C(/C(=O)O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C22H15N3O5/c1-14(26)10-17(22(27)28)16-7-3-5-9-19(16)30-21-11-20(24-13-25-21)29-18-8-4-2-6-15(18)12-23/h2-11,13H,1H3,(H,27,28)/b17-10-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Azoxystrobin	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Ambiguous			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Ambiguous			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	Not reported			Not reported			no data	without	Positive			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Positive			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Positive			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1		No data	Not reported			no data	not applicable	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
L-ascorbic acid	200-066-2	50-81-7	single chemical entity	Component is identical to the substance	L-ascorbic acid	200-066-2	50-81-7	(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one	L-ascorbic acid	C6H8O6	C(C(C1C(=C(C(=O)O1)O)O)O)O	InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	B6C3F1		No data	Not reported			no data	not applicable	Negative			RMS: The Netherlands	L-ascorbic acid	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance L-ascorbic acid	25Apr2013	2013	doi: 10.2903/j.efsa.2013.3197
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Trifolio-M GmbH source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: microorganisms or derived from microorganisms	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Sipcam S.p.A source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Azadirachtin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Germany	Azadirachtin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Germany	Azadirachtin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Azadirachtin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Azadirachtin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Azadirachtin A		11141-17-6	complex product: derived from botanical sources	Component is the active ingredient of the mixture or formulation	Azadirachtin extract (Mitsui AgriScience International S.A/B.V source)			methyl 10,10a-bis(acetyloxy)-3,5-dihydroxy-4-(6a-hydroxy-7a-methyl-3a,6a,7,7a-tetrahydro-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl)-4-methyl-8-{[(2E)-2-methylbut-2-enoyl]oxy}decahydro-1H-naphtho[1,8a-c:4,5-b'c']difuran-5-carboxylate	Not in list	C35H44O16	C24(C(C3C1(C=COC1OC2C3)O)(C)O4)C6(C8C5(C(CC(C7(C5C(C6O)OC7)OC(=O)C)OC(=O)C)OC(/C(=C/C)C)=O)COC8(C(=O)OC)O)C	InChI=1S/C35H44O16/c1-8-15(2)25(39)48-19-12-20(47-16(3)36)33(50-17(4)37)14-45-22-23(33)31(19)13-46-34(42,27(40)43-7)26(31)29(5,24(22)38)35-21-11-18(30(35,6)51-35)32(41)9-10-44-28(32)49-21/h8-10,18-24,26,28,38,41-42H,11-14H2,1-7H3/b15-8+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Azadirachtin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azadirachtin	17Mar2011	2011	doi:10.2903/j.efsa.2011.1858
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3052			Not reported			yes	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			yes	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3052			Not reported			yes	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3076			Not reported			yes	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3076			Not reported			yes	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			yes	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	IN-E6758			phenyl (4,6-dimethoxypyrimidin-2-yl)carbamate	Not in list	C13H13N3O4	O=C(Oc1ccccc1)Nc2nc(cc(OC)n2)OC	InChI=1/C13H13N3O4/c1-18-10-8-11(19-2)15-12(14-10)16-13(17)20-9-6-4-3-5-7-9/h3-8H,1-2H3,(H,14,15,16,17)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	IN-E6758			phenyl (4,6-dimethoxypyrimidin-2-yl)carbamate	Not in list	C13H13N3O4	O=C(Oc1ccccc1)Nc2nc(cc(OC)n2)OC	InChI=1/C13H13N3O4/c1-18-10-8-11(19-2)15-12(14-10)16-13(17)20-9-6-4-3-5-7-9/h3-8H,1-2H3,(H,14,15,16,17)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is a metabolite of the substance	IN-E6758			phenyl (4,6-dimethoxypyrimidin-2-yl)carbamate	Not in list	C13H13N3O4	O=C(Oc1ccccc1)Nc2nc(cc(OC)n2)OC	InChI=1/C13H13N3O4/c1-18-10-8-11(19-2)15-12(14-10)16-13(17)20-9-6-4-3-5-7-9/h3-8H,1-2H3,(H,14,15,16,17)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Azimsulfuron	601-676-5	120162-55-2	single chemical entity	Component is identical to the substance	Azimsulfuron	601-676-5	120162-55-2	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-1-methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide	Azimsulfuron	C13H16N10O5S	Cn1nc(nn1)c2cnn(C)c2S(=O)(=O)NC(=O)Nc3nc(OC)cc(OC)n3	InChI=1S/C13H16N10O5S/c1-22-11(7(6-14-22)10-18-21-23(2)19-10)29(25,26)20-13(24)17-12-15-8(27-3)5-9(16-12)28-4/h5-6H,1-4H3,(H2,15,16,17,20,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Sweden - CoRMS: Slovenia	Azimsulfuron (Corrigendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azimsulfuron	26Mar2010	2010	doi:10.2903/j.efsa.2010.1554
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfluralin	217-465-2	1861-40-1	single chemical entity	Component is identical to the substance	Benfluralin	217-465-2	1861-40-1	N-butyl-N-ethyl-2,6-dinitro-4-(trifluoromethyl)aniline	Benfluralin	C13H16F3N3O4	CCCCN(CC)C1=C(C=C(C=C1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1S/C13H16F3N3O4/c1-3-5-6-17(4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfluralin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benfluralin	28Jul2008	2008	doi:10.2903/j.efsa.2008.127r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	48.0000000000	h	yes, historical	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	24.0000000000	h	yes, historical	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	30	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	30	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bensulfuron-methyl	401-340-6	83055-99-6	single chemical entity	Component is identical to the substance	Bensulfuron-methyl	401-340-6	83055-99-6	Methyl 2-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoylmethyl]benzoate	Bensulfuron-Methyl	C16H18N4O7S	COC1=CC(=NC(=N1)NC(=O)NS(=O)(=O)CC2=CC=CC=C2C(=O)OC)OC	InChI=1S/C16H18N4O7S/c1-25-12-8-13(26-2)18-15(17-12)19-16(22)20-28(23,24)9-10-6-4-5-7-11(10)14(21)27-3/h4-8H,9H2,1-3H3,(H2,17,18,19,20,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	30	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Bensulfuron Methyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bensulfuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.178r
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	ICR	6	Male	oral: gavage	3.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent no treatment	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent no treatment	with	Ambiguous			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Wistar		Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar		Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is part of a group assessment	bentazone sodium	256-735-4	50723-80-3	sodium;2,2-dioxo-3-propan-2-yl-2$l^{6},1,3-benzothiadiazin-1-id-4-one	Not in list	C10H11N2NaO3S	CC(C)N1C(=O)C2=CC=CC=C2[N-]S1(=O)=O.[Na+]	InChI=1S/C10H12N2O3S.Na/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15;/h3-7H,1-2H3,(H,11,13);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	Not reported			yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male/Female	oral: feed			yes	not applicable	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is a metabolite of the substance	8-hydroxy-3-isopropyl-1H-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide	611-967-9	60374-43-8	8-hydroxy-2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O4S	CC(C)N1C(=O)C2=C(C(=CC=C2)O)NS1(=O)=O	InChI=1S/C10H12N2O4S/c1-6(2)12-10(14)7-4-3-5-8(13)9(7)11-17(12,15)16/h3-6,11,13H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Bentazone	246-585-8	25057-89-0	single chemical entity	Component is identical to the substance	Bentazone	246-585-8	25057-89-0	2,2-dioxo-3-propan-2-yl-1H-2$l^{6},1,3-benzothiadiazin-4-one	Not in list	C10H12N2O3S	CC(C)N1C(=O)C2=CC=CC=C2NS1(=O)=O	InChI=1S/C10H12N2O3S/c1-7(2)12-10(13)8-5-3-4-6-9(8)11-16(12,14)15/h3-7,11H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Bentazone (RAR)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Bentazone	20Apr2015	2015	doi: 10.2903/j.efsa.2015.4077
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Beta-Cypermethrin	265-898-0	65731-84-2	single chemical entity	Component is identical to the substance	Beta-Cypermethrin	265-898-0	65731-84-2	A reaction mixture comprising two enantiomeric pairs in ratio ca. 2:3 of (R)-alpha-cyano-3-phenoxybenzyl (1S)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-cis-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate with (R)-alpha-cyano-3-phenoxybenzyl (1S)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate and (S)-alpha-cyano-3-phenoxybenzyl (1R)-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate	Beta-cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Beta-Cypermethrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance beta-cypermethrin	20Jun2014	2014	doi:10.2903/j.efsa.2014.3717
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Bifenox	255-894-7	42576-02-3	single chemical entity	Component is identical to the substance	Bifenox	255-894-7	42576-02-3	methyl 5-(2,4-dichlorophenoxy)-2-nitrobenzoate	Bifenox	C14H9Cl2NO5	[O-][N+](C(C=C2)=C(C=C2OC1=CC=C(Cl)C=C1Cl)C(OC)=O)=O	InChI=1S/C14H9Cl2NO5/c1-21-14(18)10-7-9(3-4-12(10)17(19)20)22-13-5-2-8(15)6-11(13)16/h2-7H,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Belgium	Bifenox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance bifenox	14Feb2008	2008	doi:10.2903/j.efsa.2008.119r
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl	2000	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is identical to the substance	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-DL-alaninate			3-[(2,6-dimethylphenyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-oxopropanoic acid	Not in list	C15H19NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1S/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	small colonies		RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	large colonies		RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	small colonies		RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl	275-728-7	71626-11-4	single chemical entity	Component is a metabolite of the substance	N-(malonyl)-N-(2,6-xylyl)-DL-alanine			N-(carboxyacetyl)-N-(2,6-dimethylphenyl)alanine	Not in list	C14H17NO5	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H17NO5/c1-8-5-4-6-9(2)13(8)15(10(3)14(19)20)11(16)7-12(17)18/h4-6,10H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	large colonies		RMS: Portugal	Benalaxyl (Addendum 8)	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluoro-2-hydroxybenzothiazole			6-fluoro-1,3-benzothiazol-2-ol	Not in list	C7H4FNOS	Fc1ccc2nc(O)sc2c1	InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluoro-2-hydroxybenzothiazole			6-fluoro-1,3-benzothiazol-2-ol	Not in list	C7H4FNOS	Fc1ccc2nc(O)sc2c1	InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluoro-2-hydroxybenzothiazole			6-fluoro-1,3-benzothiazol-2-ol	Not in list	C7H4FNOS	Fc1ccc2nc(O)sc2c1	InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluoro-2-hydroxybenzothiazole			6-fluoro-1,3-benzothiazol-2-ol	Not in list	C7H4FNOS	Fc1ccc2nc(O)sc2c1	InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluoro-2-hydroxybenzothiazole			6-fluoro-1,3-benzothiazol-2-ol	Not in list	C7H4FNOS	Fc1ccc2nc(O)sc2c1	InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluoro-2-hydroxybenzothiazole			6-fluoro-1,3-benzothiazol-2-ol	Not in list	C7H4FNOS	Fc1ccc2nc(O)sc2c1	InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluoro-2-hydroxybenzothiazole			6-fluoro-1,3-benzothiazol-2-ol	Not in list	C7H4FNOS	Fc1ccc2nc(O)sc2c1	InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluoro-2-hydroxybenzothiazole			6-fluoro-1,3-benzothiazol-2-ol	Not in list	C7H4FNOS	Fc1ccc2nc(O)sc2c1	InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluoro-2-hydroxybenzothiazole			6-fluoro-1,3-benzothiazol-2-ol	Not in list	C7H4FNOS	Fc1ccc2nc(O)sc2c1	InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluoro-2-hydroxybenzothiazole			6-fluoro-1,3-benzothiazol-2-ol	Not in list	C7H4FNOS	Fc1ccc2nc(O)sc2c1	InChI=1/C7H4FNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluorobenzothiazol-2-yl methyl ketone			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone	Not in list	C9H6FNOS	CC(=O)c1nc2ccc(F)cc2s1	InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluorobenzothiazol-2-yl methyl ketone			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone	Not in list	C9H6FNOS	CC(=O)c1nc2ccc(F)cc2s1	InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluorobenzothiazol-2-yl methyl ketone			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone	Not in list	C9H6FNOS	CC(=O)c1nc2ccc(F)cc2s1	InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluorobenzothiazol-2-yl methyl ketone			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone	Not in list	C9H6FNOS	CC(=O)c1nc2ccc(F)cc2s1	InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluorobenzothiazol-2-yl methyl ketone			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone	Not in list	C9H6FNOS	CC(=O)c1nc2ccc(F)cc2s1	InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluorobenzothiazol-2-yl methyl ketone			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone	Not in list	C9H6FNOS	CC(=O)c1nc2ccc(F)cc2s1	InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluorobenzothiazol-2-yl methyl ketone			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone	Not in list	C9H6FNOS	CC(=O)c1nc2ccc(F)cc2s1	InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluorobenzothiazol-2-yl methyl ketone			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone	Not in list	C9H6FNOS	CC(=O)c1nc2ccc(F)cc2s1	InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluorobenzothiazol-2-yl methyl ketone			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone	Not in list	C9H6FNOS	CC(=O)c1nc2ccc(F)cc2s1	InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6-Fluorobenzothiazol-2-yl methyl ketone			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanone	Not in list	C9H6FNOS	CC(=O)c1nc2ccc(F)cc2s1	InChI=1/C9H6FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-4H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	1-(6-Fluorobenzothiazol-2-yl)ethanol			1-(6-fluoro-1,3-benzothiazol-2-yl)ethanol	Not in list	C9H8FNOS	CC(O)c1nc2ccc(F)cc2s1	InChI=1/C9H8FNOS/c1-5(12)9-11-7-3-2-6(10)4-8(7)13-9/h2-5,12H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate			Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate	Not in list	C18H24FN3O4S	CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1	InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate			Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate	Not in list	C18H24FN3O4S	CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1	InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate			Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate	Not in list	C18H24FN3O4S	CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1	InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate			Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate	Not in list	C18H24FN3O4S	CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1	InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate			Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate	Not in list	C18H24FN3O4S	CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1	InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate			Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate	Not in list	C18H24FN3O4S	CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1	InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate			Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate	Not in list	C18H24FN3O4S	CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1	InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate			Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate	Not in list	C18H24FN3O4S	CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1	InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate			Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate	Not in list	C18H24FN3O4S	CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1	InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate			Isopropyl (1S)-1-[(1R or S)-1-(6-fluoro-5-hydroxybenzothiazol-2-yl)ethylcarbamoyl]-2-methylpropylcarbamate	Not in list	C18H24FN3O4S	CC(C)C(NC(=O)OC(C)C)C(=O)NC(C)c1nc2cc(O)c(F)cc2s1	InChI=1/C18H24FN3O4S/c1-8(2)15(22-18(25)26-9(3)4)16(24)20-10(5)17-21-12-7-13(23)11(19)6-14(12)27-17/h6-10,15,23H,1-5H3,(H,20,24)(H,22,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar	4	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	48	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	48	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	48	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is identical to the substance	Clomazone		81777-89-1	2-(2-chlorobenzyl)-4,4-dimethylisoxazolidin-3-one	Clomazone	C12H14ClNO2	O=C1N(CC(C=CC=C2)=C2Cl)OCC(C)1C	InChI=1S/C12H14ClNO2/c1-12(2)8-16-14(11(12)15)7-9-5-3-4-6-10(9)13/h3-6H,7-8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is a metabolite of the substance	Isoxazolidine		81778-07-6	4,4-dimethyl-1,2-oxazolidin-3-one	Not in list	C5H9NO2	CC1(CONC1=O)C	InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is a metabolite of the substance	Isoxazolidine		81778-07-6	4,4-dimethyl-1,2-oxazolidin-3-one	Not in list	C5H9NO2	CC1(CONC1=O)C	InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is a metabolite of the substance	Isoxazolidine		81778-07-6	4,4-dimethyl-1,2-oxazolidin-3-one	Not in list	C5H9NO2	CC1(CONC1=O)C	InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is a metabolite of the substance	Isoxazolidine		81778-07-6	4,4-dimethyl-1,2-oxazolidin-3-one	Not in list	C5H9NO2	CC1(CONC1=O)C	InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is a metabolite of the substance	Isoxazolidine		81778-07-6	4,4-dimethyl-1,2-oxazolidin-3-one	Not in list	C5H9NO2	CC1(CONC1=O)C	InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is a metabolite of the substance	Isoxazolidine		81778-07-6	4,4-dimethyl-1,2-oxazolidin-3-one	Not in list	C5H9NO2	CC1(CONC1=O)C	InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is a metabolite of the substance	Isoxazolidine		81778-07-6	4,4-dimethyl-1,2-oxazolidin-3-one	Not in list	C5H9NO2	CC1(CONC1=O)C	InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is a metabolite of the substance	Isoxazolidine		81778-07-6	4,4-dimethyl-1,2-oxazolidin-3-one	Not in list	C5H9NO2	CC1(CONC1=O)C	InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is a metabolite of the substance	Isoxazolidine		81778-07-6	4,4-dimethyl-1,2-oxazolidin-3-one	Not in list	C5H9NO2	CC1(CONC1=O)C	InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Clomazone		81777-89-1	single chemical entity	Component is a metabolite of the substance	Isoxazolidine		81778-07-6	4,4-dimethyl-1,2-oxazolidin-3-one	Not in list	C5H9NO2	CC1(CONC1=O)C	InChI=1S/C5H9NO2/c1-5(2)3-8-6-4(5)7/h3H2,1-2H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Clomazone	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clomazone	17Aug2007	2007	doi:10.2903/j.efsa.2007.109r
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	with	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			no data	without	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			no data	with	Negative			RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI		Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Not reported	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Not reported	10	Male/Female	oral: gavage	12.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Diclofop-methyl	257-141-8	51338-27-3	single chemical entity	Component is identical to the substance	Diclofop-methyl	257-141-8	51338-27-3	Methyl 2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate	Diclofop-Methyl	C16H14Cl2O4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)Cl)Cl	InChI=1S/C16H14Cl2O4/c1-10(16(19)20-2)21-12-4-6-13(7-5-12)22-15-8-3-11(17)9-14(15)18/h3-10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Not reported	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Diclofop-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diclofop (considered variant diclofop-methyl)	07Oct2010	2010	doi:10.2903/j.efsa.2010.1718
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is identical to the substance	Chlorsulfuron	265-268-5	64902-72-3	2-chloro-N-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino]carbonyl}benzenesulfonamide	Chlorsulfuron	C12H12ClN5O4S	Cc2nc(NC(=O)NS(=O)(=O)c1ccccc1Cl)nc(OC)n2	InChI=1S/C12H12ClN5O4S/c1-7-14-10(17-12(15-7)22-2)16-11(19)18-23(20,21)9-6-4-3-5-8(9)13/h3-6H,1-2H3,(H2,14,15,16,17,18,19)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: feed	10.0000000000	week	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	2-chlorobenzenesulfonamide	230-156-7	6961-82-6	2-chlorobenzenesulfonamide	Not in list	C6H6ClNO2S	C1=CC=C(C(=C1)S(=O)(=O)N)Cl	InChI=1S/C6H6ClNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Chlorsulfuron	265-268-5	64902-72-3	single chemical entity	Component is a metabolite of the substance	N-[(Ncarbamoylcarbamimidoyl)carbamoyl]-2-chlorobenzenesulfonamide			N'-(N-{[(2-chlorophenyl)sulfonyl]carbamoyl}carbamimidoyl)carbamimidic acid	Not in list	C9H10ClN5O4S	O=S(=O)(NC(=O)NC(=N)/N=C(\N)O)c1ccccc1Cl	InChI=1/C9H10ClN5O4S/c10-5-3-1-2-4-6(5)20(18,19)15-9(17)14-7(11)13-8(12)16/h1-4H,(H6,11,12,13,14,15,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorsulfuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlorsulfuron	06Mar2009	2009	doi:10.2903/j.efsa.2009.201r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	ICR	10	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA1530			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	with	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	5.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Clopyralid	216-935-4	1702-17-6	single chemical entity	Component is identical to the substance	Clopyralid	216-935-4	1702-17-6	3,6-dichloropyridine-2-carboxylic acid	Clopyralid	C6H3Cl2NO2	C1=CC(=NC(=C1Cl)C(=O)O)Cl	InChI=1S/C6H3Cl2NO2/c7-3-1-2-4(8)9-5(3)6(10)11/h1-2H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	5.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Clopyralid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Clopyralid	23Jan2006	2006	doi: 10.2903/j.efsa.2006.50r
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is identical to the substance	Cyhalofop-butyl	601-817-0	122008-85-9	butyl (2R)-2-[4-(4-cyano-2-fluorophenoxy)phenoxy]propanoate	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C20H20FNO4	CCCCOC(=O)C(C)OC1=CC=C(C=C1)OC2=C(C=C(C=C2)C#N)F	InChI=1S/C20H20FNO4/c1-3-4-11-24-20(23)14(2)25-16-6-8-17(9-7-16)26-19-10-5-15(13-22)12-18(19)21/h5-10,12,14H,3-4,11H2,1-2H3/t14-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Italy	Cyhalofop-butyl	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	3T3			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	3T3			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Diflubenzuron	252-529-3	35367-38-5	single chemical entity	Component is identical to the substance	Diflubenzuron	252-529-3	35367-38-5	N-[(4-chlorophenyl)carbamoyl]-2,6-difluorobenzamide	Diflubenzuron	C14H9ClF2N2O2	Fc1cccc(F)c1C(=O)NC(=O)Nc2ccc(Cl)cc2	InChI=1/C14H9ClF2N2O2/c15-8-4-6-9(7-5-8)18-14(21)19-13(20)12-10(16)2-1-3-11(12)17/h1-7H,(H2,18,19,20,21)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	SwissWebster	5	Male	oral: unspecified	30.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Sweden	Diflubenzuron (Addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance diflubenzuron	07Sep2012	2012	doi:10.2903/j.efsa.2012.2870
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is a metabolite of the substance	(RS) 2-phenylcarbamoyl-propionic acid			{2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid	Not in list	C11H12N2O5	O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1	InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is a metabolite of the substance	(RS) 2-phenylcarbamoyl-propionic acid			{2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid	Not in list	C11H12N2O5	O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1	InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is a metabolite of the substance	(RS) 2-phenylcarbamoyl-propionic acid			{2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid	Not in list	C11H12N2O5	O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1	InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is a metabolite of the substance	(RS) 2-phenylcarbamoyl-propionic acid			{2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid	Not in list	C11H12N2O5	O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1	InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is a metabolite of the substance	(RS) 2-phenylcarbamoyl-propionic acid			{2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid	Not in list	C11H12N2O5	O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1	InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is a metabolite of the substance	(RS) 2-phenylcarbamoyl-propionic acid			{2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid	Not in list	C11H12N2O5	O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1	InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is a metabolite of the substance	(RS) 2-phenylcarbamoyl-propionic acid			{2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid	Not in list	C11H12N2O5	O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1	InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is a metabolite of the substance	(RS) 2-phenylcarbamoyl-propionic acid			{2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid	Not in list	C11H12N2O5	O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1	InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is a metabolite of the substance	(RS) 2-phenylcarbamoyl-propionic acid			{2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid	Not in list	C11H12N2O5	O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1	InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carbetamide	240-286-6	16118-49-3	single chemical entity	Component is a metabolite of the substance	(RS) 2-phenylcarbamoyl-propionic acid			{2-[(phenylcarbamoyl)oxy]propanoyl}carbamic acid	Not in list	C11H12N2O5	O=C(O)NC(=O)C(C)OC(=O)Nc1ccccc1	InChI=1/C11H12N2O5/c1-7(9(14)13-10(15)16)18-11(17)12-8-5-3-2-4-6-8/h2-7H,1H3,(H,12,17)(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Carbetamide (Revised DAR of December 2005)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbetamide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1913
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is a metabolite of the substance	2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide			2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxamide 4-oxide	Carboxin metabolite (P/V-54)	C6H9NO3S	CC=1OCCS(=O)C=1C(N)=O	InChI=1/C6H9NO3S/c1-4-5(6(7)8)11(9)3-2-10-4/h2-3H2,1H3,(H2,7,8)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Carboxin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	3	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Carboxin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Carboxin	226-031-1	5234-68-4	single chemical entity	Component is identical to the substance	Carboxin	226-031-1	5234-68-4	2-methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide	Carboxin	C12H13NO2S	CC1=C(SCCO1)C(=O)Nc2ccccc2	InChI=1/C12H13NO2S/c1-9-11(16-8-7-15-9)12(14)13-10-5-3-2-4-6-10/h2-6H,7-8H2,1H3,(H,13,14)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	3	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Carboxin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carboxin	18Oct2010	2010	doi:10.2903/j.efsa.2010.1857
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	24	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	24	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	24	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	5	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Dichlorprop-P		15165-67-0	single chemical entity	Component is identical to the substance	Dichlorprop-P		15165-67-0	(2R)-2-(2,4-dichlorophenoxy)propanoic acid	Dichlorprop-p	C9H8Cl2O3	Clc1cc(Cl)ccc1O[C@H](C)C(=O)O	InChI=1S/C9H8Cl2O3/c1-5(9(12)13)14-8-3-2-6(10)4-7(8)11/h2-5H,1H3,(H,12,13)/t5-/m1/s1	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	5	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Dichlorprop-p	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dichlorprop-P	13Nov2012	2012	doi:10.2903/j.efsa.2012.2950
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	intraperitoneal	6.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Ambiguous			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is a metabolite of the substance	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	609-284-6	36701-89-0	2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylic acid	Not in list	C13H8F3NO3	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)O)C(F)(F)F	InChI=1S/C13H8F3NO3/c14-13(15,16)8-3-1-4-9(7-8)20-11-10(12(18)19)5-2-6-17-11/h1-7H,(H,18,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Ambiguous			RMS: The United Kingdom	Diflufenican	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	House mouse (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Not reported	3	Male/Female	oral: unspecified			yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Cyromazine		66215-27-8	single chemical entity	Component is identical to the substance	Cyromazine		66215-27-8	N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine	Cyromazine	C6H10N6	Nc2nc(N)nc(NC1CC1)n2	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	mouse spot test	in vivo	Equivalent or similar to	OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test)	Yes	Acceptable	House mouse (as animal)	C57BL	71	Female	intraperitoneal	8.0000000000	week	yes, concurrent vehicle	not applicable	Inconclusive			RMS: Greece	Cyromazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyromazine	21Oct2008	2008	doi:10.2903/j.efsa.2008.168r
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Positive			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Positive			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Positive			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Positive			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Positive			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Ambiguous			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Ambiguous			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar		Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar		Male	oral: gavage	16.0000000000	h	yes	not applicable	Negative			RMS: Spain	Dicloran	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Dicloran	202-746-4	99-30-9	single chemical entity	Component is identical to the substance	Dicloran	202-746-4	99-30-9	2,6-dichloro-4-nitroaniline	Dicloran	C6H4Cl2N2O2	Nc1c(Cl)cc(cc1Cl)[N+](=O)[O-]	InChI=1/C6H4Cl2N2O2/c7-4-1-3(10(11)12)2-5(8)6(4)9/h1-2H,9H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Spain	Dicloran (Addendum II)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicloran	03Aug2010	2010	doi:10.2903/j.efsa.2010.1698
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: unspecified	6.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Didecyldimethylammonium chloride	230-525-2	7173-51-5	single chemical entity	Component is identical to the substance	Didecyldimethylammonium chloride	230-525-2	7173-51-5	N-decyl-N,N-dimethyldecan-1-aminium chloride	Didecyldimethylammonium chloride (mixture of alkyl-quaternary ammonium salts with alkyl chain lengths of C8, C10 and C12)	C22H48N.Cl	[Cl-].CCCCCCCCCC[N+](C)(C)CCCCCCCCCC	InChI=1/C22H48N.ClH/c1-5-7-9-11-13-15-17-19-21-23(3,4)22-20-18-16-14-12-10-8-6-2;/h5-22H2,1-4H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The Netherlands	Didecyldimethylammonium Chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance didecyldimethylammonium chloride	03Apr2009	2009	doi: 10.2903/j.efsa.2009.214r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Diazinon	206-373-8	333-41-5	single chemical entity	Component is identical to the substance	Diazinon	206-373-8	333-41-5	O,O-diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) thiophosphate	Diazinon	C12H21N2O3PS	CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C	InChI=1/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	16	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Diazinon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diazinon	09Aug2006	2006	doi:10.2903/j.efsa.2006.85r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	without	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	with	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	with	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	without	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	30	Male	oral: feed	10.0000000000	week	yes	not applicable	Negative			RMS: The United Kingdom	Clofentezine	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clodinafop-propargyl		105512-06-9	single chemical entity	Component is identical to the substance	Clodinafop-propargyl		105512-06-9	prop-2-yn-1-yl (2R)-2-{4-[(5-chloro-3-fluoropyridin-2-yl)oxy]phenoxy}propanoate	Clodinafop-Propargyl	C17H13ClFNO4	O=C(OCC#C)[C@H](OC1=CC=C(OC2=NC=C(Cl)C=C2F)C=C1)C	InChI=1S/C17H13ClFNO4/c1-3-8-22-17(21)11(2)23-13-4-6-14(7-5-13)24-16-15(19)9-12(18)10-20-16/h1,4-7,9-11H,8H2,2H3/t11-/m1/s1	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The Netherlands	Clodinafop-propargyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clodinafop	31Aug2005	2005	doi:10.2903/j.efsa.2005.34ar
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	5	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	5	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	5	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Cymoxanil	261-043-0	57966-95-7	single chemical entity	Component is identical to the substance	Cymoxanil	261-043-0	57966-95-7	(1E)-2-(ethylcarbamoylamino)-N-methoxy-2-oxoethanimidoyl cyanide	Cymoxanil	C7H10N4O3	CCNC(=O)NC(=O)/C(=N/OC)/C#N	InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	5	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Cymoxanil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cymoxanil	17Oct2008	2008	doi:10.2903/j.efsa.2008.167r
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Ambiguous			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Ambiguous			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley		Male	oral: unspecified	4.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley		Male	oral: unspecified	12.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	CD-1	105	Male	oral: gavage	5.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	with	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is a metabolite of the substance	1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium			1-oxo-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium	Not in list	C8H9N2O	O=C1NCC[n+]2ccccc12	InChI=1/C8H8N2O/c11-8-7-3-1-2-5-10(7)6-4-9-8/h1-3,5H,4,6H2/p+1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodemorph acetate	250-778-2	31717-87-0	single chemical entity	Component is identical to the substance	Dodemorph acetate	250-778-2	31717-87-0	Acetic acid;4-cyclododecyl-2,6-dimethylmorpholine	Not in list	C20H39NO3	CC1CN(CC(O1)C)C2CCCCCCCCCCC2.CC(=O)O	InChI=1S/C18H35NO.C2H4O2/c1-16-14-19(15-17(2)20-16)18-12-10-8-6-4-3-5-7-9-11-13-18;1-2(3)4/h16-18H,3-15H2,1-2H3;1H3,(H,3,4)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Dodemorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dodemorph (considered variant dodemorph acetate)	17Oct2008	2008	doi:10.2903/j.efsa.2008.170r
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Epoxiconazole		106325-08-0	single chemical entity	Component is identical to the substance	Epoxiconazole		106325-08-0	1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole	Epoxiconazole	C17H13ClFN3O	ClC3=C(C=CC=C3)C1OC(C4=CC=C(F)C=C4)1CN2N=CN=C2	InChI=1S/C17H13ClFN3O/c18-15-4-2-1-3-14(15)16-17(23-16,9-22-11-20-10-21-22)12-5-7-13(19)8-6-12/h1-8,10-11,16H,9H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Epoxiconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance epoxiconazole	28Jul2008	2008	doi:10.2903/j.efsa.2008.138r
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	no information		RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	no information		RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is a metabolite of the substance	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid		7600-50-2	2,5-dichloro-3-hydroxy-6-methoxybenzoic acid	Not in list	C8H6Cl2O4	COC1=C(C=C(C(=C1C(=O)O)Cl)O)Cl	InChI=1S/C8H6Cl2O4/c1-14-7-3(9)2-4(11)6(10)5(7)8(12)13/h2,11H,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	3	Male	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	3	Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is identical to the substance	Esfenvalerate		66230-04-4	(alphaS)-alpha-cyano-3-phenoxybenzyl(2S)-2-(4-chlorophenyl)-3-methylbutyrate	Esfenvalerate	C25H22ClNO3	CC(C)C(C1=CC=C(C=C1)Cl)C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3/t23-,24+/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile		66753-10-4	3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C24H22ClNO	CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile		66753-10-4	3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C24H22ClNO	CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile		66753-10-4	3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C24H22ClNO	CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile		66753-10-4	3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C24H22ClNO	CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile		66753-10-4	3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C24H22ClNO	CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile		66753-10-4	3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C24H22ClNO	CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile		66753-10-4	3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C24H22ClNO	CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile		66753-10-4	3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C24H22ClNO	CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile		66753-10-4	3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C24H22ClNO	CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(2RS,3RS)-3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile		66753-10-4	3-(4-chlorophenyl)-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C24H22ClNO	CC(C)C(C1=CC=C(C=C1)Cl)C(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C24H22ClNO/c1-17(2)24(18-11-13-20(25)14-12-18)23(16-26)19-7-6-10-22(15-19)27-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate			(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate	Not in list	C25H24ClNO4	Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O	InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate			(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate	Not in list	C25H24ClNO4	Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O	InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate			(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate	Not in list	C25H24ClNO4	Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O	InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate			(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate	Not in list	C25H24ClNO4	Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O	InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate			(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate	Not in list	C25H24ClNO4	Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O	InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate			(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate	Not in list	C25H24ClNO4	Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O	InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate			(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate	Not in list	C25H24ClNO4	Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O	InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate			(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate	Not in list	C25H24ClNO4	Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O	InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate			(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate	Not in list	C25H24ClNO4	Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O	InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Esfenvalerate		66230-04-4	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate			(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (2RS)-2-(4-chlorophenyl)-3-methylbutanoate	Not in list	C25H24ClNO4	Clc1ccc(cc1)C(C(C)C)C(=O)OC(c3cccc(Oc2ccccc2)c3)C(N)=O	InChI=1/C25H24ClNO4/c1-16(2)22(17-11-13-19(26)14-12-17)25(29)31-23(24(27)28)18-7-6-10-21(15-18)30-20-8-4-3-5-9-20/h3-16,22-23H,1-2H3,(H2,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Esfenvalerate	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance esfenvalerate	03Nov2014	2014	doi:10.2903/j.efsa.2014.3873
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	CM571			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP67			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	CM611			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP6			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Ambiguous			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D6			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D6			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	36	Male/Female	Not reported	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	36	Male/Female	Not reported	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	36	Male/Female	Not reported	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	42	Male/Female	Not reported	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	42	Male/Female	Not reported	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	42	Male/Female	Not reported	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	Not reported	2.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	Not reported	16.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	4	Male	Not reported	24.0000000000	h	yes	not applicable	Positive			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	4	Male	Not reported	39.0000000000	h	yes	not applicable	Positive			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is identical to the substance	Etridiazole	219-991-8	2593-15-9	5-ethoxy-3-(trichloromethyl)-1,2,4-thiadiazole	Etridiazole	C5H5Cl3N2OS	ClC(Cl)(Cl)C1=NSC(OCC)=N1	InChI=1S/C5H5Cl3N2OS/c1-2-11-4-9-3(10-12-4)5(6,7)8/h2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	4	Male	Not reported	48.0000000000	h	yes	not applicable	Positive			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	30	Male/Female	Not reported	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Etridiazole	219-991-8	2593-15-9	single chemical entity	Component is a metabolite of the substance	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid		67472-43-9	5-Ethoxy-1,2,4-thiadiazole-3-carboxylic acid	Not in list	C5H6N2O3S	CCOC1=NC(=NS1)C(=O)O	InChI=1S/C5H6N2O3S/c1-2-10-5-6-3(4(8)9)7-11-5/h2H2,1H3,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	30	Male/Female	Not reported	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Etridiazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance etridiazole	04Oct2010	2010	doi:10.2903/j.efsa.2010.1823
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	20	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	20	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is identical to the substance	Cyflufenamid		180409-60-3	N-[(cyclopropylmethoxyamino)-[2,3-difluoro-6-(trifluoromethyl)phenyl]methylidene]-2-phenylacetamide	Cyflufenamid: sum of cyflufenamid (Z-isomer) and its E-isomer	C20H17F5N2O2	C1CC1CONC(=NC(=O)CC2=CC=CC=C2)C3=C(C=CC(=C3F)F)C(F)(F)F	InChI=1S/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			N'-(cyclopropylmethoxy)-2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C12H11F5N2O	N/C(=N\OCC1CC1)c2c(ccc(F)c2F)C(F)(F)F	InChI=1/C12H11F5N2O/c13-8-4-3-7(12(15,16)17)9(10(8)14)11(18)19-20-5-6-1-2-6/h3-4,6H,1-2,5H2,(H2,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide			2,3-difluoro-6-(trifluoromethyl)benzenecarboximidamide	Not in list	C8H5F5N2	Fc1c(C(=N)N)c(ccc1F)C(F)(F)F	InChI=1/C8H5F5N2/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H3,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	2,3-difluoro-6-(trifluoromethyl)benzamide			2,3-difluoro-6-(trifluoromethyl)benzamide	Not in list	C8H4F5NO	Fc1c(C(N)=O)c(ccc1F)C(F)(F)F	InChI=1/C8H4F5NO/c9-4-2-1-3(8(11,12)13)5(6(4)10)7(14)15/h1-2H,(H2,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid			3-({(Z)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}amino)-3-oxopropanoic acid	Not in list	C15H13F5N2O4	FC(F)(F)c2ccc(F)c(F)c2C(\NC(=O)CC(=O)O)=N\OCC1CC1	InChI=1/C15H13F5N2O4/c16-9-4-3-8(15(18,19)20)12(13(9)17)14(21-10(23)5-11(24)25)22-26-6-7-1-2-7/h3-4,7H,1-2,5-6H2,(H,24,25)(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide			N-{(E)-[(cyclopropylmethoxy)imino][2,3-difluoro-6-(trifluoromethyl)phenyl]methyl}-2-phenylacetamide	Not in list	C20H17F5N2O2	FC(F)(F)c3ccc(F)c(F)c3C(/NC(=O)Cc1ccccc1)=N\OCC2CC2	InChI=1/C20H17F5N2O2/c21-15-9-8-14(20(23,24)25)17(18(15)22)19(27-29-11-13-6-7-13)26-16(28)10-12-4-2-1-3-5-12/h1-5,8-9,13H,6-7,10-11H2,(H,26,27,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropanecarboxylic acid	217-162-5	1759-53	cyclopropanecarboxylic acid	Not in list	C4H6O2	C1CC1C(=O)O	InChI=1S/C4H6O2/c5-4(6)3-1-2-3/h3H,1-2H2,(H,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyflufenamid		180409-60-3	single chemical entity	Component is a metabolite of the substance	cyclopropylmethanol	219-735-5	2516-33-8	cyclopropylmethanol	Not in list	C4H8O	C1CC1CO	InChI=1S/C4H8O/c5-3-4-1-2-4/h4-5H,1-3H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Cyflufenamid	2006	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance cyflufenamid	29May2009	2009	doi:10.2903/j.efsa.2009.258r
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Not reported			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Not reported			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Hamster (as animal)	embryo cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	20	Male	oral: gavage	5.0000000000	D	yes	not applicable	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid			(2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid	Not in list	C15H16ClN3O3	OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2	InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid			(2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid	Not in list	C15H16ClN3O3	OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2	InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid			(2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid	Not in list	C15H16ClN3O3	OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2	InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid			(2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid	Not in list	C15H16ClN3O3	OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2	InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid			(2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid	Not in list	C15H16ClN3O3	OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2	InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid			(2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid	Not in list	C15H16ClN3O3	OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2	InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid			(2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid	Not in list	C15H16ClN3O3	OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2	InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid			(2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid	Not in list	C15H16ClN3O3	OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2	InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid			(2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid	Not in list	C15H16ClN3O3	OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2	InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)-2-hexanoic acid			(2E)-5-(4-chlorophenyl)-5-hydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hex-2-enoic acid	Not in list	C15H16ClN3O3	OC(Cn1cncn1)(C(C)/C=C/C(=O)O)c2ccc(Cl)cc2	InChI=1/C15H16ClN3O3/c1-11(2-7-14(20)21)15(22,8-19-10-17-9-18-19)12-3-5-13(16)6-4-12/h2-7,9-11,22H,8H2,1H3,(H,20,21)/b7-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is identical to the substance	Cyproconazole		94361-06-5	2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Cyproconazole	C15H18ClN3O	ClC1=CC=C(C(CN2C=NC=N2)(C(C)C3CC3)O)C=C1	InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Ireland	Cyproconazole (Addendum to the Draft Report and Proposed Decision)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is identical to the substance	Cyprodinil		121552-61-2	4-cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine	Cyprodinil	C14H15N3	CC1=NC(NC3=CC=CC=C3)=NC(C2CC2)=C1	InChI=1S/C14H15N3/c1-10-9-13(11-7-8-11)17-14(15-10)16-12-5-3-2-4-6-12/h2-6,9,11H,7-8H2,1H3,(H,15,16,17)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-cyclopropyl-6-methyl-pyrimidine-2-ylamine		92238-61-4	4-cyclopropyl-6-methylpyrimidin-2-amine	Not in list	C8H11N3	CC1=NC(=NC(=C1)C2CC2)N	InChI=1S/C8H11N3/c1-5-4-7(6-2-3-6)11-8(9)10-5/h4,6H,2-3H2,1H3,(H2,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	3-(4-Cyclopropyl-6-methyl-pyrimidin-2-yl-amino)-phenol			3-[(4-cyclopropyl-6-methylpyrimidin-2-yl)amino]phenol	Not in list		Oc3cc(Nc1nc(C)cc(n1)C2CC2)ccc3	InChI=1S/C14H15N3O/c1-9-7-13(10-5-6-10)17-14(15-9)16-11-3-2-4-12(18)8-11/h2-4,7-8,10,18H,5-6H2,1H3,(H,15,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-Amino-6-cyclopropyl-pyrimidin-4-yl)-methanol			(2-amino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C8H11N3O	Nc1nc(cc(CO)n1)C2CC2	InChI=1/C8H11N3O/c9-8-10-6(4-12)3-7(11-8)5-1-2-5/h3,5,12H,1-2,4H2,(H2,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	4-Cyclopropyl-6-methyl-pyrimidin-2-ol			4-cyclopropyl-6-methylpyrimidin-2-ol	Not in list	C8H10N2O	Cc1cc(nc(O)n1)C2CC2	InChI=1/C8H10N2O/c1-5-4-7(6-2-3-6)10-8(11)9-5/h4,6H,2-3H2,1H3,(H,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Cyprodinil		121552-61-2	single chemical entity	Component is a metabolite of the substance	(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol			(2-anilino-6-cyclopropylpyrimidin-4-yl)methanol	Not in list	C14H15N3O	C1CC1C2=CC(=NC(=N2)NC3=CC=CC=C3)CO	InChI=1S/C14H15N3O/c18-9-12-8-13(10-6-7-10)17-14(16-12)15-11-4-2-1-3-5-11/h1-5,8,10,18H,6-7,9H2,(H,15,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Cypronidil	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyprodinil	30Jan2006	2006	doi:10.2903/j.efsa.2006.51r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			yes	without	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			yes	with	Negative			RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	30	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	30	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethomorph	404-200-2	110488-70-5	single chemical entity	Component is identical to the substance	Dimethomorph	404-200-2	110488-70-5	(E)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one	Dimethomorph (sum of isomers)	C21H22ClNO4	COC1=C(C=C(C=C1)/C(=C/C(=O)N2CCOCC2)/C3=CC=C(C=C3)Cl)OC	InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+	organic	representative isomer	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	30	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Germany	Dimethomorph	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethomorph	21Jul2006	2006	doi:10.2903/j.efsa.2006.82r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)oxalamic acid			[(2,6-dimethylphenyl)(2-methoxyethyl)amino](oxo)acetic acid	Not in list	C13H17NO4	O=C(O)C(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H17NO4/c1-9-5-4-6-10(2)11(9)14(7-8-18-3)12(15)13(16)17/h4-6H,7-8H2,1-3H3,(H,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative	no information		RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-methoxyethyl) carbamoyl]methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxyethyl)amino]-2-oxoethanesulfonate	Not in list	C13H18NNaO5S	O=S(=O)(O[Na])CC(=O)N(CCOC)c1c(C)cccc1C	InChI=1/C13H19NO5S.Na/c1-10-5-4-6-11(2)13(10)14(7-8-19-3)12(15)9-20(16,17)18;/h4-6H,7-9H2,1-3H3,(H,16,17,18);/q;+1/p-1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative	no information		RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	(2,6-dimethylphenylcarbamoyl)-methanesulfonic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)amino]-2-oxoethanesulfonate	Not in list	C10H12NNaO4S	O=C(Nc1c(C)cccc1C)CS(=O)(=O)O[Na]	InChI=1/C10H13NO4S.Na/c1-7-4-3-5-8(2)10(7)11-9(12)6-16(13,14)15;/h3-5H,6H2,1-2H3,(H,11,12)(H,13,14,15);/q;+1/p-1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	[(2,6-dimethylphenyl)-(2-sulfoacetyl)amino]acetic acid sodium salt			sodium 2-[(2,6-dimethylphenyl)(2-methoxy-2-oxoethyl)amino]-2-oxoethanesulfonate	Not in list	C13H16NnaO6S	O=S(=O)(O[Na])CC(=O)N(CC(=O)OC)c1c(C)cccc1C	InChI=1/C13H17NO6S.Na/c1-9-5-4-6-10(2)13(9)14(7-12(16)20-3)11(15)8-21(17,18)19;/h4-6H,7-8H2,1-3H3,(H,17,18,19);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	3-{2-[(2,6-dimethyl-phenyl)-(2-hydroxyacetyl)amino]ethylsulfanyl}-2-hydroxypropionic acid			3-({2-[(2,6-dimethylphenyl)(hydroxyacetyl)amino]ethyl}sulfanyl)-2-hydroxypropanoic acid	Not in list	C15H21NO5S	O=C(O)C(O)CSCCN(C(=O)CO)c1c(C)cccc1C	InChI=1/C15H21NO5S/c1-10-4-3-5-11(2)14(10)16(13(19)8-17)6-7-22-9-12(18)15(20)21/h3-5,12,17-18H,6-9H2,1-2H3,(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is a metabolite of the substance	2-[(2-hydroxyacetyl)-(2-methoxyethyl)amino]-3-methylbenzoic acid			2-[(hydroxyacetyl)(2-methoxyethyl)amino]-3-methylbenzoic acid	Not in list	C13H17NO5	OCC(=O)N(CCOC)c1c(C)cccc1C(=O)O	InChI=1/C13H17NO5/c1-9-4-3-5-10(13(17)18)12(9)14(6-7-19-2)11(16)8-15/h3-5,15H,6-8H2,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Dimethachlor	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Dimethachlor	256-625-6	50563-36-5	single chemical entity	Component is identical to the substance	Dimethachlor	256-625-6	50563-36-5	2-chloro-N-(2,6-dimethylphenyl)-N-(2-methoxyethyl)acetamide	Dimethachlor	C13H18ClNO2	ClCC(=O)N(CCOC)c1c(C)cccc1C	InChI=1S/C13H18ClNO2/c1-10-5-4-6-11(2)13(10)15(7-8-17-3)12(16)9-14/h4-6H,7-9H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Not reported	6	Male	oral: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Dimethachlor (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimethachlor	30Oct2008	2008	doi:10.2903/j.efsa.2008.169r
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Diethofencarb	403-870-3	87130-20-9	single chemical entity	Component is identical to the substance	Diethofencarb	403-870-3	87130-20-9	isopropyl (3,4-diethoxyphenyl)carbamate	Diethofencarb	C14H21NO4	O=C(OC(C)C)NC1=CC=C(OCC)C(OCC)=C1	InChI=1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Diethofencarb (Revised additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diethofencarb	20Sep2010	2010	doi:10.2903/j.efsa.2010.1721
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is identical to the substance	Etofenprox	407-980-2	80844-07-1	1-Ethoxy-4-[2-methyl-1-[(3-phenoxyphenyl)methoxy]propan-2-yl]benzene	Etofenprox	C25H28O3	CCOC1=CC=C(C=C1)C(C)(C)COCC2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H28O3/c1-4-27-22-15-13-21(14-16-22)25(2,3)19-26-18-20-9-8-12-24(17-20)28-23-10-6-5-7-11-23/h5-17H,4,18-19H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM871			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM871			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP67			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP67			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Etofenprox	407-980-2	80844-07-1	single chemical entity	Component is a metabolite of the substance	2-(4-ethoxyphenyl)-2-methylpropyl 3-phenoxybenzoate		117252-00-3	[2-(4-ethoxyphenyl)-2-methylpropyl] 3-phenoxybenzoate	Not in list	C25H26O4	CCOC1=CC=C(C=C1)C©©COC(=O)C2=CC(=CC=C2)OC3=CC=CC=C3	InChI=1S/C25H26O4/c1-4-27-21-15-13-20(14-16-21)25(2,3)18-28-24(26)19-9-8-12-23(17-19)29-22-10-6-5-7-11-22/h5-17H,4,18H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Italy	Etofenprox	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance etofenprox	01Apr2009	2009	doi:10.2903/j.efsa.2009.213r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is identical to the substance	Dimoxystrobin		149961-52-4	(2Z)-2-[2-[(2,5-dimethylphenoxy)methyl]phenyl]-2-methoxyimino-N-methylacetamide	Dimoxystrobin	C19H22N2O3	CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)NC	InChI=1S/C19H22N2O3/c1-13-9-10-14(2)17(11-13)24-12-15-7-5-6-8-16(15)18(21-23-4)19(22)20-3/h5-11H,12H2,1-4H3,(H,20,22)/b21-18-	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Dimoxystrobin		149961-52-4	single chemical entity	Component is a metabolite of the substance	((E)-2-(2-hydroxymethylphenyl)-2-methoxyimino-N-methyl-acetamide)			(2E)-2-[2-(hydroxymethyl)phenyl]-2-(methoxyimino)-N-methylacetamide	Not in list	C11H14N2O3	OCc1ccccc1/C(=N\OC)C(=O)NC	InChI=1S/C11H14N2O3/c1-12-11(15)10(13-16-2)9-6-4-3-5-8(9)7-14/h3-6,14H,7H2,1-2H3,(H,12,15)/b13-10+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimoxystrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dimoxystrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.46r
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Disodium phosphonate	237-249-1	13708-85-5	single chemical entity	Component is identical to the substance	Disodium phosphonate	237-249-1	13708-85-5	Disodium phosphonate	Not in list	H3O3P.2Na	[O-]P(=O)=O.[Na+].[Na+]	InChI=1S/2Na.HO3P/c;;1-4(2)3/h;;(H,1,2,3)/q2*+1;/p-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	12	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Disodium phosphonate (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance disodium phosphonate.	31May2013	2013	doi:10.2903/j.efsa.2013.3213
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	no data	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	no data	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is identical to the substance	Bitertanol	259-513-5	55179-31-2	1-(biphenyl-4-yloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Bitertanol	C20H23N3O2	CC(C)(C)C(O)C(Oc1ccc(cc1)c2ccccc2)n3cncn3	InChI=1S/C20H23N3O2/c1-20(2,3)18(24)19(23-14-21-13-22-23)25-17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-14,18-19,24H,1-3H3	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Inconclusive			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	with	Negative			RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Bifenthrin	617-373-6	82657-04-3	single chemical entity	Component is identical to the substance	Bifenthrin	617-373-6	82657-04-3	(2-methylbiphenyl-3-yl)methyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Bifenthrin	C23H22ClF3O2	O=C(OCC2=CC=CC(C3=CC=CC=C3)=C2C)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C23H22ClF3O2/c1-14-16(10-7-11-17(14)15-8-5-4-6-9-15)13-29-21(28)20-18(22(20,2)3)12-19(24)23(25,26)27/h4-12,18,20H,13H2,1-3H3/b19-12-	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Bifenthrin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bifenthrin	19May2011	2011	doi:10.2903/j.efsa.2011.2159
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	no data	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Positive	no information		RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Positive	no information		RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Positive	no information		RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Human (as organism)	HeLa cells			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Human (as organism)	fibroblast			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	oral: gavage			no data	not applicable	Negative		no evidence	RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	oral: unspecified			no data	not applicable	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Positive	no information		RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Positive	no information		RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	large colonies		RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	small colonies		RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	large colonies		RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	small colonies		RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	large colonies		RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	large colonies		RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	small colonies		RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	small colonies		RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	large colonies		RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	large colonies		RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	small colonies		RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-ol	216-350-4	1563-38-8	2,2-dimethyl-3H-1-benzofuran-7-ol	Not in list	C10H12O2	CC1(CC2=C(O1)C(=CC=C2)O)C	InChI=1S/C10H12O2/c1-10(2)6-7-4-3-5-8(11)9(7)12-10/h3-5,11H,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	small colonies		RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate		16655-82-6	(3-hydroxy-2,2-dimethyl-3H-1-benzofuran-7-yl) N-methylcarbamate	Not in list	C12H15NO4	CC1(C(C2=C(O1)C(=CC=C2)OC(=O)NC)O)C	InChI=1S/C12H15NO4/c1-12(2)10(14)7-5-4-6-8(9(7)17-12)16-11(15)13-3/h4-6,10,14H,1-3H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	4	Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Diphenylamine	204-539-4	122-39-4	single chemical entity	Component is identical to the substance	Diphenylamine	204-539-4	122-39-4	N-phenylaniline	Diphenylamine	C12H11N	N(c1ccccc1)c2ccccc2	InChI=1/C12H11N/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h1-10,13H	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	4	Male	oral: unspecified	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Ireland	Diphenylamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diphenylamine	25Jan2012	2012	doi:10.2903/j.efsa.2012.2486
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	with	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	without	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin benzoate		155569-91-8	-	Not in list	C56H81NO15	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)[NH2+]C)OC)OC)C)C.C1=CC=C(C=C1)C(=O)[O-]	InChI=1S/C49H75NO13.C7H6O2/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39;8-7(9)6-4-2-1-3-5-6/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3;1-5H,(H,8,9)/b14-13+,28-16+,33-15+;/t26-,27-,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43-,44+,45-,46+,48+,49+;/m0./s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin benzoate		155569-91-8	-	Not in list	C56H81NO15	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)[NH2+]C)OC)OC)C)C.C1=CC=C(C=C1)C(=O)[O-]	InChI=1S/C49H75NO13.C7H6O2/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39;8-7(9)6-4-2-1-3-5-6/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3;1-5H,(H,8,9)/b14-13+,28-16+,33-15+;/t26-,27-,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43-,44+,45-,46+,48+,49+;/m0./s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin Hydrochloride				Not in list				organic	no structure			DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin benzoate		155569-91-8	-	Not in list	C56H81NO15	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)[NH2+]C)OC)OC)C)C.C1=CC=C(C=C1)C(=O)[O-]	InChI=1S/C49H75NO13.C7H6O2/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39;8-7(9)6-4-2-1-3-5-6/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3;1-5H,(H,8,9)/b14-13+,28-16+,33-15+;/t26-,27-,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43-,44+,45-,46+,48+,49+;/m0./s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male	oral: gavage	48.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin benzoate		155569-91-8	-	Not in list	C56H81NO15	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)[NH2+]C)OC)OC)C)C.C1=CC=C(C=C1)C(=O)[O-]	InChI=1S/C49H75NO13.C7H6O2/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39;8-7(9)6-4-2-1-3-5-6/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3;1-5H,(H,8,9)/b14-13+,28-16+,33-15+;/t26-,27-,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43-,44+,45-,46+,48+,49+;/m0./s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male	oral: gavage	12.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Emamectin	605-015-1	119791-41-2	single chemical entity	Component is part of a group assessment	Emamectin benzoate		155569-91-8	-	Not in list	C56H81NO15	CCC(C)C1C(C=CC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)[NH2+]C)OC)OC)C)C.C1=CC=C(C=C1)C(=O)[O-]	InChI=1S/C49H75NO13.C7H6O2/c1-12-26(2)44-29(5)18-19-48(63-44)24-35-21-34(62-48)17-16-28(4)43(27(3)14-13-15-33-25-56-46-42(51)30(6)20-36(47(52)59-35)49(33,46)53)60-40-23-38(55-11)45(32(8)58-40)61-39-22-37(54-10)41(50-9)31(7)57-39;8-7(9)6-4-2-1-3-5-6/h13-16,18-20,26-27,29,31-32,34-46,50-51,53H,12,17,21-25H2,1-11H3;1-5H,(H,8,9)/b14-13+,28-16+,33-15+;/t26-,27-,29-,31-,32-,34+,35-,36-,37-,38-,39-,40-,41-,42+,43-,44+,45-,46+,48+,49+;/m0./s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male	oral: gavage	6.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Emamectin	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance emamectin	21Nov2012	2012	doi:10.2903/j.efsa.2012.2955
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is identical to the substance	Bispyribac-sodium		125401-92-5	Sodium;2,6-bis[(4,6-dimethoxypyrimidin-2-yl)oxy]benzoate	Not in list	C19H17N4NaO8	COC1=CC(=NC(=N1)OC2=C(C(=CC=C2)OC3=NC(=CC(=N3)OC)OC)C(=O)[O-])OC.[Na+]	InChI=1S/C19H18N4O8.Na/c1-26-12-8-13(27-2)21-18(20-12)30-10-6-5-7-11(16(10)17(24)25)31-19-22-14(28-3)9-15(23-19)29-4;/h5-9H,1-4H3,(H,24,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-hydroxy-4,6-dimethoxypyrimidine		13223-26-2	4,6-dimethoxy-1H-pyrimidin-2-one	Not in list	C6H8N2O3	COC1=CC(=NC(=O)N1)OC	InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-hydroxy-4,6-dimethoxypyrimidine		13223-26-2	4,6-dimethoxy-1H-pyrimidin-2-one	Not in list	C6H8N2O3	COC1=CC(=NC(=O)N1)OC	InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-hydroxy-4,6-dimethoxypyrimidine		13223-26-2	4,6-dimethoxy-1H-pyrimidin-2-one	Not in list	C6H8N2O3	COC1=CC(=NC(=O)N1)OC	InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-hydroxy-4,6-dimethoxypyrimidine		13223-26-2	4,6-dimethoxy-1H-pyrimidin-2-one	Not in list	C6H8N2O3	COC1=CC(=NC(=O)N1)OC	InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-hydroxy-4,6-dimethoxypyrimidine		13223-26-2	4,6-dimethoxy-1H-pyrimidin-2-one	Not in list	C6H8N2O3	COC1=CC(=NC(=O)N1)OC	InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-hydroxy-4,6-dimethoxypyrimidine		13223-26-2	4,6-dimethoxy-1H-pyrimidin-2-one	Not in list	C6H8N2O3	COC1=CC(=NC(=O)N1)OC	InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-hydroxy-4,6-dimethoxypyrimidine		13223-26-2	4,6-dimethoxy-1H-pyrimidin-2-one	Not in list	C6H8N2O3	COC1=CC(=NC(=O)N1)OC	InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-hydroxy-4,6-dimethoxypyrimidine		13223-26-2	4,6-dimethoxy-1H-pyrimidin-2-one	Not in list	C6H8N2O3	COC1=CC(=NC(=O)N1)OC	InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-hydroxy-4,6-dimethoxypyrimidine		13223-26-2	4,6-dimethoxy-1H-pyrimidin-2-one	Not in list	C6H8N2O3	COC1=CC(=NC(=O)N1)OC	InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-hydroxy-4,6-dimethoxypyrimidine		13223-26-2	4,6-dimethoxy-1H-pyrimidin-2-one	Not in list	C6H8N2O3	COC1=CC(=NC(=O)N1)OC	InChI=1S/C6H8N2O3/c1-10-4-3-5(11-2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2,4-dihydroxy-6-methoxypyrimidine		29458-38-6	6-methoxy-1H-pyrimidine-2,4-dione	Not in list	C5H6N2O3	COC1=CC(=O)NC(=O)N1	InChI=1S/C5H6N2O3/c1-10-4-2-3(8)6-5(9)7-4/h2H,1H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxy-5-hydroxypyrimidin-2-yl)oxy-6-(4,6-dimethoxypyrimidin-2-yl)oxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(5-hydroxy-4,6-dimethoxypyrimidin-2-yl)oxy]benzoic acid	Not in list	C19H18N4O9	COc1nc(nc(OC)c1)Oc3cccc(Oc2nc(OC)c(O)c(OC)n2)c3C(=O)O	InChI=1/C19H18N4O9/c1-27-11-8-12(28-2)21-18(20-11)31-9-6-5-7-10(13(9)17(25)26)32-19-22-15(29-3)14(24)16(23-19)30-4/h5-8,24H,1-4H3,(H,25,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	sodium 2-hydroxy-6-(4-hydroxy-6-methoxypyrimidin-2-yl)oxybenzoate			sodium 2-hydroxy-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C12H5N2NaO6	[Na+].[O-]C(=O)c2c(Oc1nc(O)cc(OC)n1)cccc2O	InChI=1/C12H10N2O6.Na/c1-19-9-5-8(16)13-12(14-9)20-7-4-2-3-6(15)10(7)11(17)18;/h2-5,15H,1H3,(H,17,18)(H,13,14,16);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid	Not in list	C13H12N2O3	O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O	InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid	Not in list	C13H12N2O3	O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O	InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid	Not in list	C13H12N2O3	O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O	InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid	Not in list	C13H12N2O3	O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O	InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid	Not in list	C13H12N2O3	O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O	InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid	Not in list	C13H12N2O3	O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O	InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid	Not in list	C13H12N2O3	O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O	InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid	Not in list	C13H12N2O3	O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O	InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid	Not in list	C13H12N2O3	O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O	InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	2-(4,6-dimethoxypyrimidin-2-yl)oxy-6-hydroxybenzoic acid			2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-hydroxybenzoic acid	Not in list	C13H12N2O3	O=C(O)c2c(Oc1nc(cc(OC)n1)OC)cccc2O	InChI=1/C13H12N2O6/c1-19-9-6-10(20-2)15-13(14-9)21-8-5-3-4-7(16)11(8)12(17)18/h3-6,16H,1-2H3,(H,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt			sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C18H15N4NaO8	[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O	InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt			sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C18H15N4NaO8	[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O	InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt			sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C18H15N4NaO8	[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O	InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt			sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C18H15N4NaO8	[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O	InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt			sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C18H15N4NaO8	[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O	InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt			sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C18H15N4NaO8	[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O	InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt			sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C18H15N4NaO8	[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O	InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt			sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C18H15N4NaO8	[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O	InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt			sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C18H15N4NaO8	[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O	InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Bispyribac-sodium		125401-92-5	single chemical entity	Component is a metabolite of the substance	benzoic acid, 2-[(4,6-dimethoxy-2-pyrimidinyl)oxy]-6-[(4-hydroxy-6-methoxy-2-pyrimidinyl)oxy],sodium salt			sodium 2-[(4,6-dimethoxypyrimidin-2-yl)oxy]-6-[(4-hydroxy-6-methoxypyrimidin-2-yl)oxy]benzoate	Not in list	C18H15N4NaO8	[Na+].Oc1nc(nc(OC)c1)Oc3cccc(Oc2nc(cc(OC)n2)OC)c3C([O-])=O	InChI=1/C18H16N4O8.Na/c1-26-12-7-11(23)19-17(20-12)29-9-5-4-6-10(15(9)16(24)25)30-18-21-13(27-2)8-14(22-18)28-3;/h4-8H,1-3H3,(H,24,25)(H,19,20,23);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Bispyribac-Sodium	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bispyribac (unless otherwise stated all data evaluated refer to the variant bispyribac-sodium)	25Oct2010	2010	doi:10.2903/j.efsa.2010.1692
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is a metabolite of the substance	6,6’-difluoro-2,2’-dibenzothiazole			6,6'-difluoro-2,2'-bibenzo[d]thiazole	Not in list	C14H6F2N2S2	Fc1ccc2nc(sc2c1)c3nc4ccc(F)cc4s3	InChI=1S/C14H6F2N2S2/c15-7-1-3-9-11(5-7)19-13(17-9)14-18-10-4-2-8(16)6-12(10)20-14/h1-6H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Positive			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Positive			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	12.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	House mouse (as animal)	B6C3F1	3	Male	Not reported	2.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is identical to the substance	Clethodim		99129-21-2	2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethylsulfanyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim	C17H26ClNO3S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)SCC)CC1=O	InChI=1S/C17H26ClNO3S/c1-4-14(19-22-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)23-5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	House mouse (as animal)	B6C3F1	3	Male	Not reported	16.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxy-2-(1-iminopropan-1-yl)cyclohex-2-en-1-one			5-[2-(ethylsulfonyl)propyl]-3-hydroxy-2-propanimidoylcyclohex-2-en-1-one	Clethodim-Imin-Sulfon	C14H23NO4S	CCC(=N)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1/C14H23NO4S/c1-4-11(15)14-12(16)7-10(8-13(14)17)6-9(3)20(18,19)5-2/h9-10,15-16H,4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3,5-dihydroxycyclohex-2-en-1-one	Clethodim, 5-Hydroxy-Sulfon	C17H26ClNO6S	OC1(CC(C)S(=O)(=O)CC)CC(O)=C(C(=O)C1)C(\CC)=N\OC\C=C\Cl	InChI=1S/C17H26ClNO6S/c1-4-13(19-25-8-6-7-18)16-14(20)10-17(22,11-15(16)21)9-12(3)26(23,24)5-2/h6-7,12,20,22H,4-5,8-11H2,1-3H3/b7-6+,19-13+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Inconclusive	no information		RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Positive			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1	6	Male	Not reported			no data	not applicable	Inconclusive		no evidence	RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-{(EZ)-1-[(E)-3-chloroallyloxyimino]propyl}-5-[(2RS)-2-(ethylsulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one			2-[(1E)-N-{[(2E)-3-chloroprop-2-en-1-yl]oxy}propanimidoyl]-5-[2-(ethanesulfonyl)propyl]-3-hydroxycyclohex-2-en-1-one	Clethodim-Sulfon	C17H26ClNO5S	CC/C(=N\OC\C=C\Cl)C1=C(O)CC(CC(C)S(=O)(=O)CC)CC1=O	InChI=1S/C17H26ClNO5S/c1-4-14(19-24-8-6-7-18)17-15(20)10-13(11-16(17)21)9-12(3)25(22,23)5-2/h6-7,12-13,20H,4-5,8-11H2,1-3H3/b7-6+,19-14+	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No data	Acceptable	House mouse (as animal)	ICR	6	Male	Not reported			no data	not applicable	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	2-ethyl-6-[(2RS)-2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one			2-ethyl-6-[2-(ethylsulfonyl)propyl]-6,7-dihydro-1,3-benzoxazol-4(5H)-one	Not in list	C14H21NO4S	CCS(=O)(=O)C(C)CC2Cc1oc(nc1C(=O)C2)CC	InChI=1/C14H21NO4S/c1-4-13-15-14-11(16)7-10(8-12(14)19-13)6-9(3)20(17,18)5-2/h9-10H,4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1		Male	Not reported			no data	not applicable	Negative		no evidence	RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is identical to the substance	Ethametsulfuron methyl		97780-06-8	methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate	Ethametsulfuron-Methyl	C15H18N6O6S	CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is identical to the substance	Ethametsulfuron methyl		97780-06-8	methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate	Ethametsulfuron-Methyl	C15H18N6O6S	CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is identical to the substance	Ethametsulfuron methyl		97780-06-8	methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate	Ethametsulfuron-Methyl	C15H18N6O6S	CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is identical to the substance	Ethametsulfuron methyl		97780-06-8	methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate	Ethametsulfuron-Methyl	C15H18N6O6S	CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is identical to the substance	Ethametsulfuron methyl		97780-06-8	methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate	Ethametsulfuron-Methyl	C15H18N6O6S	CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is identical to the substance	Ethametsulfuron methyl		97780-06-8	methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate	Ethametsulfuron-Methyl	C15H18N6O6S	CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is identical to the substance	Ethametsulfuron methyl		97780-06-8	methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate	Ethametsulfuron-Methyl	C15H18N6O6S	CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is identical to the substance	Ethametsulfuron methyl		97780-06-8	methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate	Ethametsulfuron-Methyl	C15H18N6O6S	CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is identical to the substance	Ethametsulfuron methyl		97780-06-8	methyl 2-[[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoylsulfamoyl]benzoate	Ethametsulfuron-Methyl	C15H18N6O6S	CCOC1=NC(=NC(=N1)NC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H18N6O6S/c1-4-27-15-19-12(16-2)17-13(20-15)18-14(23)21-28(24,25)10-8-6-5-7-9(10)11(22)26-3/h5-8H,4H2,1-3H3,(H3,16,17,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, historical	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea			1-[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]urea	Not in list	C7H12N6O2	CCOc1nc(nc(NC(N)=O)n1)NC	InChI=1/C7H12N6O2/c1-3-15-7-12-5(9-2)11-6(13-7)10-4(8)14/h3H2,1-2H3,(H4,8,9,10,11,12,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, historical	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine	403-580-7	62096-63-3	6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine	Not in list	C6H11N5O	CCOC1=NC(=NC(=N1)NC)N	InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine	403-580-7	62096-63-3	6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine	Not in list	C6H11N5O	CCOC1=NC(=NC(=N1)NC)N	InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine	403-580-7	62096-63-3	6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine	Not in list	C6H11N5O	CCOC1=NC(=NC(=N1)NC)N	InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine	403-580-7	62096-63-3	6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine	Not in list	C6H11N5O	CCOC1=NC(=NC(=N1)NC)N	InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine	403-580-7	62096-63-3	6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine	Not in list	C6H11N5O	CCOC1=NC(=NC(=N1)NC)N	InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine	403-580-7	62096-63-3	6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine	Not in list	C6H11N5O	CCOC1=NC(=NC(=N1)NC)N	InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine	403-580-7	62096-63-3	6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine	Not in list	C6H11N5O	CCOC1=NC(=NC(=N1)NC)N	InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine	403-580-7	62096-63-3	6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine	Not in list	C6H11N5O	CCOC1=NC(=NC(=N1)NC)N	InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine	403-580-7	62096-63-3	6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine	Not in list	C6H11N5O	CCOC1=NC(=NC(=N1)NC)N	InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-N-methyl-1,3,5-triazine-2,4-diamine	403-580-7	62096-63-3	6-ethoxy-2-N-methyl-1,3,5-triazine-2,4-diamine	Not in list	C6H11N5O	CCOC1=NC(=NC(=N1)NC)N	InChI=1S/C6H11N5O/c1-3-12-6-10-4(7)9-5(8-2)11-6/h3H2,1-2H3,(H3,7,8,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-[(4-ethoxy-6-methylamino-1,3,5-triazin-2-yl)carbamoylsulfamoyl] benzoic acid			2-({[4-ethoxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoic acid	Not in list	C14H16N6O6S	CCOc2nc(nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2)NC	InChI=1/C14H16N6O6S/c1-3-26-14-18-11(15-2)16-12(19-14)17-13(23)20-27(24,25)9-7-5-4-6-8(9)10(21)22/h4-7H,3H2,1-2H3,(H,21,22)(H3,15,16,17,18,19,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate			methyl 2-({[4-hydroxy-6-(methylamino)-1,3,5-triazin-2-yl]carbamoyl}sulfamoyl)benzoate	Not in list	C13H14N6O6S	CNc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C13H14N6O6S/c1-14-10-15-11(17-12(21)16-10)18-13(22)19-26(23,24)8-6-4-3-5-7(8)9(20)25-2/h3-6H,1-2H3,(H4,14,15,16,17,18,19,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl} benzoic acid			2-{[(4-amino-6-ethoxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoic acid	Not in list	C13H14N6O6S	CCOc2nc(N)nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)O)n2	InChI=1/C13H14N6O6S/c1-2-25-13-16-10(14)15-11(18-13)17-12(22)19-26(23,24)8-6-4-3-5-7(8)9(20)21/h3-6H,2H2,1H3,(H,20,21)(H4,14,15,16,17,18,19,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	20	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	2-sulfamoylbenzoic acid	211-174-4	632-24-6	2-sulfamoylbenzoic acid	Not in list	C7H7NO4S	C1=CC=C(C(=C1)C(=O)O)S(=O)(=O)N	InChI=1S/C7H7NO4S/c8-13(11,12)6-4-2-1-3-5(6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	20	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl] sulfamoyl}benzoate			methyl 2-{[(4-amino-6-hydroxy-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}benzoate	Not in list	C12H12N6O6S	Nc2nc(NC(=O)NS(=O)(=O)c1ccccc1C(=O)OC)nc(O)n2	InChI=1/C12H12N6O6S/c1-24-8(19)6-4-2-3-5-7(6)25(22,23)18-12(21)17-10-14-9(13)15-11(20)16-10/h2-5H,1H3,(H5,13,14,15,16,17,18,20,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 2)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 4)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 4)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	Not reported	24.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 4)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethametsulfuron methyl		97780-06-8	single chemical entity	Component is a metabolite of the substance	6-ethoxy-1,3,5-triazine-2,4-diamine		2827-44-3	6-ethoxy-1,3,5-triazine-2,4-diamine	Not in list	C5H9N5O	CCOC1=NC(=NC(=N1)N)N	InChI=1S/C5H9N5O/c1-2-11-5-9-3(6)8-4(7)10-5/h2H2,1H3,(H4,6,7,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	Not reported	48.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: The United Kingdom	Ethametsulfuron methyl (Addendum 4)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ethametsulfuron (evaluated variant ethametsulfuron-methyl)	21Jul2014	2014	doi:10.2903/j.efsa.2014.3787
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	30.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	18.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	6.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	6.0000000000	h	yes	not applicable	Positive		indirect evidence-systemic toxicity	RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	72.0000000000	h	yes	not applicable	Positive			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Ethoprophos	236-152-1	13194-48-4	single chemical entity	Component is identical to the substance	Ethoprophos	236-152-1	13194-48-4	O-ethyl S,S-dipropyl dithiophosphate	Ethoprophos	C8H19O2PS2	O=P(SCCC)(OCC)SCCC	InChI=1S/C8H19O2PS2/c1-4-7-12-11(9,10-6-3)13-8-5-2/h4-8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	24	Male	oral: gavage	48.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Ethoprophos	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos	28Apr2006	2006	doi:10.2903/j.efsa.2006.66r
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Positive			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Positive			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar	6	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar	6	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar	6	Male/Female	oral: gavage	6.0000000000	h	yes	not applicable	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar		Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar		Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar		Male/Female	oral: gavage	6.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Wistar	10	Male/Female	oral: gavage	6.0000000000	h	yes	not applicable	Positive			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Wistar	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Positive			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Sprague-Dawley		Female	Not reported			yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Sprague-Dawley		Female	Not reported			yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar	3	Female	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Dithianon	222-098-6	3347-22-6	single chemical entity	Component is identical to the substance	Dithianon	222-098-6	3347-22-6	5,10-dioxo-5,10-dihydronaphtho[2,3-b][1,4]dithiine-2,3-dicarbonitrile	Dithianon	C14H4N2O2S2	O=C1C2=C(SC(=C(S2)C#N)C#N)C(=O)c3ccccc13	InChI=1/C14H4N2O2S2/c15-5-9-10(6-16)20-14-12(18)8-4-2-1-3-7(8)11(17)13(14)19-9/h1-4H	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar	3	Female	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Dithianon (Additional Report to DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dithianon	25Nov2010	2010	doi:10.2903/j.efsa.2010.1904
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA1978			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA1978			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is identical to the substance	Chlorthal-dimethyl	217-464-7	1861-32-1	Dimethyl 2,3,5,6-tetrachlorobenzene-1,4-dicarboxylate	Chlorthal-dimethyl	C10H6Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)OC)Cl)Cl	InChI=1S/C10H6Cl4O4/c1-17-9(15)3-5(11)7(13)4(10(16)18-2)8(14)6(3)12/h1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male	oral: gavage			yes	not applicable	Positive			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	with	Negative			RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	7	Male/Female	Not reported	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	7	Male/Female	Not reported	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	2,3,5,6-tetrachloroterephthalic acid		2136-79-0	2,3,5,6-tetrachloroterephthalic acid	Not in list	C8H2Cl4O4	C1(=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl)C(=O)O	InChI=1S/C8H2Cl4O4/c9-3-1(7(13)14)4(10)6(12)2(5(3)11)8(15)16/h(H,13,14)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	7	Male/Female	Not reported	48.0000000000	h	yes	not applicable	Positive		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Greece	Chlorthal-dimethyl	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid		887-54-7	2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid	Not in list	C9H4Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl	InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Greece	Chlorthal-dimethyl (Addendum 1 to annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid		887-54-7	2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid	Not in list	C9H4Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl	InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Greece	Chlorthal-dimethyl (Addendum 1 to annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid		887-54-7	2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid	Not in list	C9H4Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl	InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Greece	Chlorthal-dimethyl (Addendum 1 to annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid		887-54-7	2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid	Not in list	C9H4Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl	InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Greece	Chlorthal-dimethyl (Addendum 1 to annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid		887-54-7	2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid	Not in list	C9H4Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl	InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Greece	Chlorthal-dimethyl (Addendum 1 to annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid		887-54-7	2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid	Not in list	C9H4Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl	InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Greece	Chlorthal-dimethyl (Addendum 1 to annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid		887-54-7	2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid	Not in list	C9H4Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl	InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Greece	Chlorthal-dimethyl (Addendum 1 to annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid		887-54-7	2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid	Not in list	C9H4Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl	InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Greece	Chlorthal-dimethyl (Addendum 1 to annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid		887-54-7	2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid	Not in list	C9H4Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl	InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Greece	Chlorthal-dimethyl (Addendum 1 to annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Chlorthal-dimethyl	217-464-7	1861-32-1	single chemical entity	Component is a metabolite of the substance	4-carbomethoxy-2,3,5,6-tetrachlorobenzoic acid		887-54-7	2,3,5,6-tetrachloro-4-methoxycarbonylbenzoic acid	Not in list	C9H4Cl4O4	COC(=O)C1=C(C(=C(C(=C1Cl)Cl)C(=O)O)Cl)Cl	InChI=1S/C9H4Cl4O4/c1-17-9(16)3-6(12)4(10)2(8(14)15)5(11)7(3)13/h1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Greece	Chlorthal-dimethyl (Addendum 1 to annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the focussed peer review of the pesticide risk assessment of the active substance chlorthal-dimethyl	25Sep2009	2009	doi:10.2903/j.efsa.2009.202r
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Schizosaccharomyces pombe (as organism)				Not reported			yes	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Schizosaccharomyces pombe (as organism)				Not reported			yes	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is identical to the substance	Benalaxyl-M		98243-83-5	methyl N-(2,6-dimethylphenyl)-N-(phenylacetyl)-D-alaninate	Benalaxyl-M	C20H23NO3	C[C@@H](N(C(=O)Cc1ccccc1)c2c(C)cccc2C)C(=O)OC	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3/t16-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Not reported	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is part of a group assessment	Benalaxyl	275-728-7	71626-11-4	Methyl 2-(2,6-dimethyl-N-(2-phenylacetyl)anilino)propanoate	Benalaxyl	C20H23NO3	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)CC2=CC=CC=C2	InChI=1S/C20H23NO3/c1-14-9-8-10-15(2)19(14)21(16(3)20(23)24-4)18(22)13-17-11-6-5-7-12-17/h5-12,16H,13H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Not reported	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Benalaxyl-M	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	20	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is identical to the substance	Cyantraniliprole		736994-63-1	3-bromo-1-(3-chloro-2-pyridyl)-4'-cyano-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Not in list	C19H14BrClN6O2	CC1=CC(=CC(=C1NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br)C(=O)NC)C#N	InChI=1S/C19H14BrClN6O2/c1-10-6-11(9-22)7-12(18(28)23-2)16(10)25-19(29)14-8-15(20)26-27(14)17-13(21)4-3-5-24-17/h3-8H,1-2H3,(H,23,28)(H,25,29)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	20	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid			4-({[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]carbonyl}amino)-3-methyl-5-(methylcarbamoyl)benzoic acid	Not in list	C19H15BrClN5O4	O=C(O)c3cc(C)c(NC(=O)c2cc(Br)nn2c1ncccc1Cl)c(c3)C(=O)NC	InChI=1/C19H15BrClN5O4/c1-9-6-10(19(29)30)7-11(17(27)22-2)15(9)24-18(28)13-8-14(20)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)(H,29,30)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-8-methyl-4-oxo-1,4-dihydroquinazoline-6-carboxylic acid	Not in list	C18H11BrClN5O3	O=C(O)c1cc2C(=O)N=C(Nc2c(C)c1)c4cc(Br)nn4c3ncccc3Cl	InChI=1/C18H11BrClN5O3/c1-8-5-9(18(27)28)6-10-14(8)22-15(23-17(10)26)12-7-13(19)24-25(12)16-11(20)3-2-4-21-16/h2-7H,1H3,(H,27,28)(H,22,23,26)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile			6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile	Not in list	C14H8ClN3O	Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile			6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile	Not in list	C14H8ClN3O	Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile			6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile	Not in list	C14H8ClN3O	Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile			6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile	Not in list	C14H8ClN3O	Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile			6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile	Not in list	C14H8ClN3O	Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile			6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile	Not in list	C14H8ClN3O	Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile			6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile	Not in list	C14H8ClN3O	Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile			6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile	Not in list	C14H8ClN3O	Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile			6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile	Not in list	C14H8ClN3O	Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile			6-chloro-4-methyl-11-oxo-11H-pyrido[2,1-b]quinazoline-2-carbonitrile	Not in list	C14H8ClN3O	Cc3cc(C#N)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C14H8ClN3O/c1-8-5-9(7-16)6-10-12(8)17-13-11(15)3-2-4-18(13)14(10)19/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	fibroblast			Not reported			no data	without	Positive			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA94			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA94			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA92			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA92			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	fibroblast			Not reported			no data	without	Inconclusive			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA92			Not reported			no data	with	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA94			Not reported			no data	with	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1530			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one	Not in list	C15H21NO3	Oc1ccc(cc1OC)C(=O)CCN2CCCCC2	InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1530			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one	Not in list	C15H21NO3	Oc1ccc(cc1OC)C(=O)CCN2CCCCC2	InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1531			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one	Not in list	C14H19NO3	O=C(CCN1CCCC1)c2ccc(O)c(OC)c2	InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1964			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1532			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one	Not in list	C14H19NO3	O=C(CCN1CCCC1)c2ccc(O)c(OC)c2	InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1531			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1964			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one	Not in list	C14H19NO3	O=C(CCN1CCCC1)c2ccc(O)c(OC)c2	InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1532			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one	Not in list	C15H21NO3	Oc1ccc(cc1OC)C(=O)CCN2CCCCC2	InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1532			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one	Not in list	C15H21NO3	Oc1ccc(cc1OC)C(=O)CCN2CCCCC2	InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1530			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one	Not in list	C15H21NO3	Oc1ccc(cc1OC)C(=O)CCN2CCCCC2	InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1532			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one	Not in list	C15H21NO3	Oc1ccc(cc1OC)C(=O)CCN2CCCCC2	InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1964			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one	Not in list	C15H21NO3	Oc1ccc(cc1OC)C(=O)CCN2CCCCC2	InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1531			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one	Not in list	C14H19NO3	O=C(CCN1CCCC1)c2ccc(O)c(OC)c2	InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1530			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1530			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one	Not in list	C14H19NO3	O=C(CCN1CCCC1)c2ccc(O)c(OC)c2	InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1531			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one	Not in list	C14H19NO3	O=C(CCN1CCCC1)c2ccc(O)c(OC)c2	InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1530			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-piperidyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(piperidin-1-yl)propan-1-one	Not in list	C15H21NO3	Oc1ccc(cc1OC)C(=O)CCN2CCCCC2	InChI=1/C15H21NO3/c1-19-15-11-12(5-6-14(15)18)13(17)7-10-16-8-3-2-4-9-16/h5-6,11,18H,2-4,7-10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1964			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one	Not in list	C14H19NO3	O=C(CCN1CCCC1)c2ccc(O)c(OC)c2	InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1532			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is a metabolite of the substance	3-pyrrolidinyl-1-(3’-methoxy-4’-hydroxyphenyl)-1-propanone			1-(4-hydroxy-3-methoxyphenyl)-3-(pyrrolidin-1-yl)propan-1-one	Not in list	C14H19NO3	O=C(CCN1CCCC1)c2ccc(O)c(OC)c2	InChI=1S/C14H19NO3/c1-18-14-10-11(4-5-13(14)17)12(16)6-9-15-7-2-3-8-15/h4-5,10,17H,2-3,6-9H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1964			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1964			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1531			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1531			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1532			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Positive			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	embryo cells			Not reported			yes	without	Positive			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	embryo cells			Not reported			yes	with	Positive			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	small colonies		RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	leukemia cells (HL-60)			Not reported			no data	without	Positive			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ddy mouse	6	Male	Not reported	18.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ddy mouse	6	Male	Not reported	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	SwissWebster		Male	intraperitoneal			no data	not applicable	Positive		no evidence	RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	SwissWebster		Male	oral: gavage			no data	not applicable	Positive		no evidence	RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	5	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CF-1	8	Male	intraperitoneal	30.0000000000	h	yes	not applicable	Positive		no evidence	RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CF-1	8	Male	intraperitoneal	48.0000000000	h	yes	not applicable	Positive		no evidence	RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CF-1	8	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Positive		no evidence	RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Female	oral: gavage	30.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Female	oral: gavage	48.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Female	oral: gavage	6.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Female	oral: gavage	48.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Female	oral: gavage	2.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Female	oral: gavage	2.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Female	oral: gavage	24.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Female	oral: gavage	30.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Female	oral: gavage	6.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Female	oral: gavage	24.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		4	Male	oral: feed	58.0000000000	D	yes	not applicable	Ambiguous			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		4	Male	oral: feed	58.0000000000	D	yes	not applicable	Ambiguous			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Rat (as animal)	Wistar		Male	oral: gavage	10.0000000000	D	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No data	Acceptable	Rat (as animal)	Wistar		Male	oral: gavage	10.0000000000	D	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Human (as organism)			No data	oral: capsule	22.0000000000	D	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Human (as organism)			No data	oral: capsule	22.0000000000	D	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Human (as organism)			No data	oral: capsule	8.0000000000	D	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Human (as organism)			No data	oral: capsule	8.0000000000	D	no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Eugenol	202-589-1	97-53-0	single chemical entity	Component is identical to the substance	Eugenol	202-589-1	97-53-0	2-Methoxy-4-prop-2-enylphenol	Not in list	C10H12O2	COC1=C(C=CC(=C1)CC=C)O	InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal			no data	not applicable	Negative			RMS: The United Kingdom	Eugenol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance eugenol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2914
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is identical to the substance	Chlorantraniliprole		500008-45-7	3-Bromo-4'-chloro-1-(3 chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide	Chlorantraniliprole (DPX E-2Y45)	C18H14BrCl2N5O2	CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br	InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(20)7-11(17(27)22-2)15(9)24-18(28)13-8-14(19)25-26(13)16-12(21)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C18H12BrCl2N5O	Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O	InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C18H12BrCl2N5O	Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O	InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C18H12BrCl2N5O	Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O	InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C18H12BrCl2N5O	Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O	InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C18H12BrCl2N5O	Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O	InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C18H12BrCl2N5O	Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O	InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C18H12BrCl2N5O	Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O	InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C18H12BrCl2N5O	Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O	InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C18H12BrCl2N5O	Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O	InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-[3-bromo-1-(3-chloropyridin-2-yl)-1Hpyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-[3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl]-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C18H12BrCl2N5O	Cc4cc(Cl)cc3c4N=C(c2cc(Br)nn2c1ncccc1Cl)N(C)C3=O	InChI=1/C18H12BrCl2N5O/c1-9-6-10(20)7-11-15(9)23-17(25(2)18(11)27)13-8-14(19)24-26(13)16-12(21)4-3-5-22-16/h3-8H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C13H10BrClN4O	Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C	InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C13H10BrClN4O	Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C	InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C13H10BrClN4O	Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C	InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C13H10BrClN4O	Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C	InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C13H10BrClN4O	Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C	InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C13H10BrClN4O	Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C	InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C13H10BrClN4O	Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C	InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C13H10BrClN4O	Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C	InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C13H10BrClN4O	Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C	InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one			2-(3-bromo-1H-pyrazol-5-yl)-6-chloro-3,8-dimethylquinazolin-4(3H)-one	Not in list	C13H10BrClN4O	Brc1cc(nn1)C2=Nc3c(C)cc(Cl)cc3C(=O)N2C	InChI=1/C13H10BrClN4O/c1-6-3-7(15)4-8-11(6)16-12(19(2)13(8)20)9-5-10(14)18-17-9/h3-5H,1-2H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one			2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one	Not in list	C13H8Cl2N2O	Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one			2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one	Not in list	C13H8Cl2N2O	Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one			2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one	Not in list	C13H8Cl2N2O	Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one			2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one	Not in list	C13H8Cl2N2O	Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one			2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one	Not in list	C13H8Cl2N2O	Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one			2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one	Not in list	C13H8Cl2N2O	Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one			2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one	Not in list	C13H8Cl2N2O	Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one			2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one	Not in list	C13H8Cl2N2O	Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one			2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one	Not in list	C13H8Cl2N2O	Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one			2,6-dichloro-4-methyl-11H-pyrido[2,1-b]quinazolin-11-one	Not in list	C13H8Cl2N2O	Cc3cc(Cl)cc2c3N=C1C(Cl)=CC=CN1C2=O	InChI=1/C13H8Cl2N2O/c1-7-5-8(14)6-9-11(7)16-12-10(15)3-2-4-17(12)13(9)18/h2-6H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Chlorantraniliprole		500008-45-7	single chemical entity	Component is a metabolite of the substance	3-bromo-N-methyl-1H-pyrazole-5-carboxamide			3-bromo-N-methyl-1H-pyrazole-5-carboxamide	Not in list	C5H6BrN3O	O=C(NC)c1cc(Br)nn1	InChI=1/C5H6BrN3O/c1-7-5(10)3-2-4(6)9-8-3/h2H,1H3,(H,7,10)(H,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Chlorantraniliprole	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorantraniliprole.	06Jun2013	2013	doi:10.2903/j.efsa.2013.3143
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA1978			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA1978			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Inconclusive		indirect evidence-systemic toxicity	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Inconclusive		indirect evidence-systemic toxicity	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male	oral: unspecified	96.0000000000	h	yes, concurrent vehicle	not applicable	Inconclusive		indirect evidence-systemic toxicity	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	4	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	4	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	4	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)				Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)				Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	18.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	42.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	oral: unspecified	24.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	intraperitoneal	48.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	mixture or formulation	Component is the active ingredient of the mixture or formulation	Carbosulfan formulation (Marshal 25CS)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Not reported	6	Male/Female	intraperitoneal	12.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	mixture or formulation	Component is the active ingredient of the mixture or formulation	Carbosulfan formulation (Marshal 25CS)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Not reported	6	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	mixture or formulation	Component is the active ingredient of the mixture or formulation	Carbosulfan formulation (Marshal 25CS)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Not reported	6	Male/Female	intraperitoneal	6.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	CD-1	12	Male	oral: gavage			yes	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)				Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)				Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)				Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)				Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Ambiguous			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Ambiguous			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes	with	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes	with	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		Male	intraperitoneal			yes, concurrent vehicle	not applicable	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	4	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	4	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	4	No data	oral: unspecified	24.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		Male	intraperitoneal			yes, concurrent vehicle	not applicable	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	4	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	4	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	4	No data	oral: unspecified	24.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	SwissWebster	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	SwissWebster	5	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	SwissWebster	5	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	SwissWebster	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	6.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	6.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	6.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	6.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	SwissWebster	5	Male	oral: gavage	48.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	SwissWebster	5	Male	oral: gavage	24.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	SwissWebster	5	Male	oral: gavage	48.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	SwissWebster	5	Male	oral: gavage	24.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed	22.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed	22.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	Not reported	24.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	Not reported	24.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is a metabolite of the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Carbosulfan	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbofuran	216-353-0	1563-66-2	single chemical entity	Component is identical to the substance	Carbofuran	216-353-0	1563-66-2	2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate	Carbofuran	C12H15NO3	CNC(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Carbofuran (Annex B)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Carbofuran	10Jul2009	2009	doi:10.2903/j.efsa.2009.310r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Positive			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Positive			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Positive			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Positive			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI		Male	oral: gavage			yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Chloridazon (Final Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Chloridazon (Final Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon (Final Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is identical to the substance	Chloridazon	216-920-2	1698-60-8	5-amino-4-chloro-2-phenylpyridazin-3(2H)-one	Chloridazon	C10H8ClN3O	NC1=C(Cl)C(=O)N(N=C1)c2ccccc2	InChI=1/C10H8ClN3O/c11-9-8(12)6-13-14(10(9)15)7-4-2-1-3-5-7/h1-6H,12H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Chloridazon (Final Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-3(2H)-pyridazinone		6339-19-1	4-amino-5-chloro-1H-pyridazin-6-one	Not in list	C4H4ClN3O	C1=NNC(=O)C(=C1N)Cl	InChI=1S/C4H4ClN3O/c5-3-2(6)1-7-8-4(3)9/h1H,(H3,6,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar		Male	oral: unspecified	20.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chloridazon	216-920-2	1698-60-8	single chemical entity	Component is a metabolite of the substance	5-amino-4-chloro-2-methyl-3(2H)-pyridazinone	605-639-4	17254-80-7	5-amino-4-chloro-2-methylpyridazin-3-one	Not in list	C5H6ClN3O	CN1C(=O)C(=C(C=N1)N)Cl	InChI=1S/C5H6ClN3O/c1-9-5(10)4(6)3(7)2-8-9/h2H,7H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar		Male	oral: unspecified	44.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Chloridazon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chloridazon	13Aug2007	2007	doi:10.2903/j.efsa.2007.108r
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is identical to the substance	Chromafenozide		143807-66-3	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-5-methyl-3,4-dihydro-2H-chromene-6-carbohydrazide	Chromafenozide	C24H30N2O3	CC1=CC(=CC(=C1)C(=O)N(C(C)(C)C)NC(=O)C2=C(C3=C(C=C2)OCCC3)C)C	InChI=1S/C24H30N2O3/c1-15-12-16(2)14-18(13-15)23(28)26(24(4,5)6)25-22(27)20-9-10-21-19(17(20)3)8-7-11-29-21/h9-10,12-14H,7-8,11H2,1-6H3,(H,25,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N‟-tert-butyl-N‟-(5-methyl-6-chromancarbonyl)-5-methyl-6-chroman-carbohydrazide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide			N'-tert-butyl-N'-(3,5-dimethylbenzoyl)-4-hydroxy-5-methylchromane-6-carbohydrazide	Not in list	C24H30N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H30N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)18-7-8-20-21(16(18)3)19(27)9-10-30-20/h7-8,11-13,19,27H,9-10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide			N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide	Not in list	C24H28N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C	InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide			N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide	Not in list	C24H28N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C	InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide			N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide	Not in list	C24H28N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C	InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide			N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide	Not in list	C24H28N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C	InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide			N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide	Not in list	C24H28N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C	InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide			N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide	Not in list	C24H28N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C	InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide			N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide	Not in list	C24H28N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C	InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide			N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide	Not in list	C24H28N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C	InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide			N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide	Not in list	C24H28N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C	InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide			N'-tert-butyl-N'-[(3,5-dimethylphenyl)carbonyl]-5-methyl-2-oxo-3,4-dihydro-2H-chromene-6-carbohydrazide	Not in list	C24H28N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c3ccc2OC(=O)CCc2c3C)C(C)(C)C	InChI=1/C24H28N2O4/c1-14-11-15(2)13-17(12-14)23(29)26(24(4,5)6)25-22(28)19-7-9-20-18(16(19)3)8-10-21(27)30-20/h7,9,11-13H,8,10H2,1-6H3,(H,25,28)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid			3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid	Not in list	C24H28N2O6	O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid			3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid	Not in list	C24H28N2O6	O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid			3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid	Not in list	C24H28N2O6	O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid			3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid	Not in list	C24H28N2O6	O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid			3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid	Not in list	C24H28N2O6	O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid			3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid	Not in list	C24H28N2O6	O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid			3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid	Not in list	C24H28N2O6	O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid			3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid	Not in list	C24H28N2O6	O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid			3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid	Not in list	C24H28N2O6	O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chromafenozide		143807-66-3	single chemical entity	Component is a metabolite of the substance	3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid			3-({1-tert-butyl-2-[(4-hydroxy-5-methyl-3,4-dihydro-2H-chromen-6-yl)carbonyl]hydrazinyl}carbonyl)-5-methylbenzoic acid	Not in list	C24H28N2O6	O=C(O)c1cc(C)cc(c1)C(=O)N(NC(=O)c3ccc2OCCC(O)c2c3C)C(C)(C)C	InChI=1/C24H28N2O6/c1-13-10-15(12-16(11-13)23(30)31)22(29)26(24(3,4)5)25-21(28)17-6-7-19-20(14(17)2)18(27)8-9-32-19/h6-7,10-12,18,27H,8-9H2,1-5H3,(H,25,28)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Chromafenozide	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chromafenozide.	13Dec2013	2013	doi:10.2903/j.efsa.2013.3461
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent no treatment	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent no treatment	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	K12			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Klebsiella pneumoniae (as organism)	Not reported			Not reported			yes, concurrent no treatment	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Citrobacter (as organism)	Not reported			Not reported			yes, concurrent no treatment	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	PQ37			Not reported			no data	without	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	PQ37			Not reported			no data	with	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss		Male/Female	Not reported			yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	NMRI	40	Male	oral: gavage			yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	Swiss		Male	oral: gavage			no data	not applicable	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	Swiss		Male	intraperitoneal			no data	not applicable	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	Not reported			no data	not applicable	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Chlormequat chloride	213-666-4	999-81-5	single chemical entity	Component is identical to the substance	Chlormequat chloride	213-666-4	999-81-5	2-Chloroethyl(trimethyl)azanium;chloride	Chlormequat	C5H13Cl2N	C[N+](C)(C)CCCl.[Cl-]	InChI=1S/C5H13ClN.ClH/c1-7(2,3)5-4-6;/h4-5H2,1-3H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	Not reported			no data	not applicable	Negative			RMS: The United Kingdom	Chlormequat-chloride	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance chlormequat (considered variant chlormequat chloride)	25Feb2009	2009	doi:10.2903/j.efsa.2009.179r
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	small colonies		RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is identical to the substance	Cyflumetofen		400882-07-7	2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate	Cyflumetofen	C24H24F3NO4	CC(C)(C)C1=CC=C(C=C1)C(C#N)(C(=O)C2=CC=CC=C2C(F)(F)F)C(=O)OCCOC	InChI=1S/C24H24F3NO4/c1-22(2,3)16-9-11-17(12-10-16)23(15-28,21(30)32-14-13-31-4)20(29)18-7-5-6-8-19(18)24(25,26)27/h5-12H,13-14H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	small colonies		RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	large colonies		RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	Alpha,alpha,alpha-trifluoro-o-toluic acid	207-093-9	433-97-6	2-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	C1=CC=C(C(=C1)C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O2/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Cyflumetofen		400882-07-7	single chemical entity	Component is a metabolite of the substance	2-(Trifluoromethyl) benzamide	206-637-2	360-64-5	2-(trifluoromethyl)benzamide	Not in list	C8H6F3NO	C1=CC=C(C(=C1)C(=O)N)C(F)(F)F	InChI=1S/C8H6F3NO/c9-8(10,11)6-4-2-1-3-5(6)7(12)13/h1-4H,(H2,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Cyflumetofen (OK-5101)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyflumetofen	23Jan2012	2012	doi:10.2903/j.efsa.2012.2504
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	5	Male	intraperitoneal	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	5	Male	intraperitoneal	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is identical to the substance	Carfentrazone-ethyl	603-291-8	128639-02-1	ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate	Carfentrazone-ethyl	C15H14Cl2F3N3O3	CCOC(=O)C(CC1=CC(=C(C=C1Cl)F)N2C(=O)N(C(=N2)C)C(F)F)Cl	InChI=1S/C15H14Cl2F3N3O3/c1-3-26-13(24)10(17)4-8-5-12(11(18)6-9(8)16)23-15(25)22(14(19)20)7(2)21-23/h5-6,10,14H,3-4H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	72.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid	603-289-7	128621-72-7	2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid	Not in list	C13H10Cl2F3N3O3	CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F	InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid	603-289-7	128621-72-7	2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid	Not in list	C13H10Cl2F3N3O3	CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F	InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid	603-289-7	128621-72-7	2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid	Not in list	C13H10Cl2F3N3O3	CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F	InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid	603-289-7	128621-72-7	2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid	Not in list	C13H10Cl2F3N3O3	CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F	InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid	603-289-7	128621-72-7	2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid	Not in list	C13H10Cl2F3N3O3	CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F	InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid	603-289-7	128621-72-7	2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid	Not in list	C13H10Cl2F3N3O3	CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F	InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid	603-289-7	128621-72-7	2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid	Not in list	C13H10Cl2F3N3O3	CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F	InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid	603-289-7	128621-72-7	2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid	Not in list	C13H10Cl2F3N3O3	CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F	InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid	603-289-7	128621-72-7	2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid	Not in list	C13H10Cl2F3N3O3	CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F	InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propionic acid	603-289-7	128621-72-7	2-chloro-3-{2-chloro-5-[4- (difluoromethyl)-3-methyl-5-oxo- 1,2,4-triazol-1-yl]-4- fluorophenyl}propanoic acid	Not in list	C13H10Cl2F3N3O3	CC1=NN(C(=O)N1C(F)F)C2=C(C=C(C(=C2)CC(C(=O)O)Cl)Cl)F	InChI=1S/C13H10Cl2F3N3O3/c1-5-19-21(13(24)20(5)12(17)18)10-3-6(2-8(15)11(22)23)7(14)4-9(10)16/h3-4,8,12H,2H2,1H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid			2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3O3	O=C(O)c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C11H7ClF3N3O3/c1-4-16-18(11(21)17(4)10(14)15)8-2-5(9(19)20)6(12)3-7(8)13/h2-3,10H,1H3,(H,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C13H11ClF3N3O3	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h4-5,12H,2-3H2,1H3,(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}-2-sulfopropanoic acid	Not in list	C13H11ClF3N3O6S	O=C(O)C(Cc1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F)S(=O)(=O)O	InChI=1/C13H11ClF3N3O6S/c1-5-18-20(13(23)19(5)12(16)17)9-2-6(7(14)4-8(9)15)3-10(11(21)22)27(24,25)26/h2,4,10,12H,3H2,1H3,(H,21,22)(H,24,25,26)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Not reported	10	Male/Female	Not reported	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorobenzoic acid		380885-65-4	2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-1,2,4-triazol-1-yl]-4-fluorobenzoic acid	Not in list	C11H7ClF3N3O4	C1=C(C(=CC(=C1N2C(=O)N(C(=N2)CO)C(F)F)F)Cl)C(=O)O	InChI=1S/C11H7ClF3N3O4/c12-5-2-6(13)7(1-4(5)9(20)21)18-11(22)17(10(14)15)8(3-19)16-18/h1-2,10,19H,3H2,(H,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Not reported	10	Male/Female	Not reported	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	2-(4-Chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one		97986-18-0	2-(4-chloro-2-fluoro-5-methoxyphenyl)-4-(difluoromethyl)-5-methyl-1,2,4-triazol-3-one	Not in list	C11H9ClF3N3O2	CC1=NN(C(=O)N1C(F)F)C2=CC(=C(C=C2F)Cl)OC	InChI=1S/C11H9ClF3N3O2/c1-5-16-18(11(19)17(5)10(14)15)8-4-9(20-2)6(12)3-7(8)13/h3-4,10H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	1-(5-Carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid			1-(5-carboxy-4-chloro-2-fluorophenyl)-4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C11H5ClF3N3O5	O=C(O)c1cc(c(F)cc1Cl)N2N=C(N(C2=O)C(F)F)C(=O)O	InChI=1/C11H5ClF3N3O5/c12-4-2-5(13)6(1-3(4)8(19)20)18-11(23)17(10(14)15)7(16-18)9(21)22/h1-2,10H,(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	Carfentrazone ethyl lysimeter percolate				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	Carfentrazone ethyl lysimeter percolate				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	Carfentrazone ethyl lysimeter percolate				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	Carfentrazone ethyl lysimeter percolate				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	Carfentrazone ethyl lysimeter percolate				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	Carfentrazone ethyl lysimeter percolate				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	Carfentrazone ethyl lysimeter percolate				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	Carfentrazone ethyl lysimeter percolate				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	Carfentrazone ethyl lysimeter percolate				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	Carfentrazone ethyl lysimeter percolate				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	30	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	30	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	30	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	20	Male/Female	Not reported	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	20	Male/Female	Not reported	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	20	Male/Female	Not reported	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	16.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	12	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	12	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	12	Male/Female	intraperitoneal	30.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Not reported	6	Female	oral: feed	7.0000000000	D	yes	not applicable	Ambiguous			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	54	Male	Not reported	12.0000000000	h	yes	not applicable	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is identical to the substance	Diuron	206-354-4	330-54-1	3-(3,4-dichlorophenyl)-1,1-dimethylurea	Diuron	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=C(C=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-6-3-4-7(10)8(11)5-6/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	54	Male	Not reported	6.0000000000	h	yes	not applicable	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	Monuron	205-766-1	150-68-5	3-(4-chlorophenyl)-1,1-dimethylurea	Monuron	C9H11ClN2O	CN(C)C(=O)NC1=CC=C(C=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	Monuron	205-766-1	150-68-5	3-(4-chlorophenyl)-1,1-dimethylurea	Monuron	C9H11ClN2O	CN(C)C(=O)NC1=CC=C(C=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	Monuron	205-766-1	150-68-5	3-(4-chlorophenyl)-1,1-dimethylurea	Monuron	C9H11ClN2O	CN(C)C(=O)NC1=CC=C(C=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	Monuron	205-766-1	150-68-5	3-(4-chlorophenyl)-1,1-dimethylurea	Monuron	C9H11ClN2O	CN(C)C(=O)NC1=CC=C(C=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	Monuron	205-766-1	150-68-5	3-(4-chlorophenyl)-1,1-dimethylurea	Monuron	C9H11ClN2O	CN(C)C(=O)NC1=CC=C(C=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	Monuron	205-766-1	150-68-5	3-(4-chlorophenyl)-1,1-dimethylurea	Monuron	C9H11ClN2O	CN(C)C(=O)NC1=CC=C(C=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	Monuron	205-766-1	150-68-5	3-(4-chlorophenyl)-1,1-dimethylurea	Monuron	C9H11ClN2O	CN(C)C(=O)NC1=CC=C(C=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	Monuron	205-766-1	150-68-5	3-(4-chlorophenyl)-1,1-dimethylurea	Monuron	C9H11ClN2O	CN(C)C(=O)NC1=CC=C(C=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	3-(3-chlorophenyl)-1,1-dimethyl urea		587-34-8	3-(3-chlorophenyl)-1,1-dimethylurea	Not in list	C9H11ClN2O	CN(C)C(=O)NC1=CC(=CC=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	3-(3-chlorophenyl)-1,1-dimethyl urea		587-34-8	3-(3-chlorophenyl)-1,1-dimethylurea	Not in list	C9H11ClN2O	CN(C)C(=O)NC1=CC(=CC=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	3-(3-chlorophenyl)-1,1-dimethyl urea		587-34-8	3-(3-chlorophenyl)-1,1-dimethylurea	Not in list	C9H11ClN2O	CN(C)C(=O)NC1=CC(=CC=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	3-(3-chlorophenyl)-1,1-dimethyl urea		587-34-8	3-(3-chlorophenyl)-1,1-dimethylurea	Not in list	C9H11ClN2O	CN(C)C(=O)NC1=CC(=CC=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	3-(3-chlorophenyl)-1,1-dimethyl urea		587-34-8	3-(3-chlorophenyl)-1,1-dimethylurea	Not in list	C9H11ClN2O	CN(C)C(=O)NC1=CC(=CC=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	3-(3-chlorophenyl)-1,1-dimethyl urea		587-34-8	3-(3-chlorophenyl)-1,1-dimethylurea	Not in list	C9H11ClN2O	CN(C)C(=O)NC1=CC(=CC=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	3-(3-chlorophenyl)-1,1-dimethyl urea		587-34-8	3-(3-chlorophenyl)-1,1-dimethylurea	Not in list	C9H11ClN2O	CN(C)C(=O)NC1=CC(=CC=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	3-(3-chlorophenyl)-1,1-dimethyl urea		587-34-8	3-(3-chlorophenyl)-1,1-dimethylurea	Not in list	C9H11ClN2O	CN(C)C(=O)NC1=CC(=CC=C1)Cl	InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-4-7(10)6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	(3,5-dichlorophenyl)-1,1-dimethyl urea		10290-38-7	3-(3,5-dichlorophenyl)-1,1-dimethylurea	Not in list	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	(3,5-dichlorophenyl)-1,1-dimethyl urea		10290-38-7	3-(3,5-dichlorophenyl)-1,1-dimethylurea	Not in list	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	(3,5-dichlorophenyl)-1,1-dimethyl urea		10290-38-7	3-(3,5-dichlorophenyl)-1,1-dimethylurea	Not in list	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	(3,5-dichlorophenyl)-1,1-dimethyl urea		10290-38-7	3-(3,5-dichlorophenyl)-1,1-dimethylurea	Not in list	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	(3,5-dichlorophenyl)-1,1-dimethyl urea		10290-38-7	3-(3,5-dichlorophenyl)-1,1-dimethylurea	Not in list	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	(3,5-dichlorophenyl)-1,1-dimethyl urea		10290-38-7	3-(3,5-dichlorophenyl)-1,1-dimethylurea	Not in list	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	(3,5-dichlorophenyl)-1,1-dimethyl urea		10290-38-7	3-(3,5-dichlorophenyl)-1,1-dimethylurea	Not in list	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Diuron	206-354-4	330-54-1	single chemical entity	Component is a metabolite of the substance	(3,5-dichlorophenyl)-1,1-dimethyl urea		10290-38-7	3-(3,5-dichlorophenyl)-1,1-dimethylurea	Not in list	C9H10Cl2N2O	CN(C)C(=O)NC1=CC(=CC(=C1)Cl)Cl	InChI=1S/C9H10Cl2N2O/c1-13(2)9(14)12-8-4-6(10)3-7(11)5-8/h3-5H,1-2H3,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Diuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Diuron	28Jan2005	2005	doi:10.2903/j.efsa.2005.25r
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is identical to the substance	Cycloxydim		101205-02-1	2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Cycloxydim	C17H27NO3S	CCC/C(=N\OCC)C=1C(=O)CC(CC=1O)C2CCCSC2	InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethoxyimino)butyl]-3,5-dihydroxy-5-(3-thianyl)-2-cycloexene-1-one S-oxide			3-{4-[(1E)-N-ethoxybutanimidoyl]-1,3-dihydroxy-5-oxocyclohex-3-en-1-yl}-14-thian-1-one	Not in list	C17H27NO5S	O=S1CCCC(C1)C2(O)CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO5S/c1-3-6-13(18-23-4-2)16-14(19)9-17(21,10-15(16)20)12-7-5-8-24(22)11-12/h12,19,21H,3-11H2,1-2H3/b18-13+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide			2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Not in list	C17H27NO4S	O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide			2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Not in list	C17H27NO4S	O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide			2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Not in list	C17H27NO4S	O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide			2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Not in list	C17H27NO4S	O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide			2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Not in list	C17H27NO4S	O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide			2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Not in list	C17H27NO4S	O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide			2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Not in list	C17H27NO4S	O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide			2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Not in list	C17H27NO4S	O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide			2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Not in list	C17H27NO4S	O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	2-[1-(ethylimino)butyl]-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)-2-cyclohexen-1-one S-oxide			2-[(1E)-N-ethoxybutanimidoyl]-3-hydroxy-5-(1-oxidotetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one	Not in list	C17H27NO4S	O=S1CCCC(C1)C2CC(=O)C(C(\CCC)=N\OCC)=C(O)C2	InChI=1/C17H27NO4S/c1-3-6-14(18-22-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-23(21)11-12/h12-13,19H,3-11H2,1-2H3/b18-14+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM881			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM881			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Wistar		Male	oral: gavage			yes	not applicable	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid			2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid	Not in list	C11H14O6S	CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O	InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid			2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid	Not in list	C11H14O6S	CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O	InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid			2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid	Not in list	C11H14O6S	CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O	InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid			2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid	Not in list	C11H14O6S	CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O	InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid			2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid	Not in list	C11H14O6S	CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O	InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid			2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid	Not in list	C11H14O6S	CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O	InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid			2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid	Not in list	C11H14O6S	CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O	InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid			2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid	Not in list	C11H14O6S	CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O	InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid			2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid	Not in list	C11H14O6S	CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O	InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoic acid			2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoic acid	Not in list	C11H14O6S	CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C(=O)O	InChI=1/C11H14O6S/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16/h4-6,12H,1-3H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	sodium 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoate			sodium 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoate	Not in list	C11H13NaO6S	[Na+].CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C([O-])=O	InChI=1/C11H14O6S.Na/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16;/h4-6,12H,1-3H3,(H,13,14);/q;+1/p-1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	sodium 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoate			sodium 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoate	Not in list	C11H13NaO6S	[Na+].CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C([O-])=O	InChI=1/C11H14O6S.Na/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16;/h4-6,12H,1-3H3,(H,13,14);/q;+1/p-1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	sodium 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoate			sodium 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoate	Not in list	C11H13NaO6S	[Na+].CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C([O-])=O	InChI=1/C11H14O6S.Na/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16;/h4-6,12H,1-3H3,(H,13,14);/q;+1/p-1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is a metabolite of the substance	sodium 2-{2-hydroxy-5-[(methylsulfonyl)methyl]phenyl}-2-methylpropanoate			sodium 2-{2-hydroxy-5-[(methylsulfonyl)oxy]phenyl}-2-methylpropanoate	Not in list	C11H13NaO6S	[Na+].CC(C)(c1cc(ccc1O)OS(C)(=O)=O)C([O-])=O	InChI=1/C11H14O6S.Na/c1-11(2,10(13)14)8-6-7(4-5-9(8)12)17-18(3,15)16;/h4-6,12H,1-3H3,(H,13,14);/q;+1/p-1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Not reported		No data	oral: unspecified			no data	not applicable	Negative		no evidence	RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	spleen cells			Not reported			yes	without	Positive			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	K12			Not reported			no data	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	House mouse (as animal)	spleen cells			Not reported			yes	without	Positive			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	72.0000000000	h	no	not applicable	Negative		no evidence	RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	no	not applicable	Negative		no evidence	RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	no	not applicable	Negative		no evidence	RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss		Male/Female	Not reported	30.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss		Male/Female	Not reported	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is identical to the substance	Chlorpyrifos	220-864-4	2921-88-2	O,O-diethyl O-(3,5,6-trichloropyridin-2-yl) thiophosphate	Chlorpyrifos	C9H11Cl3NO3PS	S=P(OC1=NC(=C(C=C1Cl)Cl)Cl)(OCC)OCC	InChI=1S/C9H11Cl3NO3PS/c1-3-14-17(18,15-4-2)16-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss		Male/Female	Not reported	18.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	no data	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	no data	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	no data	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	no data	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	no data	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Chlorpyrifos	220-864-4	2921-88-2	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	no data	Negative			RMS: Spain	Chlorpyrifos	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance chlorpyrifos	31Jan2011	2011	doi:10.2903/j.efsa.2011.1961
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA1978			Not reported			yes	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM571			Not reported			yes	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM611			Not reported			yes	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP67			Not reported			yes	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Inconclusive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	GY5027			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	GY4015			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	GY5027			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	GY4015			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	5-hydroxy-benzimidazol-2-yl		22769-68-2	methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate	Not in list	C9H9N3O3	COC(=O)NC1=NC2=C(N1)C=C(C=C2)O	InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	5-hydroxy-benzimidazol-2-yl		22769-68-2	methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate	Not in list	C9H9N3O3	COC(=O)NC1=NC2=C(N1)C=C(C=C2)O	InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	5-hydroxy-benzimidazol-2-yl		22769-68-2	methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate	Not in list	C9H9N3O3	COC(=O)NC1=NC2=C(N1)C=C(C=C2)O	InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	5-hydroxy-benzimidazol-2-yl		22769-68-2	methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate	Not in list	C9H9N3O3	COC(=O)NC1=NC2=C(N1)C=C(C=C2)O	InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	5-hydroxy-benzimidazol-2-yl		22769-68-2	methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate	Not in list	C9H9N3O3	COC(=O)NC1=NC2=C(N1)C=C(C=C2)O	InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	5-hydroxy-benzimidazol-2-yl		22769-68-2	methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate	Not in list	C9H9N3O3	COC(=O)NC1=NC2=C(N1)C=C(C=C2)O	InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	5-hydroxy-benzimidazol-2-yl		22769-68-2	methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate	Not in list	C9H9N3O3	COC(=O)NC1=NC2=C(N1)C=C(C=C2)O	InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	5-hydroxy-benzimidazol-2-yl		22769-68-2	methyl N-(6-hydroxy-1H-benzimidazol-2-yl)carbamate	Not in list	C9H9N3O3	COC(=O)NC1=NC2=C(N1)C=C(C=C2)O	InChI=1S/C9H9N3O3/c1-15-9(14)12-8-10-6-3-2-5(13)4-7(6)11-8/h2-4,13H,1H3,(H2,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Inconclusive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male/Female	oral: feed			no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Oregon-R		Male	Not reported			no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mouse spot test	in vivo	Equivalent or similar to	OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test)	No data	Acceptable	House mouse (as animal)	Not reported		Female	Not reported			yes	not applicable	Inconclusive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	8	Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	8	Male/Female	oral: unspecified	6.0000000000	h	no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	8	Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	4	No data	oral: unspecified	6.0000000000	h	no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	4	No data	oral: unspecified	30.0000000000	h	no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	BDF1 mouse	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Positive		direct evidence-cytotoxicity	RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI		Male/Female	Not reported			no data	not applicable	Positive		no evidence	RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI		Male/Female	Not reported			no data	not applicable	Positive		no evidence	RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	ICR		No data	oral: unspecified			no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	ICR		No data	Not reported			no data	not applicable	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	ICR	6	Male	oral: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar		No data	oral: gavage	6.0000000000	h	yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar		No data	oral: unspecified	6.0000000000	h	yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar		No data	oral: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar		No data	oral: gavage			yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar		No data	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar		No data	oral: unspecified	72.0000000000	h	yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar		No data	oral: gavage	4.0000000000	h	yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	20	Male	intraperitoneal			yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	20	Male	intraperitoneal			yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	22	Male	oral: gavage			yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	embryo cells			Not reported			no data	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	oral: feed			no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is part of a group but not included in the group assessment	Thiophanate-methyl	245-740-7	23564-05-8	methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate	Thiophanate-methyl	C12H14N4O4S2	COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC	InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	BDF1 mouse	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is part of a group but not included in the group assessment	Thiophanate-methyl	245-740-7	23564-05-8	methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate	Thiophanate-methyl	C12H14N4O4S2	COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC	InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	BDF1 mouse	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported	5	Male	oral: gavage	22.0000000000	D	yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Inconclusive			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR		Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley		Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley		Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	3	Male	oral: gavage	25.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	no data	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	no data	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	no data	Negative			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	2-(4-tert-butylphenyl)ethanol		34386-42-0	1-(4-tert-butylphenyl)ethanol	Not in list	C12H18O	CC(C1=CC=C(C=C1)C(C)(C)C)O	InChI=1S/C12H18O/c1-9(13)10-5-7-11(8-6-10)12(2,3)4/h5-9,13H,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	no data	Positive			RMS: Greece	Fenazaquin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	quinazolin-4-ol	207-735-8	491-36-1	1H-quinazolin-4-one	Not in list	C8H6N2O	C1=CC=C2C(=C1)C(=O)N=CN2	InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin (Addendum to DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	quinazolin-4-ol	207-735-8	491-36-1	1H-quinazolin-4-one	Not in list	C8H6N2O	C1=CC=C2C(=C1)C(=O)N=CN2	InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin (Addendum to DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	quinazolin-4-ol	207-735-8	491-36-1	1H-quinazolin-4-one	Not in list	C8H6N2O	C1=CC=C2C(=C1)C(=O)N=CN2	InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin (Addendum to DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	quinazolin-4-ol	207-735-8	491-36-1	1H-quinazolin-4-one	Not in list	C8H6N2O	C1=CC=C2C(=C1)C(=O)N=CN2	InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin (Addendum to DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	quinazolin-4-ol	207-735-8	491-36-1	1H-quinazolin-4-one	Not in list	C8H6N2O	C1=CC=C2C(=C1)C(=O)N=CN2	InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin (Addendum to DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	quinazolin-4-ol	207-735-8	491-36-1	1H-quinazolin-4-one	Not in list	C8H6N2O	C1=CC=C2C(=C1)C(=O)N=CN2	InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin (Addendum to DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	quinazolin-4-ol	207-735-8	491-36-1	1H-quinazolin-4-one	Not in list	C8H6N2O	C1=CC=C2C(=C1)C(=O)N=CN2	InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin (Addendum to DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	quinazolin-4-ol	207-735-8	491-36-1	1H-quinazolin-4-one	Not in list	C8H6N2O	C1=CC=C2C(=C1)C(=O)N=CN2	InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin (Addendum to DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	quinazolin-4-ol	207-735-8	491-36-1	1H-quinazolin-4-one	Not in list	C8H6N2O	C1=CC=C2C(=C1)C(=O)N=CN2	InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fenazaquin (Addendum to DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is a metabolite of the substance	quinazolin-4-ol	207-735-8	491-36-1	1H-quinazolin-4-one	Not in list	C8H6N2O	C1=CC=C2C(=C1)C(=O)N=CN2	InChI=1S/C8H6N2O/c11-8-6-3-1-2-4-7(6)9-5-10-8/h1-5H,(H,9,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fenazaquin (Addendum to DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Fenazaquin		120928-09-8	single chemical entity	Component is identical to the substance	Fenazaquin		120928-09-8	4-[2-(4-tert-butylphenyl)ethoxy]quinazoline	Fenazaquin	C20H22N2O	CC(C)(C)C3=CC=C(C=C3)CCOC1=NC=NC2=C1C=CC=C2	InChI=1S/C20H22N2O/c1-20(2,3)16-10-8-15(9-11-16)12-13-23-19-17-6-4-5-7-18(17)21-14-22-19/h4-11,14H,12-13H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	6	Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Greece	Fenazaquin (Additional report to volume 3)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenazaquin	04Apr2013	2013	doi:10.2903/j.efsa.2013.3166
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is part of a group assessment	Geranyl acetate	203-341-5	105-87-3	[(2E)-3,7-dimethylocta-2,6-dienyl] acetate	Not in list	C12H20O2	CC(=CCCC(=CCOC(=O)C)C)C	InChI=1S/C12H20O2/c1-10(2)6-5-7-11(3)8-9-14-12(4)13/h6,8H,5,7,9H2,1-4H3/b11-8+	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Geraniol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Ambiguous			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Carbaryl	200-555-0	63-25-2	single chemical entity	Component is identical to the substance	Carbaryl	200-555-0	63-25-2	1-naphthyl methylcarbamate	Carbaryl	C12H11NO2	CNC(=O)Oc1cccc2ccccc12	InChI=1/C12H11NO2/c1-13-12(14)15-11-8-4-6-9-5-2-3-7-10(9)11/h2-8H,1H3,(H,13,14)	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: gavage			yes	not applicable	Negative			RMS: Spain	Carbaryl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance carbaryl	13Jun2006	2006	doi:10.2903/j.efsa.2006.80r
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Fenpyroximate		134098-61-6	single chemical entity	Component is identical to the substance	Fenpyroximate		134098-61-6	Tert-butyl 4-[[(E)-(1,3-dimethyl-5-phenoxypyrazol-4-yl)methylideneamino]oxymethyl]benzoate	Fenpyroximate	C24H27N3O4	CC1=NN(C(=C1/C=N/OCC2=CC=C(C=C2)C(=O)OC(C)(C)C)OC3=CC=CC=C3)C	InChI=1S/C24H27N3O4/c1-17-21(22(27(5)26-17)30-20-9-7-6-8-10-20)15-25-29-16-18-11-13-19(14-12-18)23(28)31-24(2,3)4/h6-15H,16H2,1-5H3/b25-15+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Fenpyroximate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyroximate	13Dec2013	2013	doi:10.2903/j.efsa.2013.3493
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Ambiguous			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Ambiguous	no information		RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	no information		RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Inconclusive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Inconclusive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	8	No data	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	8	No data	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	8	No data	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	3	Male	oral: unspecified	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	8	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Positive		direct evidence-cytotoxicity	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	No data	Acceptable	House mouse (as animal)	CD-1	4	Male	intraperitoneal	4.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	No data	Acceptable	House mouse (as animal)	CD-1	4	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	6	Female	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	6	Female	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	8	Male	intraperitoneal	6.0000000000	h	yes	not applicable	Positive		direct evidence-cytotoxicity	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	No data	Acceptable	House mouse (as animal)	CD-1	4	Male	intraperitoneal	4.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	No data	Acceptable	House mouse (as animal)	CD-1	4	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	6	Female	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male	oral: gavage	42.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male	oral: gavage	66.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male	oral: gavage	18.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Not reported	200	Male	oral: feed			yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss		No data	Not reported			no data	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			no data	without	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss		No data	Not reported			no data	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	Hep G2 human cell line			Not reported			no data	without	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			no data	without	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss		No data	Not reported			no data	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss		No data	Not reported			no data	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss		No data	Not reported			no data	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No data	Acceptable	Human (as organism)	Hep G2 human cell line			Not reported			no data	no data	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed			no data	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Positive	small colonies		RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	inhalation: unspecified			no data	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		No data	inhalation: unspecified			no data	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		No data	inhalation: unspecified			no data	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	inhalation: unspecified			no data	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		No data	inhalation: unspecified			no data	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	other			no data	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	inhalation: unspecified			no data	not applicable	Positive			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	4	Male/Female	intraperitoneal	6.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	4	Male/Female	intraperitoneal	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	4	Male/Female	intraperitoneal	6.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	4	Male/Female	intraperitoneal	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	Rat (as animal)	Wistar	24	Male	inhalation: unspecified			no data	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	CD-1		Male	inhalation: unspecified			yes	not applicable	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 pKM 101 E. coli			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 pKM 101 E. coli			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is identical to the substance	Fluazifop-P-butyl		79241-46-6	Butyl (2R)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Fluazifop-P-butyl	C19H20F3NO4	CCCCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC=C(C=C2)C(F)(F)F	InChI=1S/C19H20F3NO4/c1-3-4-11-25-18(24)13(2)26-15-6-8-16(9-7-15)27-17-10-5-14(12-23-17)19(20,21)22/h5-10,12-13H,3-4,11H2,1-2H3/t13-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Positive			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Positive			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		direct evidence-cytotoxicity	RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar		Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar		Male	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Fluazifop-P	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fluazifop-P (Addendum to the Additional Report of Volume 3 B6 – B7)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Fluazifop-P-butyl		79241-46-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fluazifop-P (Addendum to the Additional Report of Volume 3 B6 – B7)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluazifop-P (evaluated variant fluazifop-P-butyl)	08Nov2012	2012	doi:10.2903/j.efsa.2012.2945
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	LT2 S. typhimurium			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Aspergillus nidulans (as organism)	Not reported			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA92			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA92			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Ambiguous			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Ambiguous			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Ambiguous			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Ambiguous			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 472 (Genetic Toxicology: Escherichia coli, Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	XV 185-14C S. cerevisiae			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	XV 185-14C S. cerevisiae			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CHY832 E. coli			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CHY832 E. coli			Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	embryo cells			Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	NMRI		No data	Not reported			no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal			no data	not applicable	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Aspergillus nidulans (as organism)	Strain P Aspergillus nidulans			Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Aspergillus nidulans (as organism)	Strain P Aspergillus nidulans			Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Aspergillus nidulans (as organism)	Not reported			Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	with	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	with	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-proficient			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM871			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM871			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP67			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP67			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	Strain T2 S. cerevisiae			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	Strain T1 S. cerevisiae			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	Strain T1 S. cerevisiae			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	Strain T2 S. cerevisiae			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)				Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)				Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			no data	with	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	58-161 E.coli			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	GY4015			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	GY5027			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	Strain T2 S. cerevisiae			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	Strain T1 S. cerevisiae			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	Strain T2 S. cerevisiae			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	Strain T1 S. cerevisiae			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	Strain JD1 S. cerevisiae			Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	Strain JD1 S. cerevisiae			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	3T3			Not reported			no data	without	Ambiguous			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	kidney cells			Not reported			no data	with	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	kidney cells			Not reported			no data	with	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	kidney cells			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	kidney cells			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			no data	with	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	embryo cells			Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	embryo cells			Not reported			no data	without	Positive			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	embryo cells			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Drosophila melanogaster (as animal)	Not reported		Female	oral: feed			no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed			no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed			no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	NMRI		Male	Not reported			no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	ICR		Male	oral: feed	49.0000000000	D	no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1		Male/Female	Not reported			no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	NMRI		Male/Female	Not reported			no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		Male	intraperitoneal			no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP100			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP100			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	NMRI		Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	NMRI		Male/Female	oral: unspecified	72.0000000000	h	no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	NMRI		Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Hungary	Amitrole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Hungary	Amitrole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Hungary	Amitrole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Hungary	Amitrole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Hungary	Amitrole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Hungary	Amitrole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Hungary	Amitrole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Hungary	Amitrole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Hungary	Amitrole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Hungary	Amitrole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Amitrole	200-521-5	61-82-5	single chemical entity	Component is identical to the substance	Amitrole	200-521-5	61-82-5	1-H-1,2,4-triazol-3-amine	Amitrole	C2H4N4	C1=NNC(=N1)N	InChI=1S/C2H4N4/c3-2-4-1-5-6-2/h1H,(H3,3,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: France	Amitrole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance amitrole	01Jul2014	2014	doi:10.2903/j.efsa.2014.3742
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Tif:RAIf(SPF) Rat	4	Male	oral: gavage	3.0000000000	D	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Tif:RAIf(SPF) Rat	5	Male	oral: gavage	3.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: gavage	30.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Tif:RAIf(SPF) Rat	4	Male	oral: gavage	4.0000000000	h	yes	not applicable	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Tif:RAIf(SPF) Rat	4	Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is identical to the substance	Fludioxonil		131341-86-1	4-(2,2-difluoro-1,3-benzodioxol-4-yl)-1H-pyrrole-3-carbonitrile	Fludioxonil	C12H6F2N2O2	FC3(F)OC(C(O3)=CC=C2)=C2C1=CNC=C1C#N	InChI=1S/C12H6F2N2O2/c13-12(14)17-10-3-1-2-8(11(10)18-12)9-6-16-5-7(9)4-15/h1-3,5-6,16H	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	30	Male	oral: gavage			yes	not applicable	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	(2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid			2,2-difluoro-1,3-benzodioxole-4-carboxylic acid	Not in list	C8H4F2O4	O=C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	(2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid			2,2-difluoro-1,3-benzodioxole-4-carboxylic acid	Not in list	C8H4F2O4	O=C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	(2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid			2,2-difluoro-1,3-benzodioxole-4-carboxylic acid	Not in list	C8H4F2O4	O=C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	(2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid			2,2-difluoro-1,3-benzodioxole-4-carboxylic acid	Not in list	C8H4F2O4	O=C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	(2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid			2,2-difluoro-1,3-benzodioxole-4-carboxylic acid	Not in list	C8H4F2O4	O=C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	(2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid			2,2-difluoro-1,3-benzodioxole-4-carboxylic acid	Not in list	C8H4F2O4	O=C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	(2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid			2,2-difluoro-1,3-benzodioxole-4-carboxylic acid	Not in list	C8H4F2O4	O=C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	(2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid			2,2-difluoro-1,3-benzodioxole-4-carboxylic acid	Not in list	C8H4F2O4	O=C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	(2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid			2,2-difluoro-1,3-benzodioxole-4-carboxylic acid	Not in list	C8H4F2O4	O=C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	(2,2-difluoro-benzo[1,3]dioxol-4-carbocyclic acid			2,2-difluoro-1,3-benzodioxole-4-carboxylic acid	Not in list	C8H4F2O4	O=C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C8H4F2O4/c9-8(10)13-5-3-1-2-4(7(11)12)6(5)14-8/h1-3H,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile	Not in list	C12H4F2N2O4	N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12	InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile	Not in list	C12H4F2N2O4	N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12	InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile	Not in list	C12H4F2N2O4	N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12	InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile	Not in list	C12H4F2N2O4	N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12	InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile	Not in list	C12H4F2N2O4	N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12	InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile	Not in list	C12H4F2N2O4	N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12	InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile	Not in list	C12H4F2N2O4	N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12	InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile	Not in list	C12H4F2N2O4	N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12	InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile	Not in list	C12H4F2N2O4	N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12	InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrole-3-carbonitrile	Not in list	C12H4F2N2O4	N#CC=3C(=O)NC(=O)C=3c1cccc2OC(F)(F)Oc12	InChI=1/C12H4F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide			2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide	Not in list	C9H7F2NO4	NC(=O)C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide			2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide	Not in list	C9H7F2NO4	NC(=O)C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide			2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide	Not in list	C9H7F2NO4	NC(=O)C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide			2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide	Not in list	C9H7F2NO4	NC(=O)C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide			2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide	Not in list	C9H7F2NO4	NC(=O)C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide			2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide	Not in list	C9H7F2NO4	NC(=O)C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide			2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide	Not in list	C9H7F2NO4	NC(=O)C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide			2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide	Not in list	C9H7F2NO4	NC(=O)C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide			2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide	Not in list	C9H7F2NO4	NC(=O)C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	2-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2-hydroxy-acetamide			2-(2,2-difluoro-1,3-benzodioxol-4-yl)-2-hydroxyacetamide	Not in list	C9H7F2NO4	NC(=O)C(O)c1cccc2OC(F)(F)Oc12	InChI=1/C9H7F2NO4/c10-9(11)15-5-3-1-2-4(7(5)16-9)6(13)8(12)14/h1-3,6,13H,(H2,12,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile	Not in list	C12H6F2N2O4	O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12	InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile	Not in list	C12H6F2N2O4	O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12	InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile	Not in list	C12H6F2N2O4	O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12	InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile	Not in list	C12H6F2N2O4	O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12	InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile	Not in list	C12H6F2N2O4	O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12	InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile	Not in list	C12H6F2N2O4	O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12	InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile	Not in list	C12H6F2N2O4	O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12	InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile	Not in list	C12H6F2N2O4	O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12	InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile	Not in list	C12H6F2N2O4	O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12	InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	4-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-2,5-dioxo-pyrrolidine-3-carbonitrile			4-(2,2-difluoro-1,3-benzodioxol-4-yl)-2,5-dioxopyrrolidine-3-carbonitrile	Not in list	C12H6F2N2O4	O=C3NC(=O)C(C#N)C3c1cccc2OC(F)(F)Oc12	InChI=1/C12H6F2N2O4/c13-12(14)19-7-3-1-2-5(9(7)20-12)8-6(4-15)10(17)16-11(8)18/h1-3,6,8H,(H,16,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Ambiguous	no information		RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Alpk:APf SD Rat	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
Fludioxonil		131341-86-1	single chemical entity	Component is a metabolite of the substance	3-carbamoyl-2-cyano-3-(2,2-difluoro-benzo[1,3]dioxol-4-yl)-oxirane-2-carbocyclic acid			3-carbamoyl-2-cyano-3-(2,2-difluoro-1,3-benzodioxol-4-yl)oxirane-2-carboxylic acid	Not in list	C12H6F2N2O6	O=C(O)C3(C#N)OC3(c1cccc2OC(F)(F)Oc12)C(N)=O	InChI=1/C12H6F2N2O6/c13-12(14)20-6-3-1-2-5(7(6)21-12)11(8(16)17)10(4-15,22-11)9(18)19/h1-3H,(H2,16,17)(H,18,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Wistar	5	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Fludioxonil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fludioxonil	17Aug2007	2007	doi:10.2903/j.efsa.2007.110r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	Not reported		Male	oral: gavage			yes	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3076			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3052			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3052			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3076			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3052			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3076			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3076			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3052			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3076			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3052			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3076			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	C3052			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Human (as organism)	Not reported			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Human (as organism)	Not reported			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	no information		RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	other			no data	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed			no data	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	no data	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	no data	Positive	no information		RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is part of a group assessment	2-Phenylphenol sodium salt	205-055-6	132-27-4	2-Phenylphenol sodium salt	Not in list	C12H9NaO	C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+]	InChI=1S/C12H10O.Na/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9,13H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	no data	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	no data	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM571			Not reported			no data	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP100			Not reported			no data	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Not reported			Not reported			no data	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Not reported			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Not reported			Not reported			no data	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Not reported			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Not reported			Not reported			no data	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Not reported			Not reported			no data	with	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Not reported			Not reported			no data	with	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Not reported			Not reported			no data	with	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Not reported			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	Thymus cell			Not reported			no data	no data	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	Thymus cell			Not reported			no data	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	Thymus cell			Not reported			no data	no data	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	leukemia cells (HL-60)			Not reported			yes, concurrent vehicle	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	leukemia cells (HL-60)			Not reported			yes, concurrent vehicle	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	leukemia cells (HL-60)			Not reported			yes, concurrent vehicle	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Human (as organism)	leukemia cells (HL-60)			Not reported			yes, concurrent vehicle	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	leukemia cells (HL-60)			Not reported			yes, concurrent vehicle	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	leukemia cells (HL-60)			Not reported			yes, concurrent vehicle	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	leukemia cells (HL-60)			Not reported			yes, concurrent vehicle	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	leukemia cells (HL-60)			Not reported			yes, concurrent vehicle	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is part of a group assessment	2-Phenylphenol sodium salt	205-055-6	132-27-4	2-Phenylphenol sodium salt	Not in list	C12H9NaO	C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+]	InChI=1S/C12H10O.Na/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9,13H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	6	No data	oral: feed	13.0000000000	week	no data	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	Thymus cell			Not reported			no data	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	Thymus cell			Not reported			no data	without	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	Thymus cell			Not reported			no data	with	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	Thymus cell			Not reported			no data	without	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	Hep G2 human cell line			Not reported			no data	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar		Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	4	No data	oral: feed	24.0000000000	h	yes	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: gavage	8.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: gavage	8.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: unspecified			yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: unspecified			yes, concurrent vehicle	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: unspecified			yes, concurrent vehicle	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: unspecified			yes, concurrent vehicle	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: unspecified			yes, concurrent vehicle	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: unspecified			yes, concurrent vehicle	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	CD-1	4	No data	oral: unspecified			yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Fischer344	2	Male	other	10.0000000000	min	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Fischer344	2	Male	other	10.0000000000	min	yes, concurrent vehicle	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Fischer344	2	Male	other	10.0000000000	min	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Fischer344	2	Male/Female	other	10.0000000000	min	yes, concurrent vehicle	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Fischer344	2	Male/Female	other	10.0000000000	min	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Fischer344	2	Male/Female	other	10.0000000000	min	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	4	Male	oral: gavage	16.0000000000	h	no data	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is part of a group assessment	2-Phenylphenol sodium salt	205-055-6	132-27-4	2-Phenylphenol sodium salt	Not in list	C12H9NaO	C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+]	InChI=1S/C12H10O.Na/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9,13H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	4	Male	oral: gavage	16.0000000000	h	no data	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is part of a group assessment	2-Phenylphenol sodium salt	205-055-6	132-27-4	2-Phenylphenol sodium salt	Not in list	C12H9NaO	C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+]	InChI=1S/C12H10O.Na/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9,13H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	4	Male	oral: gavage	16.0000000000	h	no data	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is part of a group assessment	2-Phenylphenol sodium salt	205-055-6	132-27-4	2-Phenylphenol sodium salt	Not in list	C12H9NaO	C1=CC=C(C=C1)C2=CC=CC=C2[O-].[Na+]	InChI=1S/C12H10O.Na/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;/h1-9,13H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	4	Male	oral: gavage	16.0000000000	h	no data	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	4	Male	oral: gavage	16.0000000000	h	no data	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344	4	Male	oral: gavage	16.0000000000	h	no data	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344		Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344		Male	oral: gavage	24.0000000000	h	yes	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344		Male	oral: gavage	24.0000000000	h	yes	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Fischer344		Male	oral: gavage	24.0000000000	h	yes	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	C3H	15	Male	oral: gavage			yes	not applicable	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	no data	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	no data	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is identical to the substance	2-Phenylphenol	201-993-5	90-43-7	2-Phenylphenol	2-phenylphenol	C12H10O	C1=CC=C(C=C1)C2=CC=CC=C2O	InChI=1S/C12H10O/c13-12-9-5-4-8-11(12)10-6-2-1-3-7-10/h1-9,13H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	no data	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is part of a group but not included in the group assessment	Sodium aluminium sulphate	233-277-3	10102-71-3	aluminum;sodium;disulfate	Aluminium ammonium sulphate	AlNaO8S2	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Na+].[Al+3]	InChI=1S/Al.Na.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is part of a group but not included in the group assessment	Sodium aluminium sulphate	233-277-3	10102-71-3	aluminum;sodium;disulfate	Aluminium ammonium sulphate	AlNaO8S2	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Na+].[Al+3]	InChI=1S/Al.Na.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	no data	Negative			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is part of a group but not included in the group assessment	Sodium aluminium sulphate	233-277-3	10102-71-3	aluminum;sodium;disulfate	Aluminium ammonium sulphate	AlNaO8S2	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Na+].[Al+3]	InChI=1S/Al.Na.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	no data	Negative			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is part of a group but not included in the group assessment	Sodium aluminium sulphate	233-277-3	10102-71-3	aluminum;sodium;disulfate	Aluminium ammonium sulphate	AlNaO8S2	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Na+].[Al+3]	InChI=1S/Al.Na.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	no data	Negative			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium chloride	231-208-1	7446-70-0	trichloroalumane	Not in list	AlCl3	[Al](Cl)(Cl)Cl	InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium oxide	618-619-5	1344-28-1	dialuminum;oxygen(2-)	Not in list	Al2O3	[O-2].[O-2].[O-2].[Al+3].[Al+3]	InChI=1S/2Al.3O/q2*+3;3*-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium oxide	618-619-5	1344-28-1	dialuminum;oxygen(2-)	Not in list	Al2O3	[O-2].[O-2].[O-2].[Al+3].[Al+3]	InChI=1S/2Al.3O/q2*+3;3*-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium chloride	231-208-1	7446-70-0	trichloroalumane	Not in list	AlCl3	[Al](Cl)(Cl)Cl	InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium chloride	231-208-1	7446-70-0	trichloroalumane	Not in list	AlCl3	[Al](Cl)(Cl)Cl	InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium chloride	231-208-1	7446-70-0	trichloroalumane	Not in list	AlCl3	[Al](Cl)(Cl)Cl	InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium oxide	618-619-5	1344-28-1	dialuminum;oxygen(2-)	Not in list	Al2O3	[O-2].[O-2].[O-2].[Al+3].[Al+3]	InChI=1S/2Al.3O/q2*+3;3*-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium oxide	618-619-5	1344-28-1	dialuminum;oxygen(2-)	Not in list	Al2O3	[O-2].[O-2].[O-2].[Al+3].[Al+3]	InChI=1S/2Al.3O/q2*+3;3*-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			no data	no data	Negative			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Human (as organism)		10	Male/Female	Not reported			yes	not applicable	Positive			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	lymphocytes	10	Male/Female	Not reported			yes	no data	Positive			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes	10	Male/Female	Not reported			yes	no data	Positive			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)				Not reported			no data	no data	Positive			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	2	No data	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	6	No data	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss	5	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium potassium sulphate	233-141-3	10043-67-1	aluminum;potassium;disulfate	Aluminium potassium sulphate	AlKO8S2	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[K+]	InChI=1S/Al.K.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Not reported		Male	oral: unspecified	24.0000000000	h	yes	not applicable	Positive			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is identical to the substance	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Not reported		Male	oral: unspecified	24.0000000000	h	yes	not applicable	Positive			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium potassium sulphate	233-141-3	10043-67-1	aluminum;potassium;disulfate	Aluminium potassium sulphate	AlKO8S2	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[K+]	InChI=1S/Al.K.2H2O4S/c;;2*1-5(2,3)4/h;;2*(H2,1,2,3,4)/q+3;+1;;/p-4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Not reported		Male	oral: unspecified	24.0000000000	h	yes	not applicable	Positive			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Not reported		Male	oral: unspecified	24.0000000000	h	yes	not applicable	Positive			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminum	231-072-3	7429-90-5	Aluminum	Aluminum (Al)	Al	[Al]	InChI=1S/Al	metal	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Human (as organism)	astrocytes cell			Not reported			no data	no data	Positive			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminum	231-072-3	7429-90-5	Aluminum	Aluminum (Al)	Al	[Al]	InChI=1S/Al	metal	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium sulphate	233-135-0	10043-01-3	single chemical entity	Component is part of a group but not included in the group assessment	Aluminum	231-072-3	7429-90-5	Aluminum	Aluminum (Al)	Al	[Al]	InChI=1S/Al	metal	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	astrocytes cell			Not reported			no data	no data	Positive			RMS: Spain	Aluminium sulphate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium sulfate	05Nov2010	2010	doi:10.2903/j.efsa.2010.1889
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Gibberellins	201-001-0	77-06-5	complex product: derived from botanical sources	Component is identical to the substance	Gibberellins	201-001-0	77-06-5	2,7-dihydroxy-1-methyl-8-methylidene-13-oxo-1,2,4b,5,6,7,8,9,10,10a-decahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid	Not in list	C19H22O6	CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O	InChI=1S/C19H22O6/c1-9-7-17-8-18(9,24)5-3-10(17)19-6-4-11(20)16(2,15(23)25-19)13(19)12(17)14(21)22/h4,6,10-13,20,24H,1,3,5,7-8H2,2H3,(H,21,22)/t10?,11-,12+,13+,16?,17-,18-,19+/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Hungary	Gibberellins - GA4/GA7	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance gibberellins (GA4, GA7)1 (approved as giberelline)	10Jan2012	2012	doi:10.2903/j.efsa.2012.2502
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper oxychloride			copper;chloro hypochlorite	Not in list	Cl2CuO+2	O(Cl)Cl.[Cu+2]	InChI=1S/Cl2O.Cu/c1-3-2;/q;+2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper oxychloride			copper;chloro hypochlorite	Not in list	Cl2CuO+2	O(Cl)Cl.[Cu+2]	InChI=1S/Cl2O.Cu/c1-3-2;/q;+2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper oxychloride			copper;chloro hypochlorite	Not in list	Cl2CuO+2	O(Cl)Cl.[Cu+2]	InChI=1S/Cl2O.Cu/c1-3-2;/q;+2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper oxychloride			copper;chloro hypochlorite	Not in list	Cl2CuO+2	O(Cl)Cl.[Cu+2]	InChI=1S/Cl2O.Cu/c1-3-2;/q;+2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper oxychloride			copper;chloro hypochlorite	Not in list	Cl2CuO+2	O(Cl)Cl.[Cu+2]	InChI=1S/Cl2O.Cu/c1-3-2;/q;+2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper oxychloride			copper;chloro hypochlorite	Not in list	Cl2CuO+2	O(Cl)Cl.[Cu+2]	InChI=1S/Cl2O.Cu/c1-3-2;/q;+2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper oxychloride			copper;chloro hypochlorite	Not in list	Cl2CuO+2	O(Cl)Cl.[Cu+2]	InChI=1S/Cl2O.Cu/c1-3-2;/q;+2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper oxychloride			copper;chloro hypochlorite	Not in list	Cl2CuO+2	O(Cl)Cl.[Cu+2]	InChI=1S/Cl2O.Cu/c1-3-2;/q;+2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper oxychloride			copper;chloro hypochlorite	Not in list	Cl2CuO+2	O(Cl)Cl.[Cu+2]	InChI=1S/Cl2O.Cu/c1-3-2;/q;+2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper oxychloride			copper;chloro hypochlorite	Not in list	Cl2CuO+2	O(Cl)Cl.[Cu+2]	InChI=1S/Cl2O.Cu/c1-3-2;/q;+2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Bordeaux mixture		1333-22-8	tetracopper;hexahydroxide;sulfate	Not in list	Cu4H6O10S	[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Bordeaux mixture		1333-22-8	tetracopper;hexahydroxide;sulfate	Not in list	Cu4H6O10S	[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Bordeaux mixture		1333-22-8	tetracopper;hexahydroxide;sulfate	Not in list	Cu4H6O10S	[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Bordeaux mixture		1333-22-8	tetracopper;hexahydroxide;sulfate	Not in list	Cu4H6O10S	[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Bordeaux mixture		1333-22-8	tetracopper;hexahydroxide;sulfate	Not in list	Cu4H6O10S	[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Bordeaux mixture		1333-22-8	tetracopper;hexahydroxide;sulfate	Not in list	Cu4H6O10S	[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Bordeaux mixture		1333-22-8	tetracopper;hexahydroxide;sulfate	Not in list	Cu4H6O10S	[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Bordeaux mixture		1333-22-8	tetracopper;hexahydroxide;sulfate	Not in list	Cu4H6O10S	[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Bordeaux mixture		1333-22-8	tetracopper;hexahydroxide;sulfate	Not in list	Cu4H6O10S	[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Bordeaux mixture		1333-22-8	tetracopper;hexahydroxide;sulfate	Not in list	Cu4H6O10S	[OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/4Cu.H2O4S.6H2O/c;;;;1-5(2,3)4;;;;;;/h;;;;(H2,1,2,3,4);6*1H2/q4*+2;;;;;;;/p-8	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper (I) oxide	215-270-7	1317-39-1	Copper;hydrate	Not in list	Cu2H2O	O.[Cu].[Cu]	InChI=1S/2Cu.H2O/h;;1H2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper (I) oxide	215-270-7	1317-39-1	Copper;hydrate	Not in list	Cu2H2O	O.[Cu].[Cu]	InChI=1S/2Cu.H2O/h;;1H2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper (I) oxide	215-270-7	1317-39-1	Copper;hydrate	Not in list	Cu2H2O	O.[Cu].[Cu]	InChI=1S/2Cu.H2O/h;;1H2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper (I) oxide	215-270-7	1317-39-1	Copper;hydrate	Not in list	Cu2H2O	O.[Cu].[Cu]	InChI=1S/2Cu.H2O/h;;1H2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Oxine copper	233-841-9	10380-28-6	copper;quinolin-8-olate	Not in list	C18H12CuN2O2	C1=CC2=C(C(=C1)[O-])N=CC=C2.C1=CC2=C(C(=C1)[O-])N=CC=C2.[Cu+2]	InChI=1S/2C9H7NO.Cu/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper chloride	231-210-2	7447-39-4	dichlorocopper	Not in list	Cl2Cu	Cl[Cu]Cl	InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper chloride	231-210-2	7447-39-4	dichlorocopper	Not in list	Cl2Cu	Cl[Cu]Cl	InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper chloride	231-210-2	7447-39-4	dichlorocopper	Not in list	Cl2Cu	Cl[Cu]Cl	InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper chloride	231-210-2	7447-39-4	dichlorocopper	Not in list	Cl2Cu	Cl[Cu]Cl	InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper chloride	231-210-2	7447-39-4	dichlorocopper	Not in list	Cl2Cu	Cl[Cu]Cl	InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper chloride	231-210-2	7447-39-4	dichlorocopper	Not in list	Cl2Cu	Cl[Cu]Cl	InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper chloride	231-210-2	7447-39-4	dichlorocopper	Not in list	Cl2Cu	Cl[Cu]Cl	InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper chloride	231-210-2	7447-39-4	dichlorocopper	Not in list	Cl2Cu	Cl[Cu]Cl	InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper chloride	231-210-2	7447-39-4	dichlorocopper	Not in list	Cl2Cu	Cl[Cu]Cl	InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper chloride	231-210-2	7447-39-4	dichlorocopper	Not in list	Cl2Cu	Cl[Cu]Cl	InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper nitrate	221-838-5	3251-23-8	copper;dinitrate	Not in list	CuN2O6	[N+](=O)([O-])[O-].[N+](=O)([O-])[O-].[Cu+2]	InChI=1S/Cu.2NO3/c;2*2-1(3)4/q+2;2*-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	no data	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper nitrate	221-838-5	3251-23-8	copper;dinitrate	Not in list	CuN2O6	[N+](=O)([O-])[O-].[N+](=O)([O-])[O-].[Cu+2]	InChI=1S/Cu.2NO3/c;2*2-1(3)4/q+2;2*-1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	no data	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	5	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	5	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	intraperitoneal	6.0000000000	h	no data	not applicable	Positive		no evidence	RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	subcutaneous	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	6	Male	intraperitoneal	6.0000000000	h	yes	not applicable	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	6	Male	intraperitoneal	12.0000000000	h	yes	not applicable	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Copper II sulphate pentahydrate	616-477-9	7758-99-8	copper;sulfate;pentahydrate	Not in list	CuSO4.5H2O	O.O.O.O.O.[O-]S(=O)(=O)[O-].[Cu+2]	InChI=1S/Cu.H2O4S.5H2O/c;1-5(2,3)4;;;;;/h;(H2,1,2,3,4);5*1H2/q+2;;;;;;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	6	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CBA	6	Male	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Copper	231-159-6	7440-50-8	single chemical entity	Component is part of a group assessment	Tribasic copper sulfate	215-582-3	1333-22-8	Tricopper;dihydroxide;disulfate	Tribasic copper sulfate	Cu3H2O10S2	[OH-].[OH-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Cu+2].[Cu+2].[Cu+2]	InChI=1S/3Cu.2H2O4S.2H2O/c;;;2*1-5(2,3)4;;/h;;;2*(H2,1,2,3,4);2*1H2/q3*+2;;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CBA	6	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Copper	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture.	22Oct2008	2008	doi:10.2903/j.efsa.2008.187r
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Wistar	24	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Wistar	24	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is identical to the substance	Flufenoxuron	417-680-3	101463-69-8	N-({4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}carbamoyl)-2,6-difluorobenzamide	Flufenoxuron	C21H11ClF6N2O3	O=C(NC(NC2=C(F)C=C(OC3=C(Cl)C=C(C(F)(F)F)C=C3)C=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C21H11ClF6N2O3/c22-12-8-10(21(26,27)28)4-7-17(12)33-11-5-6-16(15(25)9-11)29-20(32)30-19(31)18-13(23)2-1-3-14(18)24/h1-9H,(H2,29,30,31,32)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344		Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	N-[4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl urea			1-{4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluorophenyl}urea	Not in list	C14H9ClF4N2O2	Clc2cc(ccc2Oc1ccc(NC(N)=O)c(F)c1)C(F)(F)F	InChI=1/C14H9ClF4N2O2/c15-9-5-7(14(17,18)19)1-4-12(9)23-8-2-3-11(10(16)6-8)21-13(20)22/h1-6H,(H3,20,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: unspecified	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Flufenoxuron	417-680-3	101463-69-8	single chemical entity	Component is a metabolite of the substance	4-[2-Chloro-4-(trifluoromethyl)phenoxy-2-fluorobenzenamine			4-[2-chloro-4-(trifluoromethyl)phenoxy]-2-fluoroaniline	Not in list	C13H8ClF4NO	Clc2cc(ccc2Oc1ccc(N)c(F)c1)C(F)(F)F	InChI=1/C13H8ClF4NO/c14-9-5-7(13(16,17)18)1-4-12(9)20-8-2-3-11(19)10(15)6-8/h1-6H,19H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: unspecified	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Flufenoxuron	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flufenoxuron	14Mar2011	2011	doi:10.2903/j.efsa.2011.2088
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is identical to the substance	Fluometuron	218-500-4	2164-17-2	1,1-dimethyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron	C10H11F3N2O	CN(C)C(=O)Nc1cccc(c1)C(F)(F)F	InChI=1/C10H11F3N2O/c1-15(2)9(16)14-8-5-3-4-7(6-8)10(11,12)13/h3-6H,1-2H3,(H,14,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent no treatment	without	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent no treatment	with	Positive			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Fluometuron	218-500-4	2164-17-2	single chemical entity	Component is a metabolite of the substance	Desmethyl-fluometuron		3032-40-4	1-methyl-3-[3-(trifluoromethyl)phenyl]urea	Fluometuron metabolite (CGA 41686)	C9H9F3N2O	CNC(=O)NC1=CC=CC(=C1)C(F)(F)F	InChI=1S/C9H9F3N2O/c1-13-8(15)14-7-4-2-3-6(5-7)9(10,11)12/h2-5H,1H3,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Fluometuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluometuron	13Jan2011	2011	doi:10.2903/j.efsa.2011.1958
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	Strain JD1 S. cerevisiae			Not reported			yes	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	kidney cells			Not reported			no data	no data	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	Strain JD1 S. cerevisiae			Not reported			yes	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	Strain JD1 S. cerevisiae			Not reported			yes	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	Strain JD1 S. cerevisiae			Not reported			yes	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Chinese	6	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is part of a group assessment	Alpha-Cypermethrin	614-054-3	67375-30-8	[(R)-cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Not reported	12	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	6	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	6	Male/Female	oral: unspecified	8.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	CD-1	12	Male	oral: unspecified			yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		No data	oral: unspecified			no data	not applicable	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Not reported		Male/Female	oral: gavage	16.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	no data	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	not applicable	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	5	No data	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss	6	No data	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	5	No data	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	dermal	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	dermal	14.0000000000	D	yes	not applicable	Negative		no evidence	RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Cypermethrin	257-842-9	52315-07-8	[cyano-(3-phenoxyphenyl)methyl] 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate	Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	According to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed			no data	not applicable	Positive			RMS: Belgium	Cypermethrin	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is part of a group assessment	Desmethyl dichlorvos			methyl hydrogen phosphate	Not in list	CH4O4P	[O-]P(=O)(O)OC	InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is part of a group assessment	Desmethyl dichlorvos			methyl hydrogen phosphate	Not in list	CH4O4P	[O-]P(=O)(O)OC	InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is part of a group assessment	Desmethyl dichlorvos			methyl hydrogen phosphate	Not in list	CH4O4P	[O-]P(=O)(O)OC	InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is part of a group assessment	Desmethyl dichlorvos			methyl hydrogen phosphate	Not in list	CH4O4P	[O-]P(=O)(O)OC	InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is part of a group assessment	Desmethyl dichlorvos			methyl hydrogen phosphate	Not in list	CH4O4P	[O-]P(=O)(O)OC	InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is part of a group assessment	Desmethyl dichlorvos			methyl hydrogen phosphate	Not in list	CH4O4P	[O-]P(=O)(O)OC	InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is part of a group assessment	Desmethyl dichlorvos			methyl hydrogen phosphate	Not in list	CH4O4P	[O-]P(=O)(O)OC	InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is part of a group assessment	Desmethyl dichlorvos			methyl hydrogen phosphate	Not in list	CH4O4P	[O-]P(=O)(O)OC	InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is part of a group assessment	Desmethyl dichlorvos			methyl hydrogen phosphate	Not in list	CH4O4P	[O-]P(=O)(O)OC	InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is part of a group assessment	Desmethyl dichlorvos			methyl hydrogen phosphate	Not in list	CH4O4P	[O-]P(=O)(O)OC	InChI=1/CH5O4P/c1-5-6(2,3)4/h1H3,(H2,2,3,4)/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Ambiguous	no information		RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Ambiguous			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)				Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Rat (as animal)				Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CF-1	24	Male/Female	inhalation: unspecified	16.0000000000	h	no	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CF-1	24	Male/Female	oral: unspecified	16.0000000000	h	no	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	24	Male/Female	oral: unspecified	16.0000000000	h	no	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	24	Male/Female	inhalation: unspecified	16.0000000000	h	no	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	24	Male/Female	oral: unspecified	16.0000000000	h	no	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	24	Male/Female	oral: unspecified	16.0000000000	h	no	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	24	Male/Female	inhalation: unspecified	16.0000000000	h	no	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	24	Male/Female	oral: unspecified	16.0000000000	h	no	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CF-1	24	Male/Female	oral: unspecified	16.0000000000	h	no	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CF-1	24	Male/Female	inhalation: unspecified	16.0000000000	h	no	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar	20	Male	oral: gavage			yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	30.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	dermal	72.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	dermal	1.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	dermal	48.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	dermal	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	dermal	6.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	dermal	12.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	3	Male	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344	3	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	House mouse (as animal)	B6C3F1	10	Male/Female	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	House mouse (as animal)	B6C3F1	10	Male/Female	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CF-1	2	No data	oral: unspecified	5.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	NMRI	9	No data	subcutaneous	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	intraperitoneal	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	intraperitoneal	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	intraperitoneal	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	intraperitoneal	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		4	Male	intraperitoneal	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	intraperitoneal	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	intraperitoneal	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		2	Male	intraperitoneal	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		4	Male	intraperitoneal	14.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	12	Male	dermal	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	12	Male	dermal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)		20	Male	inhalation: unspecified	12.0000000000	h	no data	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)		20	Male	inhalation: unspecified	12.0000000000	h	no data	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)		20	Male	inhalation: unspecified	12.0000000000	h	no data	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)		20	Male	inhalation: unspecified	12.0000000000	h	no data	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)		20	Male	inhalation: unspecified	12.0000000000	h	no data	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)		20	Male	inhalation: unspecified	12.0000000000	h	no data	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)		20	Male	inhalation: unspecified	12.0000000000	h	no data	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)		20	Male	inhalation: unspecified	12.0000000000	h	no data	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male	intraperitoneal			yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	CD-1		Male	intraperitoneal			yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Not applicable	Acceptable	House mouse (as animal)		92	Male	intraveneous	96.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Not applicable	Acceptable	House mouse (as animal)		92	Male	intraveneous	24.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Not applicable	Acceptable	House mouse (as animal)		92	Male	intraveneous	72.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Not applicable	Acceptable	House mouse (as animal)		92	Male	intraveneous	48.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: unspecified			no data	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Oregon-R		Male	oral: unspecified			no data	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Oregon-R		Male	oral: unspecified			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	Yes	Acceptable	Drosophila melanogaster (as animal)	Oregon-R		Male	oral: unspecified			yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Drosophila melanogaster (as animal)	Not reported		Female	oral: unspecified			yes	not applicable	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	genome mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Drosophila melanogaster (as animal)	Oregon-R	200	Male/Female	oral: unspecified			yes, concurrent vehicle	not applicable	Positive			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CF-1	4	No data	inhalation: unspecified	5.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	Not reported	12	Female	inhalation: unspecified	8.0000000000	week	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	Not reported	12	Female	oral: unspecified			yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	CF-1		Male	inhalation: unspecified			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CF-1	24	Male/Female	inhalation: unspecified	2.0000000000	h	yes, concurrent no treatment	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	4	Female	oral: unspecified	8.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	8	Male	oral: unspecified	24.0000000000	h	yes, concurrent no treatment	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	8	Male	inhalation: unspecified	2.0000000000	h	yes, concurrent no treatment	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CF-1	12	Male	inhalation: unspecified	2.0000000000	h	yes, concurrent no treatment	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	8	Male	inhalation: unspecified	2.0000000000	h	yes, concurrent no treatment	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	8	Male	oral: unspecified	24.0000000000	h	yes, concurrent no treatment	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CF-1	12	Male	inhalation: unspecified	2.0000000000	h	yes, concurrent no treatment	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	Swiss	8	Male	inhalation: unspecified	16.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	ICR	12	Male	intraperitoneal			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	ICR	9	Male	intraperitoneal			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)		92	Male	intraperitoneal	36.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)		92	Male	intraperitoneal	48.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)		40	Male	oral: drinking water			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)		92	Male	intraperitoneal			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)		92	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)		92	Male	intraperitoneal	72.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)		92	Male	intraperitoneal	12.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)		40	Male	oral: drinking water			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)		8	Male	oral: drinking water			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)		8	Male	oral: drinking water			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)		20	Male	oral: drinking water			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1	3	Male	intraperitoneal			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1	4	Male	intraperitoneal			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	4	Male	intraperitoneal	17.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	8	Male	intraperitoneal	17.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1	4	Male	intraperitoneal			yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Not reported	5	Male	oral: unspecified	20.0000000000	h	yes	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Syrian	6	Female	intraperitoneal	24.0000000000	h	yes, concurrent no treatment	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Dichlorvos	200-547-7	62-73-7	single chemical entity	Component is identical to the substance	Dichlorvos	200-547-7	62-73-7	2,2-dichlorovinyl dimethyl phosphate	Dichlorvos	C4H7Cl2O4P	COP(=O)(OC)OC=C(Cl)Cl	InChI=1/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)		20	Male	intraperitoneal			yes, concurrent no treatment	not applicable	Negative			RMS: Italy	Dichlorvos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance dichlorvos	19Jun2006	2006	doi:10.2903/j.efsa.2006.77r
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Ambiguous			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is identical to the substance	Difenoconazole	601-613-1	119446-68-3	1-[[2-[2-chloro-4-(4-chlorophenoxy)phenyl]-4-methyl-1,3-dioxolan-2-yl]methyl]-1,2,4-triazole	Difenoconazole	C19H17Cl2N3O3	CC1COC(O1)(CN2C=NC=N2)C3=C(C=C(C=C3)OC4=CC=C(C=C4)Cl)Cl	InChI=1S/C19H17Cl2N3O3/c1-13-9-25-19(27-13,10-24-12-22-11-23-24)17-7-6-16(8-18(17)21)26-15-4-2-14(20)3-5-15/h2-8,11-13H,9-10H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-benzoic acid			2-chloro-4-(4-chlorophenoxy)benzoic acid	Difenoconazole-benzoic acid	C13H8Cl2O3	OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2	InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-benzoic acid			2-chloro-4-(4-chlorophenoxy)benzoic acid	Difenoconazole-benzoic acid	C13H8Cl2O3	OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2	InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-benzoic acid			2-chloro-4-(4-chlorophenoxy)benzoic acid	Difenoconazole-benzoic acid	C13H8Cl2O3	OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2	InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-benzoic acid			2-chloro-4-(4-chlorophenoxy)benzoic acid	Difenoconazole-benzoic acid	C13H8Cl2O3	OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2	InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-benzoic acid			2-chloro-4-(4-chlorophenoxy)benzoic acid	Difenoconazole-benzoic acid	C13H8Cl2O3	OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2	InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-benzoic acid			2-chloro-4-(4-chlorophenoxy)benzoic acid	Difenoconazole-benzoic acid	C13H8Cl2O3	OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2	InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-benzoic acid			2-chloro-4-(4-chlorophenoxy)benzoic acid	Difenoconazole-benzoic acid	C13H8Cl2O3	OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2	InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-benzoic acid			2-chloro-4-(4-chlorophenoxy)benzoic acid	Difenoconazole-benzoic acid	C13H8Cl2O3	OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2	InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-benzoic acid			2-chloro-4-(4-chlorophenoxy)benzoic acid	Difenoconazole-benzoic acid	C13H8Cl2O3	OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2	InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-benzoic acid			2-chloro-4-(4-chlorophenoxy)benzoic acid	Difenoconazole-benzoic acid	C13H8Cl2O3	OC(=O)c1ccc(cc1Cl)Oc2ccc(Cl)cc2	InChI=1S/C13H8Cl2O3/c14-8-1-3-9(4-2-8)18-10-5-6-11(13(16)17)12(15)7-10/h1-7H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-ketone			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone	Not in list	C16H11Cl2N3O2	O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-ketone			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone	Not in list	C16H11Cl2N3O2	O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-ketone			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone	Not in list	C16H11Cl2N3O2	O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-ketone			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone	Not in list	C16H11Cl2N3O2	O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-ketone			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone	Not in list	C16H11Cl2N3O2	O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-ketone			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone	Not in list	C16H11Cl2N3O2	O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-ketone			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone	Not in list	C16H11Cl2N3O2	O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-ketone			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone	Not in list	C16H11Cl2N3O2	O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-ketone			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone	Not in list	C16H11Cl2N3O2	O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-ketone			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanone	Not in list	C16H11Cl2N3O2	O=C(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H11Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-alcohol			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol	Not in list	C16H13Cl2N3O2	OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-alcohol			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol	Not in list	C16H13Cl2N3O2	OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-alcohol			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol	Not in list	C16H13Cl2N3O2	OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-alcohol			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol	Not in list	C16H13Cl2N3O2	OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-alcohol			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol	Not in list	C16H13Cl2N3O2	OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-alcohol			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol	Not in list	C16H13Cl2N3O2	OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-alcohol			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol	Not in list	C16H13Cl2N3O2	OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-alcohol			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol	Not in list	C16H13Cl2N3O2	OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-alcohol			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol	Not in list	C16H13Cl2N3O2	OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Difenoconazole-alcohol			1-[2-chloro-4-(4-chlorophenoxy)phenyl]-2-(1H-1,2,4-triazol-1-yl)ethanol	Not in list	C16H13Cl2N3O2	OC(Cn1cncn1)c3ccc(Oc2ccc(Cl)cc2)cc3Cl	InChI=1S/C16H13Cl2N3O2/c17-11-1-3-12(4-2-11)23-13-5-6-14(15(18)7-13)16(22)8-21-10-19-9-20-21/h1-7,9-10,16,22H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Inconclusive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Inconclusive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	30.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Not reported	6	No data	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Inconclusive		no evidence	RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	intraperitoneal	6.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	intraperitoneal	16.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	O-desmethyldimethoate			S-methyl S-[2-(methylamino)-2-oxoethyl] hydrogen phosphorodithioate	Not in list	C4H10NO3PS2	O=P(O)(SC)SCC(=O)NC	InChI=1/C4H10NO3PS2/c1-5-4(6)3-11-9(7,8)10-2/h3H2,1-2H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	CFLP	10	Male	intraperitoneal	48.0000000000	h	yes	not applicable	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	CFLP	10	Male	intraperitoneal	48.0000000000	h	yes	not applicable	Ambiguous			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	CFLP	10	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Ambiguous			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	O-desmethyldimethoate			S-methyl S-[2-(methylamino)-2-oxoethyl] hydrogen phosphorodithioate	Not in list	C4H10NO3PS2	O=P(O)(SC)SCC(=O)NC	InChI=1/C4H10NO3PS2/c1-5-4(6)3-11-9(7,8)10-2/h3H2,1-2H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	CFLP	10	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar	10	Male	oral: gavage	24.0000000000	h	yes	not applicable	Ambiguous			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar	10	Male	oral: gavage	24.0000000000	h	yes	not applicable	Ambiguous			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar	10	Male	oral: gavage			yes	not applicable	Ambiguous			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	Not reported	48.0000000000	h	no	not applicable	Inconclusive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	Not reported	72.0000000000	h	no	not applicable	Inconclusive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	Not reported	24.0000000000	h	no	not applicable	Inconclusive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Syrian	4	Female	intraperitoneal	24.0000000000	h	yes	not applicable	Ambiguous			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar		Male	oral: gavage	4.0000000000	h	no	not applicable	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar		Male	oral: gavage	12.0000000000	h	no	not applicable	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is identical to the substance	Dimethoate	200-480-3	60-51-5	O,O-dimethyl S-[2-(methylamino)-2-oxoethyl] dithiophosphate	Dimethoate	C5H12NO3PS2	CNC(=O)CSP(=S)(OC)OC	InChI=1/C5H12NO3PS2/c1-6-5(7)4-12-10(11,8-2)9-3/h4H2,1-3H3,(H,6,7)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	25	Male	oral: drinking water			yes	not applicable	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mouse spot test	in vivo	Equivalent or similar to	OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test)	Yes	Acceptable	House mouse (as animal)	C57BL		Female	oral: gavage			yes, concurrent vehicle	not applicable	Positive			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	16.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Dimethoate	200-480-3	60-51-5	single chemical entity	Component is a metabolite of the substance	Omethoate	214-197-8	1113-02-6	2-Dimethoxyphosphorylsulfanyl-N-methylacetamide	Omethoate	C5H12NO4PS	CNC(=O)CSP(=O)(OC)OC	InChI=1S/C5H12NO4PS/c1-6-5(7)4-12-11(8,9-2)10-3/h4H2,1-3H3,(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	NMRI		Male	oral: gavage			yes	not applicable	Negative			RMS: The United Kingdom	Dimethoate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance dimethoate	10Jul2013	2013	doi:10.2903/j.efsa.2013.3233
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	12	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is identical to the substance	Teflubenzuron		83121-18-0	N-[(3,5-dichloro-2,4-difluorophenyl)carbamoyl]-2,6-difluorobenzamide	Teflubenzuron	C14H6Cl2F4N2O2	O=C(NC(NC2=C(F)C(Cl)=C(F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C14H6Cl2F4N2O2/c15-5-4-8(12(20)10(16)11(5)19)21-14(24)22-13(23)9-6(17)2-1-3-7(9)18/h1-4H,(H2,21,22,23,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	12	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluoroaniline	617-438-9	83121-15-7	3,5-dichloro-2,4-difluoroaniline	Not in list	C6H3Cl2F2N	C1=C(C(=C(C(=C1Cl)F)Cl)F)N	InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluoroaniline	617-438-9	83121-15-7	3,5-dichloro-2,4-difluoroaniline	Not in list	C6H3Cl2F2N	C1=C(C(=C(C(=C1Cl)F)Cl)F)N	InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluoroaniline	617-438-9	83121-15-7	3,5-dichloro-2,4-difluoroaniline	Not in list	C6H3Cl2F2N	C1=C(C(=C(C(=C1Cl)F)Cl)F)N	InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluoroaniline	617-438-9	83121-15-7	3,5-dichloro-2,4-difluoroaniline	Not in list	C6H3Cl2F2N	C1=C(C(=C(C(=C1Cl)F)Cl)F)N	InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluoroaniline	617-438-9	83121-15-7	3,5-dichloro-2,4-difluoroaniline	Not in list	C6H3Cl2F2N	C1=C(C(=C(C(=C1Cl)F)Cl)F)N	InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluoroaniline	617-438-9	83121-15-7	3,5-dichloro-2,4-difluoroaniline	Not in list	C6H3Cl2F2N	C1=C(C(=C(C(=C1Cl)F)Cl)F)N	InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluoroaniline	617-438-9	83121-15-7	3,5-dichloro-2,4-difluoroaniline	Not in list	C6H3Cl2F2N	C1=C(C(=C(C(=C1Cl)F)Cl)F)N	InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluoroaniline	617-438-9	83121-15-7	3,5-dichloro-2,4-difluoroaniline	Not in list	C6H3Cl2F2N	C1=C(C(=C(C(=C1Cl)F)Cl)F)N	InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluoroaniline	617-438-9	83121-15-7	3,5-dichloro-2,4-difluoroaniline	Not in list	C6H3Cl2F2N	C1=C(C(=C(C(=C1Cl)F)Cl)F)N	InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluoroaniline	617-438-9	83121-15-7	3,5-dichloro-2,4-difluoroaniline	Not in list	C6H3Cl2F2N	C1=C(C(=C(C(=C1Cl)F)Cl)F)N	InChI=1S/C6H3Cl2F2N/c7-2-1-3(11)6(10)4(8)5(2)9/h1H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluorophenylurea			1-(3,5-dichloro-2,4-difluorophenyl)urea	Not in list	C7H4Cl2F2N2O	Clc1cc(NC(N)=O)c(F)c(Cl)c1F	InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluorophenylurea			1-(3,5-dichloro-2,4-difluorophenyl)urea	Not in list	C7H4Cl2F2N2O	Clc1cc(NC(N)=O)c(F)c(Cl)c1F	InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluorophenylurea			1-(3,5-dichloro-2,4-difluorophenyl)urea	Not in list	C7H4Cl2F2N2O	Clc1cc(NC(N)=O)c(F)c(Cl)c1F	InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluorophenylurea			1-(3,5-dichloro-2,4-difluorophenyl)urea	Not in list	C7H4Cl2F2N2O	Clc1cc(NC(N)=O)c(F)c(Cl)c1F	InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluorophenylurea			1-(3,5-dichloro-2,4-difluorophenyl)urea	Not in list	C7H4Cl2F2N2O	Clc1cc(NC(N)=O)c(F)c(Cl)c1F	InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluorophenylurea			1-(3,5-dichloro-2,4-difluorophenyl)urea	Not in list	C7H4Cl2F2N2O	Clc1cc(NC(N)=O)c(F)c(Cl)c1F	InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluorophenylurea			1-(3,5-dichloro-2,4-difluorophenyl)urea	Not in list	C7H4Cl2F2N2O	Clc1cc(NC(N)=O)c(F)c(Cl)c1F	InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluorophenylurea			1-(3,5-dichloro-2,4-difluorophenyl)urea	Not in list	C7H4Cl2F2N2O	Clc1cc(NC(N)=O)c(F)c(Cl)c1F	InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluorophenylurea			1-(3,5-dichloro-2,4-difluorophenyl)urea	Not in list	C7H4Cl2F2N2O	Clc1cc(NC(N)=O)c(F)c(Cl)c1F	InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Teflubenzuron		83121-18-0	single chemical entity	Component is a metabolite of the substance	3,5-dichloro-2,4-difluorophenylurea			1-(3,5-dichloro-2,4-difluorophenyl)urea	Not in list	C7H4Cl2F2N2O	Clc1cc(NC(N)=O)c(F)c(Cl)c1F	InChI=1/C7H4Cl2F2N2O/c8-2-1-3(13-7(12)14)6(11)4(9)5(2)10/h1H,(H3,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Teflubenzuron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance teflubenzuron	15Jan2009	2009	doi:10.2903/j.efsa.2009.184r
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	No guideline available	Not reported	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	No guideline available	Not reported	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Schizosaccharomyces pombe (as organism)	Not reported			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Schizosaccharomyces pombe (as organism)	Not reported			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent no treatment	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent no treatment	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent no treatment	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent no treatment	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	30	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	30	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	30	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is identical to the substance	Glufosinate-ammonium	278-636-5	77182-82-2	ammonium (2RS)-2-amino-4-(methylphosphinato)butyric acid	Glufosinate-ammonium	C5H12NO4P.H3N	CP(=O)(CCC(C(=O)[O-])N)O.[NH4+]	InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8;/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10);1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	N-acetyl-glufosinate		73634-73-8	2-acetamido-4-[hydroxy(methyl)phosphoryl]butanoic acid	Not in list	C7H14NO5P	CC(=O)NC(CCP(=O)(C)O)C(=O)O	InChI=1S/C7H14NO5P/c1-5(9)8-6(7(10)11)3-4-14(2,12)13/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Schizosaccharomyces pombe (as organism)				Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Schizosaccharomyces pombe (as organism)				Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	6.0000000000	h	yes	not applicable	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	3-metylphosphinico-propionic acid			3-[hydroxy(methyl)phosphoryl]propanoic acid	Not in list	C4H9O4P	O=C(O)CCP(C)(=O)O	InChI=1/C4H9O4P/c1-9(7,8)3-2-4(5)6/h2-3H2,1H3,(H,5,6)(H,7,8)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Positive			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Glufosinate-ammonium	278-636-5	77182-82-2	single chemical entity	Component is a metabolite of the substance	2-methylphosphinico-acetic acid			[hydroxy(methyl)phosphoryl]acetic acid	Not in list	C3H7O4P	O=C(O)CP(C)(=O)O	InChI=1/C3H7O4P/c1-8(6,7)2-3(4)5/h2H2,1H3,(H,4,5)(H,6,7)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Sweden	Glufosinate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance glufosinate	30Mar2012	2012	doi:10.2903/j.efsa.2012.2609
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is identical to the substance	Halosulfuron-methyl	600-130-3	100784-20-1	methyl 3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-1-methylpyrazole-4-carboxylate	Halosulfuron methyl	C13H15ClN6O7S	CN1C(=C(C(=N1)Cl)C(=O)OC)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C13H15ClN6O7S/c1-20-10(8(9(14)18-20)11(21)27-4)28(23,24)19-13(22)17-12-15-6(25-2)5-7(16-12)26-3/h5H,1-4H3,(H2,15,16,17,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid			3-chloro-1-methyl-5-sulfamoyl-1H-pyrazole-4-carboxylic acid	Not in list	C5H6ClN3O4S	OC(=O)c1c(n(C)nc1Cl)S(N)(=O)=O	InChI=1/C5H6ClN3O4S/c1-9-4(14(7,12)13)2(5(10)11)3(6)8-9/h1H3,(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Halosulfuron-methyl	600-130-3	100784-20-1	single chemical entity	Component is a metabolite of the substance	methyl 3-chloro-5-[(4,6-dimethoxy-2-pyrimidinyl)amino]-1-methyl-1H-pyrazole-4-carboxylate			3-chloro-5-[(4,6-dimethoxypyrimidin-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylic acid	Not in list	C12H13lN4O4	OC(=O)c2c(Cc1nc(OC)cc(OC)n1)n(C)nc2Cl	InChI=1/C12H13ClN4O4/c1-17-6(10(12(18)19)11(13)16-17)4-7-14-8(20-2)5-9(15-7)21-3/h5H,4H2,1-3H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Halosulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance halosulfuron (evaluated variant halosulfuron-methyl)	06Dec2012	2012	doi:10.2903/j.efsa.2012.2987
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is identical to the substance	Tetraconazole	407-760-6	112281-77-3	1-[2-(2,4-Dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]-1,2, 4-triazole	Tetraconazole	C13H11Cl2F4N3O	C1=CC(=C(C=C1Cl)Cl)C(CN2C=NC=N2)COC(C(F)F)(F)F	InChI=1S/C13H11Cl2F4N3O/c14-9-1-2-10(11(15)3-9)8(4-22-7-20-6-21-22)5-23-13(18,19)12(16)17/h1-3,6-8,12H,4-5H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	2-(2,4-Dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid			2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Not in list	C11H9Cl2N3O2	OC(=O)C(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1S/C11H9Cl2N3O2/c12-7-1-2-8(10(13)3-7)9(11(17)18)4-16-6-14-5-15-16/h1-3,5-6,9H,4H2,(H,17,18)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid			[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid	Not in list	C13H11Cl2F2N3O3	O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid			[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid	Not in list	C13H11Cl2F2N3O3	O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid			[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid	Not in list	C13H11Cl2F2N3O3	O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid			[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid	Not in list	C13H11Cl2F2N3O3	O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid			[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid	Not in list	C13H11Cl2F2N3O3	O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid			[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid	Not in list	C13H11Cl2F2N3O3	O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid			[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid	Not in list	C13H11Cl2F2N3O3	O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid			[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid	Not in list	C13H11Cl2F2N3O3	O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid			[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid	Not in list	C13H11Cl2F2N3O3	O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid			[2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propoxy](difluoro)acetic acid	Not in list	C13H11Cl2F2N3O3	O=C(O)C(F)(F)OCC(Cn1cncn1)c2ccc(Cl)cc2Cl	InChI=1/C13H11Cl2F2N3O3/c14-9-1-2-10(11(15)3-9)8(4-20-7-18-6-19-20)5-23-13(16,17)12(21)22/h1-3,6-8H,4-5H2,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Positive			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Positive			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is identical to the substance	Fluopicolide		239110-15-7	2,6-dichloro-N-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide	Fluopicolide	C14H8Cl3F3N2O	C1=CC(=C(C(=C1)Cl)C(=O)NCC2=C(C=C(C=N2)C(F)(F)F)Cl)Cl	InChI=1S/C14H8Cl3F3N2O/c15-8-2-1-3-9(16)12(8)13(23)22-6-11-10(17)4-7(5-21-11)14(18,19)20/h1-5H,6H2,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Not reported	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Not reported	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-Dichlorobenzamide	217-918-4	2008-58-4	2,6-dichlorobenzamide	Not in list	C7H5Cl2NO	C1=CC(=C(C(=C1)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3H,(H2,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Not reported	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Chloro-5-trifluoromethylpyridine-2-carboxylic acid			3-chloro-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(O)=O)C(F)(F)F	InChI=1S/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	2,6-dichloro-3-hydroxybenzamide		22818-74-2	2,6-dichloro-3-hydroxybenzamide	Not in list	C7H5Cl2NO2	C1=CC(=C(C(=C1O)Cl)C(=O)N)Cl	InChI=1S/C7H5Cl2NO2/c8-3-1-2-4(11)6(9)5(3)7(10)12/h1-2,11H,(H2,10,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Methylsulfinyl-5-trifluoromethylpyridine-2-carboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)pyridine-2-carboxylic acid	Not in list	C8H6F3NO3S	OC(=O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Positive			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Positive			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	6	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-Sulfo-5-trifluoromethyl pyridine-2-carboxylic acid			2-sulfo-4-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O5S	OS(=O)(=O)c1cc(ccc1C(=O)O)C(F)(F)F	InChI=1S/C8H5F3O5S/c9-8(10,11)4-1-2-5(7(12)13)6(3-4)17(14,15)16/h1-3H,(H,12,13)(H,14,15,16)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male	intraperitoneal	24.0000000000		yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	Not reported	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Fluopicolide		239110-15-7	single chemical entity	Component is a metabolite of the substance	3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol			3-(methylsulfonyl)-5-(trifluoromethyl)pyridin-2-ol	Not in list	C7H6F3NO3S	O=S(C)(=O)c1cc(cnc1O)C(F)(F)F	InChI=1/C7H6F3NO3S/c1-15(13,14)5-2-4(7(8,9)10)3-11-6(5)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	Not reported	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fluopicolide	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fluopicolide	09Jul2009	2009	doi:10.2903/j.efsa.2009.299r
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is identical to the substance	Tembotrione	608-879-8	335104-84-2	2-[2-chloro-4-methylsulfonyl-3-(2,2,2-trifluoroethoxymethyl)benzoyl]cyclohexane-1,3-dione	Tembotrione	C17H16ClF3O6S	CS(=O)(=O)C1=C(C(=C(C=C1)C(=O)C2C(=O)CCCC2=O)Cl)COCC(F)(F)F	InChI=1S/C17H16ClF3O6S/c1-28(25,26)13-6-5-9(15(18)10(13)7-27-8-17(19,20)21)16(24)14-11(22)3-2-4-12(14)23/h5-6,14H,2-4,7-8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid			2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]benzoic acid	Not in list	C11H10ClF3O5S	OC(=O)c1ccc(c(COCC(F)(F)F)c1Cl)S(C)(=O)=O	InChI=1/C11H10ClF3O5S/c1-21(18,19)8-3-2-6(10(16)17)9(12)7(8)4-20-5-11(13,14)15/h2-3H,4-5H2,1H3,(H,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-{2-Chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy) methyl]benzoyl}-4,6-dihydroxycyclohexane-1,3-dione			2-({2-chloro-4-(methylsulfonyl)-3-[(2,2,2-trifluoroethoxy)methyl]phenyl}carbonyl)-4,6-dihydroxycyclohexane-1,3-dione	Tembotrione metabolite M5 (Dihydroxy-tembotrione)	C17H16ClF3O8S	O=C1C(C(=O)C(O)CC1O)C(=O)c2ccc(c(COCC(F)(F)F)c2Cl)S(C)(=O)=O	InChI=1/C17H16ClF3O8S/c1-30(27,28)11-3-2-7(13(18)8(11)5-29-6-17(19,20)21)14(24)12-15(25)9(22)4-10(23)16(12)26/h2-3,9-10,12,22-23H,4-6H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	2-Chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid			2-chloro-3-(hydroxymethyl)-4-(methylsulfonyl)benzoic acid	Not in list	C9H9ClO5S	OC(=O)c1ccc(c(CO)c1Cl)S(C)(=O)=O	InChI=1/C9H9ClO5S/c1-16(14,15)7-3-2-5(9(12)13)8(10)6(7)4-11/h2-3,11H,4H2,1H3,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione			6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione	Not in list	C17H15F3O6S	CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F	InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione			6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione	Not in list	C17H15F3O6S	CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F	InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione			6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione	Not in list	C17H15F3O6S	CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F	InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione			6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione	Not in list	C17H15F3O6S	CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F	InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione			6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione	Not in list	C17H15F3O6S	CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F	InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione			6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione	Not in list	C17H15F3O6S	CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F	InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione			6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione	Not in list	C17H15F3O6S	CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F	InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione			6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione	Not in list	C17H15F3O6S	CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F	InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent no treatment	without	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione			6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione	Not in list	C17H15F3O6S	CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F	InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Tembotrione	608-879-8	335104-84-2	single chemical entity	Component is a metabolite of the substance	6-(Methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione			6-(methylsulfonyl)-5-[(2,2,2-trifluoroethoxy)methyl]-3,4-dihydro-1H-xanthene-1,9(2H)-dione	Not in list	C17H15F3O6S	CS(=O)(=O)c2ccc1C(=O)C=3C(=O)CCCC=3Oc1c2COCC(F)(F)F	InChI=1/C17H15F3O6S/c1-27(23,24)13-6-5-9-15(22)14-11(21)3-2-4-12(14)26-16(9)10(13)7-25-8-17(18,19)20/h5-6H,2-4,7-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent no treatment	with	Negative			RMS: Austria	Tembotrione	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tembotrione	15Mar2013	2013	doi:10.2903/j.efsa.2013.3131
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is identical to the substance	Fluxapyroxad		907204-31-3	3-(Difluoromethyl)-1-methyl-N-[2-(3,4,5-trifluorophenyl)phenyl]pyrazole-4-carboxamide	Fluxapyroxad	C18H12F5N3O	CN1C=C(C(=N1)C(F)F)C(=O)NC2=CC=CC=C2C3=CC(=C(C(=C3)F)F)F	InChI=1S/C18H12F5N3O/c1-26-8-11(16(25-26)17(22)23)18(27)24-14-5-3-2-4-10(14)9-6-12(19)15(21)13(20)7-9/h2-8,17H,1H3,(H,24,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Fluxapyroxad		907204-31-3	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide			3-(difluoromethyl)-1-(b-Dglucopyranosyloxy)-N-(3',4',5'-trifluorobiphenyl-2-yl)-1H-pyrazole-4-carboxamide	Not in list	C23H20F5N3O7	Fc1cc(cc(F)c1F)c4ccccc4NC(=O)c2cn(nc2C(F)F)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O	InChI=1S/C23H20F5N3O7/c24-12-5-9(6-13(25)16(12)26)10-3-1-2-4-14(10)29-22(36)11-7-31(30-17(11)21(27)28)38-23-20(35)19(34)18(33)15(8-32)37-23/h1-7,15,18-21,23,32-35H,8H2,(H,29,36)/t15-,18-,19+,20-,23+/m1/s1	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: unspecified	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	BAS 700 F (Fluxapyroxad)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluxapyroxad (BAS 700 F)	27Jan2012	2012	doi:10.2903/j.efsa.2012.2522
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: unspecified	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Ambiguous			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	48	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	48	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	48	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2-carboxylic acid		59337-97-2	3-sulfamoylthiophene-2-carboxylic acid	Not in list	C5H5NO4S2	C1=CSC(=C1S(=O)(=O)N)C(=O)O	InChI=1S/C5H5NO4S2/c6-12(9,10)3-1-2-11-4(3)5(7)8/h1-2H,(H,7,8)(H2,6,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	616-675-5	79277-67-1	3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylic acid	Not in list	C11H11N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)O	InChI=1S/C11H11N5O6S2/c1-5-12-9(15-11(13-5)22-2)14-10(19)16-24(20,21)6-3-4-23-7(6)8(17)18/h3-4H,1-2H3,(H,17,18)(H2,12,13,14,15,16,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-methyl-1,3,5-triazine-2-yl)urea			1-(4-acetyl-6-methyl-1,3,5-triazin-2-yl)urea	Not in list	C7H9N5O2	O=C(N)Nc1nc(C)nc(n1)C(C)=O	InChI=1/C7H9N5O2/c1-3(13)5-9-4(2)10-7(11-5)12-6(8)14/h1-2H3,(H3,8,9,10,11,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	28	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	thieno[2,3-d][1,2]thiazol-3(2H)-one 1,1-dioxide			thieno[2,3-d]isothiazol-3(2H)-one 1,1-dioxide	Not in list	C5H3NO3S2	O=S2(=O)NC(=O)c1sccc12	InChI=1/C5H3NO3S2/c7-5-4-3(1-2-10-4)11(8,9)6-5/h1-2H,(H,6,7)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	28	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid			3-{[(4-hydroxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamoyl}thiophene-2-carboxylic acid	Not in list	C10H9N5O6S2	OC(=O)c1sccc1S(=O)(=O)NC(=O)Nc2nc(C)nc(O)n2	InChI=1/C10H9N5O6S2/c1-4-11-8(13-9(18)12-4)14-10(19)15-23(20,21)5-2-3-22-6(5)7(16)17/h2-3H,1H3,(H,16,17)(H3,11,12,13,14,15,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	House mouse (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	5	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	5	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is identical to the substance	Thiamethoxam	428-650-4	153719-23-4	(NE)-N-[3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3, 5-oxadiazinan-4-ylidene]nitramide	Thiamethoxam	C8H10ClN5O3S	CN\1COCN(/C1=N/[N+](=O)[O-])CC2=CN=C(S2)Cl	InChI=1S/C8H10ClN5O3S/c1-12-4-17-5-13(8(12)11-14(15)16)3-6-2-10-7(9)18-6/h2H,3-5H2,1H3/b11-8+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	5	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	Clothianidin	433-460-1	210880-92-5	1-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-methyl-3-nitroguanidine	Clothianidin	C6H8ClN5O2S	CN=C(NCC1=CN=C(S1)Cl)N[N+](=O)[O-]	InChI=1S/C6H8ClN5O2S/c1-8-6(11-12(13)14)10-3-4-2-9-5(7)15-4/h2H,3H2,1H3,(H2,8,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	3-(2-chlorothiazol-5-ylmethyl)-5-methyl-[1,3,5]oxadiazinan-4-ylideneamin			3-[(2-chloro-1,3-thiazol-5-yl)methyl]-5-methyl-1,3,5-oxadiazinan-4-imine	Not in list	C8H11ClN4OS	Clc2ncc(CN1COCN(C)C1=N)s2	InChI=1/C8H11ClN4OS/c1-12-4-14-5-13(8(12)10)3-6-2-11-7(9)15-6/h2,10H,3-5H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiamethoxam	2001	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Positive			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male	oral: gavage	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male	oral: gavage	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley		Male	oral: gavage	2.0000000000	h	no data	not applicable	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Thiamethoxam	428-650-4	153719-23-4	single chemical entity	Component is a metabolite of the substance	NOA 459602				Not in list				organic	no structure			DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley		Male	oral: gavage	16.0000000000	h	no data	not applicable	Negative			RMS: Spain	Thiamethoxam (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance thiamethoxam	16Jan2013	2013	doi:10.2903/j.efsa.2013.3067
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mouse spot test	in vivo	Equivalent or similar to	OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Not reported			subcutaneous			no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported			subcutaneous			no data	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	Not reported			Not reported			no data	no data	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Not reported			Not reported			no data	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	Not reported			no data	not applicable	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	Not reported			no data	not applicable	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2-aminobenzimidazole	213-280-6	934-32-7	1H-benzimidazol-2-amine	Not in list	C7H7N3	C1=CC=C2C(=C1)NC(=N2)N	InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2-aminobenzimidazole	213-280-6	934-32-7	1H-benzimidazol-2-amine	Not in list	C7H7N3	C1=CC=C2C(=C1)NC(=N2)N	InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2-aminobenzimidazole	213-280-6	934-32-7	1H-benzimidazol-2-amine	Not in list	C7H7N3	C1=CC=C2C(=C1)NC(=N2)N	InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2-aminobenzimidazole	213-280-6	934-32-7	1H-benzimidazol-2-amine	Not in list	C7H7N3	C1=CC=C2C(=C1)NC(=N2)N	InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2-aminobenzimidazole	213-280-6	934-32-7	1H-benzimidazol-2-amine	Not in list	C7H7N3	C1=CC=C2C(=C1)NC(=N2)N	InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2-aminobenzimidazole	213-280-6	934-32-7	1H-benzimidazol-2-amine	Not in list	C7H7N3	C1=CC=C2C(=C1)NC(=N2)N	InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2-aminobenzimidazole	213-280-6	934-32-7	1H-benzimidazol-2-amine	Not in list	C7H7N3	C1=CC=C2C(=C1)NC(=N2)N	InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2-aminobenzimidazole	213-280-6	934-32-7	1H-benzimidazol-2-amine	Not in list	C7H7N3	C1=CC=C2C(=C1)NC(=N2)N	InChI=1S/C7H7N3/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H3,8,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is a metabolite of the substance	2,3-phenazine-diamine	211-512-0	655-86-7	phenazine-2,3-diamine	Not in list	C12H10N4	C1=CC=C2C(=C1)N=C3C=C(C(=CC3=N2)N)N	InChI=1S/C12H10N4/c13-7-5-11-12(6-8(7)14)16-10-4-2-1-3-9(10)15-11/h1-6H,13-14H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
1,4-Dimethylnaphthalene	209-335-9	571-58-4	single chemical entity	Component is identical to the substance	1,4-Dimethylnaphthalene	209-335-9	571-58-4	1,4-dimethylnaphthalene	Not in list	C12H12	Cc1ccc(C)c2ccccc12	InChI=1/C12H12/c1-9-7-8-10(2)12-6-4-3-5-11(9)12/h3-8H,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The Netherlands	1,4-Dimethylnaphthalene (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 1,4-dimethylnaphthalene.	18Oct2013	2013	doi:10.2903/j.efsa.2013.3229
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Inconclusive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Inconclusive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Inconclusive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Inconclusive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	8	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	8	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	8	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mouse spot test	in vivo	Equivalent or similar to	OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test)	Yes	Acceptable	House mouse (as animal)	C57BL		Female	oral: feed			yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	Rat (as animal)			Male	oral: gavage			yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	Rat (as animal)	Not reported		Male	intraperitoneal			yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	Rat (as animal)	Not reported		Male	oral: gavage			yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	3	Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	8	Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Folpet	205-087-0	133-07-3	single chemical entity	Component is identical to the substance	Folpet	205-088-6	133-07-3	2-(Trichloromethylsulfanyl)isoindole-1,3-dione	Folpet	C9H4Cl3NO2S	C1=CC=C2C(=C1)C(=O)N(C2=O)SC(Cl)(Cl)Cl	InChI=1S/C9H4Cl3NO2S/c10-9(11,12)16-13-7(14)5-3-1-2-4-6(5)8(13)15/h1-4H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	8	Female	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Folpet (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance folpet	31Aug2009	2009	doi:10.2903/j.efsa.2009.297r
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is identical to the substance	Florasulam	604-488-1	145701-23-1	N-(2,6-difluorophenyl)-8-fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Florasulam	C12H8F3N5O3S	COC1=NC=C(C2=NC(=NN21)S(=O)(=O)NC3=C(C=CC=C3F)F)F	InChI=1S/C12H8F3N5O3S/c1-23-12-16-5-8(15)10-17-11(18-20(10)12)24(21,22)19-9-6(13)3-2-4-7(9)14/h2-5,19H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Florasulam	1999	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-difluorophenyl)-8-fluoro-5-oxo-5,6-dihydro[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide			N-(2,6-difluorophenyl)-8-fluoro-5-hydroxy[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide	Not in list	C11H6F3N5O3S	Fc3cccc(F)c3NS(=O)(=O)c1nc2c(F)cnc(O)n2n1	InChI=1/C11H6F3N5O3S/c12-5-2-1-3-6(13)8(5)18-23(21,22)10-16-9-7(14)4-15-11(20)19(9)17-10/h1-4,18H,(H,15,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoyl-1H-1,2,4-triazole-5-carboxylic acid		313963-93-8	5-sulfamoyl-1H-1,2,4-triazole-3-carboxylic acid	Not in list	C3H4N4O4S	C1(=NNC(=N1)S(=O)(=O)N)C(=O)O	InChI=1S/C3H4N4O4S/c4-12(10,11)3-5-1(2(8)9)6-7-3/h(H,8,9)(H2,4,10,11)(H,5,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
Florasulam	604-488-1	145701-23-1	single chemical entity	Component is a metabolite of the substance	1H-1,2,4-triazole-3-sulfonamide		89517-96-4	1H-1,2,4-triazole-5-sulfonamide	Not in list	C2H4N4O2S	C1=NNC(=N1)S(=O)(=O)N	InChI=1S/C2H4N4O2S/c3-9(7,8)2-4-1-5-6-2/h1H,(H2,3,7,8)(H,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Poland	Florasulam (RAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance florasulam	13Jan2015	2015	doi:10.2903/j.efsa.2015.3984
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Positive			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Positive			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Positive	no information		RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Positive			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylbenzoquinone		363-03-1	2-phenylcyclohexa-2,5-diene-1,4-dione	Not in list	C12H8O2	C1=CC=C(C=C1)C2=CC(=O)C=CC2=O	InChI=1S/C12H8O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	no data	Negative			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
2-Phenylphenol	201-993-5	90-43-7	single chemical entity	Component is a metabolite of the substance	Phenylhydroquinone		1079-21-6	2-phenylbenzene-1,4-diol	Not in list	C12H10O2	C1=CC=C(C=C1)C2=C(C=CC(=C2)O)O	InChI=1S/C12H10O2/c13-10-6-7-12(14)11(8-10)9-4-2-1-3-5-9/h1-8,13-14H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	not applicable	Positive			RMS: Spain	Ortho-phenylphenol	2007	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2-phenylphenol	06Mar2009	2009	doi:10.2903/j.efsa.2009.217r
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)				Not reported			no data	no data	Positive			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium chloride	231-208-1	7446-70-0	trichloroalumane	Not in list	AlCl3	[Al](Cl)(Cl)Cl	InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium chloride	231-208-1	7446-70-0	trichloroalumane	Not in list	AlCl3	[Al](Cl)(Cl)Cl	InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium oxide	618-619-5	1344-28-1	dialuminum;oxygen(2-)	Not in list	Al2O3	[O-2].[O-2].[O-2].[Al+3].[Al+3]	InChI=1S/2Al.3O/q2*+3;3*-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium oxide	618-619-5	1344-28-1	dialuminum;oxygen(2-)	Not in list	Al2O3	[O-2].[O-2].[O-2].[Al+3].[Al+3]	InChI=1S/2Al.3O/q2*+3;3*-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)				Not reported			no data	no data	Positive			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium sulphate	233-135-0	10043-01-3	Dialuminum trisulfate	Aluminium sulphate	Al2O12S3	[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[Al+3]	InChI=1S/2Al.3H2O4S/c;;3*1-5(2,3)4/h;;3*(H2,1,2,3,4)/q2*+3;;;/p-6	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)				Not reported			no data	no data	Positive			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Aluminium ammonium sulphate dodecahydrate	232-055-3	7784-26-1	single chemical entity	Component is part of a group but not included in the group assessment	Aluminium chloride	231-208-1	7446-70-0	trichloroalumane	Not in list	AlCl3	[Al](Cl)(Cl)Cl	InChI=1S/Al.3ClH/h;3*1H/q+3;;;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal			no data	not applicable	Positive			RMS: Portugal	Aluminium ammonium sulphate (Final Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance aluminium ammonium sulfate (approved as aluminium ammonium sulphate)	15Mar2012	2012	doi:10.2903/j.efsa.2012.2491
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)				Not reported			yes	with	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)				Not reported			yes	without	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Inconclusive		no evidence	RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Inconclusive		no evidence	RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Inconclusive		no evidence	RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	6.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is identical to the substance	Benfuracarb		82560-54-1	ethyl 3-[[(2,2-dimethyl-3H-1-benzofuran-7-yl)oxycarbonyl-methylamino]sulfanyl-propan-2-ylamino]propanoate	Benfuracarb	C20H30N2O5S	CCOC(=O)CCN(C(C)C)SN(C)C(=O)OC1=CC=CC2=C1OC(C2)(C)C	InChI=1S/C20H30N2O5S/c1-7-25-17(23)11-12-22(14(2)3)28-21(6)19(24)26-16-10-8-9-15-13-20(4,5)27-18(15)16/h8-10,14H,7,11-13H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Benfuracarb	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-3,7-diol		17781-15-6	2,2-dimethyl-3H-1-benzofuran-3,7-diol	Not in list	C10H12O3	CC1(C(C2=C(O1)C(=CC=C2)O)O)C	InChI=1S/C10H12O3/c1-10(2)9(12)6-4-3-5-7(11)8(6)13-10/h3-5,9,11-12H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	no data	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-3,7-diol		17781-15-6	2,2-dimethyl-3H-1-benzofuran-3,7-diol	Not in list	C10H12O3	CC1(C(C2=C(O1)C(=CC=C2)O)O)C	InChI=1S/C10H12O3/c1-10(2)9(12)6-4-3-5-7(11)8(6)13-10/h3-5,9,11-12H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	no data	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-3,7-diol		17781-15-6	2,2-dimethyl-3H-1-benzofuran-3,7-diol	Not in list	C10H12O3	CC1(C(C2=C(O1)C(=CC=C2)O)O)C	InChI=1S/C10H12O3/c1-10(2)9(12)6-4-3-5-7(11)8(6)13-10/h3-5,9,11-12H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	no data	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-3,7-diol		17781-15-6	2,2-dimethyl-3H-1-benzofuran-3,7-diol	Not in list	C10H12O3	CC1(C(C2=C(O1)C(=CC=C2)O)O)C	InChI=1S/C10H12O3/c1-10(2)9(12)6-4-3-5-7(11)8(6)13-10/h3-5,9,11-12H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	no data	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benfuracarb		82560-54-1	single chemical entity	Component is a metabolite of the substance	2,2-dimethyl-2,3-dihydro-1-benzofuran-3,7-diol		17781-15-6	2,2-dimethyl-3H-1-benzofuran-3,7-diol	Not in list	C10H12O3	CC1(C(C2=C(O1)C(=CC=C2)O)O)C	InChI=1S/C10H12O3/c1-10(2)9(12)6-4-3-5-7(11)8(6)13-10/h3-5,9,11-12H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	no data	Negative			RMS: Belgium	Benfuracarb (Original version July 2004, revised in August 2008)	2008	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance benfuracarb	08Apr2009	2009	doi:10.2903/j.efsa.2009.239r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Benthiavalicarb-isopropyl		177406-68-7	single chemical entity	Component is identical to the substance	Benthiavalicarb-isopropyl		177406-68-7	Propan-2-yl N-[(2R)-1-[[(1R)-1-(6-fluoro-1, 3-benzothiazol-2-yl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate	Benthiavalicarb isopropyl	C18H24FN3O3S	C[C@H](C1=NC2=C(S1)C=C(C=C2)F)NC(=O)[C@@H](C(C)C)NC(=O)OC(C)C	InChI=1S/C18H24FN3O3S/c1-9(2)15(22-18(24)25-10(3)4)16(23)20-11(5)17-21-13-7-6-12(19)8-14(13)26-17/h6-11,15H,1-5H3,(H,20,23)(H,22,24)/t11-,15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Benthiavalicarb-isopropyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance benthiavalicarb	01Aug2007	2007	doi:10.2903/j.efsa.2007.107r
Bromuconazole		116255-48-2	single chemical entity	Component is a metabolite of the substance	1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole			1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole	Not in list	C13H11Cl2N3O	Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3	InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is a metabolite of the substance	1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole			1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole	Not in list	C13H11Cl2N3O	Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3	InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is a metabolite of the substance	1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole			1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole	Not in list	C13H11Cl2N3O	Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3	InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is a metabolite of the substance	1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole			1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole	Not in list	C13H11Cl2N3O	Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3	InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is a metabolite of the substance	1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole			1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole	Not in list	C13H11Cl2N3O	Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3	InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is a metabolite of the substance	1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole			1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole	Not in list	C13H11Cl2N3O	Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3	InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is a metabolite of the substance	1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole			1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole	Not in list	C13H11Cl2N3O	Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3	InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is a metabolite of the substance	1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole			1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole	Not in list	C13H11Cl2N3O	Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3	InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is a metabolite of the substance	1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole			1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole	Not in list	C13H11Cl2N3O	Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3	InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Bromuconazole		116255-48-2	single chemical entity	Component is a metabolite of the substance	1-{[(2RS)-2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole			1-{[2-(2,4-dichlorophenyl)-2,5-dihydrofuran-2-yl]methyl}-1H-1,2,4-triazole	Not in list	C13H11Cl2N3O	Clc1cc(Cl)c(cc1)C2(C=CCO2)Cn3cncn3	InChI=1/C13H11Cl2N3O/c14-10-2-3-11(12(15)6-10)13(4-1-5-19-13)7-18-9-16-8-17-18/h1-4,6,8-9H,5,7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Bromuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bromuconazole	27Aug2010	2010	doi:10.2903/j.efsa.2010.1704
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	42.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Carbosulfan (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Carbosulfan	259-565-9	55285-14-8	single chemical entity	Component is identical to the substance	Carbosulfan	259-565-9	55285-14-8	2,3-Dihydro-2,2-dimethyl-7-benzofuranyl ((dibutylamino)thio)methylcarbamate	Carbosulfan	C20H32N2O3S	CCCCN(CCCC)SN(C)C(=O)Oc1cccc2CC(C)(C)Oc12	InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	18.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Carbosulfan (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbosulfan	05Nov2009	2009	doi:10.2903/j.efsa.2009.1354
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Diquat	220-433-0	85-00-7	single chemical entity	Component is identical to the substance	Diquat	220-433-0	85-00-7	6,7-dihydrodipyrido[1,2-b:1',2'-e]pyrazine-5,8-diium	Diquat	C12H12N2+2	C1C[N+]2=CC=CC=C2C3=CC=CC=[N+]31	InChI=1S/C12H12N2/c1-3-7-13-9-10-14-8-4-2-6-12(14)11(13)5-1/h1-8H,9-10H2/q+2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	oral: gavage			no data	not applicable	Negative			RMS: The United Kingdom	Diquat	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance diquat	27Nov2015	2015	doi:10.2903/j.efsa.2015.4308
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Clofentezine (Addendum1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Clofentezine (Addendum1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Clofentezine (Addendum1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: The United Kingdom	Clofentezine (Addendum1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Clofentezine (Addendum1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Clofentezine (Addendum1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Clofentezine (Addendum1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Clofentezine (Addendum1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: The United Kingdom	Clofentezine (Addendum1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Clofentezine	277-728-2	74115-24-5	single chemical entity	Component is identical to the substance	Clofentezine	277-728-2	74115-24-5	3,6-bis(2-chlorophenyl)-1,2,4,5-tetrazine	Clofentezine	C14H8Cl2N4	Clc3ccccc3c1nnc(nn1)c2ccccc2Cl	InChI=1S/C14H8Cl2N4/c15-11-7-3-1-5-9(11)13-17-19-14(20-18-13)10-6-2-4-8-12(10)16/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Clofentezine (Addendum1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance clofentezine	20Jul2009	2009	doi:10.2903/j.efsa.2009.269r
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Cyproconazole		94361-06-5	single chemical entity	Component is a metabolite of the substance	5-(4-chloro-phenyl)-3,5-dihydroxy-4-methyl-6-[1,2,4]triazol-1-yl-hexanoic acid			5-(4-chlorophenyl)-3,5-dihydroxy-4-methyl-6-(1H-1,2,4-triazol-1-yl)hexanoic acid	Not in list	C15H18ClN3O4	OC(Cn1cncn1)(C(C)C(O)CC(=O)O)c2ccc(Cl)cc2	InChI=1/C15H18ClN3O4/c1-10(13(20)6-14(21)22)15(23,7-19-9-17-8-18-19)11-2-4-12(16)5-3-11/h2-5,8-10,13,20,23H,6-7H2,1H3,(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Cyproconazole	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyproconazole	25Nov2010	2010	doi:10.2903/j.efsa.2010.1897
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1536			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	PQ37			Not reported			yes	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	PQ37			Not reported			yes	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	PQ37			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	PQ37			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	no data	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	no data	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	spleen cells			Not reported			no data	no data	Positive			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	House mouse (as animal)	spleen cells			Not reported			no data	no data	Positive			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	no data	Positive			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Human (as organism)	fibroblast			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Human (as organism)	fibroblast			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Human (as organism)	fibroblast			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Human (as organism)	fibroblast			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	fibroblast			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	fibroblast			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	fibroblast			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	fibroblast			Not reported			no data	with	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	fibroblast			Not reported			no data	with	Positive			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	CHO			Not reported			no data	no data	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	CHO			Not reported			no data	no data	Positive			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	Hep G2 human cell line			Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)				Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)				Not reported			no data	without	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Sprague-Dawley		Male/Female	oral: gavage			no data	not applicable	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal			no data	not applicable	Positive			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Drosophila melanogaster (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Dicamba	217-635-6	1918-00-9	single chemical entity	Component is identical to the substance	Dicamba	217-635-6	1918-00-9	3,6-dichloro-2-methoxybenzoic acid	Dicamba	C8H6Cl2O3	COc1c(Cl)ccc(Cl)c1C(=O)O	InChI=1/C8H6Cl2O3/c1-13-7-5(10)3-2-4(9)6(7)8(11)12/h2-3H,1H3,(H,11,12)	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Sprague-Dawley		Male	Not reported			no data	not applicable	Positive			RMS: Denmark	Dicamba (Revised draft assessment report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dicamba	14Jan2011	2011	doi:10.2903/j.efsa.2011.1965
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: the United Kingdom	Diflufenican (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Diflufenican		83164-33-4	single chemical entity	Component is identical to the substance	Diflufenican		83164-33-4	N-(2,4-difluorophenyl)-2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxamide	Diflufenican	C19H11F5N2O2	C1=CC(=CC(=C1)OC2=C(C=CC=N2)C(=O)NC3=C(C=C(C=C3)F)F)C(F)(F)F	InChI=1S/C19H11F5N2O2/c20-12-6-7-16(15(21)10-12)26-17(27)14-5-2-8-25-18(14)28-13-4-1-3-11(9-13)19(22,23)24/h1-10H,(H,26,27)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: the United Kingdom	Diflufenican (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance diflufenican	14Feb2008	2008	doi:10.2903/j.efsa.2008.122r
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Dodine	219-459-5	2439-10-3	single chemical entity	Component is identical to the substance	Dodine	219-459-5	2439-10-3	1-dodecylguanidine acetate	Dodine	C13H29N3.C2H4O2	CCCCCCCCCCCCNC(=N)N.CC(=O)O	InChI=1/C13H29N3.C2H4O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-13(14)15;1-2(3)4/h2-12H2,1H3,(H4,14,15,16);1H3,(H,3,4)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Portugal	Dodine (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dodine	21Jun2010	2010	doi:10.2903/j.efsa.2010.1631
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is identical to the substance	Thifensulfuron-methyl	616-673-4	79277-27-3	methyl 3-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]thiophene-2-carboxylate	Thifensulfuron-methyl	C12H13N5O6S2	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=C(SC=C2)C(=O)OC	InChI=1S/C12H13N5O6S2/c1-6-13-10(16-12(14-6)23-3)15-11(19)17-25(20,21)7-4-5-24-8(7)9(18)22-2/h4-5H,1-3H3,(H2,13,14,15,16,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	no data	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA1530			Not reported			no data	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA1530			Not reported			no data	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	no data	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Not reported			Not reported			no data	without	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	gene mutation	in vitro gene mutation assay in fungi	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Aspergillus nidulans (as organism)	Not reported			Not reported			no data	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR		No data	oral: gavage			no data	not applicable	Positive		no evidence	RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR		No data	intraperitoneal			no data	not applicable	Negative		no evidence	RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is part of a group but not included in the group assessment	Thiophanate-methyl	245-740-7	23564-05-8	methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate	Thiophanate-methyl	C12H14N4O4S2	COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC	InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is part of a group but not included in the group assessment	Thiophanate-methyl	245-740-7	23564-05-8	methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate	Thiophanate-methyl	C12H14N4O4S2	COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC	InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No data	Acceptable	Other				Not reported			no data	no data	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	no data	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Not reported		Female	oral: unspecified			yes	not applicable	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Rat (as animal)	Not reported		Male	oral: unspecified	48.0000000000	h	yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Not reported		Male	oral: unspecified			yes	not applicable	Negative			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Sprague-Dawley		Male	Not reported	24.0000000000	h	yes	not applicable	Positive			RMS: Germany	Carbendazim	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is identical to the substance	Carbendazim	234-232-0	10605-21-7	methyl 1H-benzimidazol-2-ylcarbamate	Carbendazim	C9H9N3O2	N(C(=O)OC)C1=Nc2ccccc2N1	InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	No data	Acceptable	House mouse (as animal)	Not reported	6	Male	oral: gavage	28.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Carbendazim, Benomyl, Thiophanate-methyl (Addendum)	2002	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		Male	Not reported			yes, concurrent vehicle	not applicable	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		Male	Not reported			yes, concurrent vehicle	not applicable	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			no data	no data	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is part of a group assessment	2,4-D dimethyl amine salt	217-915-8	2008-39-1	2-(2,4-dichlorophenoxy)acetic acid;N-methylmethanamine	Not in list	C10H13Cl2NO3	CNC.C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3.C2H7N/c9-5-1-2-7(6(10)3-5)13-4-8(11)12;1-3-2/h1-3H,4H2,(H,11,12);3H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)				Not reported			yes	no data	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is part of a group assessment	2,4-D dimethyl amine salt	217-915-8	2008-39-1	2-(2,4-dichlorophenoxy)acetic acid;N-methylmethanamine	Not in list	C10H13Cl2NO3	CNC.C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3.C2H7N/c9-5-1-2-7(6(10)3-5)13-4-8(11)12;1-3-2/h1-3H,4H2,(H,11,12);3H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)				Not reported			yes	no data	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Human (as organism)				Not reported			yes	no data	Negative			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Human (as organism)				Not reported			yes	no data	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	CHO			Not reported			no data	no data	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is part of a group assessment	2,4-D dimethyl amine salt	217-915-8	2008-39-1	2-(2,4-dichlorophenoxy)acetic acid;N-methylmethanamine	Not in list	C10H13Cl2NO3	CNC.C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3.C2H7N/c9-5-1-2-7(6(10)3-5)13-4-8(11)12;1-3-2/h1-3H,4H2,(H,11,12);3H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	no data	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	no data	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is part of a group assessment	2,4-D dimethyl amine salt	217-915-8	2008-39-1	2-(2,4-dichlorophenoxy)acetic acid;N-methylmethanamine	Not in list	C10H13Cl2NO3	CNC.C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3.C2H7N/c9-5-1-2-7(6(10)3-5)13-4-8(11)12;1-3-2/h1-3H,4H2,(H,11,12);3H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	CHO			Not reported			yes	no data	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	oral: gavage	48.0000000000	h	no data	not applicable	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	oral: gavage	24.0000000000	h	no data	not applicable	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	oral: gavage	48.0000000000	h	no data	not applicable	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	oral: gavage	24.0000000000	h	no data	not applicable	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	no data	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-D	202-361-1	94-75-7	single chemical entity	Component is identical to the substance	2,4-D	202-361-1	94-75-7	(2,4-dichlorophenoxy)acetic acid	2,4-D	C8H6Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCC(=O)O	InChI=1S/C8H6Cl2O3/c9-5-1-2-7(6(10)3-5)13-4-8(11)12/h1-3H,4H2,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	no data	Positive			RMS: Greece - CoRMS: Poland	2,4-D (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D	11Sep2014	2014	doi:10.2903/j.efsa.2014.3812
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)				Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)				Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)				Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is a metabolite of the substance	2,4-dichlorophenol	204-429-6	120-83-2	2,4-dichlorophenol	Not in list	C6H4Cl2O	C1=CC(=C(C=C1Cl)Cl)O	InChI=1S/C6H4Cl2O/c7-4-1-2-6(9)5(8)3-4/h1-3,9H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)				Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
2,4-DB	202-366-9	94-82-6	single chemical entity	Component is identical to the substance	2,4-DB	202-366-9	94-82-6	4-(2,4-dichlorophenoxy)butanoic acid	2,4-DB (sum of 2,4-DB, its salts, its esters and its conjugates, expressed as 2,4-DB)	C10H10Cl2O3	C1=CC(=C(C=C1Cl)Cl)OCCCC(=O)O	InChI=1S/C10H10Cl2O3/c11-7-3-4-9(8(12)6-7)15-5-1-2-10(13)14/h3-4,6H,1-2,5H2,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	Yes	Acceptable	Human (as organism)				Not reported			yes	no data	Negative			RMS: Belgium - CoRMS: Greece	2,4-DB	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance 2,4-DB	31May2016	2016	doi:10.2903/j.efsa.2016.4500
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Azoxystrobin		131860-33-8	single chemical entity	Component is a metabolite of the substance	2-[6-(2-cyanophenoxy)pyrimidin-4-yloxy]benzoic acid			2-{[6-(2-cyanophenoxy)pyrimidin-4-yl]oxy}benzoic acid	Not in list	C18H11N3O4	O=C(O)c3ccccc3Oc2cc(Oc1ccccc1C#N)ncn2	InChI=1/C18H11N3O4/c19-10-12-5-1-3-7-14(12)24-16-9-17(21-11-20-16)25-15-8-4-2-6-13(15)18(22)23/h1-9,11H,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Czech Republic	Azoxystrobin (Final Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance azoxystrobin	15Apr2010	2010	doi:10.2903/j.efsa.2010.1542
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	Methyl N-(malonyl)-N-(2,6-xylyl)-D-alaninate			3-{(2,6-dimethylphenyl)[(2R)-1-methoxy-1-oxopropan-2-yl]amino}-3-oxopropanoic acid	Not in list	C15H19NO5	C[C@@H](N(C(=O)CC(=O)O)c1c(C)cccc1C)C(=O)OC	InChI=1/C15H19NO5/c1-9-6-5-7-10(2)14(9)16(11(3)15(20)21-4)12(17)8-13(18)19/h5-7,11H,8H2,1-4H3,(H,18,19)/t11-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	Not reported	68.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(2RS)-1-methoxy-1-oxo-2-propanyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-methoxy-1-oxopropan-2-yl)amino]-3-methylbenzoic acid	Not in list		CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)OC	InChI=1/C15H17NO7/c1-8-5-4-6-10(14(20)21)13(8)16(9(2)15(22)23-3)11(17)7-12(18)19/h4-6,9H,7H2,1-3H3,(H,18,19)(H,20,21)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	Not reported	44.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	Not reported	68.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Benalaxyl-M		98243-83-5	single chemical entity	Component is a metabolite of the substance	2-{(Carboxyacetyl)[(1RS)-1-carboxyethyl]amino}-3-methylbenzoic acid			2-[(carboxyacetyl)(1-carboxyethyl)amino]-3-methylbenzoic acid	Not in list	C14H15NO7	CC(N(C(=O)CC(=O)O)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H15NO7/c1-7-4-3-5-9(14(21)22)12(7)15(8(2)13(19)20)10(16)6-11(17)18/h3-5,8H,6H2,1-2H3,(H,17,18)(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	Not reported	44.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Portugal	Benalaxyl-M (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance benalaxyl-M.	04Apr2013	2013	doi:10.2903/j.efsa.2013.3148
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Bupirimate	255-391-2	41483-43-6	single chemical entity	Component is identical to the substance	Bupirimate	255-391-2	41483-43-6	5-butyl-2-(ethylamino)-6-methylpyrimidin-4-yl dimethylsulfamate	Bupirimate	C13H24N4O3S	O=S(OC1=C(CCCC)C(C)=NC(NCC)=N1)(N(C)C)=O	InChI=1S/C13H24N4O3S/c1-6-8-9-11-10(3)15-13(14-7-2)16-12(11)20-21(18,19)17(4)5/h6-9H2,1-5H3,(H,14,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Bupirimate (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bupirimate	05Oct2010	2010	doi:10.2903/j.efsa.2010.1786
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione			5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione	Not in list	C12H14N2O2S	CC(C)N2C(=O)SCN(c1ccccc1)C2=O	InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione			5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione	Not in list	C12H14N2O2S	CC(C)N2C(=O)SCN(c1ccccc1)C2=O	InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione			5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione	Not in list	C12H14N2O2S	CC(C)N2C(=O)SCN(c1ccccc1)C2=O	InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione			5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione	Not in list	C12H14N2O2S	CC(C)N2C(=O)SCN(c1ccccc1)C2=O	InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione			5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione	Not in list	C12H14N2O2S	CC(C)N2C(=O)SCN(c1ccccc1)C2=O	InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione			5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione	Not in list	C12H14N2O2S	CC(C)N2C(=O)SCN(c1ccccc1)C2=O	InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione			5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione	Not in list	C12H14N2O2S	CC(C)N2C(=O)SCN(c1ccccc1)C2=O	InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione			5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione	Not in list	C12H14N2O2S	CC(C)N2C(=O)SCN(c1ccccc1)C2=O	InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione			5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione	Not in list	C12H14N2O2S	CC(C)N2C(=O)SCN(c1ccccc1)C2=O	InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione			5-phenyl-3-(propan-2-yl)-1,3,5-thiadiazinane-2,4-dione	Not in list	C12H14N2O2S	CC(C)N2C(=O)SCN(c1ccccc1)C2=O	InChI=1/C12H14N2O2S/c1-9(2)14-11(15)13(8-17-12(14)16)10-6-4-3-5-7-10/h3-7,9H,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide	Not in list	C15H23N3O2	O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C	InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide	Not in list	C15H23N3O2	O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C	InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide	Not in list	C15H23N3O2	O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C	InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide	Not in list	C15H23N3O2	O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C	InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide	Not in list	C15H23N3O2	O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C	InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide	Not in list	C15H23N3O2	O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C	InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide	Not in list	C15H23N3O2	O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C	InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide	Not in list	C15H23N3O2	O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C	InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide	Not in list	C15H23N3O2	O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C	InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidic diamide	Not in list	C15H23N3O2	O=C(Nc1ccccc1)N(C(=O)NC(C)(C)C)C(C)C	InChI=1/C15H23N3O2/c1-11(2)18(14(20)17-15(3,4)5)13(19)16-12-9-7-6-8-10-12/h6-11H,1-5H3,(H,16,19)(H,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	1-phenyl-3-propan-2-ylurea		19895-44-4	1-phenyl-3-propan-2-ylurea	Not in list	C10H14N2O	CC(C)NC(=O)NC1=CC=CC=C1	InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	1-phenyl-3-propan-2-ylurea		19895-44-4	1-phenyl-3-propan-2-ylurea	Not in list	C10H14N2O	CC(C)NC(=O)NC1=CC=CC=C1	InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	1-phenyl-3-propan-2-ylurea		19895-44-4	1-phenyl-3-propan-2-ylurea	Not in list	C10H14N2O	CC(C)NC(=O)NC1=CC=CC=C1	InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	1-phenyl-3-propan-2-ylurea		19895-44-4	1-phenyl-3-propan-2-ylurea	Not in list	C10H14N2O	CC(C)NC(=O)NC1=CC=CC=C1	InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	1-phenyl-3-propan-2-ylurea		19895-44-4	1-phenyl-3-propan-2-ylurea	Not in list	C10H14N2O	CC(C)NC(=O)NC1=CC=CC=C1	InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	1-phenyl-3-propan-2-ylurea		19895-44-4	1-phenyl-3-propan-2-ylurea	Not in list	C10H14N2O	CC(C)NC(=O)NC1=CC=CC=C1	InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	1-phenyl-3-propan-2-ylurea		19895-44-4	1-phenyl-3-propan-2-ylurea	Not in list	C10H14N2O	CC(C)NC(=O)NC1=CC=CC=C1	InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	1-phenyl-3-propan-2-ylurea		19895-44-4	1-phenyl-3-propan-2-ylurea	Not in list	C10H14N2O	CC(C)NC(=O)NC1=CC=CC=C1	InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	1-phenyl-3-propan-2-ylurea		19895-44-4	1-phenyl-3-propan-2-ylurea	Not in list	C10H14N2O	CC(C)NC(=O)NC1=CC=CC=C1	InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	1-phenyl-3-propan-2-ylurea		19895-44-4	1-phenyl-3-propan-2-ylurea	Not in list	C10H14N2O	CC(C)NC(=O)NC1=CC=CC=C1	InChI=1S/C10H14N2O/c1-8(2)11-10(13)12-9-6-4-3-5-7-9/h3-8H,1-2H3,(H2,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	Not in list	C15H23N3OS	O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	Not in list	C15H23N3OS	O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	Not in list	C15H23N3OS	O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	Not in list	C15H23N3OS	O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	Not in list	C15H23N3OS	O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	Not in list	C15H23N3OS	O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	Not in list	C15H23N3OS	O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	Not in list	C15H23N3OS	O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	Not in list	C15H23N3OS	O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Buprofezin		69327-76-0	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide			N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	Not in list	C15H23N3OS	O=C(Nc1ccccc1)N(C(=S)NC(C)(C)C)C(C)C	N-tert-butyl-N'-phenyl-N-propan-2-yldicarbonimidothioic diamide	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Buprofezin (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance buprofezin	03Jun2010	2010	doi:10.2903/j.efsa.2010.1624
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2E)-3-{2-Chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}acrylic acid			(2E)-3-{2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}prop-2-enoic acid	Not in list	C13H9ClF3N3O3	O=C(O)/C=C/c1cc(c(F)cc1Cl)N2N=C(C)N(C2=O)C(F)F	InChI=1/C13H9ClF3N3O3/c1-6-18-20(13(23)19(6)12(16)17)10-4-7(2-3-11(21)22)8(14)5-9(10)15/h2-5,12H,1H3,(H,21,22)/b3-2+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	(2RS)-2-Chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			2-chloro-3-{2-chloro-5-[4-(difluoromethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C12H8Cl2F3N3O3	O=C(O)C(Cl)Cc1cc(c(F)cc1Cl)N2N=CN(C2=O)C(F)F	InChI=1/C12H8Cl2F3N3O3/c13-6-3-8(15)9(2-5(6)1-7(14)10(21)22)20-12(23)19(4-18-20)11(16)17/h2-4,7,11H,1H2,(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	4-(Difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one			4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C4H5F2N3O	O=C1NN=C(C)N1C(F)F	InChI=1/C4H5F2N3O/c1-2-7-8-4(10)9(2)3(5)6/h3H,1H3,(H,8,10)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C11H11ClF3N3O4	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C11H11ClF3N3O4	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C11H11ClF3N3O4	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C11H11ClF3N3O4	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C11H11ClF3N3O4	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C11H11ClF3N3O4	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C11H11ClF3N3O4	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C11H11ClF3N3O4	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C11H11ClF3N3O4	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Carfentrazone-ethyl	603-291-8	128639-02-1	single chemical entity	Component is a metabolite of the substance	3-{2-Chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid			3-{2-chloro-5-[4-(difluoromethyl)-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl}propanoic acid	Not in list	C11H11ClF3N3O4	O=C(O)CCc1cc(c(F)cc1Cl)N2N=C(CO)N(C2=O)C(F)F	InChI=1/C13H11ClF3N3O4/c14-7-4-8(15)9(3-6(7)1-2-11(22)23)20-13(24)19(12(16)17)10(5-21)18-20/h3-4,12,21H,1-2,5H2,(H,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: France	Carfentrazone-ethyl	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance carfentrazone-ethyl	30Aug2016	2016	doi:10.2903/j.efsa.2016.4569
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfinyl)propyl]pentanedioic acid			3-[2-(ethylsulfinyl)propyl]pentanedioic acid	Not in list	C10H18O5S	CCS(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O5S/c1-3-16(15)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid			3-[2-(ethylsulfonyl)propyl]pentanedioic acid	Not in list	C10H18O6S	CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid			3-[2-(ethylsulfonyl)propyl]pentanedioic acid	Not in list	C10H18O6S	CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid			3-[2-(ethylsulfonyl)propyl]pentanedioic acid	Not in list	C10H18O6S	CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid			3-[2-(ethylsulfonyl)propyl]pentanedioic acid	Not in list	C10H18O6S	CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid			3-[2-(ethylsulfonyl)propyl]pentanedioic acid	Not in list	C10H18O6S	CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid			3-[2-(ethylsulfonyl)propyl]pentanedioic acid	Not in list	C10H18O6S	CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid			3-[2-(ethylsulfonyl)propyl]pentanedioic acid	Not in list	C10H18O6S	CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid			3-[2-(ethylsulfonyl)propyl]pentanedioic acid	Not in list	C10H18O6S	CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid			3-[2-(ethylsulfonyl)propyl]pentanedioic acid	Not in list	C10H18O6S	CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Clethodim		99129-21-2	single chemical entity	Component is a metabolite of the substance	3-[(2RS)-2-(ethylsulfonyl)propyl]pentanedioic acid			3-[2-(ethylsulfonyl)propyl]pentanedioic acid	Not in list	C10H18O6S	CCS(=O)(=O)C(C)CC(CC(=O)O)CC(=O)O	InChI=1/C10H18O6S/c1-3-17(15,16)7(2)4-8(5-9(11)12)6-10(13)14/h7-8H,3-6H2,1-2H3,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Clethodim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance clethodim	21Oct2011	2011	doi:10.2903/j.efsa.2011.2417
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cyantraniliprole		736994-63-1	single chemical entity	Component is a metabolite of the substance	3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide			3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide	Not in list	C9H6BrClN4O	NC(=O)c2cc(Br)nn2c1ncccc1Cl	InChI=1/C9H6BrClN4O/c10-7-4-6(8(12)16)15(14-7)9-5(11)2-1-3-13-9/h1-4H,(H2,12,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom - CoRMS: France	Cyantraniliprole (Final Addendum)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cyantraniliprole	09Sep2014	2014	doi:10.2903/j.efsa.2014.3814
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(3-thianyl)glutaric acid S-dioxide			3-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O6S	O=S1(=O)CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O6S/c11-9(12)4-8(5-10(13)14)7-2-1-3-17(15,16)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-3-(3-thianyl)glutaric acid S-dioxide			2-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)-2-hydroxybutanedioic acid	Not in list	C9H14O7S	O=S1(=O)CCCC(C1)C(O)(CC(=O)O)C(=O)O	InChI=1/C9H14O7S/c10-7(11)4-9(14,8(12)13)6-2-1-3-17(15,16)5-6/h6,14H,1-5H2,(H,10,11)(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-3-(3-thianyl)glutaric acid S-dioxide			2-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)-2-hydroxybutanedioic acid	Not in list	C9H14O7S	O=S1(=O)CCCC(C1)C(O)(CC(=O)O)C(=O)O	InChI=1/C9H14O7S/c10-7(11)4-9(14,8(12)13)6-2-1-3-17(15,16)5-6/h6,14H,1-5H2,(H,10,11)(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-3-(3-thianyl)glutaric acid S-dioxide			2-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)-2-hydroxybutanedioic acid	Not in list	C9H14O7S	O=S1(=O)CCCC(C1)C(O)(CC(=O)O)C(=O)O	InChI=1/C9H14O7S/c10-7(11)4-9(14,8(12)13)6-2-1-3-17(15,16)5-6/h6,14H,1-5H2,(H,10,11)(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-hydroxy-3-(3-thianyl)glutaric acid S-dioxide			2-(1,1-dioxidotetrahydro-2H-thiopyran-3-yl)-2-hydroxybutanedioic acid	Not in list	C9H14O7S	O=S1(=O)CCCC(C1)C(O)(CC(=O)O)C(=O)O	InChI=1/C9H14O7S/c10-7(11)4-9(14,8(12)13)6-2-1-3-17(15,16)5-6/h6,14H,1-5H2,(H,10,11)(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cycloxydim		101205-02-1	single chemical entity	Component is a metabolite of the substance	3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid			3-(1-oxidotetrahydro-2H-thiopyran-3-yl)pentanedioic acid	Not in list	C10H16O5S	O=S1CCCC(C1)C(CC(=O)O)CC(=O)O	InChI=1/C10H16O5S/c11-9(12)4-8(5-10(13)14)7-2-1-3-16(15)6-7/h7-8H,1-6H2,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Cycloxydim (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance cycloxydim	08Jul2010	2010	doi:10.2903/j.efsa.2010.1669
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Cyhalofop-butyl	601-817-0	122008-85-9	single chemical entity	Component is a metabolite of the substance	4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid			4-{4-[(1R)-1-carboxyethoxy]phenoxy}-3-fluorobenzoic acid	Cyhalofop-butyl (sum of cyhalofop butyl and its free acids)	C16H13FO6	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ccc(cc2F)C(=O)O	InChI=1/C16H13FO6/c1-9(15(18)19)22-11-3-5-12(6-4-11)23-14-7-2-10(16(20)21)8-13(14)17/h2-9H,1H3,(H,18,19)(H,20,21)/t9-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy - CoRMS: Austria	Cyhalofop-butyl (RAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance cyhalofop (variant evaluated cyhalofop-butyl)	30Jan2015	2015	doi: 10.2903/j.efsa.2015.3943
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Dazomet	208-576-7	533-74-4	single chemical entity	Component is identical to the substance	Dazomet	208-576-7	533-74-4	3,5-dimethyl-1,3,5-thiadiazinane-2-thione	Dazomet	C5H10N2S2	CN1CSC(=S)N(C)C1	InChI=1/C5H10N2S2/c1-6-3-7(2)5(8)9-4-6/h3-4H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Dazomet (Revised)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance dazomet	07Oct2010	2010	doi:10.2903/j.efsa.2010.1833
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Geraniol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Geraniol	269-750-6	106-24-1	single chemical entity	Component is identical to the substance	Geraniol	269-750-6	106-24-1	(2E)-3,7-dimethylocta-2,6-dien-1-ol	geraniol	C10H18O	CC(=CCCC(=CCO)C)C	InChI=1S/C10H18O/c1-9(2)5-4-6-10(3)7-8-11/h5,7,11H,4,6,8H2,1-3H3/b10-7+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Geraniol (Final Addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance geraniol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2915
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Ethofumesate	247-525-3	26225-79-6	single chemical entity	Component is identical to the substance	Ethofumesate	247-525-3	26225-79-6	(2-ethoxy-3,3-dimethyl-2H-1-benzofuran-5-yl) methanesulfonate	Ethofumesate	C13H18O5S	CCOC1C(C2=C(O1)C=CC(=C2)OS(=O)(=O)C)(C)C	InChI=1S/C13H18O5S/c1-5-16-12-13(2,3)10-8-9(18-19(4,14)15)6-7-11(10)17-12/h6-8,12H,5H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Denmark	Ethofumesate	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance ethofumesate	19Jan2016	2016	doi:10.2903/j.efsa.2016.4374
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	Swiss	24	Male	oral: unspecified			yes	not applicable	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	Swiss		Female	oral: unspecified			yes	not applicable	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	16	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	16	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent no treatment	without	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imazaquin		81335-37-7	single chemical entity	Component is identical to the substance	Imazaquin		81335-37-7	2-(4-Methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)quinoline-3-carboxylic acid	Imazaquin	C17H17N3O3	CC(C)C1(C(=O)NC(=N1)C2=NC3=CC=CC=C3C=C2C(=O)O)C	InChI=1S/C17H17N3O3/c1-9(2)17(3)16(23)19-14(20-17)13-11(15(21)22)8-10-6-4-5-7-12(10)18-13/h4-9H,1-3H3,(H,21,22)(H,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male	oral: gavage	5.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Imazaquin	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazaquin	07Jan2011	2011	doi:10.2903/j.efsa.2011.1968
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Positive			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Positive			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Positive			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Positive			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Not reported		No data	oral: unspecified	6.0000000000	h	no data	not applicable	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Not reported		No data	oral: unspecified	24.0000000000	h	no data	not applicable	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Not reported		No data	oral: unspecified	48.0000000000	h	no data	not applicable	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	oral: unspecified	72.0000000000	h	no data	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	oral: unspecified	24.0000000000	h	no data	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Not reported		No data	oral: unspecified	1.0000000000	D	no data	not applicable	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is identical to the substance	Imidacloprid		138261-41-3	(2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine	Imidacloprid	C9H10ClN5O2	ClC(C=C2)=NC=C2CN1/C(NCC1)=N/[N+]([O-])=O	InChI=1S/C9H10ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-2,5H,3-4,6H2,(H,11,13)	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI		Male	oral: unspecified			no data	not applicable	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Inconclusive			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Inconclusive			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, historical	with	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, historical	without	Negative			RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Ipconazole		125225-28-7	single chemical entity	Component is identical to the substance	Ipconazole		125225-28-7	2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Ipconazole	C18H24ClN3O	OC1(CN3N=CN=C3)C(CC2=CC=C(Cl)C=C2)CCC1C(C)C	InChI=1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Ipconazole	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ipconazole.	09Apr2013	2013	doi:10.2903/j.efsa.2013.3181
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	18.0000000000	h	yes	not applicable	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Wistar	16	Male	oral: feed	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	6	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is identical to the substance	Kresoxim-methyl		143390-89-0	methyl (2E)-2-methoxyimino-2-[2-[(2-methylphenoxy)methyl]phenyl]acetate	Kresoxim-methyl	C18H19NO4	CC1=CC=CC=C1OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC	InChI=1S/C18H19NO4/c1-13-8-4-7-11-16(13)23-12-14-9-5-6-10-15(14)17(19-22-3)18(20)21-2/h4-11H,12H2,1-3H3/b19-17+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	6	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid			(2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO	InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid			(2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO	InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid			(2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO	InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid			(2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO	InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid			(2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO	InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid			(2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO	InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid			(2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO	InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid			(2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO	InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid			(2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO	InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-(2-{[2-(hydroxymethyl)phenoxy] methyl}phenyl)(methoxyimino)acetic acid			(2E)-(2-{[2-(hydroxymethyl)phenoxy]methyl}phenyl)(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccccc1CO	InChI=1/C17H17NO5/c1-22-18-16(17(20)21)14-8-4-2-7-13(14)11-23-15-9-5-3-6-12(15)10-19/h2-9,19H,10-11H2,1H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid			(2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C	InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid			(2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C	InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid			(2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C	InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid			(2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C	InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid			(2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C	InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid			(2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C	InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid			(2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C	InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid			(2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C	InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid			(2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C	InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(2E)-{2-[(4-hydroxy-2-methylphenoxy) methyl]phenyl}(methoxyimino)acetic acid			(2E)-{2-[(4-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	OC(=O)\C(=N\OC)c2ccccc2COc1ccc(O)cc1C	InChI=1/C17H17NO5/c1-11-9-13(19)7-8-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid			(2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C	InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid			(2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C	InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid			(2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C	InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid			(2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C	InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid			(2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C	InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid			(2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C	InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid			(2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C	InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid			(2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C	InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid			(2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C	InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	2-[2-(5-hydroxy-2-methylphenoxymethyl)phenyl]-2-methoxyiminoacetic acid			(2E)-{2-[(5-hydroxy-2-methylphenoxy)methyl]phenyl}(methoxyimino)ethanoic acid	Not in list	C17H17NO5	O=C(O)\C(=N\OC)c2ccccc2COc1cc(O)ccc1C	InChI=1/C17H17NO5/c1-11-7-8-13(19)9-15(11)23-10-12-5-3-4-6-14(12)16(17(20)21)18-22-2/h3-9,19H,10H2,1-2H3,(H,20,21)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	intraperitoneal	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar	9	Female	oral: feed	7.0000000000	D	yes	not applicable	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar	9	Female	oral: feed	7.0000000000	D	yes	not applicable	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is identical to the substance	Iprovalicarb	604-209-3		propan-2-yl N-[(2R)-3-methyl-1-[1-(4-methylphenyl)ethylamino]-1-oxobutan-2-yl]carbamate	Iprovalicarb	C18H28N2O3	CC1=CC=C(C=C1)C(C)NC(=O)C(C(C)C)NC(=O)OC(C)C	InChI=1S/C18H28N2O3/c1-11(2)16(20-18(22)23-12(3)4)17(21)19-14(6)15-9-7-13(5)8-10-15/h7-12,14,16H,1-6H3,(H,19,21)(H,20,22)/t14?,16-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar	9	Female	oral: feed	7.0000000000	D	yes	not applicable	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Not reported	9	Male	oral: gavage	18.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male	oral: gavage	48.0000000000	h	yes	not applicable	Positive		no evidence	RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male	oral: gavage	24.0000000000	h	yes	not applicable	Positive		no evidence	RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: gavage	24.0000000000	h	yes	not applicable	Positive		no evidence	RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Wistar	25	Male	oral: feed	19.0000000000	week	yes	not applicable	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Iprovalicarb	604-209-3		single chemical entity	Component is a metabolite of the substance	(1RS)-1-(4-methylphenyl)ethanamine			(1RS)-1-(4-methylphenyl)ethanamine	Not in list	C9H13N	Cc1ccc(cc1)C(N)C	InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is a metabolite of the substance	(1RS)-1-(4-methylphenyl)ethanamine			(1RS)-1-(4-methylphenyl)ethanamine	Not in list	C9H13N	Cc1ccc(cc1)C(N)C	InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is a metabolite of the substance	(1RS)-1-(4-methylphenyl)ethanamine			(1RS)-1-(4-methylphenyl)ethanamine	Not in list	C9H13N	Cc1ccc(cc1)C(N)C	InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is a metabolite of the substance	(1RS)-1-(4-methylphenyl)ethanamine			(1RS)-1-(4-methylphenyl)ethanamine	Not in list	C9H13N	Cc1ccc(cc1)C(N)C	InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is a metabolite of the substance	(1RS)-1-(4-methylphenyl)ethanamine			(1RS)-1-(4-methylphenyl)ethanamine	Not in list	C9H13N	Cc1ccc(cc1)C(N)C	InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is a metabolite of the substance	(1RS)-1-(4-methylphenyl)ethanamine			(1RS)-1-(4-methylphenyl)ethanamine	Not in list	C9H13N	Cc1ccc(cc1)C(N)C	InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is a metabolite of the substance	(1RS)-1-(4-methylphenyl)ethanamine			(1RS)-1-(4-methylphenyl)ethanamine	Not in list	C9H13N	Cc1ccc(cc1)C(N)C	InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is a metabolite of the substance	(1RS)-1-(4-methylphenyl)ethanamine			(1RS)-1-(4-methylphenyl)ethanamine	Not in list	C9H13N	Cc1ccc(cc1)C(N)C	InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is a metabolite of the substance	(1RS)-1-(4-methylphenyl)ethanamine			(1RS)-1-(4-methylphenyl)ethanamine	Not in list	C9H13N	Cc1ccc(cc1)C(N)C	InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Iprovalicarb	604-209-3		single chemical entity	Component is a metabolite of the substance	(1RS)-1-(4-methylphenyl)ethanamine			(1RS)-1-(4-methylphenyl)ethanamine	Not in list	C9H13N	Cc1ccc(cc1)C(N)C	InChI=1/C9H13N/c1-7-3-5-9(6-4-7)8(2)10/h3-6,8H,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Iprovalicarb	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iprovalicarb	14Apr2015	2015	doi:10.2903/j.efsa.2015.4060
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol			1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol	Not in list	C9H10ClN5O3	OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol			1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol	Not in list	C9H10ClN5O3	OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol			1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol	Not in list	C9H10ClN5O3	OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol			1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol	Not in list	C9H10ClN5O3	OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol			1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol	Not in list	C9H10ClN5O3	OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol			1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol	Not in list	C9H10ClN5O3	OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol			1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol	Not in list	C9H10ClN5O3	OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol			1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol	Not in list	C9H10ClN5O3	OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol			1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol	Not in list	C9H10ClN5O3	OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol			1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-5-ol dihydro-2-(nitroamino)-1H-imidazol-5-ol	Not in list	C9H10ClN5O3	OC2C\N=C(\N[N+]([O-])=O)N2Cc1cnc(Cl)cc1	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)5-14-8(16)4-12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol			1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol	Not in list	C18H20Cl2N10O6	OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol			1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol	Not in list	C18H20Cl2N10O6	OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol			1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol	Not in list	C18H20Cl2N10O6	OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol			1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol	Not in list	C18H20Cl2N10O6	OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol			1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol	Not in list	C18H20Cl2N10O6	OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol			1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol	Not in list	C18H20Cl2N10O6	OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol			1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol	Not in list	C18H20Cl2N10O6	OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol			1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol	Not in list	C18H20Cl2N10O6	OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol			1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol	Not in list	C18H20Cl2N10O6	OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol			1[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-2-(nitroamino)-1H-imidazol-4-ol dihydro-2-(nitroamino)-1H-imidazol-4-ol	Not in list	C18H20Cl2N10O6	OC/2CN(Cc1cnc(Cl)cc1)C(\N[N+]([O-])=O)=N\2	InChI=1/C9H10ClN5O3/c10-7-2-1-6(3-11-7)4-14-5-8(16)12-9(14)13-15(17)18/h1-3,8,16H,4-5H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine			1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine	Not in list	C9H8ClN5O2	O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1	InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine			1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine	Not in list	C9H8ClN5O2	O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1	InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine			1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine	Not in list	C9H8ClN5O2	O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1	InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine			1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine	Not in list	C9H8ClN5O2	O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1	InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine			1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine	Not in list	C9H8ClN5O2	O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1	InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine			1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine	Not in list	C9H8ClN5O2	O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1	InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine			1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine	Not in list	C9H8ClN5O2	O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1	InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine			1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine	Not in list	C9H8ClN5O2	O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1	InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine			1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine	Not in list	C9H8ClN5O2	O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1	InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine			1-[(6-Chloro-3-pyridinyl)methyl]N-nitro-1H-imidazol-2-amine	Not in list	C9H8ClN5O2	O=[N+]([O-])Nc2nccn2Cc1ccc(Cl)nc1	InChI=1/C9H8ClN5O2/c10-8-2-1-7(5-12-8)6-14-4-3-11-9(14)13-15(16)17/h1-5H,6H2,(H,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	BDF1 mouse		Male	oral: gavage			no data	not applicable	Inconclusive		no evidence	RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	oral: unspecified	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	oral: unspecified	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	BDF1 mouse		Male	intraperitoneal			no data	not applicable	Inconclusive		no evidence	RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	intraperitoneal	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	intraperitoneal	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Imidacloprid		138261-41-3	single chemical entity	Component is a metabolite of the substance	1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone			1-[(6-chloro-3-pyridinyl)methyl]-,oxohydrazone	Not in list	C9H10ClN5O	Clc2ncc(CN1CCN/C1=N\N=O)cc2	InChI=1/C9H10ClN5O/c10-8-2-1-7(5-12-8)6-15-4-3-11-9(15)13-14-16/h1-2,5H,3-4,6H2,(H,11,13,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Imidacloprid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance imidacloprid	28Jul2008	2008	doi:10.2903/j.efsa.2008.148r
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	N-{3-[(2RS)-2-hydroxybutan-2-yl]-1,2-oxazol-5-yl} -2,6-dimethoxybenzamide			N-(3-ethylisoxazol-5-yl)-2,6-dimethoxybenzamide	Not in list	C15H20N2O5	CCc2cc(NC(=O)c1c(OC)cccc1OC)on2	InChI=1/C14H16N2O4/c1-4-9-8-12(20-16-9)15-14(17)13-10(18-2)6-5-7-11(13)19-3/h5-8H,4H2,1-3H3,(H,15,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: Sweden	Isoxaben	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is a metabolite of the substance	2,6-dimethoxybenzamide			2,6-dimethoxybenzamide	Not in list	C9H11NO3	COc1cccc(OC)c1C(N)=O	InChI=1/C9H11NO3/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3,(H2,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Isoxaben	407-190-8	82558-50-7	single chemical entity	Component is identical to the substance	Isoxaben	407-190-8	82558-50-7	2,6-Dimethoxy-N-[3-(3-methylpentan-3-yl)-1,2-oxazol-5-yl]benzamide	Isoxaben	C18H24N2O4	CCC(C)(CC)C1=NOC(=C1)NC(=O)C2=C(C=CC=C2OC)OC	InChI=1S/C18H24N2O4/c1-6-18(3,7-2)14-11-15(24-20-14)19-17(21)16-12(22-4)9-8-10-13(16)23-5/h8-11H,6-7H2,1-5H3,(H,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Isoxaben (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoxaben	03Sep2010	2010	doi:10.2903/j.efsa.2010.1714
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	7	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	7	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA94			Not reported			no data	without	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA94			Not reported			no data	with	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA92			Not reported			no data	without	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA92			Not reported			no data	with	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Positive			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	DIS13			Not reported			no data	without	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)				Not reported			yes	with	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)				Not reported			yes	without	Positive			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	PQ37			Not reported			no data	without	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	5	Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	5	Female	other	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	5	Female	oral: gavage	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	5	Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	5	Female	other	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	5	Female	other	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ddy mouse	6	Male	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			no data	without	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Iron sulfate anhydrous	231-753-5	7720-78-7	single chemical entity	Component is identical to the substance	Iron sulfate anhydrous	231-753-5	7720-78-7	Iron(2+);sulfate	Not in list	FeO4S	[O-]S(=O)(=O)[O-].[Fe+2]	InChI=1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)/q+2;/p-2	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	kidney cells			Not reported			no data	without	Negative			RMS: The United Kingdom	Iron sulphate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance iron sulfate	25Jan2012	2012	doi:10.2903/j.efsa.2012.2521
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid			(2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid	Not in list	C17H17NO4	O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C	InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid			(2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid	Not in list	C17H17NO4	O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C	InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid			(2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid	Not in list	C17H17NO4	O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C	InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid			(2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid	Not in list	C17H17NO4	O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C	InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid			(2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid	Not in list	C17H17NO4	O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C	InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid			(2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid	Not in list	C17H17NO4	O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C	InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid			(2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid	Not in list	C17H17NO4	O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C	InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid			(2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid	Not in list	C17H17NO4	O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C	InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid			(2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid	Not in list	C17H17NO4	O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C	InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Kresoxim-methyl		143390-89-0	single chemical entity	Component is a metabolite of the substance	(E)-methoxyamino(α-(o-tolyloxy)-o-tolyl]acetic acid			(2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}ethanoic acid	Not in list	C17H17NO4	O=C(O)\C(=N\OC)c2ccccc2COc1ccccc1C	InChI=1/C17H17NO4/c1-12-7-3-6-10-15(12)22-11-13-8-4-5-9-14(13)16(17(19)20)18-21-2/h3-10H,11H2,1-2H3,(H,19,20)/b18-16+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Lithuania	Kresoxim-methyl	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance kresoxim-methyl	19Nov2010	2010	doi:10.2903/j.efsa.2010.1891
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	small colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	large colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	large colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	small colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar	5	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is identical to the substance	Isopyrazam		881685-58-1	3-(difluoromethyl)-1-methyl-N-[9-(propan-2-yl)-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]-1H-pyrazole-4-carboxamide	Isopyrazam	C20H23F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3cccc2C1CCC(C1C(C)C)c23	InChI=1S/C20H23F2N3O/c1-10(2)16-12-7-8-13(16)17-11(12)5-4-6-15(17)23-20(26)14-9-25(3)24-18(14)19(21)22/h4-6,9-10,12-13,16,19H,7-8H2,1-3H3,(H,23,26)	organic	representative compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	small colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	large colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	large colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	small colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	small colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	small colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	large colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	large colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	large colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1S,4R,9S)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-N-[(1R,8S,11S)-11-(2-hydroxypropan-2-yl)tricyclo[6.2.1.02,7]undeca-2,4,6-trien-3-yl]-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@H]1CC[C@H]([C@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	small colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Isopyrazam		881685-58-1	single chemical entity	Component is a metabolite of the substance	3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide			3-(difluoromethyl)-1-methyl-N-[(1R,4S,9R)-1,2,3,4-tetrahydro-9-(2-hydroxypropan-2-yl)-1,4-methanonaphthalen-5-yl]pyrazole-4-carboxamide	Not in list	C20H23F2N3O2	FC(F)c4nn(C)cc4C(=O)Nc3cccc2[C@@H]1CC[C@@H]([C@@H]1C(C)(C)O)c23	InChI=1/C20H23F2N3O2/c1-20(2,27)16-11-7-8-12(16)15-10(11)5-4-6-14(15)23-19(26)13-9-25(3)24-17(13)18(21)22/h4-6,9,11-12,16,18,27H,7-8H2,1-3H3,(H,23,26)/t11-,12+,16+/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	small colonies		RMS: The United Kingdom	Isopyrazam	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isopyrazam	29Mar2012	2012	doi:10.2903/j.efsa.2012.2600
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	large colonies		RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	small colonies		RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	small colonies		RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	large colonies		RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Not reported	3	Male	oral: unspecified	4.0000000000	h	yes	not applicable	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Not reported	3	Male	oral: unspecified	16.0000000000	h	yes	not applicable	Negative			RMS: Finland	Malathion	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Not reported	3	Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Not reported	3	Male	oral: unspecified	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	diethyl (2RS)-2-{[methoxy(methylsulfanyl)phosphoryl]sulfanyl}butanedioate			diethyl 2-[methoxy(methylsulfanyl)phosphoryl]sulfanylbutanedioate	Not in list	C10H19O6PS2	CCOC(=O)CC(C(=O)OCC)SP(=O)(OC)SC	InChI=1S/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(13,14-3)18-4/h8H,5-7H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-[(dimethoxyphosphoryl)sulfanyl]butanedioate		1634-78-2	Diethyl 2-dimethoxyphosphorylsulfanylbutanedioate	Malaoxon	C10H19O7PS	CCOC(=O)CC(C(=O)OCC)SP(=O)(OC)OC	InChI=1S/C10H19O7PS/c1-5-16-9(11)7-8(10(12)17-6-2)19-18(13,14-3)15-4/h8H,5-7H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	12.0000000000	week	yes, concurrent no treatment	not applicable	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	6.0000000000	week	yes, concurrent no treatment	not applicable	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	12.0000000000	week	yes, concurrent no treatment	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	12.0000000000	week	yes, concurrent no treatment	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	6.0000000000	week	yes, concurrent no treatment	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	12.0000000000	week	yes, concurrent no treatment	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	6.0000000000	week	yes, concurrent no treatment	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	12.0000000000	week	yes, concurrent no treatment	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	6.0000000000	week	yes, concurrent no treatment	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	12.0000000000	week	yes, concurrent no treatment	not applicable	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	12.0000000000	week	yes, concurrent no treatment	not applicable	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	6.0000000000	week	yes, concurrent no treatment	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	12.0000000000	week	yes, concurrent no treatment	not applicable	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	6.0000000000	week	yes, concurrent no treatment	not applicable	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	6.0000000000	week	yes, concurrent no treatment	not applicable	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: feed	6.0000000000	week	yes, concurrent no treatment	not applicable	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
Indolylbutyric acid	205-101-5	133-32-4	single chemical entity	Component is identical to the substance	Indolylbutyric acid	205-101-5	133-32-4	4-(1H-indol-3-yl)butanoic acid	Not in list	C12H13NO2	OC(=O)CCCc1c[nH]c2ccccc12	InChI=1/C12H13NO2/c14-12(15)7-3-4-9-8-13-11-6-2-1-5-10(9)11/h1-2,5-6,8,13H,3-4,7H2,(H,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Indolylbutiric acid (Revised DAR of September 2007)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance indolylbutyric acid	14Sep2010	2010	doi:10.2903/j.efsa.2010.1720
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP67			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM871			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM871			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP67			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	single chemical entity	Component is identical to the substance	2,4,6,8-Tetramethyl-1,3,5,7-tetraoxacyclooctane	203-600-2	108-62-3	2,4,6,8-Tetramethyl-1,3,5,7-tetroxocane	Metaldehyde	C8H16O4	CC1OC(C)OC(C)OC(C)O1	InChI=1/C8H16O4/c1-5-9-6(2)11-8(4)12-7(3)10-5/h5-8H,1-4H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Metaldehyde	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaldehyde	22Oct2010	2010	doi:10.2903/j.efsa.2010.1856
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is identical to the substance	Metobromuron	221-301-5	3060-89-7	3-(4-bromophenyl)-1-methoxy-1-methylurea	Metobromuron	C9H11BrN2O2	CN(C(=O)NC1=CC=C(C=C1)Br)OC	InChI=1S/C9H11BrN2O2/c1-12(14-2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Picolinafen	604-030-0	137641-05-5	single chemical entity	Component is identical to the substance	Picolinafen	604-030-0	137641-05-5	N-(4-fluorophenyl)-6-[3(trifluoromethyl)phenoxy]pyridine-2carboxamide	Picolinafen	C19H12F4N2O2	C1=CC(=CC(=C1)OC2=CC=CC(=N2)C(=O)NC3=CC=C(C=C3)F)C(F)(F)F	InChI=1S/C19H12F4N2O2/c20-13-7-9-14(10-8-13)24-18(26)16-5-2-6-17(25-16)27-15-4-1-3-12(11-15)19(21,22)23/h1-11H,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany - CoRMS: Latvia	Picolinafen	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picolinafen	04Nov2015	2015	doi:10.2903/j.efsa.2015.4279
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent no treatment	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent no treatment	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Picloram	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Picloram (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Picloram (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Picloram (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Picloram (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Picloram (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Picloram (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Picloram (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Picloram (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Picloram (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Picloram	217-636-1	1918-02-1	single chemical entity	Component is identical to the substance	Picloram	217-636-1	1918-02-1	4-amino-3,5,6-trichloropyridine-2-carboxylic acid	Picloram	C6H3Cl3N2O2	C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N	InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Picloram (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance picloram	03Dec2009	2009	doi:10.2903/j.efsa.2009.1390
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	40	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	40	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Pyriproxyfen		95737-68-1	single chemical entity	Component is identical to the substance	Pyriproxyfen		95737-68-1	2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine	Pyriproxyfen	C20H19NO3	CC(OC3=NC=CC=C3)COC2=CC=C(C=C2)OC1=CC=CC=C1	InChI=1S/C20H19NO3/c1-16(23-20-9-5-6-14-21-20)15-22-17-10-12-19(13-11-17)24-18-7-3-2-4-8-18/h2-14,16H,15H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	40	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Pyriproxyfen	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance pyriproxyfen	06Aug2009	2009	doi:10.2903/j.efsa.2009.336r
Propargite	219-006-1	2312-35-8	single chemical entity	Component is identical to the substance	Propargite	219-006-1	2312-35-8	2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite	Propargite	C19H26O4S	CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C	InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Propargite	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance propargite	11May2011	2011	doi:10.2903/j.efsa.2011.2087
Propargite	219-006-1	2312-35-8	single chemical entity	Component is identical to the substance	Propargite	219-006-1	2312-35-8	2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite	Propargite	C19H26O4S	CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C	InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Propargite	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance propargite	11May2011	2011	doi:10.2903/j.efsa.2011.2087
Propargite	219-006-1	2312-35-8	single chemical entity	Component is identical to the substance	Propargite	219-006-1	2312-35-8	2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite	Propargite	C19H26O4S	CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C	InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Propargite	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance propargite	11May2011	2011	doi:10.2903/j.efsa.2011.2087
Propargite	219-006-1	2312-35-8	single chemical entity	Component is identical to the substance	Propargite	219-006-1	2312-35-8	2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite	Propargite	C19H26O4S	CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C	InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Propargite	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance propargite	11May2011	2011	doi:10.2903/j.efsa.2011.2087
Propargite	219-006-1	2312-35-8	single chemical entity	Component is identical to the substance	Propargite	219-006-1	2312-35-8	2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite	Propargite	C19H26O4S	CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C	InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Propargite	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance propargite	11May2011	2011	doi:10.2903/j.efsa.2011.2087
Propargite	219-006-1	2312-35-8	single chemical entity	Component is identical to the substance	Propargite	219-006-1	2312-35-8	2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite	Propargite	C19H26O4S	CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C	InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Propargite	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance propargite	11May2011	2011	doi:10.2903/j.efsa.2011.2087
Propargite	219-006-1	2312-35-8	single chemical entity	Component is identical to the substance	Propargite	219-006-1	2312-35-8	2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite	Propargite	C19H26O4S	CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C	InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Propargite	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance propargite	11May2011	2011	doi:10.2903/j.efsa.2011.2087
Propargite	219-006-1	2312-35-8	single chemical entity	Component is identical to the substance	Propargite	219-006-1	2312-35-8	2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite	Propargite	C19H26O4S	CC(C)(C)c1ccc(cc1)OC2CCCCC2OS(=O)OCC#C	InChI=1S/C19H26O4S/c1-5-14-21-24(20)23-18-9-7-6-8-17(18)22-16-12-10-15(11-13-16)19(2,3)4/h1,10-13,17-18H,6-9,14H2,2-4H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Propargite	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance propargite	11May2011	2011	doi:10.2903/j.efsa.2011.2087
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Prosulfocarb	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden	Prosulfocarb (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Prosulfocarb	401-730-6	52888-80-9	single chemical entity	Component is identical to the substance	Prosulfocarb	401-730-6	52888-80-9	S-benzyl dipropylcarbamothioate	Prosulfocarb	C14H21NOS	CCCN(CCC)C(=O)SCc1ccccc1	InChI=1S/C14H21NOS/c1-3-10-15(11-4-2)14(16)17-12-13-8-6-5-7-9-13/h5-9H,3-4,10-12H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Sweden	Prosulfocarb (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prosulfocarb	28Aug2007	2007	doi:10.2903/j.efsa.2007.111r
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	3	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is identical to the substance	Pyriofenone		688046-61-9	(5-Chloro-2-methoxy-4-methylpyridin-3-yl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Not in list	C18H20ClNO5	CC1=CC(=C(C(=C1C(=O)C2=C(C(=CN=C2OC)Cl)C)OC)OC)OC	InChI=1S/C18H20ClNO5/c1-9-7-12(22-3)16(23-4)17(24-5)13(9)15(21)14-10(2)11(19)8-20-18(14)25-6/h7-8H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	3	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is a metabolite of the substance	(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone			(5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone	Not in list	C17H18ClNO5	COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc	InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is a metabolite of the substance	(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone			(5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone	Not in list	C17H18ClNO5	COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc	InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is a metabolite of the substance	(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone			(5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone	Not in list	C17H18ClNO5	COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc	InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is a metabolite of the substance	(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone			(5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone	Not in list	C17H18ClNO5	COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc	InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is a metabolite of the substance	(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone			(5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone	Not in list	C17H18ClNO5	COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc	InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is a metabolite of the substance	(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone			(5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone	Not in list	C17H18ClNO5	COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc	InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is a metabolite of the substance	(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone			(5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone	Not in list	C17H18ClNO5	COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc	InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is a metabolite of the substance	(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone			(5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone	Not in list	C17H18ClNO5	COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc	InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is a metabolite of the substance	(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone			(5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone	Not in list	C17H18ClNO5	COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc	InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyriofenone		688046-61-9	single chemical entity	Component is a metabolite of the substance	(5-chloro-2-methoxy-4-methyl-3-pyridinyl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone			(5-chloro-2-methoxy-4-methylpyridin-3-yl)(4-hydroxy-2,3-dimethoxy-6-methylphenyl)methanone	Not in list	C17H18ClNO5	COc2ncc(Cl)c(C)c2C(=O)c1c(C)cc(O)c(OC)C1oc	InChI=1/C17H18ClNO5/c1-8-6-11(20)15(22-3)16(23-4)12(8)14(21)13-9(2)10(18)7-19-17(13)24-5/h6-7,20H,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyriofenone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyriofenone.	03Apr2013	2013	doi:10.2903/j.efsa.2013.3147
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP67			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP67			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM871			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM871			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	12	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is identical to the substance	Pyridaben	405-700-3	96489-71-3	2-tert-butyl-5-[(4-tert-butylbenzyl)thio]-4-chloropyridazin-3(2H)-one	Pyridaben	C19H25ClN2OS	O=C1N(C(C)(C)C)N=CC(SCC2=CC=C(C(C)(C)C)C=C2)=C1Cl	InChI=1S/C19H25ClN2OS/c1-18(2,3)14-9-7-13(8-10-14)12-24-15-11-21-22(19(4,5)6)17(23)16(15)20/h7-11H,12H2,1-6H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	12	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP67			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM871			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	CM871			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Pyridaben	405-700-3	96489-71-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid			2-(4-{[(1-tert-butyl-5-chloro-6-oxo-1,6-dihydropyridazin-4-yl)sulfanyl]methyl}phenyl)-2-methylpropanoic acid	Not in list	C19H23ClN2O3S	CC(C)(C)N2N=CC(SCc1ccc(cc1)C(C)(C)C(=O)O)=C(Cl)C2=O	InChI=1/C19H23ClN2O3S/c1-18(2,3)22-16(23)15(20)14(10-21-22)26-11-12-6-8-13(9-7-12)19(4,5)17(24)25/h6-10H,11H2,1-5H3,(H,24,25)	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP67			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyridaben	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridaben	08Jun2010	2010	doi:10.2903/j.efsa.2010.1632
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Meptyldinocap	228-088-8	131-72-6	single chemical entity	Component is identical to the substance	Meptyldinocap	228-088-8	131-72-6	(2,4-dinitro-6-octan-2-ylphenyl) (E)-but-2-enoate	Meptyldinocap (sum of 2,4 DNOPC and 2,4 DNOP expressed as meptyldinocap)	C18H24N2O6	CCCCCCC(C)C1=CC(=CC(=C1OC(=O)C=CC)[N+](=O)[O-])[N+](=O)[O-]	InChI=1S/C18H24N2O6/c1-4-6-7-8-10-13(3)15-11-14(19(22)23)12-16(20(24)25)18(15)26-17(21)9-5-2/h5,9,11-13H,4,6-8,10H2,1-3H3/b9-5+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Meptyldinocap (DE-126)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance DE-126, referred to as meptyldinocap in Commission Decision 2006/589/EC	03Jan2014	2014	doi:10.2903/j.efsa.2014.3473
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is identical to the substance	Mepiquat chloride	246-147-6	24307-26-4	1,1-Dimethylpiperidin-1-ium;chloride	Not in list	C7H16ClN	C[N+]1(CCCCC1)C.[Cl-]	InChI=1S/C7H16N.ClH/c1-8(2)6-4-3-5-7-8;/h3-7H2,1-2H3;1H/q+1;/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	NMRI	20	Male	oral: feed	5.0000000000	D	yes	not applicable	Negative			RMS: The United Kingdom	Mepiquat-chloride	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,1-dimethylpiperidinium chloride			4-hydroxy-1,1-dimethylpiperidinium chloride	Not in list	C7H16ClNO	[Cl-].C[N+]1(C)CCC(O)CC1	InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride (Addendum 2)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,1-dimethylpiperidinium chloride			4-hydroxy-1,1-dimethylpiperidinium chloride	Not in list	C7H16ClNO	[Cl-].C[N+]1(C)CCC(O)CC1	InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride (Addendum 2)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,1-dimethylpiperidinium chloride			4-hydroxy-1,1-dimethylpiperidinium chloride	Not in list	C7H16ClNO	[Cl-].C[N+]1(C)CCC(O)CC1	InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride (Addendum 2)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,1-dimethylpiperidinium chloride			4-hydroxy-1,1-dimethylpiperidinium chloride	Not in list	C7H16ClNO	[Cl-].C[N+]1(C)CCC(O)CC1	InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride (Addendum 2)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,1-dimethylpiperidinium chloride			4-hydroxy-1,1-dimethylpiperidinium chloride	Not in list	C7H16ClNO	[Cl-].C[N+]1(C)CCC(O)CC1	InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride (Addendum 2)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,1-dimethylpiperidinium chloride			4-hydroxy-1,1-dimethylpiperidinium chloride	Not in list	C7H16ClNO	[Cl-].C[N+]1(C)CCC(O)CC1	InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride (Addendum 2)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,1-dimethylpiperidinium chloride			4-hydroxy-1,1-dimethylpiperidinium chloride	Not in list	C7H16ClNO	[Cl-].C[N+]1(C)CCC(O)CC1	InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride (Addendum 2)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,1-dimethylpiperidinium chloride			4-hydroxy-1,1-dimethylpiperidinium chloride	Not in list	C7H16ClNO	[Cl-].C[N+]1(C)CCC(O)CC1	InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride (Addendum 2)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,1-dimethylpiperidinium chloride			4-hydroxy-1,1-dimethylpiperidinium chloride	Not in list	C7H16ClNO	[Cl-].C[N+]1(C)CCC(O)CC1	InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Mepiquat-chloride (Addendum 2)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Mepiquat chloride	246-147-6	24307-26-4	single chemical entity	Component is a metabolite of the substance	4-hydroxy-1,1-dimethylpiperidinium chloride			4-hydroxy-1,1-dimethylpiperidinium chloride	Not in list	C7H16ClNO	[Cl-].C[N+]1(C)CCC(O)CC1	InChI=1/C7H16NO.ClH/c1-8(2)5-3-7(9)4-6-8;/h7,9H,3-6H2,1-2H3;1H/q+1;/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Mepiquat-chloride (Addendum 2)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance mepiquat	28Jul2008	2008	doi:10.2903/j.efsa.2008.146r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	20	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is identical to the substance	Oxamyl		23135-22-0	(EZ)-N,N-dimethyl-2-methylcarbamoyloxyimino-2-(methylthio)acetamide	Oxamyl	C7H13N3O3S	CNC(=O)O/N=C(/C(=O)N(C)C)\SC	InChI=1S/C7H13N3O3S/c1-8-7(12)13-9-5(14-4)6(11)10(2)3/h1-4H3,(H,8,12)/b9-5-	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	20	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-1-cyanoformamide			[(cyanocarbonyl)azanediyl]dimethane	Not in list	C4H6N2O	CN(C)C(=O)C#N	InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-1-cyanoformamide			[(cyanocarbonyl)azanediyl]dimethane	Not in list	C4H6N2O	CN(C)C(=O)C#N	InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-1-cyanoformamide			[(cyanocarbonyl)azanediyl]dimethane	Not in list	C4H6N2O	CN(C)C(=O)C#N	InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-1-cyanoformamide			[(cyanocarbonyl)azanediyl]dimethane	Not in list	C4H6N2O	CN(C)C(=O)C#N	InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-1-cyanoformamide			[(cyanocarbonyl)azanediyl]dimethane	Not in list	C4H6N2O	CN(C)C(=O)C#N	InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-1-cyanoformamide			[(cyanocarbonyl)azanediyl]dimethane	Not in list	C4H6N2O	CN(C)C(=O)C#N	InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-1-cyanoformamide			[(cyanocarbonyl)azanediyl]dimethane	Not in list	C4H6N2O	CN(C)C(=O)C#N	InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-1-cyanoformamide			[(cyanocarbonyl)azanediyl]dimethane	Not in list	C4H6N2O	CN(C)C(=O)C#N	InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-1-cyanoformamide			[(cyanocarbonyl)azanediyl]dimethane	Not in list	C4H6N2O	CN(C)C(=O)C#N	InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Oxamyl		23135-22-0	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-1-cyanoformamide			[(cyanocarbonyl)azanediyl]dimethane	Not in list	C4H6N2O	CN(C)C(=O)C#N	InChI=1S/C4H6N2O/c1-6(2)4(7)3-5/h1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Oxamyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxamyl	31Mar2005	2005	doi:10.2903/j.efsa.2005.26r
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: unspecified	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Pyraflufen-ethyl	603-347-1	129630-19-9	single chemical entity	Component is identical to the substance	Pyraflufen-ethyl	603-347-1	129630-19-9	ethyl 2-[2-chloro-5-[4-chloro-5-(difluoromethoxy)-1-methylpyrazol-3-yl]-4-fluorophenoxy]acetate	Pyraflufen-ethyl	C15H13Cl2F3N2O4	CCOC(=O)COC1=C(C=C(C(=C1)C2=NN(C(=C2Cl)OC(F)F)C)F)Cl	InChI=1S/C15H13Cl2F3N2O4/c1-3-24-11(23)6-25-10-4-7(9(18)5-8(10)16)13-12(17)14(22(2)21-13)26-15(19)20/h4-5,15H,3,6H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Pyraflufen-ethyl (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyraflufen-ethyl	05Feb2015	2015	doi:10.2903/j.efsa.2015.4001
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Methomyl	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methomyl (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Methomyl	240-815-0	16752-77-5	single chemical entity	Component is identical to the substance	Methomyl	240-815-0	16752-77-5	methyl N-[(methylcarbamoyl)oxy]ethanimidothioate	Methomyl	C5H10N2O2S	CSC(C)=NOC(NC)=O	InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8)/b7-4-	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methomyl (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance methomyl	06Apr2009	2009	doi:10.2903/j.efsa.2009.222r
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Metrafenone		220899-03-6	single chemical entity	Component is identical to the substance	Metrafenone		220899-03-6	(3-Bromo-6-methoxy-2-methylphenyl)-(2,3,4-trimethoxy-6-methylphenyl)methanone	Metrafenone	C19H21BrO5	CC1=CC(=C(C(=C1C(=O)C2=C(C=CC(=C2C)Br)OC)OC)OC)OC	InChI=1S/C19H21BrO5/c1-10-9-14(23-4)18(24-5)19(25-6)15(10)17(21)16-11(2)12(20)7-8-13(16)22-3/h7-9H,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Metrafenone	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metrafenone	01Feb2006	2006	doi:10.2903/j.efsa.2006.58r
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	without	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	without	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	with	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	with	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: gavage	24.0000000000	h	no data	not applicable	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: gavage	6.0000000000	h	no data	not applicable	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: gavage	48.0000000000	h	no data	not applicable	Negative			RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Prohexadione-calcium		127277-53-6	single chemical entity	Component is identical to the substance	Prohexadione-calcium		127277-53-6	Calcium;1-(4-carboxy-2,6-dioxocyclohexylidene)propan-1-olate	Not in list	C20H22CaO10	CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].CCC(=C1C(=O)CC(CC1=O)C(=O)O)[O-].[Ca+2]	InChI=1S/2C10H12O5.Ca/c2*1-2-6(11)9-7(12)3-5(10(14)15)4-8(9)13;/h2*5,11H,2-4H2,1H3,(H,14,15);/q;;+2/p-2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: France	Prohexadione-calcium	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prohexadione (considered variant prohexadione-calcium)	26Mar2010	2010	doi:10.2903/j.efsa.2010.1555
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Inconclusive			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Inconclusive			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is identical to the substance	Proquinazid		189278-12-4	6-iodo-2-propoxy-3-propylquinazolin-4(3H)-one	Proquinazid	C14H17IN2O2	Ic1ccc2N=C(OCCC)N(CCC)C(=O)c2c1	InChI=1S/C14H17IN2O2/c1-3-7-17-13(18)11-9-10(15)5-6-12(11)16-14(17)19-8-4-2/h5-6,9H,3-4,7-8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	with	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Proquinazid		189278-12-4	single chemical entity	Component is a metabolite of the substance	2-Propoxy-3-propylquinazolin-4(3H)-one			2-propoxy-3-propylquinazolin-4(3H)-one	Not in list	C14H18N2O2	CCCOC2=Nc1ccccc1C(=O)N2CCC	InChI=1S/C14H18N2O2/c1-3-9-16-13(17)11-7-5-6-8-12(11)15-14(16)18-10-4-2/h5-8H,3-4,9-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity$indirect-toxicokinetic investigations	RMS: The United Kingdom	Proquinazid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance proquinazid	29Oct2009	2009	doi:10.2903/j.efsa.2009.1350
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	CM881			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	CM881			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	6	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is identical to the substance	Pyrimethanil	414-220-3	53112-28-0	4,6-dimethyl-N-phenylpyrimidin-2-amine	Pyrimethanil	C12H13N3	CC1=NC(NC2=CC=CC=C2)=NC(C)=C1	InChI=1S/C12H13N3/c1-9-8-10(2)14-12(13-9)15-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,13,14,15)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	6	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dimethylpyrimidine			4,6-dimethylpyrimidin-2-amine	Pyrimethanil metabolite (AEF132593)	C6H9N3	Cc1cc(C)nc(N)n1	InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dimethylpyrimidine			4,6-dimethylpyrimidin-2-amine	Pyrimethanil metabolite (AEF132593)	C6H9N3	Cc1cc(C)nc(N)n1	InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dimethylpyrimidine			4,6-dimethylpyrimidin-2-amine	Pyrimethanil metabolite (AEF132593)	C6H9N3	Cc1cc(C)nc(N)n1	InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dimethylpyrimidine			4,6-dimethylpyrimidin-2-amine	Pyrimethanil metabolite (AEF132593)	C6H9N3	Cc1cc(C)nc(N)n1	InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dimethylpyrimidine			4,6-dimethylpyrimidin-2-amine	Pyrimethanil metabolite (AEF132593)	C6H9N3	Cc1cc(C)nc(N)n1	InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dimethylpyrimidine			4,6-dimethylpyrimidin-2-amine	Pyrimethanil metabolite (AEF132593)	C6H9N3	Cc1cc(C)nc(N)n1	InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dimethylpyrimidine			4,6-dimethylpyrimidin-2-amine	Pyrimethanil metabolite (AEF132593)	C6H9N3	Cc1cc(C)nc(N)n1	InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dimethylpyrimidine			4,6-dimethylpyrimidin-2-amine	Pyrimethanil metabolite (AEF132593)	C6H9N3	Cc1cc(C)nc(N)n1	InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dimethylpyrimidine			4,6-dimethylpyrimidin-2-amine	Pyrimethanil metabolite (AEF132593)	C6H9N3	Cc1cc(C)nc(N)n1	InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Pyrimethanil	414-220-3	53112-28-0	single chemical entity	Component is a metabolite of the substance	2-amino-4,6-dimethylpyrimidine			4,6-dimethylpyrimidin-2-amine	Pyrimethanil metabolite (AEF132593)	C6H9N3	Cc1cc(C)nc(N)n1	InChI=1/C6H9N3/c1-4-3-5(2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Pyrimethanil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pyrimethanil	21Feb2006	2006	doi:10.2903/j.efsa.2006.61r
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	8	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Sprague-Dawley	2	Male	oral: gavage	24.0000000000	h	no data	not applicable	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Oxadiazon	243-215-7	19666-30-9	single chemical entity	Component is identical to the substance	Oxadiazon	243-215-7	19666-30-9	5-Tert-butyl-3-(2,4-dichloro-5-propan-2-yloxyphenyl)-1,3,4-oxadiazol-2-one	Oxadiazon	C15H18Cl2N2O3	CC(C)OC1=C(C=C(C(=C1)N2C(=O)OC(=N2)C(C)(C)C)Cl)Cl	InChI=1S/C15H18Cl2N2O3/c1-8(2)21-12-7-11(9(16)6-10(12)17)19-14(20)22-13(18-19)15(3,4)5/h6-8H,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	CD-1	4	Male	oral: gavage	24.0000000000	h	no data	not applicable	Negative			RMS: Italy	Oxadiazon	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxadiazon	19Feb2010	2010	doi:10.2903/j.efsa.2010.1389
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-proficient			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-proficient			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	6.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Methiocarb	217-991-2	2032-65-7	single chemical entity	Component is identical to the substance	Methiocarb	217-991-2	2032-65-7	3,5-dimethyl-4-(methylsulfanyl)phenyl methylcarbamate	Methiocarb	C11H15NO2S	CNC(=O)Oc1cc(C)c(SC)c(C)c1	InChI=1/C11H15NO2S/c1-7-5-9(14-11(13)12-3)6-8(2)10(7)15-4/h5-6H,1-4H3,(H,12,13)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	NMRI	50	Male	oral: unspecified	48.0000000000	D	yes	not applicable	Negative			RMS: The United Kingdom	Methiocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance methiocarb	30Jul2012	2012	doi:10.2903/j.efsa.2012.2758
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Pyrethrins		8003-34-7	complex product: derived from botanical sources	Component is identical to the substance	Pyrethrins		8003-34-7	[(1S)-2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[2-methyl-4-oxo-3-[(2E)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1R)-3-[(E)-3-methoxy-2-methyl-3-oxoprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate	Pyrethrins	C43H56O8	CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C)CC=CC=C.CC1=C(C(=O)CC1OC(=O)C2C(C2(C)C)C=C(C)C(=O)OC)CC=CC=C	InChI=1S/C22H28O5.C21H28O3/c1-7-8-9-10-15-14(3)18(12-17(15)23)27-21(25)19-16(22(19,4)5)11-13(2)20(24)26-6;1-7-8-9-10-15-14(4)18(12-17(15)22)24-20(23)19-16(11-13(2)3)21(19,5)6/h7-9,11,16,18-19H,1,10,12H2,2-6H3;7-9,11,16,18-19H,1,10,12H2,2-6H3/b9-8+,13-11+;9-8+/t16?,18?,19-;16?,18-,19-/m00/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Pyrethrins (Final Addendum to the DAR)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyrethrins	09Jan2013	2013	doi:10.2903/j.efsa.2013.3032
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	25.5000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	25.5000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	50	Male	oral: gavage			yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is identical to the substance	Metamitron	255-349-3	41394-05-2	4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one	Metamitron	C10H10N4O	O=C1C(C2=CC=CC=C2)=NN=C(C)N1N	InChI=1S/C10H10N4O/c1-7-12-13-9(10(15)14(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Wistar	30	Male	oral: gavage	10.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is a metabolite of the substance	3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide			4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide	Not in list	C10H10N4O2	O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N	InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is a metabolite of the substance	3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide			4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide	Not in list	C10H10N4O2	O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N	InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is a metabolite of the substance	3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide			4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide	Not in list	C10H10N4O2	O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N	InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is a metabolite of the substance	3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide			4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide	Not in list	C10H10N4O2	O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N	InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is a metabolite of the substance	3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide			4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide	Not in list	C10H10N4O2	O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N	InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is a metabolite of the substance	3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide			4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide	Not in list	C10H10N4O2	O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N	InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is a metabolite of the substance	3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide			4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide	Not in list	C10H10N4O2	O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N	InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metamitron	255-349-3	41394-05-2	single chemical entity	Component is a metabolite of the substance	3-methyl-4-amino-6-phenyl-1,2,4-triazine-5-one-oxide			4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one 1-oxide	Not in list	C10H10N4O2	O=C2C(c1ccccc1)=[N+]([O-])N=C(C)N2N	InChI=1/C10H10N4O2/c1-7-12-14(16)9(10(15)13(7)11)8-5-3-2-4-6-8/h2-6H,11H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metamitron	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metamitron	22Oct2008	2008	doi:10.2903/j.efsa.2008.185r
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	20	Male	oral: unspecified	8.0000000000	week	yes, concurrent no treatment	not applicable	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar	10	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar	10	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is identical to the substance	Mandipropamid		374726-62-2	2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-yn-1-yloxy)acetamide	Mandipropamid	C23H22ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCc2ccc(OCC#C)c(OC)c2	InChI=1S/C23H22ClNO4/c1-4-14-28-20-11-6-17(16-21(20)27-3)12-13-25-23(26)22(29-15-5-2)18-7-9-19(24)10-8-18/h1-2,6-11,16,22H,12-15H2,3H3,(H,25,26)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Mandipropamid		374726-62-2	single chemical entity	Component is a metabolite of the substance	(4-Chloro-phenyl)-prop-2-ynyloxy-acetic acid			3-{[(4-chlorophenyl)(prop-2-yn-1-yloxy)acetyl]amino}propanoic acid	Not in list	C14H14ClNO4	Clc1ccc(cc1)C(OCC#C)C(=O)NCCC(=O)O	InChI=1/C14H14ClNO4/c1-2-9-20-13(10-3-5-11(15)6-4-10)14(19)16-8-7-12(17)18/h1,3-6,13H,7-9H2,(H,16,19)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Mandipropamid	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance mandipropamid	05Nov2012	2012	doi:10.2903/j.efsa.2012.2935
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	16	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	16	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	16	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is identical to the substance	Lufenuron		103055-07-8	N-{[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide	Lufenuron	C17H8Cl2F8N2O3	O=C(NC(NC2=C(Cl)C=C(OC(F)(F)C(F)C(F)(F)F)C(Cl)=C2)=O)C1=C(F)C=CC=C1F	InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is a metabolite of the substance	2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine			2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline	Not in list	C9H5Cl2F6NO	Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F	InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is a metabolite of the substance	2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine			2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline	Not in list	C9H5Cl2F6NO	Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F	InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is a metabolite of the substance	2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine			2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline	Not in list	C9H5Cl2F6NO	Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F	InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is a metabolite of the substance	2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine			2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline	Not in list	C9H5Cl2F6NO	Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F	InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is a metabolite of the substance	2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine			2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline	Not in list	C9H5Cl2F6NO	Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F	InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is a metabolite of the substance	2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine			2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline	Not in list	C9H5Cl2F6NO	Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F	InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is a metabolite of the substance	2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine			2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline	Not in list	C9H5Cl2F6NO	Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F	InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is a metabolite of the substance	2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine			2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline	Not in list	C9H5Cl2F6NO	Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F	InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is a metabolite of the substance	2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine			2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline	Not in list	C9H5Cl2F6NO	Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F	InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Lufenuron		103055-07-8	single chemical entity	Component is a metabolite of the substance	2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoro-propoxy)-phenylamine			2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)aniline	Not in list	C9H5Cl2F6NO	Clc1cc(N)c(Cl)cc1OC(F)(F)C(F)C(F)(F)F	InChI=1S/C9H5Cl2F6NO/c10-3-2-6(4(11)1-5(3)18)19-9(16,17)7(12)8(13,14)15/h1-2,7H,18H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Portugal	Lufenuron	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance lufenuron	22Jun2009	2009	doi:10.2903/j.efsa.2009.189r
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide			5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide	Not in list	C9H9Cl2N5O2S	O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2	InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide			5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide	Not in list	C9H9Cl2N5O2S	O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2	InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide			5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide	Not in list	C9H9Cl2N5O2S	O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2	InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide			5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide	Not in list	C9H9Cl2N5O2S	O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2	InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide			5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide	Not in list	C9H9Cl2N5O2S	O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2	InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide			5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide	Not in list	C9H9Cl2N5O2S	O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2	InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide			5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide	Not in list	C9H9Cl2N5O2S	O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2	InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide			5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide	Not in list	C9H9Cl2N5O2S	O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2	InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide			5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide	Not in list	C9H9Cl2N5O2S	O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2	InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	5-Amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide			5-amino-N-(2,6-dichloro-3-methylphenyl)-1H-1,2,4-triazole-3-sulfonamide	Not in list	C9H9Cl2N5O2S	O=S(=O)(Nc1c(Cl)c(C)ccc1Cl)c2nc(N)nn2	InChI=1S/C9H9Cl2N5O2S/c1-4-2-3-5(10)7(6(4)11)16-19(17,18)9-13-8(12)14-15-9/h2-3,16H,1H3,(H3,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C13H11Cl2N5O4S	Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC	InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C13H11Cl2N5O4S	Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC	InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C13H11Cl2N5O4S	Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC	InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C13H11Cl2N5O4S	Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC	InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C13H11Cl2N5O4S	Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC	InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C13H11Cl2N5O4S	Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC	InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C13H11Cl2N5O4S	Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC	InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C13H11Cl2N5O4S	Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC	InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C13H11Cl2N5O4S	Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC	InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4] triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C13H11Cl2N5O4S	Clc1c(C)ccc(Cl)c1NS(=O)(=O)c2nc3nc(cc(O)n3n2)OC	InChI=1S/C13H11Cl2N5O4S/c1-6-3-4-7(14)11(10(6)15)19-25(22,23)13-17-12-16-8(24-2)5-9(21)20(12)18-13/h3-5,19,21H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C12H9Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1	InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C12H9Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1	InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C12H9Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1	InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C12H9Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1	InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C12H9Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1	InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C12H9Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1	InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C12H9Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1	InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C12H9Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1	InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C12H9Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1	InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is a metabolite of the substance	N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide			N-(2,6-dichloro-3-methylphenyl)-5,7-dihydroxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Not in list	C12H9Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(O)cc(O)n2n1	InChI=1S/C12H9Cl2N5O4S/c1-5-2-3-6(13)10(9(5)14)18-24(22,23)12-16-11-15-7(20)4-8(21)19(11)17-12/h2-4,18,21H,1H3,(H,15,16,17,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	20.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metosulam		139528-85-1	single chemical entity	Component is identical to the substance	Metosulam		139528-85-1	N-(2,6-dichloro-3-methylphenyl)-5,7-dimethoxy[1,2,4]triazolo[1,5-a]pyrimidine-2-sulfonamide	Metosulam	C14H13Cl2N5O4S	Clc3c(C)ccc(Cl)c3NS(=O)(=O)c1nc2nc(cc(OC)n2n1)OC	InChI=1S/C14H13Cl2N5O4S/c1-7-4-5-8(15)12(11(7)16)20-26(22,23)14-18-13-17-9(24-2)6-10(25-3)21(13)19-14/h4-6,20H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Metosulam (Addendum)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metosulam	05May2010	2010	doi:10.2903/j.efsa.2010.1592
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: unspecified	14.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is identical to the substance	Metaflumizone	604-167-6	139968-49-3	1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Metaflumizone (sum of E- and Z- isomers)	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21+	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: unspecified	3.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is part of a group assessment	Z-isomer of metaflumizone	604-167-6	139968-49-3	1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Not in list	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21-	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is part of a group assessment	Z-isomer of metaflumizone	604-167-6	139968-49-3	1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Not in list	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21-	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is part of a group assessment	Z-isomer of metaflumizone	604-167-6	139968-49-3	1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Not in list	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21-	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is part of a group assessment	Z-isomer of metaflumizone	604-167-6	139968-49-3	1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Not in list	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21-	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is part of a group assessment	Z-isomer of metaflumizone	604-167-6	139968-49-3	1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Not in list	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21-	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is part of a group assessment	Z-isomer of metaflumizone	604-167-6	139968-49-3	1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Not in list	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21-	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is part of a group assessment	Z-isomer of metaflumizone	604-167-6	139968-49-3	1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Not in list	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21-	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is part of a group assessment	Z-isomer of metaflumizone	604-167-6	139968-49-3	1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Not in list	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21-	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is part of a group assessment	Z-isomer of metaflumizone	604-167-6	139968-49-3	1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Not in list	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21-	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is part of a group assessment	Z-isomer of metaflumizone	604-167-6	139968-49-3	1-[(Z)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea	Not in list	C24H16F6N4O2	C1=CC(=CC(=C1)C(F)(F)F)C(=NNC(=O)NC2=CC=C(C=C2)OC(F)(F)F)CC3=CC=C(C=C3)C#N	InChI=1S/C24H16F6N4O2/c25-23(26,27)18-3-1-2-17(13-18)21(12-15-4-6-16(14-31)7-5-15)33-34-22(35)32-19-8-10-20(11-9-19)36-24(28,29)30/h1-11,13H,12H2,(H2,32,34,35)/b33-21-	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Positive			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{(5RS)-5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile			4-{5-hydroxy-3-oxo-4-[4-(trifluoromethoxy)phenyl]-6-[3-(trifluoromethyl)phenyl]-2,3,4,5-tetrahydro-1,2,4-triazin-5-yl}benzonitrile	Not in list	C25H17F5N4O3	CC(F)(F)Oc1ccc(cc1)N3C(=O)NN=C(c2cc(ccc2)C(F)(F)F)C3(O)c4ccc(C#N)cc4	InChI=1/C25H17F5N4O3/c1-23(26,27)37-20-11-9-19(10-12-20)34-22(35)33-32-21(16-3-2-4-18(13-16)25(28,29)30)24(34,36)17-7-5-15(14-31)6-8-17/h2-13,36H,1H3,(H,33,35)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile			4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile	Not in list	C16H10F3NO	FC(F)(F)c1cccc(c1)C(=O)Cc2ccc(C#N)cc2	InChI=1/C16H10F3NO/c17-16(18,19)14-3-1-2-13(9-14)15(21)8-11-4-6-12(10-20)7-5-11/h1-7,9H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile			4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile	Not in list	C16H10F3NO	FC(F)(F)c1cccc(c1)C(=O)Cc2ccc(C#N)cc2	InChI=1/C16H10F3NO/c17-16(18,19)14-3-1-2-13(9-14)15(21)8-11-4-6-12(10-20)7-5-11/h1-7,9H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile			4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile	Not in list	C16H10F3NO	FC(F)(F)c1cccc(c1)C(=O)Cc2ccc(C#N)cc2	InChI=1/C16H10F3NO/c17-16(18,19)14-3-1-2-13(9-14)15(21)8-11-4-6-12(10-20)7-5-11/h1-7,9H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile			4-{2-oxo-2-[3-(trifluoromethyl)phenyl]ethyl}benzonitrile	Not in list	C16H10F3NO	FC(F)(F)c1cccc(c1)C(=O)Cc2ccc(C#N)cc2	InChI=1/C16H10F3NO/c17-16(18,19)14-3-1-2-13(9-14)15(21)8-11-4-6-12(10-20)7-5-11/h1-7,9H,8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Metaflumizone	604-167-6	139968-49-3	single chemical entity	Component is a metabolite of the substance	4-cyanobenzoic acid	210-606-9		4-cyanobenzoic acid	Not in list	C8H5NO2	C1=CC(=CC=C1C#N)C(=O)O	InChI=1S/C8H5NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h1-4H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Metaflumizone	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metaflumizone.	03Oct2013	2013	doi:10.2903/j.efsa.2013.3373
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	4.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	14.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide			N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide	C13H10ClF3N6O5S	FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2	InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide			N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide	C13H10ClF3N6O5S	FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2	InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide			N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide	C13H10ClF3N6O5S	FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2	InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide			N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide	C13H10ClF3N6O5S	FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2	InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide			N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide	C13H10ClF3N6O5S	FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2	InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide			N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide	C13H10ClF3N6O5S	FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2	InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide			N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide	C13H10ClF3N6O5S	FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2	InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide			N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide	C13H10ClF3N6O5S	FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2	InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide			N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide	C13H10ClF3N6O5S	FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2	InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide			N-(6-chloro-7-hydroxy-5-methoxy[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	N-(6-chloro-7-hydroxy-5-methoxy [1,2,4] triazolo[1,5-a]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl) pyridine -3-sulfonamide	C13H10ClF3N6O5S	FC(F)(F)c1ccnc(OC)c1S(=O)(=O)Nc2nc3nc(OC)c(Cl)c(O)n3n2	InChI=1S/C13H10ClF3N6O5S/c1-27-8-6(14)10(24)23-12(19-8)20-11(21-23)22-29(25,26)7-5(13(15,16)17)3-4-18-9(7)28-2/h3-4,24H,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)-3-pyridinesulfonic acid			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonic acid	Not in list	C7H6F3NO4S	COc1nccc(c1S(=O)(=O)O)C(F)(F)F	InChI=1S/C7H6F3NO4S/c1-15-6-5(16(12,13)14)4(2-3-11-6)7(8,9)10/h2-3H,1H3,(H,12,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is a metabolite of the substance	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide			2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	2-Methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	C7H7F3N2O3S	COc1nccc(c1S(N)(=O)=O)C(F)(F)F	InChI=1S/C7H7F3N2O3S/c1-15-6-5(16(11,13)14)4(2-3-12-6)7(8,9)10/h2-3H,1H3,(H2,11,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Ambiguous			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is identical to the substance	Prothioconazole		178928-70-6	2-[2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-1,2, 4-triazole-3-thione	Prothioconazole	C14H15Cl2N3OS	C1CC1(C(CC2=CC=CC=C2Cl)(CN3C(=S)N=CN3)O)Cl	InChI=1S/C14H15Cl2N3OS/c15-11-4-2-1-3-10(11)7-14(20,13(16)5-6-13)8-19-12(21)17-9-18-19/h1-4,9,20H,5-8H2,(H,17,18,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid			1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid	Not in list	C15H16Cl2N2O4S	OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3	InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid			1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid	Not in list	C15H16Cl2N2O4S	OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3	InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid			1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid	Not in list	C15H16Cl2N2O4S	OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3	InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid			1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid	Not in list	C15H16Cl2N2O4S	OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3	InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid			1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid	Not in list	C15H16Cl2N2O4S	OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3	InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid			1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid	Not in list	C15H16Cl2N2O4S	OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3	InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid			1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid	Not in list	C15H16Cl2N2O4S	OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3	InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid			1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid	Not in list	C15H16Cl2N2O4S	OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3	InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid			1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid	Not in list	C15H16Cl2N2O4S	OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3	InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1Hpyrazole-5-sulfonic acid			1-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1H-pyrazole-5-sulfonic acid	Not in list	C15H16Cl2N2O4S	OC(Cn1nccc1S(=O)(=O)O)(Cc2ccccc2Cl)C3(Cl)CC3	InChI=1S/C15H16Cl2N2O4S/c16-12-4-2-1-3-11(12)9-15(20,14(17)6-7-14)10-19-13(5-8-18-19)24(21,22)23/h1-5,8,20H,6-7,9-10H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one			2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C14H15Cl2N3O2	O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one			2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C14H15Cl2N3O2	O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one			2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C14H15Cl2N3O2	O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one			2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C14H15Cl2N3O2	O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one			2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C14H15Cl2N3O2	O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one			2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C14H15Cl2N3O2	O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one			2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C14H15Cl2N3O2	O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one			2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C14H15Cl2N3O2	O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one			2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C14H15Cl2N3O2	O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	1-(2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl)-1H-1,2,4-triazol-5(4H)-one			2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one	Not in list	C14H15Cl2N3O2	O=C3NC=NN3CC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)7-14(21,13(16)5-6-13)8-19-12(20)17-9-18-19/h1-4,9,21H,5-8H2,(H,17,18,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol	Not in list	C14H15Cl2N3O2	OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3	InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol	Not in list	C14H15Cl2N3O2	OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3	InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol	Not in list	C14H15Cl2N3O2	OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3	InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol	Not in list	C14H15Cl2N3O2	OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3	InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol	Not in list	C14H15Cl2N3O2	OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3	InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol	Not in list	C14H15Cl2N3O2	OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3	InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol	Not in list	C14H15Cl2N3O2	OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3	InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol	Not in list	C14H15Cl2N3O2	OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3	InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol	Not in list	C14H15Cl2N3O2	OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3	InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propane-1,2-diol	Not in list	C14H15Cl2N3O2	OC(Cn1cncn1)(C(O)c2ccccc2Cl)C3(Cl)CC3	InChI=1/C14H15Cl2N3O2/c15-11-4-2-1-3-10(11)12(20)14(21,13(16)5-6-13)7-19-9-17-8-18-19/h1-4,8-9,12,20-21H,5-7H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate	Not in list	C16H17Cl2N3O3	OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3	InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate	Not in list	C16H17Cl2N3O3	OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3	InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate	Not in list	C16H17Cl2N3O3	OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3	InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate	Not in list	C16H17Cl2N3O3	OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3	InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate	Not in list	C16H17Cl2N3O3	OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3	InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate	Not in list	C16H17Cl2N3O3	OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3	InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate	Not in list	C16H17Cl2N3O3	OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3	InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate	Not in list	C16H17Cl2N3O3	OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3	InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate	Not in list	C16H17Cl2N3O3	OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3	InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate			2-(1-chlorocyclopropyl)-1-(2-chlorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl acetate	Not in list	C16H17Cl2N3O3	OC(Cn1cncn1)(C(OC(C)=O)c2ccccc2Cl)C3(Cl)CC3	InChI=1S/C16H17Cl2N3O3/c1-11(22)24-14(12-4-2-3-5-13(12)17)16(23,15(18)6-7-15)8-21-10-19-9-20-21/h2-5,9-10,14,23H,6-8H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol			2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol	Not in list	C12H14Cl2O2	OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol			2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol	Not in list	C12H14Cl2O2	OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol			2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol	Not in list	C12H14Cl2O2	OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol			2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol	Not in list	C12H14Cl2O2	OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol			2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol	Not in list	C12H14Cl2O2	OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol			2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol	Not in list	C12H14Cl2O2	OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol			2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol	Not in list	C12H14Cl2O2	OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol			2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol	Not in list	C12H14Cl2O2	OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol			2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol	Not in list	C12H14Cl2O2	OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Prothioconazole		178928-70-6	single chemical entity	Component is a metabolite of the substance	2-(1-Chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol			2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)propane-1,2-diol	Not in list	C12H14Cl2O2	OCC(O)(Cc1ccccc1Cl)C2(Cl)CC2	InChI=1S/C12H14Cl2O2/c13-10-4-2-1-3-9(10)7-12(16,8-15)11(14)5-6-11/h1-4,15-16H,5-8H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Prothioconazole (JAU 6476)	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance prothioconazole	01Aug2007	2007	doi:10.2903/j.efsa.2007.106r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	without	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	with	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is identical to the substance	Penoxsulam (DE 638)		219714-96-2	2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Penoxsulam	C16H14F5N5O5S	COC1=CN=C(N2C1=NC(=N2)NS(=O)(=O)C3=C(C=CC=C3OCC(F)F)C(F)(F)F)OC	InChI=1S/C16H14F5N5O5S/c1-29-10-6-22-15(30-2)26-13(10)23-14(24-26)25-32(27,28)12-8(16(19,20)21)4-3-5-9(12)31-7-11(17)18/h3-6,11H,7H2,1-2H3,(H,24,25)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Italy	Penoxsulam (DE-638)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(5-hydroxy-8-methoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C15H12F5N5O5S	FC(F)(F)c1cccc(OCC(F)F)c1S(=O)(=O)Nc2nc3c(cnc(O)n3n2)OC	InChI=1S/C15H12F5N5O5S/c1-29-9-5-21-14(26)25-12(9)22-13(23-25)24-31(27,28)11-7(15(18,19)20)3-2-4-8(11)30-6-10(16)17/h2-5,10H,6H2,1H3,(H,21,26)(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	3-({[2-(2,2-Difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid			3-({[2-(2,2-difluoroethoxy)-6-(trifluoromethyl)phenyl]sulfonyl}amino)-1H-1,2,4-triazole-5-carboxylic acid	Not in list	C11H9F5N4O5S	OC(=O)c1nnc(NS(=O)(=O)c2c(OCC(F)F)cccc2C(F)(F)F)[nH]1	InChI=1S/C12H9F5N4O5S/c13-7(14)4-26-6-3-1-2-5(12(15,16)17)8(6)27(24,25)21-11-18-9(10(22)23)19-20-11/h1-3,7H,4H2,(H,22,23)(H2,18,19,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Penoxsulam		219714-96-2	single chemical entity	Component is a metabolite of the substance	2-(2,2-Difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide			2-(2,2-difluoroethoxy)-N-(1H-1,2,4-triazol-3-yl)-6-(trifluoromethyl)benzenesulfonamide	Not in list	C11H9F5N4O3S	O=S(=O)(Nc1ncnn1)c2c(cccc2OCC(F)F)C(F)(F)F	InChI=1/C11H9F5N4O3S/c12-8(13)4-23-7-3-1-2-6(11(14,15)16)9(7)24(21,22)20-10-17-5-18-19-10/h1-3,5,8H,4H2,(H2,17,18,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Penoxsulam (Final Addendum to the DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance penoxsulam	22Sep2009	2009	doi:10.2903/j.efsa.2009.343r
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss		No data	Not reported			no data	not applicable	Negative		no evidence	RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mouse spot test	in vivo	Equivalent or similar to	OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test)	Yes	Acceptable	House mouse (as animal)	C57BL		Male/Female	oral: unspecified			no data	not applicable	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is identical to the substance	Pyridate	259-686-7	55512-33-9	O-6-chloro-3-phenylpyridazin-4-yl S-octyl thiocarbonate	Pyridate	C19H23CIN2O2S	CCCCCCCCSC(=O)OC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C19H23ClN2O2S/c1-2-3-4-5-6-10-13-25-19(23)24-16-14-17(20)21-22-18(16)15-11-8-7-9-12-15/h7-9,11-12,14H,2-6,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No data	Acceptable	Rat (as animal)	Fischer344		No data	oral: unspecified			no data	not applicable	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	Pyridafol	254-752-1	40020-01-7	6-chloro-3-phenylpyridazin-4-ol	CL 9673 (6-chloro-4-hydroxy-3-phenylpyridazin)	C10H7ClN2O	C1=CC=C(C=C1)C2=NN=C(C=C2O)Cl	InChI=1S/C10H7ClN2O/c11-9-6-8(14)10(13-12-9)7-4-2-1-3-5-7/h1-6H,(H,12,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methoxy-3-phenylpyridazine		40020-02-8	6-chloro-4-methoxy-3-phenylpyridazine	Not in list	C11H9ClN2O	COC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methoxy-3-phenylpyridazine		40020-02-8	6-chloro-4-methoxy-3-phenylpyridazine	Not in list	C11H9ClN2O	COC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methoxy-3-phenylpyridazine		40020-02-8	6-chloro-4-methoxy-3-phenylpyridazine	Not in list	C11H9ClN2O	COC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methoxy-3-phenylpyridazine		40020-02-8	6-chloro-4-methoxy-3-phenylpyridazine	Not in list	C11H9ClN2O	COC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methoxy-3-phenylpyridazine		40020-02-8	6-chloro-4-methoxy-3-phenylpyridazine	Not in list	C11H9ClN2O	COC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methoxy-3-phenylpyridazine		40020-02-8	6-chloro-4-methoxy-3-phenylpyridazine	Not in list	C11H9ClN2O	COC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methoxy-3-phenylpyridazine		40020-02-8	6-chloro-4-methoxy-3-phenylpyridazine	Not in list	C11H9ClN2O	COC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methoxy-3-phenylpyridazine		40020-02-8	6-chloro-4-methoxy-3-phenylpyridazine	Not in list	C11H9ClN2O	COC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methoxy-3-phenylpyridazine		40020-02-8	6-chloro-4-methoxy-3-phenylpyridazine	Not in list	C11H9ClN2O	COC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Pyridate	259-686-7	55512-33-9	single chemical entity	Component is a metabolite of the substance	6-chloro-4-methoxy-3-phenylpyridazine		40020-02-8	6-chloro-4-methoxy-3-phenylpyridazine	Not in list	C11H9ClN2O	COC1=CC(=NN=C1C2=CC=CC=C2)Cl	InChI=1S/C11H9ClN2O/c1-15-9-7-10(12)13-14-11(9)8-5-3-2-4-6-8/h2-7H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria - CoRMS: Latvia	Pyridate (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridate	08Aug2014	2014	doi:10.2903/j.efsa.2014.3801
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is identical to the substance	Prosulfuron		94125-34-5	1-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-3-[2-(3,3,3-trifluoropropyl)phenylsulfonyl]urea	Prosulfuron	C15H16F3N5O4S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2CCC(F)(F)F	InChI=1S/C15H16F3N5O4S/c1-9-19-12(22-14(20-9)27-2)21-13(24)23-28(25,26)11-6-4-3-5-10(11)7-8-15(16,17)18/h3-6H,7-8H2,1-2H3,(H2,19,20,21,22,23,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative		no evidence	RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide			N-(carbamimidoylcarbamoyl)-2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C11H13F3N4O3S	O=S(=O)(NC(=O)NC(=N)N)c1ccccc1CCC(F)(F)F	InChI=1S/C11H13F3N4O3S/c12-11(13,14)6-5-7-3-1-2-4-8(7)22(20,21)18-10(19)17-9(15)16/h1-4H,5-6H2,(H5,15,16,17,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	small colonies		RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	10	Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	10	Male	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Prosulfuron		94125-34-5	single chemical entity	Component is a metabolite of the substance	2-(3,3,3-trifluoropropyl)benzenesulfonamide			2-(3,3,3-trifluoropropyl)benzenesulfonamide	Not in list	C9H10F3NO2S	C1=CC=C(C(=C1)CCC(F)(F)F)S(=O)(=O)N	InChI=1S/C9H10F3NO2S/c10-9(11,12)6-5-7-3-1-2-4-8(7)16(13,14)15/h1-4H,5-6H2,(H2,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France - CoRMS: Slovakia	Prosulfuron	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prosulfuron	02Sep2014	2014	doi:10.2903/j.efsa.2014.3815
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Positive			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	Not reported	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is identical to the substance	Pyridalyl		179101-81-6	2,6-dichloro-4-(3,3-dichloroallyloxy)phenyl 3-[5-(trifluoromethyl)-2-pyridyloxy]propyl ether	Pyridalyl	C18H14Cl4F3NO3	C1=CC(=NC(=C1)OCCCOC2=C(C=C(C=C2Cl)OCC=C(Cl)Cl)Cl)C(F)(F)F	InChI=1S/C18H14Cl4F3NO3/c19-12-9-11(27-8-5-15(21)22)10-13(20)17(12)29-7-2-6-28-16-4-1-3-14(26-16)18(23,24)25/h1,3-5,9-10H,2,6-8H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	Not reported	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Positive			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Positive			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	4	Male	Not reported	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	5-(Trifluoromethyl)-2(1H)-pyridinone		33252-63-0	5-(Trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H4F3NO	C1=CC(=O)NC=C1C(F)(F)F	InChI=1S/C6H4F3NO/c7-6(8,9)4-1-2-5(11)10-3-4/h1-3H,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	4	Male	Not reported	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Positive			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Positive			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Positive			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Positive			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Pyridalyl		179101-81-6	single chemical entity	Component is a metabolite of the substance	3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one			3-hydroxy-5-(trifluoromethyl)pyridin-2(1H)-one	Not in list	C6H4F3NO2	OC1=CC(=CNC1=O)C(F)(F)F	InChI=1S/C6H4F3NO2/c7-6(8,9)3-1-4(11)5(12)10-2-3/h1-2,11H,(H,10,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	Pyridalyl (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyridalyl.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3240
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Chinese	15	Female	intraperitoneal	2.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Wistar	10	Male	oral: gavage			yes, concurrent vehicle	not applicable	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Wistar	15	Male	oral: gavage	5.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Oryzalin	242-777-0	19044-88-3	single chemical entity	Component is identical to the substance	Oryzalin	242-777-0	19044-88-3	4-(dipropylamino)-3,5-dinitrobenzenesulfonamide	Oryzalin	C12H18N4O6S	[O-][N+](=O)c1cc(cc([N+]([O-])=O)c1N(CCC)CCC)S(N)(=O)=O	InChI=1S/C12H18N4O6S/c1-3-5-14(6-4-2)12-10(15(17)18)7-9(23(13,21)22)8-11(12)16(19)20/h7-8H,3-6H2,1-2H3,(H2,13,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oryzalin (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oryzalin.	03Sep2010	2010	doi:10.2903/j.efsa.2010.1707
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	RAW 264.7			Not reported			no data	no data	Positive			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL	30	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL	30	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is identical to the substance	Lambda-cyhalothrin	415-130-7	91465-08-6	[Cyano-(3-phenoxyphenyl)methyl] 3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropane-1-carboxylate	Lambda-Cyhalothrin	C23H19ClF3NO3	C1([C@H]([C@H]1C(O[C@@H](c1cc(Oc2ccccc2)ccc1)C#N)=O)\C=C(\C(F)(F)F)Cl)(C)C	InChI=1S/C23H19ClF3NO3/c1-22(2)17(12-19(24)23(25,26)27)20(22)21(29)31-18(13-28)14-7-6-10-16(11-14)30-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/b19-12-/t17-,18+,20-/m0/s1	organic	representative isomer	ChemIDPlus	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL	30	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Positive			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Positive			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1RS)-2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl (1RS,3RS)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylate			2-amino-2-oxo-1-(3-phenoxyphenyl)ethyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropane-1-carboxylate	Not in list	C23H21ClF3NO4	Cl\C(=C/C3C(C(=O)OC(c2cccc(Oc1ccccc1)c2)C(N)=O)C3(C)C)C(F)(F)F	InChI=1S/C23H21ClF3NO4/c1-22(2)16(12-17(24)23(25,26)27)18(22)21(30)32-19(20(28)29)13-7-6-10-15(11-13)31-14-8-4-3-5-9-14/h3-12,16,18-19H,1-2H3,(H2,28,29)/b17-12-	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(2RS)-hydroxy(3-phenoxyphenyl)acetonitrile			hydroxy(3-phenoxyphenyl)acetonitrile	Not in list	C14H11NO2	N#CC(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H11NO2/c15-10-14(16)11-5-4-8-13(9-11)17-12-6-2-1-3-7-12/h1-9,14,16H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(3-phenoxyphenyl)methanol	237-525-1	13826-35-2	(3-phenoxyphenyl)methanol	Not in list	C13H12O2	C1=CC=C(C=C1)OC2=CC=CC(=C2)CO	InChI=1S/C13H12O2/c14-10-11-5-4-8-13(9-11)15-12-6-2-1-3-7-12/h1-9,14H,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	hydroxy(3-phenoxyphenyl)acetic acid			hydroxy(3-phenoxyphenyl)acetic acid	Not in list	C14H12O4	O=C(O)C(O)c2cc(Oc1ccccc1)ccc2	InChI=1S/C14H12O4/c15-13(14(16)17)10-5-4-8-12(9-10)18-11-6-2-1-3-7-11/h1-9,13,15H,(H,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	44.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	44.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1S,3S)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@@H]1[C@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	68.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Lambda-cyhalothrin	415-130-7	91465-08-6	single chemical entity	Component is a metabolite of the substance	(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propen-1-yl]-2,2-dimethylcyclopropanecarboxylic acid			(1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylic acid	Not in list	C9H10ClF3O2	Cl\C(=C/[C@H]1[C@@H](C(=O)O)C1(C)C)C(F)(F)F	InChI=1/C9H10ClF3O2/c1-8(2)4(6(8)7(14)15)3-5(10)9(11,12)13/h3-4,6H,1-2H3,(H,14,15)/b5-3-/t4-,6-/m0/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	68.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden - CoRMS: Spain	Lambda-Cyhalothrin	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lambda-cyhalothrin	13May2014	2014	doi:10.2903/j.efsa.2014.3677
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	House mouse (as animal)	B6C3F1	3	Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is identical to the substance	Pymetrozine		123312-89-0	6-methyl-4-[(E)-pyridin-3-ylmethylideneamino]-2,5-dihydro-1,2,4-triazin-3-one	Pymetrozine	C10H11N5O	CC1=NNC(=O)N(C1)N=CC2=CN=CC=C2	InChI=1S/C10H11N5O/c1-8-7-15(10(16)14-13-8)12-6-9-3-2-4-11-5-9/h2-6H,7H2,1H3,(H,14,16)/b12-6+	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	House mouse (as animal)	B6C3F1	3	Male	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Positive			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Positive			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Positive			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one			4-amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one	Not in list	C4H8N4O	O=C1NN=C(C)CN1N	InChI=1S/C4H8N4O/c1-3-2-8(5)4(9)7-6-3/h2,5H2,1H3,(H,7,9)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	B6C3F1	4	Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	B6C3F1	4	Male	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	House mouse (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	5	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Pymetrozine		123312-89-0	single chemical entity	Component is a metabolite of the substance	nicotinaldehyde	207-900-4		pyridine-3-carbaldehyde	Not in list	C6H5NO	C1=CC(=CN=C1)C=O	InChI=1S/C6H5NO/c8-5-6-2-1-3-7-4-6/h1-5H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany - CoRMS: Belgium	Pymetrozine (Final Addendum to the DAR)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pymetrozine	09Sep2014	2014	doi:10.2903/j.efsa.2014.3817
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	without	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	with	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Positive		indirect evidence-systemic toxicity	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive		no evidence	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Hamster (as animal)	Chinese	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive		direct evidence-cytotoxicity	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Hamster (as animal)	Chinese	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propaquizafop		111479-05-1	single chemical entity	Component is identical to the substance	Propaquizafop		111479-05-1	2-[(propan-2-ylideneamino)oxy]ethyl (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoate	Propaquizafop	C22H22ClN3O5	C/C(C)=N\OCCOC(=O)[C@@H](C)Oc1ccc(cc1)Oc2cnc3cc(Cl)ccc3n2	InChI=1S/C22H22ClN3O5/c1-14(2)26-29-11-10-28-22(27)15(3)30-17-5-7-18(8-6-17)31-21-13-24-20-12-16(23)4-9-19(20)25-21/h4-9,12-13,15H,10-11H2,1-3H3/t15-/m1/s1	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Italy	Propaquizafop	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of propaquizafop (an ester variant of quizalofop-P)	17Mar2009	2009	doi:10.2903/j.efsa.2009.204r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	36.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CFLP	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	6	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	6	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Propamocarb hydrochloride	247-125-9	25606-41-1	single chemical entity	Component is identical to the substance	Propamocarb hydrochloride	247-125-9	25606-41-1	Dimethyl-[3-(propoxycarbonylamino)propyl]azanium;chloride	N-desmethyl propamocarb	C9H21ClN2O2	CCCOC(=O)NCCC[NH+](C)C.[Cl-]	InChI=1S/C9H20N2O2.ClH/c1-4-8-13-9(12)10-6-5-7-11(2)3;/h4-8H2,1-3H3,(H,10,12);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	ICR	25	Male	oral: drinking water	8.0000000000	week	yes	not applicable	Negative			RMS: Ireland	Propamocarb	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance propamocarb	05Jul2006	2006	doi:10.2903/j.efsa.2006.78r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	NMRI		No data	oral: gavage			no data	not applicable	Negative		no evidence	RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	Chinese		Male	oral: unspecified			no data	not applicable	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI		Female	oral: gavage			yes	not applicable	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI		Female	oral: gavage			yes	not applicable	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is identical to the substance	Metribuzin	244-209-7	21087-64-9	4-Amino-6-tert-butyl-3-methylsulfanyl-1,2,4-triazin-5-one	Metribuzin	C8H14N4OS	CC(C)(C)C1=NN=C(N(C1=O)N)SC	InChI=1S/C8H14N4OS/c1-8(2,3)5-6(13)12(9)7(14-4)11-10-5/h9H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	NMRI		Male	oral: gavage			yes	not applicable	Negative			RMS: Germany	Metribuzin	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Metribuzin	244-209-7	21087-64-9	single chemical entity	Component is a metabolite of the substance	desaminodiketo-metribuzin			6-tert-butyl-2H-1,2,4-triazine-3,5-dione	Not in list	C7H11N3O2	CC(C)(C)C1=NNC(=O)NC1=O	InChI=1S/C7H11N3O2/c1-7(2,3)4-5(11)8-6(12)10-9-4/h1-3H3,(H2,8,10,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Germany	Metribuzin (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metribuzin	18Sep2006	2006	doi:10.2903/j.efsa.2006.88r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	fibroblast			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	fibroblast			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	fibroblast			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	fibroblast			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	fibroblast			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	fibroblast			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	fibroblast			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	fibroblast			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CF-1	5	Male	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		no evidence	RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	16.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	16.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	16.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	16.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	16.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	16.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: unspecified	16.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Hamster (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Hamster (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Hamster (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Hamster (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Hamster (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Hamster (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Hamster (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is the active ingredient of the mixture or formulation	Prochloraz-Copper		156065-03-1	Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II)	Not in list	C60H64Cl14CuN12O8			organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is the active ingredient of the mixture or formulation	Prochloraz-Copper		156065-03-1	Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II)	Not in list	C60H64Cl14CuN12O8			organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is the active ingredient of the mixture or formulation	Prochloraz-Copper		156065-03-1	Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II)	Not in list	C60H64Cl14CuN12O8			organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is the active ingredient of the mixture or formulation	Prochloraz-Copper		156065-03-1	Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II)	Not in list	C60H64Cl14CuN12O8			organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is the active ingredient of the mixture or formulation	Prochloraz-Copper		156065-03-1	Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II)	Not in list	C60H64Cl14CuN12O8			organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is the active ingredient of the mixture or formulation	Prochloraz-Copper		156065-03-1	Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II)	Not in list	C60H64Cl14CuN12O8			organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is the active ingredient of the mixture or formulation	Prochloraz-Copper		156065-03-1	Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II)	Not in list	C60H64Cl14CuN12O8			organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is the active ingredient of the mixture or formulation	Prochloraz-Copper		156065-03-1	Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II)	Not in list	C60H64Cl14CuN12O8			organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is the active ingredient of the mixture or formulation	Prochloraz-Copper		156065-03-1	Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II)	Not in list	C60H64Cl14CuN12O8			organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is the active ingredient of the mixture or formulation	Prochloraz-Copper		156065-03-1	Dichlorotetrakids-[N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl] imidazole-1-carboxamide]copper(II)	Not in list	C60H64Cl14CuN12O8			organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	no information		RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	CD-1	20	Male	oral: feed	8.0000000000	week	yes	not applicable	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea			1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea	Not in list	C12H15Cl3N2O2	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N	InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18)	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea			1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea	Not in list	C12H15Cl3N2O2	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N	InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18)	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea			N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide	Not in list	C13H15Cl3N2O3	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O	InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea			N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide	Not in list	C13H15Cl3N2O3	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O	InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea			1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea	Not in list	C12H15Cl3N2O2	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N	InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18)	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea			N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide	Not in list	C13H15Cl3N2O3	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O	InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea			1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea	Not in list	C12H15Cl3N2O2	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N	InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18)	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea			N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide	Not in list	C13H15Cl3N2O3	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O	InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea			N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide	Not in list	C13H15Cl3N2O3	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O	InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea			1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea	Not in list	C12H15Cl3N2O2	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N	InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18)	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea			N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide	Not in list	C13H15Cl3N2O3	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O	InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea			N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide	Not in list	C13H15Cl3N2O3	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O	InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea			1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea	Not in list	C12H15Cl3N2O2	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N	InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18)	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea			1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea	Not in list	C12H15Cl3N2O2	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N	InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18)	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea			N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide	Not in list	C13H15Cl3N2O3	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O	InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea			N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide	Not in list	C13H15Cl3N2O3	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O	InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	3-Formyl-1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea			N-[propyl-[2-(2,4,6-trichlorophenoxy)ethyl]carbamoyl]formamide	Not in list	C13H15Cl3N2O3	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)NC=O	InChI=1S/C13H15Cl3N2O3/c1-2-3-18(13(20)17-8-19)4-5-21-12-10(15)6-9(14)7-11(12)16/h6-8H,2-5H2,1H3,(H,17,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea			1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea	Not in list	C12H15Cl3N2O2	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N	InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18)	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea			1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea	Not in list	C12H15Cl3N2O2	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N	InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18)	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is a metabolite of the substance	1-Propyl-1-[2-(2,4,6 trichlorophenoxy)ethyl]urea			1-Propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea	Not in list	C12H15Cl3N2O2	CCCN(CCOC1=C(C=C(C=C1Cl)Cl)Cl)C(=O)N	InChI=1S/C12H15Cl3N2O2/c1-2-3-17(12(16)18)4-5-19-11-9(14)6-8(13)7-10(11)15/h6-7H,2-5H2,1H3,(H2,16,18)	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Prochloraz	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			no data	with	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Positive			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No data	Acceptable	Rat (as animal)	Crj:CD(SD)		Male	oral: unspecified			no data	not applicable	Negative			RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Prochloraz	266-994-5	67747-09-5	single chemical entity	Component is identical to the substance	Prochloraz	266-994-5	67747-09-5	N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-1H-imidazole-1-carboxamide	Prochloraz	C15H16Cl3N3O2	O=C(N(CCOc1c(Cl)cc(Cl)cc1Cl)CCC)n2ccnc2	InChI=1S/C15H16Cl3N3O2/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18/h3,5,8-10H,2,4,6-7H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1		Male/Female	oral: unspecified			no data	not applicable	Negative		no evidence	RMS: Ireland	Prochloraz (Addendum)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance prochloraz	22Jul2011	2011	doi:10.2903/j.efsa.2011.2323
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	large colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	small colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No data	Acceptable	Rat (as animal)	Alpk:APf SD Rat	10	Male	oral: unspecified	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No data	Acceptable	Rat (as animal)	Alpk:APf SD Rat	10	Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is identical to the substance	Pirimicarb	245-430-1	23103-98-2	[2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl] N,N-dimethylcarbamate	Pirimicarb	C11H18N4O2	CC1=C(N=C(N=C1OC(=O)N(C)C)N(C)C)C	InChI=1S/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	CD-1	15	Male	oral: gavage	5.0000000000	D	yes	not applicable	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	large colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	small colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	5,6-dimethyl-2-(methylamino)pyrimidin-4-ol			5,6-dimethyl-2-(methylamino)pyrimidin-4-ol	Not in list	C7H11N3O	Cc1nc(NC)nc(O)c1C	InChI=1S/C7H11N3O/c1-4-5(2)9-7(8-3)10-6(4)11/h1-3H3,(H2,8,9,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	small colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	small colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	large colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	large colonies		RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	6	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	6	Male/Female	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimicarb	245-430-1	23103-98-2	single chemical entity	Component is a metabolite of the substance	2-dimethylamino-5,6-dimethylpyrimidin-4-ol			2-(dimethylamino)-5,6-dimethylpyrimidin-4-ol	Not in list	C8H13N3O	Cc1nc(nc(O)c1C)N(C)C	InChI=1S/C8H13N3O/c1-5-6(2)9-8(11(3)4)10-7(5)12/h1-4H3,(H,9,10,12)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pirimicarb	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance pirimicarb	31Aug2005	2005	doi:10.2903/j.efsa.2005.43r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	fibroblast			Not reported			yes	with	Ambiguous			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	fibroblast			Not reported			yes	without	Ambiguous			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	fibroblast			Not reported			yes	with	Positive			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	5	Male	oral: gavage	16.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	5	Male	oral: gavage	2.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	CD-1	15	Male	oral: gavage	5.0000000000	D	yes	not applicable	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Positive			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Positive			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			no data	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			no data	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA1532			Not reported			no data	without	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			no data	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			no data	without	Positive			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			no data	without	Positive			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			no data	with	Positive			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			no data	with	Positive			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	TA1532			Not reported			no data	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			no data	with	Negative			RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Swiss		Male	oral: unspecified	6.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Pirimiphos-methyl	249-528-5	29232-93-7	single chemical entity	Component is identical to the substance	Pirimiphos-methyl	249-528-5	29232-93-7	O-[2-(diethylamino)-6-methylpyrimidin-4-yl] O,O-dimethyl thiophosphate	Pirimiphos-methyl	C11H20N3O3PS	CCN(CC)c1nc(C)cc(OP(=S)(OC)OC)n1	InChI=1/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	ICR	4	Female	Not reported			yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Pirimiphos-methyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance pirimiphos-methyl	31Aug2005	2005	doi:10.2903/j.efsa.2005.44r
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: unspecified	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is identical to the substance	Isoxaflutole	604-222-4	141112-29-0	(5-cyclopropyl-1,2-oxazol-4-yl)-[2-methylsulfonyl-4-(trifluoromethyl)phenyl]methanone	Isoxaflutole	C15H12F3NO4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)C2=C(ON=C2)C3CC3	InChI=1S/C15H12F3NO4S/c1-24(21,22)12-6-9(15(16,17)18)4-5-10(12)13(20)11-7-19-23-14(11)8-2-3-8/h4-8H,2-3H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	(2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile			3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile	Not in list	C15H12F3NO4S	O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F	InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	(2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile			3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile	Not in list	C15H12F3NO4S	O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F	InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	(2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile			3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile	Not in list	C15H12F3NO4S	O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F	InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	(2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile			3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile	Not in list	C15H12F3NO4S	O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F	InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	(2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile			3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile	Not in list	C15H12F3NO4S	O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F	InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	(2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile			3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile	Not in list	C15H12F3NO4S	O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F	InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	(2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile			3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile	Not in list	C15H12F3NO4S	O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F	InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	(2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile			3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile	Not in list	C15H12F3NO4S	O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F	InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	(2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile			3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile	Not in list	C15H12F3NO4S	O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F	InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	(2RS)-3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile			3-cyclopropyl-2-[2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl]-3-oxopropanenitrile	Not in list	C15H12F3NO4S	O=C(C(C#N)C(=O)C1CC1)c2ccc(cc2S(C)(=O)=O)C(F)(F)F	InChI=1S/C15H12F3NO4S/c1-24(22,23)12-6-9(15(16,17)18)4-5-10(12)14(21)11(7-19)13(20)8-2-3-8/h4-6,8,11H,2-3H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Isoxaflutole	604-222-4	141112-29-0	single chemical entity	Component is a metabolite of the substance	2-mesyl-4-trifluoromethylbenzoic acid		142994-06-7	2-methylsulfonyl-4-(trifluoromethyl)benzoic acid	Not in list	C9H7F3O4S	CS(=O)(=O)C1=C(C=CC(=C1)C(F)(F)F)C(=O)O	InChI=1S/C9H7F3O4S/c1-17(15,16)7-4-5(9(10,11)12)2-3-6(7)8(13)14/h2-4H,1H3,(H,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy - CoRMS: Slovenia	Isoxaflutole	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance isoxaflutole	24Feb2016	2016	doi:10.2903/j.efsa.2016.4416
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	small colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	large colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	3	Male	Not reported	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is identical to the substance	Pinoxaden		243973-20-8	[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate	Pinoxaden	C23H32N2O4	CCC1=CC(=CC(=C1C2=C(N3CCOCCN3C2=O)OC(=O)C(C)(C)C)CC)C	InChI=1S/C23H32N2O4/c1-7-16-13-15(3)14-17(8-2)18(16)19-20(26)24-9-11-28-12-10-25(24)21(19)29-22(27)23(4,5)6/h13-14H,7-12H2,1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	3	Male	Not reported	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	3	No data	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (NOA 447204)			8-(2,6-diethyl-4-methyl-phenyl)-8-hydroxy -tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepine-7,9-dione	Not in list	C18H24N2O4	CCc1cc(C)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O4/c1-4-13-10-12(3)11-14(5-2)15(13)18(23)16(21)19-6-8-24-9-7-20(19)17(18)22/h10-11,23H,4-9H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	3	No data	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 502836)			3,5-diethyl-4-(9-hydroxy-7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin-8-yl)benzoic acid	Not in list	C18H22N2O5	O=C(O)c3cc(CC)c(C=2C(=O)N1CCOCCN1C=2O)c(CC)c3	InChI=1S/C18H22N2O5/c1-3-11-9-13(18(23)24)10-12(4-2)14(11)15-16(21)19-5-7-25-8-6-20(19)17(15)22/h9-10,21H,3-8H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	large colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	small colonies		RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	35	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	35	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	3	Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pinoxaden		243973-20-8	single chemical entity	Component is a metabolite of the substance	Pinoxaden metabolite (SYN 505887)			8-[2,6-diethyl-4-(hydroxymethyl)phenyl]-8-hydroxytetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepine-7,9(8H)-dione	Not in list	C18H24N2O5	CCc1cc(CO)cc(CC)c1C3(O)C(=O)N2CCOCCN2C3=O	InChI=1S/C18H24N2O5/c1-3-13-9-12(11-21)10-14(4-2)15(13)18(24)16(22)19-5-7-25-8-6-20(19)17(18)23/h9-10,21,24H,3-8,11H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	3	Male	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Pinoxaden (NOA 407855)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pinoxaden.	16Aug2013	2013	doi:10.2903/j.efsa.2013.3269
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-proficient			Not reported			yes	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			yes	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-proficient			Not reported			yes	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			yes	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	Strain S211c S. cerevisiae			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	S138			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	genome mutation	other	in vitro	No guideline available	Not reported	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	genome mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	genome mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	genome mutation	other	in vitro	No guideline available	Not reported	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	Yes	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI		Male	oral: unspecified			yes	not applicable	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI		Male	oral: unspecified			yes	not applicable	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is identical to the substance	Pencycuron	266-096-3	66063-05-6	1-(4-chlorobenzyl)-1-cyclopentyl-3-phenylurea	Pencycuron	C19H21ClN2O	O=C(NC2=CC=CC=C2)N(C3CCCC3)CC1=CC=C(Cl)C=C1	InChI=1S/C19H21ClN2O/c20-16-12-10-15(11-13-16)14-22(18-8-4-5-9-18)19(23)21-17-6-2-1-3-7-17/h1-3,6-7,10-13,18H,4-5,8-9,14H2,(H,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is a metabolite of the substance	N-(4-chlorobenzyl)cyclopentanamine			N-(4-chlorobenzyl)cyclopentanamine	Not in list	C12H16ClN	Clc1ccc(cc1)CNC2CCCC2	InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is a metabolite of the substance	N-(4-chlorobenzyl)cyclopentanamine			N-(4-chlorobenzyl)cyclopentanamine	Not in list	C12H16ClN	Clc1ccc(cc1)CNC2CCCC2	InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is a metabolite of the substance	N-(4-chlorobenzyl)cyclopentanamine			N-(4-chlorobenzyl)cyclopentanamine	Not in list	C12H16ClN	Clc1ccc(cc1)CNC2CCCC2	InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is a metabolite of the substance	N-(4-chlorobenzyl)cyclopentanamine			N-(4-chlorobenzyl)cyclopentanamine	Not in list	C12H16ClN	Clc1ccc(cc1)CNC2CCCC2	InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is a metabolite of the substance	N-(4-chlorobenzyl)cyclopentanamine			N-(4-chlorobenzyl)cyclopentanamine	Not in list	C12H16ClN	Clc1ccc(cc1)CNC2CCCC2	InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is a metabolite of the substance	N-(4-chlorobenzyl)cyclopentanamine			N-(4-chlorobenzyl)cyclopentanamine	Not in list	C12H16ClN	Clc1ccc(cc1)CNC2CCCC2	InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is a metabolite of the substance	N-(4-chlorobenzyl)cyclopentanamine			N-(4-chlorobenzyl)cyclopentanamine	Not in list	C12H16ClN	Clc1ccc(cc1)CNC2CCCC2	InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is a metabolite of the substance	N-(4-chlorobenzyl)cyclopentanamine			N-(4-chlorobenzyl)cyclopentanamine	Not in list	C12H16ClN	Clc1ccc(cc1)CNC2CCCC2	InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is a metabolite of the substance	N-(4-chlorobenzyl)cyclopentanamine			N-(4-chlorobenzyl)cyclopentanamine	Not in list	C12H16ClN	Clc1ccc(cc1)CNC2CCCC2	InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Pencycuron	266-096-3	66063-05-6	single chemical entity	Component is a metabolite of the substance	N-(4-chlorobenzyl)cyclopentanamine			N-(4-chlorobenzyl)cyclopentanamine	Not in list	C12H16ClN	Clc1ccc(cc1)CNC2CCCC2	InChI=1S/C12H16ClN/c13-11-7-5-10(6-8-11)9-14-12-3-1-2-4-12/h5-8,12,14H,1-4,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Pencycuron (Final Addendum to the DAR)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pencycuron	04Oct2010	2010	doi:10.2903/j.efsa.2010.1828
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	4	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Inconclusive		direct evidence-cytotoxicity	RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is identical to the substance	Phosalone	218-996-2	2310-17-0	S-[(6-chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl dithiophosphate	Phosalone	C12H15ClNO4PS2	CCOP(=S)(OCC)SCN1C(=O)Oc2cc(Cl)ccc12	InChI=1/C12H15ClNO4PS2/c1-3-16-19(20,17-4-2)21-8-14-10-6-5-9(13)7-11(10)18-12(14)15/h5-7H,3-4,8H2,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	CD-1	10	Male	oral: gavage			yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Positive			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Positive			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Phosalone	218-996-2	2310-17-0	single chemical entity	Component is a metabolite of the substance	2-amino-7-chloro-3H-phenoxazin-3-one			2-amino-7-chloro-3H-phenoxazin-3-one	Not in list	C12H7ClN2O2	NC1=CC2=Nc3ccc(Cl)cc3OC2=CC1=O	InChI=1S/C12H7ClN2O2/c13-6-1-2-8-11(3-6)17-12-5-10(16)7(14)4-9(12)15-8/h1-5H,14H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Austria	Phosalone	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosalone	06Mar2006	2006	doi:10.2903/j.efsa.2006.60r
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is identical to the substance	Penflufen		494793-67-8	5-fluoro-1,3-dimethyl-N-[2-(4-methylpentan-2-yl)phenyl]-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O	O=C(Nc1ccccc1C(C)CC(C)C)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O/c1-11(2)10-12(3)14-8-6-7-9-15(14)20-18(23)16-13(4)21-22(5)17(16)19/h6-9,11-12H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	5-fluoro-N-[2-(3-hydroxy-1,3-dimethylbutyl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide			5-fluoro-N-[2-(4-hydroxy-4-methylpentan-2-yl)phenyl]-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C18H24FN3O2	O=C(Nc1ccccc1C(C)CC(C)(C)O)c2c(F)n(C)nc2C	InChI=1S/C18H24FN3O2/c1-11(10-18(3,4)24)13-8-6-7-9-14(13)20-17(23)15-12(2)21-22(5)16(15)19/h6-9,11,24H,10H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Penflufen		494793-67-8	single chemical entity	Component is a metabolite of the substance	N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide			N-(2-acetylphenyl)-5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide	Not in list	C14H14FN3O2	O=C(Nc1ccccc1C(C)=O)c2c(F)n(C)nc2C	InChI=1S/C14H14FN3O2/c1-8-12(13(15)18(3)17-8)14(20)16-11-7-5-4-6-10(11)9(2)19/h4-7H,1-3H3,(H,16,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Penflufen	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penflufen	21Aug2012	2012	doi:10.2903/j.efsa.2012.2860
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	60	Male/Female	oral: gavage	51.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	60	Male/Female	oral: gavage	27.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	60	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	20	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	20	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Oxyfluorfen	255-983-0	42874-03-3	single chemical entity	Component is identical to the substance	Oxyfluorfen	255-983-0	42874-03-3	2-chloro-1-(3-ethoxy-4-nitrophenoxy)-4-(trifluoromethyl)benzene	Oxyfluorfen	C15H11ClF3NO4	Clc2cc(ccc2Oc1ccc([N+]([O-])=O)c(OCC)c1)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-2-23-14-8-10(4-5-12(14)20(21)22)24-13-6-3-9(7-11(13)16)15(17,18)19/h3-8H,2H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Oxyfluorfen	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance oxyfluorfen	23Nov2010	2010	doi:10.2903/j.efsa.2010.1906
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Alderly Park Rat	16	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Alderly Park Rat	16	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Alderly Park Rat	16	Male/Female	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Alderly Park Rat	6	Male	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alderly Park Rat	5	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alderly Park Rat	5	Male	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is identical to the substance	Paclobutrazol		76738-62-0	1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pentan-3-ol	Paclobutrazol	C15H20ClN3O	OC(C(C)(C)C)C(CC(C=C1)=CC=C1Cl)N2N=CN=C2	InChI=1S/C15H20ClN3O/c1-15(2,3)14(20)13(19-10-17-9-18-19)8-11-4-6-12(16)7-5-11/h4-7,9-10,13-14,20H,8H2,1-3H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	CD-1	20	Male	oral: gavage	5.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Paclobutrazol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			no data	with	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Paclobutrazol		76738-62-0	single chemical entity	Component is a metabolite of the substance	Triazole lactic acid			2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole lactic acid	C5H7N3O3	OC(Cn1cncn1)C(=O)O	InChI=1S/C5H7N3O3/c9-4(5(10)11)1-8-3-6-2-7-8/h2-4,9H,1H2,(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			no data	without	Negative			Rms: The United Kingdom	Paclobutrazol (Additional Report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance paclobutrazol	04Nov2010	2010	doi:10.2903/j.efsa.2010.1876
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	24	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	24	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	[2-(dimethylcarbamoyl)phenyl] sulfamic acid			[2-(dimethylcarbamoyl)phenyl]sulfamic acid	Not in list	C9H12N2O4S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)O	InChI=1S/C9H12N2O4S/c1-11(2)9(12)7-5-3-4-6-8(7)10-16(13,14)15/h3-6,10H,1-2H3,(H,13,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	(4,6-dimethoxypyrimidin-2-yl)urea			1-(4,6-dimethoxypyrimidin-2-yl)urea	Not in list	C7H10N4O3	O=C(N)Nc1nc(cc(OC)n1)OC	InChI=1S/C7H10N4O3/c1-13-4-3-5(14-2)10-7(9-4)11-6(8)12/h3H,1-2H3,(H3,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-methoxy-6-hydroxypyrimidin-2-yl)-3-[2-(2-dimethylcarbamoyl)phenylsulfamoyl]urea			2-{[({[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]amino}oxy)sulfinyl]amino}-N,N-dimethylbenzamide	Not in list	C15H18N6O6S	O=C(Nc1nc(O)cc(OC)n1)NOS(=O)Nc2ccccc2C(=O)N(C)C	InChI=1S/C15H18N6O6S/c1-21(2)13(23)9-6-4-5-7-10(9)20-28(25)27-19-15(24)18-14-16-11(22)8-12(17-14)26-3/h4-8,20H,1-3H3,(H3,16,17,18,19,22,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Orthosulfamuron	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Positive			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Positive			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	no information		RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	no information		RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	no information		RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	no data	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	no data	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Alpk:APf SD Rat	5	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Alpk:APf SD Rat	5	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	AB/Jena Halle House mouse	6	Male	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	AB/Jena Halle House mouse	6	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	AB/Jena Halle House mouse	6	Male	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Phosmet	211-987-4	732-11-6	single chemical entity	Component is identical to the substance	Phosmet	211-987-4	732-11-6	S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate	Phosmet	C11H12NO4PS2	COP(=S)(OC)SCN1C(=O)c2ccccc2C1=O	InChI=1/C11H12NO4PS2/c1-15-17(18,16-2)19-7-12-10(13)8-5-3-4-6-9(8)11(12)14/h3-6H,7H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	AB/Jena Halle House mouse	6	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Spain	Phosmet	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance phosmet	21Jun2006	2006	doi:10.2903/j.efsa.2006.75r
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	Not reported			yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is identical to the substance	Penthiopyrad		183675-82-3	1-methyl-N-[2-(4-methylpentan-2-yl)thiophen-3-yl]-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Penthiopyrad	C16H20F3N3OS	O=C(Nc1ccsc1C(C)CC(C)C)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3OS/c1-9(2)7-10(3)13-12(5-6-24-13)20-15(23)11-8-22(4)21-14(11)16(17,18)19/h5-6,8-10H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Not reported		No data	Not reported			yes	not applicable	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid			5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H3F3N2O2	C1=NNC(=C1C(=O)O)C(F)(F)F	InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid			5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H3F3N2O2	C1=NNC(=C1C(=O)O)C(F)(F)F	InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid			5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H3F3N2O2	C1=NNC(=C1C(=O)O)C(F)(F)F	InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid			5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H3F3N2O2	C1=NNC(=C1C(=O)O)C(F)(F)F	InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid			5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H3F3N2O2	C1=NNC(=C1C(=O)O)C(F)(F)F	InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid			5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H3F3N2O2	C1=NNC(=C1C(=O)O)C(F)(F)F	InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid			5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H3F3N2O2	C1=NNC(=C1C(=O)O)C(F)(F)F	InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	3-Trifluoromethyl-1H-pyrazole-4-carboxylic acid			5-(Trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H3F3N2O2	C1=NNC(=C1C(=O)O)C(F)(F)F	InChI=1S/C5H3F3N2O2/c6-5(7,8)3-2(4(11)12)1-9-10-3/h1H,(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide	Not in list	C6H6F3N3O	CN1C=C(C(=N1)C(F)(F)F)C(=O)N	InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide	Not in list	C6H6F3N3O	CN1C=C(C(=N1)C(F)(F)F)C(=O)N	InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide	Not in list	C6H6F3N3O	CN1C=C(C(=N1)C(F)(F)F)C(=O)N	InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide	Not in list	C6H6F3N3O	CN1C=C(C(=N1)C(F)(F)F)C(=O)N	InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide	Not in list	C6H6F3N3O	CN1C=C(C(=N1)C(F)(F)F)C(=O)N	InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Positive			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide	Not in list	C6H6F3N3O	CN1C=C(C(=N1)C(F)(F)F)C(=O)N	InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide	Not in list	C6H6F3N3O	CN1C=C(C(=N1)C(F)(F)F)C(=O)N	InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Positive	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide	Not in list	C6H6F3N3O	CN1C=C(C(=N1)C(F)(F)F)C(=O)N	InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide	Not in list	C6H6F3N3O	CN1C=C(C(=N1)C(F)(F)F)C(=O)N	InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid			1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C6H5F3N2O2	FC(F)(F)c1nn(C)cc1C(=O)O	InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid			1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C6H5F3N2O2	FC(F)(F)c1nn(C)cc1C(=O)O	InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid			1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C6H5F3N2O2	FC(F)(F)c1nn(C)cc1C(=O)O	InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid			1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C6H5F3N2O2	FC(F)(F)c1nn(C)cc1C(=O)O	InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid			1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C6H5F3N2O2	FC(F)(F)c1nn(C)cc1C(=O)O	InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid			1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C6H5F3N2O2	FC(F)(F)c1nn(C)cc1C(=O)O	InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid			1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C6H5F3N2O2	FC(F)(F)c1nn(C)cc1C(=O)O	InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid			1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C6H5F3N2O2	FC(F)(F)c1nn(C)cc1C(=O)O	InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxylic acid			1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C6H5F3N2O2	FC(F)(F)c1nn(C)cc1C(=O)O	InChI=1S/C6H5F3N2O2/c1-11-2-3(5(12)13)4(10-11)6(7,8)9/h2H,1H3,(H,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	Not reported			no data	not applicable	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O2S	O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O2S	O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O2S	O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O2S	O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O2S	O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O2S	O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O2S	O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no	without	Negative	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[2-(3-hydroxy-1,3-dimethylbutyl) thiophen-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-(4-hydroxy-4-methylpentan-2-yl)thiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O2S	O=C(Nc1ccsc1C(C)CC(C)(C)O)c2cn(C)nc2C(F)(F)F	InChI=1S/C16H20F3N3O2S/c1-9(7-15(2,3)24)12-11(5-6-25-12)20-14(23)10-8-22(4)21-13(10)16(17,18)19/h5-6,8-9,24H,7H2,1-4H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no	with	Negative	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O3S	OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C	InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O3S	OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C	InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O3S	OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C	InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O3S	OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C	InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O3S	OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C	InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O3S	OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C	InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O3S	OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C	InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	N-[5-hydroxy-5-(1,3-dimethylbutyl)-2-oxo-2,5-dihydrothiophen-4-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			N-[2-hydroxy-2-(4-methylpentan-2-yl)-5-oxo-2,5-dihydrothiophen-3-yl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide	Not in list	C16H20F3N3O3S	OC2(SC(=O)C=C2NC(=O)c1cn(C)nc1C(F)(F)F)C(C)CC(C)C	InChI=1S/C16H20F3N3O3S/c1-8(2)5-9(3)15(25)11(6-12(23)26-15)20-14(24)10-7-22(4)21-13(10)16(17,18)19/h6-9,25H,5H2,1-4H3,(H,20,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: The United Kingdom	Penthiopyrad	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide	Not in list	C6H6F3N3O	CN1C=C(C(=N1)C(F)(F)F)C(=O)N	InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Penthiopyrad (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Penthiopyrad		183675-82-3	single chemical entity	Component is a metabolite of the substance	1-Methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide			1-Methyl-3-(trifluoromethyl)pyrazole-4-carboxamide	Not in list	C6H6F3N3O	CN1C=C(C(=N1)C(F)(F)F)C(=O)N	InChI=1S/C6H6F3N3O/c1-12-2-3(5(10)13)4(11-12)6(7,8)9/h2H,1H3,(H2,10,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Penthiopyrad (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance penthiopyrad.	15Feb2013	2013	doi:10.2903/j.efsa.2013.3111
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-proficient			Not reported			yes	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-proficient			Not reported			yes	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			yes	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	K12			Not reported			yes	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-proficient			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	K12			Not reported			yes	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	K12			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	K12			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-proficient			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	DNA-polymerase-A-deficient			Not reported			yes	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	5	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is identical to the substance	Fosetyl-aluminium	254-320-2	39148-24-8	Aluminum;ethoxy-oxido-oxophosphanium	Fosetyl-aluminium	C6H15AlO9P3+3	CCO[P+](=O)[O-].CCO[P+](=O)[O-].CCO[P+](=O)[O-].[Al+3]	InChI=1S/3C2H5O3P.Al/c3*1-2-5-6(3)4;/h3*2H2,1H3;/q;;;+3	organometallic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1		Male	oral: unspecified			no data	not applicable	Negative		no evidence	RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1		Male	oral: unspecified			no data	not applicable	Negative		no evidence	RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	K12			Not reported			no data	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	K12			Not reported			no data	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	K12			Not reported			no data	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	K12			Not reported			no data	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Fosetyl-aluminium	254-320-2	39148-24-8	single chemical entity	Component is a metabolite of the substance	Phosphorous acid	233-663-1	10294-56-1	Phosphorous acid	Not in list	H3O3P	OP(O)O	InChI=1S/H3O3P/c1-4(2)3/h1-3H	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Fosetyl-Al	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fosetyl	18Jan2006	2006	doi:10.2903/j.efsa.2006.54r
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Potassium phosphite	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	5	Male	intraveneous	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Potassium phosphite (Addendum 1)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Potassium phosphonates			mixture or formulation	Component is identical to the substance	Potassium phosphonates			tripotassium;phosphite	Not in list	K3O3P	[O-]P([O-])[O-].[K+].[K+].[K+]	InChI=1S/3K.O3P/c;;;1-4(2)3/q3*+1;-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	5	Male	intraveneous	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Potassium phosphite (Addendum 1)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance potassium phosphonates	18Dec2012	2012	doi:10.2903/j.efsa.2012.2963
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	S138			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	S138			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	S211α			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	yeast cytogenetic assay	in vitro	Equivalent or similar to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	S211α			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Testis cell			Not reported			yes	without	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	no information		RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	no information		RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Inconclusive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No data	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	6.0000000000	h	yes	not applicable	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: unspecified	6.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	6.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mouse spot test	in vivo	Equivalent or similar to	OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test)	No data	Acceptable	House mouse (as animal)	C57BL		Male/Female	oral: unspecified			yes	not applicable	Positive			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	Not reported		Male	oral: unspecified			no data	not applicable	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	CD-1	20	Male	intraperitoneal			yes, concurrent vehicle	not applicable	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	CD-1	20	Male	intraperitoneal			yes, concurrent vehicle	not applicable	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	No data	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	4.0000000000	h	yes	not applicable	Negative			RMS: France	Oxydemeton-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Oxydemeton-methyl	206-110-7	301-12-2	single chemical entity	Component is identical to the substance	Oxydemeton-methyl	206-110-7	301-12-2	1-Dimethoxyphosphorylsulfanyl-2-ethylsulfinylethane	Oxydemeton-methyl	C6H15O4PS2	CCS(=O)CCSP(=O)(OC)OC	InChI=1S/C6H15O4PS2/c1-4-13(8)6-5-12-11(7,9-2)10-3/h4-6H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Oxydemeton-methyl (Final Addendum to the DAR)	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance oxydemeton-methyl	28Jul2006	2006	doi:10.2903/j.efsa.2006.86r
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male	oral: gavage	6.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male	oral: gavage	48.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male	oral: gavage	24.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male	oral: gavage	6.0000000000	h	no data	not applicable	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	42	Male/Female	oral: gavage	51.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	42	Male/Female	oral: gavage	27.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CD-1	42	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is identical to the substance	Myclobutanil		88671-89-0	2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile	Myclobutanil	C15H17ClN4	Clc1ccc(cc1)C(CCCC)(Cn2cncn2)C#N	InChI=1S/C15H17ClN4/c1-2-3-8-15(9-17,10-20-12-18-11-19-20)13-4-6-14(16)7-5-13/h4-7,11-12H,2-3,8,10H2,1H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)		25	Male	oral: gavage			yes	not applicable	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Tetraconazole	407-760-6	112281-77-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Tetraconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Tetraconazole	16Oct2008	2008	doi:10.2903/j.efsa.2008.152r
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Difenoconazole	601-613-1	119446-68-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Sweden	Difenoconazole	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance difenoconazole	07Jan2011	2011	doi:10.2903/j.efsa.2011.1967
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Bitertanol	259-513-5	55179-31-2	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Bitertanol	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance bitertanol	25Oct2010	2010	doi:10.2903/j.efsa.2010.1850
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Ambiguous			RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Myclobutanil		88671-89-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid			3-(4-chlorophenyl)-3-cyano-4-(1H-1,2,4-triazol-1-yl)butanoic acid	Not in list	C13H11ClN4O2	Clc1ccc(cc1)C(CC(=O)O)(Cn2cncn2)C#N	InChI=1S/C13H11ClN4O2/c14-11-3-1-10(2-4-11)13(6-15,5-12(19)20)7-18-9-16-8-17-18/h1-4,8-9H,5,7H2,(H,19,20)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	48.0000000000	h	yes, historical	not applicable	Negative		no evidence	RMS: Belgium	Myclobutanil (Revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance myclobutanil1	29Oct2010	2010	doi:10.2903/j.efsa.2010.1682
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Ambiguous	small colonies		RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Ambiguous	large colonies		RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Ambiguous	large colonies		RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Ambiguous	small colonies		RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent no treatment	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent no treatment	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	5.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)oxalamide			N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)ethanediamide	Not in list	C14H16N4O2	O=C(N(Cn1cccn1)c2c(C)cccc2C)C(N)=O	InChI=1S/C14H16N4O2/c1-10-5-3-6-11(2)12(10)18(14(20)13(15)19)9-17-8-4-7-16-17/h3-8H,9H2,1-2H3,(H2,15,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonic acid			2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonic acid	Not in list	C14H17N3O4S	O=C(CS(=O)(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21/h3-8H,9-10H2,1-2H3,(H,19,20,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	sodium N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfonate			sodium 2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethanesulfonate	Not in list	C14H16N3NaO4S	O=C(CS(=O)(=O)O[Na])N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H17N3O4S.Na/c1-11-5-3-6-12(2)14(11)17(10-16-8-4-7-15-16)13(18)9-22(19,20)21;/h3-8H,9-10H2,1-2H3,(H,19,20,21);/q;+1/p-1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is identical to the substance	Metazachlor	266-583-0	67129-08-2	2-chloro-N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Metazachlor	C14H16ClN3O	O=C(CCl)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C14H16ClN3O/c1-11-5-3-6-12(2)14(11)18(13(19)9-15)10-17-8-4-7-16-17/h3-8H,9-10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl acetic acid			({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)acetic acid	Not in list	C16H19N3O4S	O=C(CS(=O)CC(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C16H19N3O4S/c1-12-5-3-6-13(2)16(12)19(11-18-8-4-7-17-18)14(20)9-24(23)10-15(21)22/h3-8H,9-11H2,1-2H3,(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent no treatment	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent no treatment	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	methyl N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfoxide			N-(2,6-dimethylphenyl)-2-(methylsulfinyl)-N-(1H-pyrazol-1-ylmethyl)acetamide	Not in list	C15H19N3O2S	O=C(CS(C)=O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C15H19N3O2S/c1-12-6-4-7-13(2)15(12)18(14(19)10-21(3)20)11-17-9-5-8-16-17/h4-9H,10-11H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	N-[(2-hydroxycarbonyl-6-methyl)phenyl]-N-(1H-pyrazol-1-ylmethyl)oxalamide			2-[(carboxycarbonyl)(1H-pyrazol-1-ylmethyl)amino]-3-methylbenzoic acid	Not in list	C14H13N3O5	O=C(N(Cn1cccn1)c2c(C)cccc2C(=O)O)C(=O)O	InChI=1S/C14H13N3O5/c1-9-4-2-5-10(13(19)20)11(9)17(12(18)14(21)22)8-16-7-3-6-15-16/h2-7H,8H2,1H3,(H,19,20)(H,21,22)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Metazachlor	266-583-0	67129-08-2	single chemical entity	Component is a metabolite of the substance	3-[N-(2,6-dimethylphenyl)-N-(1H-pyrazol-1-ylmethyl)aminocarbonylmethylsulfinyl]-2-hydroxypropanoic acid			3-({2-[(2,6-dimethylphenyl)(1H-pyrazol-1-ylmethyl)amino]-2-oxoethyl}sulfinyl)-2-hydroxypropanoic acid	Not in list	C17H21N3O5S	O=C(CS(=O)CC(O)C(=O)O)N(Cn1cccn1)c2c(C)cccc2C	InChI=1S/C17H21N3O5S/c1-12-5-3-6-13(2)16(12)20(11-19-8-4-7-18-19)15(22)10-26(25)9-14(21)17(23)24/h3-8,14,21H,9-11H2,1-2H3,(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Metazachlor (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metazachlor	29Jul2008	2008	doi:10.2903/j.efsa.2008.145r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Penconazole	266-275-6	66246-88-6	single chemical entity	Component is identical to the substance	Penconazole	266-275-6	66246-88-6	1-[2-(2,4-dichlorophenyl)pentyl]-1H-1,2,4-triazole	Penconazole	C13H15Cl2N3	ClC2=C(C=CC(Cl)=C2)C(CCC)CN1N=CN=C1	InChI=1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Penconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance penconazole	30Oct2008	2008	doi:10.2903/j.efsa.2008.175r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	3	Male	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	3	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	6	Male	oral: gavage	13.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	6	Male	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Metconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Belgium	Metconazole (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Metconazole		125116-23-6	single chemical entity	Component is identical to the substance	Metconazole		125116-23-6	5-[(4-Chlorophenyl)methyl]-2,2-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	Metconazole (sum of isomers)	C17H22ClN3O	CC1(CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl)C	InChI=1S/C17H22ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,11-12,14,22H,7-10H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Belgium	Metconazole (Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance metconazole.	22Feb2006	2006	doi:10.2903/j.efsa.2006.64r
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Ambiguous			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Ambiguous			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Alpk:APf SD Rat	5	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Alpk:APf SD Rat	5	Male	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Alpk:APf SD Rat	5	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	10	Male	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	4-methylsulfonyl-2-nitro benzoic acid			4-(methylsulfonyl)-2-nitrobenzoic acid	Not in list	C8H7NO6S	O=S(C)(=O)c1cc(c(cc1)C(=O)O)N(=O)=O	InChI=1S/C8H7NO6S/c1-16(14,15)5-2-3-6(8(10)11)7(4-5)9(12)13/h2-4H,1H3,(H,10,11)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	10	Male	oral: gavage	28.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is a metabolite of the substance	2-amino-4-methylsulfonyl benzoic acid			2-amino-4-(methylsulfonyl)benzoic acid	Not in list	C8H9NO4S	O=S(C)(=O)c1cc(N)c(cc1)C(=O)O	InChI=1S/C8H9NO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,9H2,1H3,(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Positive			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA92			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA92			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Ambiguous			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Ambiguous			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Ambiguous			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent no treatment	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent no treatment	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent no treatment	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent no treatment	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported	3	Male	oral: gavage			no data	not applicable	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	with	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No data	Acceptable	Human (as organism)	Hep G2 human cell line			Not reported			no data	no data	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	without	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	Hep G2 human cell line			Not reported			yes	no data	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	without	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is identical to the substance	Metam-sodium	205-293-0	137-42-8	Sodium;N-methylcarbamodithioate	Not in list	C2H4NNaS2	CNC(=S)[S-].[Na+]	InChI=1S/C2H5NS2.Na/c1-3-2(4)5;/h1H3,(H2,3,4,5);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isothiocyanate	209-132-5	556-61-6	Methylimino(sulfanylidene)methane	Methyl-Isothiocyanate	C2H3NS	CN=C=S	InChI=1S/C2H3NS/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)				Not reported			no data	with	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	Rat (as animal)	Wistar		Male	inhalation: unspecified	8.0000000000	min	no data	not applicable	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	House mouse (as animal)				Not reported			no	no data	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1		Male	inhalation: unspecified	2.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	inhalation: aerosol			yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	B6C3F1		Male	inhalation: unspecified	2.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	House mouse (as animal)	lymphocytes			Not reported			no	no data	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	B6C3F1		Male/Female	inhalation: unspecified	4.0000000000	D	yes	not applicable	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	B6C3F1		Male	inhalation: unspecified	2.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed			yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	B6C3F1		Male/Female	inhalation: unspecified	4.0000000000	D	yes	not applicable	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	other			yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	B6C3F1		Male/Female	inhalation: unspecified	4.0000000000	D	yes	not applicable	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Metam-sodium	205-293-0	137-42-8	single chemical entity	Component is a metabolite of the substance	Methyl isocyanate	210-866-3	624-83-9	methylimino(oxo)methane	Not in list	C2H3NO	CN=C=O	InChI=1S/C2H3NO/c1-3-2-4/h1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Belgium	Metam-sodium (Updated DAR Re-submission)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metam	12Sep2011	2011	doi:10.2903/j.efsa.2011.2334
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	ICR	6	Male	oral: gavage	27.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Positive			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	fibroblast			Not reported			no data	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	fibroblast			Not reported			no data	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	with	Positive			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	5	Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alderly Park Rat	5	Male	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is identical to the substance	Napropamide	239-333-3	15299-99-7	N,N-diethyl-2-(1-naphthyloxy)propanamide	Napropamide	C17H21NO2	CCN(CC)C(=O)C(C)Oc2cccc1ccccc12	InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alderly Park Rat	5	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Napropamide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-(naphthalen-1-yloxy)propanoic acid			2-naphthalen-1-yloxypropanoic acid	Not in list	C13H12O3	CC(C(=O)O)OC1=CC=CC2=CC=CC=C21	InChI=1S/C13H12O3/c1-9(13(14)15)16-12-8-4-6-10-5-2-3-7-11(10)12/h2-9H,1H3,(H,14,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Denmark	Napropamide (Addendum 2)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	Phthalic acid	201-873-2	88-99-3	phthalic acid	Not in list	C8H6O4	C1=CC=C(C(=C1)C(=O)O)C(=O)O	InChI=1S/C8H6O4/c9-7(10)5-3-1-2-4-6(5)8(11)12/h1-4H,(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No data	Acceptable	House mouse (as animal)	Swiss	20	Male	intraperitoneal	5.0000000000	D	yes, concurrent vehicle	not applicable	Positive			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	mouse spot test	in vivo	According to	OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test)	No	Acceptable	House mouse (as animal)	C57BL		Male/Female	intraperitoneal			yes	not applicable	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	No data	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	6.0000000000	h	yes	not applicable	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	No data	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	26.0000000000	h	yes	not applicable	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)		10	Male	oral: feed	10.0000000000	D	yes	not applicable	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)		10	Male	oral: feed	10.0000000000	D	yes	not applicable	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	no data	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			complex product: derived from botanical sources	Component is identical to the substance	Orange oil				Not in list				organic	no structure			DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	no data	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	d-limonene	227-813-5	5989-27-5	(4R)-1-methyl-4-(1-methylethenyl)cyclohexene	Not in list	C10H16	CC(=C)[C@@H]1CCC(=CC1)C	InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,10H,1,5-7H2,2-3H3/t10-/m0/s1	organic	compound	DSSTox	DSSTox	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			no data	no data	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	Linalool	201-134-4	78-70-6	3,7-dimethylocta-1,6-dien-3-ol	linalool	C10H18O	CC(=CCCC(C)(C=C)O)C	InChI=1S/C10H18O/c1-5-10(4,11)8-6-7-9(2)3/h5,7,11H,1,6,8H2,2-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	no data	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	β-myrcene	204-622-5	123-35-3	7-methyl-3-methylideneocta-1,6-diene	myrcene	C10H16	CC(=CCCC(=C)C=C)C	InChI=1S/C10H16/c1-5-10(4)8-6-7-9(2)3/h5,7H,1,4,6,8H2,2-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	no data	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	β-myrcene	204-622-5	123-35-3	7-methyl-3-methylideneocta-1,6-diene	myrcene	C10H16	CC(=CCCC(=C)C=C)C	InChI=1S/C10H16/c1-5-10(4)8-6-7-9(2)3/h5,7H,1,4,6,8H2,2-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	β-myrcene	204-622-5	123-35-3	7-methyl-3-methylideneocta-1,6-diene	myrcene	C10H16	CC(=CCCC(=C)C=C)C	InChI=1S/C10H16/c1-5-10(4)8-6-7-9(2)3/h5,7H,1,4,6,8H2,2-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	β-myrcene	204-622-5	123-35-3	7-methyl-3-methylideneocta-1,6-diene	myrcene	C10H16	CC(=CCCC(=C)C=C)C	InChI=1S/C10H16/c1-5-10(4)8-6-7-9(2)3/h5,7H,1,4,6,8H2,2-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar	8	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Orange oil			single chemical entity	Component is part of a group assessment	β-myrcene	204-622-5	123-35-3	7-methyl-3-methylideneocta-1,6-diene	myrcene	C10H16	CC(=CCCC(=C)C=C)C	InChI=1S/C10H16/c1-5-10(4)8-6-7-9(2)3/h5,7H,1,4,6,8H2,2-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Wistar	8	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Orange oil	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orange oil	11Feb2013	2013	doi:10.2903/j.efsa.2013.3090
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1		No data	intraperitoneal	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Rat (as animal)	Sprague-Dawley	6	Male/Female	oral: unspecified	28.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Not reported	5	Male	oral: unspecified	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1		No data	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Positive		direct evidence-cytotoxicity	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Positive		no evidence	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	no information		RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			yes	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss		Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	CD-1		No data	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Not reported	5	Male	oral: unspecified	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	embryo cells			Not reported			yes	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	2-hydroxynaphthalene-1,4-dione	201-496-3	83-72-7	4-hydroxynaphthalene-1,2-dione	Not in list	C10H6O3	C1=CC=C2C(=C1)C(=CC(=O)C2=O)O	InChI=1S/C10H6O3/c11-8-5-9(12)10(13)7-4-2-1-3-6(7)8/h1-5,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)				Not reported			no data	no data	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	no data	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	Equivalent or similar to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Schizosaccharomyces pombe (as organism)				Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Schizosaccharomyces pombe (as organism)				Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	fibroblast			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	fibroblast			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		Male	oral: gavage			no data	not applicable	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		No data	oral: gavage			no data	not applicable	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss	18	Male	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss	18	Male	oral: gavage	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)		4	No data	oral: unspecified	3.0000000000	D	yes	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Hamster (as animal)	Chinese	12	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Balb/c		Male	oral: gavage	32.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Balb/c		Male	oral: gavage	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Balb/c		Male	oral: gavage	18.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		Male	Not reported			no data	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	Hamster (as animal)	Chinese		No data	Not reported			no data	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Balb/c		No data	oral: gavage	18.0000000000	h	yes	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Balb/c		No data	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Balb/c		No data	oral: gavage	30.0000000000	h	yes	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Sprague-Dawley	2	Male	oral: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	20	Male	oral: unspecified			yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported		Male	Not reported			no data	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	Balb/c		Male	oral: gavage			yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	House mouse (as animal)	NMRI	15	Male	oral: gavage	5.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported	15	Male	oral: unspecified	3.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	oral: unspecified	30.0000000000	D	no data	not applicable	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	oral: unspecified	24.0000000000	h	no data	not applicable	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)-3-methylurea			1-methyl-3-(4-propan-2-ylphenyl)urea	Not in list	C11H16N2O	O=C(Nc1ccc(cc1)C(C)C)NC	InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)-3-methylurea			1-methyl-3-(4-propan-2-ylphenyl)urea	Not in list	C11H16N2O	O=C(Nc1ccc(cc1)C(C)C)NC	InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)-3-methylurea			1-methyl-3-(4-propan-2-ylphenyl)urea	Not in list	C11H16N2O	O=C(Nc1ccc(cc1)C(C)C)NC	InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)-3-methylurea			1-methyl-3-(4-propan-2-ylphenyl)urea	Not in list	C11H16N2O	O=C(Nc1ccc(cc1)C(C)C)NC	InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)-3-methylurea			1-methyl-3-(4-propan-2-ylphenyl)urea	Not in list	C11H16N2O	O=C(Nc1ccc(cc1)C(C)C)NC	InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)-3-methylurea			1-methyl-3-(4-propan-2-ylphenyl)urea	Not in list	C11H16N2O	O=C(Nc1ccc(cc1)C(C)C)NC	InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)-3-methylurea			1-methyl-3-(4-propan-2-ylphenyl)urea	Not in list	C11H16N2O	O=C(Nc1ccc(cc1)C(C)C)NC	InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)-3-methylurea			1-methyl-3-(4-propan-2-ylphenyl)urea	Not in list	C11H16N2O	O=C(Nc1ccc(cc1)C(C)C)NC	InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	CM891			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)-3-methylurea			1-methyl-3-(4-propan-2-ylphenyl)urea	Not in list	C11H16N2O	O=C(Nc1ccc(cc1)C(C)C)NC	InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)-3-methylurea			1-methyl-3-(4-propan-2-ylphenyl)urea	Not in list	C11H16N2O	O=C(Nc1ccc(cc1)C(C)C)NC	InChI=1S/C11H16N2O/c1-8(2)9-4-6-10(7-5-9)13-11(14)12-3/h4-8H,1-3H3,(H2,12,13,14)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Positive			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Not reported	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Not reported	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Not reported	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: unspecified	12.0000000000	h	no data	not applicable	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	40	Male/Female	oral: unspecified	6.0000000000	h	no data	not applicable	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	6	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Inconclusive			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Inconclusive	no information		RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	Chinese	48	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	Chinese	48	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	4-methoxy-6-methyl-1,3,5-triazine-2-amine	216-790-7	1668-54-8	4-methoxy-6-methyl-1,3,5-triazin-2-amine	Not in list	C5H8N4O	CC1=NC(=NC(=N1)OC)N	InChI=1S/C5H8N4O/c1-3-7-4(6)9-5(8-3)10-2/h1-2H3,(H2,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	Chinese	48	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-(carbamoylsulfamoyl)benzoate			methyl 2-(carbamoylsulfamoyl)benzoate	Not in list	C9H10N2O5S	O=S(=O)(NC(N)=O)c1ccccc1C(=O)OC	InChI=1S/C9H10N2O5S/c1-16-8(12)6-4-2-3-5-7(6)17(14,15)11-9(10)13/h2-5H,1H3,(H3,10,11,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoylbenzoate			methyl 2-sulfamoylbenzoate	Not in list	C8H9NO4S	COC(=O)C1=CC=CC=C1S(=O)(=O)N	InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoylbenzoate			methyl 2-sulfamoylbenzoate	Not in list	C8H9NO4S	COC(=O)C1=CC=CC=C1S(=O)(=O)N	InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoylbenzoate			methyl 2-sulfamoylbenzoate	Not in list	C8H9NO4S	COC(=O)C1=CC=CC=C1S(=O)(=O)N	InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoylbenzoate			methyl 2-sulfamoylbenzoate	Not in list	C8H9NO4S	COC(=O)C1=CC=CC=C1S(=O)(=O)N	InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoylbenzoate			methyl 2-sulfamoylbenzoate	Not in list	C8H9NO4S	COC(=O)C1=CC=CC=C1S(=O)(=O)N	InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoylbenzoate			methyl 2-sulfamoylbenzoate	Not in list	C8H9NO4S	COC(=O)C1=CC=CC=C1S(=O)(=O)N	InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoylbenzoate			methyl 2-sulfamoylbenzoate	Not in list	C8H9NO4S	COC(=O)C1=CC=CC=C1S(=O)(=O)N	InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoylbenzoate			methyl 2-sulfamoylbenzoate	Not in list	C8H9NO4S	COC(=O)C1=CC=CC=C1S(=O)(=O)N	InChI=1S/C8H9NO4S/c1-13-8(10)6-4-2-3-5-7(6)14(9,11)12/h2-5H,1H3,(H2,9,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	4	Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is identical to the substance	Nicosulfuron		111991-09-4	2-[(4,6-Dimethoxypyrimidin-2-yl)carbamoylsulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Nicosulfuron	C15H18N6O6S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C15H18N6O6S/c1-21(2)13(22)9-6-5-7-16-12(9)28(24,25)20-15(23)19-14-17-10(26-3)8-11(18-14)27-4/h5-8H,1-4H3,(H2,17,18,19,20,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	4	Male	oral: gavage	16.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	72.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide			N,N-dimethyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C8H11N3O3S	CN(C)C(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C8H11N3O3S/c1-11(2)8(12)6-4-3-5-10-7(6)15(9,13)14/h3-5H,1-2H3,(H2,9,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-Amino-4,6-dimethoxypyrimidine	252-969-6	36315-01-2	4,6-Dimethoxypyrimidin-2-amine	Not in list	C6H9N3O2	COC1=CC(=NC(=N1)N)OC	InChI=1S/C6H9N3O2/c1-10-4-3-5(11-2)9-6(7)8-4/h3H,1-2H3,(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamimidoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamimidoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H14N6O4S	O=S(=O)(NC(=O)NC(=N)N)c1ncccc1C(=O)N(C)C	InChI=1S/C10H14N6O4S/c1-16(2)8(17)6-4-3-5-13-7(6)21(19,20)15-10(18)14-9(11)12/h3-5H,1-2H3,(H5,11,12,14,15,18)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	small colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	large colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-[(Carbamoylcarbamoyl)sulfamoyl]-N,Ndimethylpyridine-3-carboxamide			2-[(carbamoylcarbamoyl)sulfamoyl]-N,N-dimethylpyridine-3-carboxamide	Not in list	C10H13N5O5S	O=S(=O)(NC(=O)NC(N)=O)c1ncccc1C(=O)N(C)C	InChI=1S/C10H13N5O5S/c1-15(2)8(16)6-4-3-5-12-7(6)21(19,20)14-10(18)13-9(11)17/h3-5H,1-2H3,(H4,11,13,14,17,18)	metal	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	large colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	small colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	N-methyl-2-sulfamoylpyridine-3-carboxamide			N-methyl-2-sulfamoylpyridine-3-carboxamide	Not in list	C7H9N3O3S	CNC(=O)C1=C(N=CC=C1)S(=O)(=O)N	InChI=1S/C7H9N3O3S/c1-9-6(11)5-3-2-4-10-7(5)14(8,12)13/h2-4H,1H3,(H,9,11)(H2,8,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	mixture or formulation	Component is part of a group assessment	Nicosulfuron leachate (lysimeter product)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	mixture or formulation	Component is part of a group assessment	Nicosulfuron leachate (lysimeter product)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	mixture or formulation	Component is part of a group assessment	Nicosulfuron leachate (lysimeter product)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	mixture or formulation	Component is part of a group assessment	Nicosulfuron leachate (lysimeter product)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	mixture or formulation	Component is part of a group assessment	Nicosulfuron leachate (lysimeter product)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	mixture or formulation	Component is part of a group assessment	Nicosulfuron leachate (lysimeter product)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	mixture or formulation	Component is part of a group assessment	Nicosulfuron leachate (lysimeter product)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	mixture or formulation	Component is part of a group assessment	Nicosulfuron leachate (lysimeter product)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Nicosulfuron	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Nicosulfuron		111991-09-4	single chemical entity	Component is a metabolite of the substance	2-{[(4-Hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,Ndimethylpyridine-3-carboxamide			2-{[(4-hydroxy-6-methoxypyrimidin-2-yl)carbamoyl]sulfamoyl}-N,N-dimethylpyridine-3-carboxamide	Not in list	C14H16N6O6S	O=S(=O)(NC(=O)Nc1nc(O)cc(OC)n1)c2ncccc2C(=O)N(C)C	InChI=1S/C14H16N6O6S/c1-20(2)12(22)8-5-4-6-15-11(8)27(24,25)19-14(23)18-13-16-9(21)7-10(17-13)26-3/h4-7H,1-3H3,(H3,16,17,18,19,21,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Nicosulfuron (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance nicosulfuron	29Jan2008	2008	doi:10.2903/j.efsa.2008.120r
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Ambiguous			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2-[((RS)-1-Carboxy-ethyl)-(2-methoxy-acetyl)-amino]-3-methyl-benzoic acid			2-[(1-carboxyethyl)(methoxyacetyl)amino]-3-methylbenzoic acid	Not in list	C14H17NO6	CC(N(C(=O)COC)c1c(C)cccc1C(=O)O)C(=O)O	InChI=1S/C14H17NO6/c1-8-5-4-6-10(14(19)20)12(8)15(9(2)13(17)18)11(16)7-21-3/h4-6,9H,7H2,1-3H3,(H,17,18)(H,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(RS)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	CC(N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	large colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	small colonies		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	N-(2,6-Dimethyl-phenyl)-2-methoxy-acetamide			N-(2,6-dimethylphenyl)-2-methoxyacetamide	Not in list	C11H15NO2	O=C(Nc1c(C)cccc1C)COC	InChI=1S/C11H15NO2/c1-8-5-4-6-9(2)11(8)12-10(13)7-14-3/h4-6H,7H2,1-3H3,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	Rat (as animal)	Not reported		No data	intraperitoneal			no data	not applicable	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	Drosophila SLRL test	in vivo	Equivalent or similar to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No data	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	Not reported	3.0000000000	D	no data	not applicable	Negative			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Imazalil	252-615-0	35554-44-0	single chemical entity	Component is identical to the substance	Imazalil	252-615-0	35554-44-0	1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxyethyl]imidazole	Imazalil	C14H14Cl2N2O	C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl	InChI=1S/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	no data	Positive			RMS: The Netherlands - CoRMS: Spain	Imazalil	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance imazalil	19Mar2010	2010	doi:10.2903/j.efsa.2010.1526
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-hydroxy-terbuthylazine			4-amino-6-(tert-butylamino)-1,3,5-triazin-2-ol	Desethyl-hydroxy-terbuthylazine	C7H13N5O	Nc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H13N5O/c1-7(2,3)12-5-9-4(8)10-6(13)11-5/h1-3H3,(H4,8,9,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Hydroxy-terbuthylazine			4-(tert-butylamino)-6-(ethylamino)-1,3,5-triazin-2-ol	Not in list	C9H17N5O	Oc1nc(NCC)nc(NC(C)(C)C)n1	InChI=1S/C9H17N5O/c1-5-10-6-11-7(13-8(15)12-6)14-9(2,3)4/h5H2,1-4H3,(H3,10,11,12,13,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)		Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2-Chloro-4,6-diamino-s-triazin	222-260-6	3397-62-4	6-Chloro-1,3,5-triazine-2,4-diamine	Atrazine, Desethyl-Desisopropyl-	C3H4ClN5	C1(=NC(=NC(=N1)Cl)N)N	InChI=1S/C3H4ClN5/c4-1-7-2(5)9-3(6)8-1/h(H4,5,6,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	16	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is identical to the substance	Terbuthylazine	227-637-9	5915-41-3	N-tert-butyl-6-chloro-N'-ethyl-1,3,5-triazine-2,4-diamine	Terbuthylazine	C9H16ClN5	CCNc1nc(Cl)nc(NC(C)(C)C)n1	InChI=1/C9H16ClN5/c1-5-11-7-12-6(10)13-8(14-7)15-9(2,3)4/h5H2,1-4H3,(H2,11,12,13,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	small colonies		RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	small colonies		RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	large colonies		RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	large colonies		RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	10	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	10	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	6	Male	Not reported	2.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	Desethyl-terbuthylazine		30125-63-4	2-N-tert-butyl-6-chloro-1,3,5-triazine-2,4-diamine	Terbuthylazine, Desethyl-	C7H12ClN5	CC(C)(C)NC1=NC(=NC(=N1)N)Cl	InChI=1S/C7H12ClN5/c1-7(2,3)13-6-11-4(8)10-5(9)12-6/h1-3H3,(H3,9,10,11,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Alpk:APf SD Rat	6	Male	Not reported	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one			2,6-dihydroxy-7,7-dimethyl-7,8-dihydroimidazo[1,2-a][1,3,5]triazin-4(6H)-one	Not in list	C7H10N4O3	O=C1N=C(O)N=C2NC(C)(C)C(O)N12	InChI=1S/C7H10N4O3/c1-7(2)3(12)11-4(10-7)8-5(13)9-6(11)14/h3,12H,1-2H3,(H2,8,9,10,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	6-(tert-butylamino)-1,3,5-triazine-2,4-diol			6-(tert-butylamino)-1,3,5-triazine-2,4-diol	Not in list	C7H12N4O2	Oc1nc(NC(C)(C)C)nc(O)n1	InChI=1S/C7H12N4O2/c1-7(2,3)11-4-8-5(12)10-6(13)9-4/h1-3H3,(H3,8,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	large colonies		RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	small colonies		RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Terbuthylazine	227-637-9	5915-41-3	single chemical entity	Component is a metabolite of the substance	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one			4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	4-(Tert-butylamino)-6-hydroxy-1-methyl-1,3,5-triazin-2(1H)-one	C8H14N4O2	O=C1N=C(NC(C)(C)C)N=C(O)N1C	InChI=1S/C8H14N4O2/c1-8(2,3)11-5-9-6(13)12(4)7(14)10-5/h1-4H3,(H2,9,10,11,13,14)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Terbuthylazine (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance terbuthylazine	10Jan2011	2011	doi:10.2903/j.efsa.2011.1969
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	no data	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	no data	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	no data	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Lenacil	218-499-0	2164-08-1	single chemical entity	Component is identical to the substance	Lenacil	218-499-0	2164-08-1	3-cyclohexyl-6,7-dihydro-1H-cyclopenta[d]pyrimidine-2,4(3H,5H)-dione	Lenacil	C13H18N2O2	O=C1NC2=C(CCC2)C(=O)N1C3CCCCC3	InChI=1/C13H18N2O2/c16-12-10-7-4-8-11(10)14-13(17)15(12)9-5-2-1-3-6-9/h9H,1-8H2,(H,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	no data	Negative			RMS: Belgium	Lenacil	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance lenacil	07Oct2009	2009	doi:10.2903/j.efsa.2009.1326
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Salmonella typhimurium (as organism)				Not reported			no data	no data	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	without	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	with	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	No guideline followed	Not reported	Not applicable	Acceptable	Other				Not reported			no data	no data	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-[(dimethoxyphosphoryl)sulfanyl]butanedioate		1634-78-2	Diethyl 2-dimethoxyphosphorylsulfanylbutanedioate	Malaoxon	C10H19O7PS	CCOC(=O)CC(C(=O)OCC)SP(=O)(OC)OC	InChI=1S/C10H19O7PS/c1-5-16-9(11)7-8(10(12)17-6-2)19-18(13,14-3)15-4/h8H,5-7H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-[(dimethoxyphosphoryl)sulfanyl]butanedioate		1634-78-2	Diethyl 2-dimethoxyphosphorylsulfanylbutanedioate	Malaoxon	C10H19O7PS	CCOC(=O)CC(C(=O)OCC)SP(=O)(OC)OC	InChI=1S/C10H19O7PS/c1-5-16-9(11)7-8(10(12)17-6-2)19-18(13,14-3)15-4/h8H,5-7H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Swiss		Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Swiss		Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent no treatment	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Swiss		Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent no treatment	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal			no data	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	Not reported			Not reported			no data	no data	Negative			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is identical to the substance	Malathion	204-497-7	121-75-5	diethyl 2-[(dimethoxyphosphorothioyl)sulfanyl]succinate	Malathion	C10H19O6PS2	CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC	InChI=1/C10H19O6PS2/c1-5-15-9(11)7-8(10(12)16-6-2)19-17(18,13-3)14-4/h8H,5-7H2,1-4H3	organic	compound	Other	Other		other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)			No data	Not reported			no data	not applicable	Positive			RMS: Finland	Malathion (Addendum 1)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid		1190-29-0	2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid	Not in list	C8H15O6PS2	CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC	InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid		1190-29-0	2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid	Not in list	C8H15O6PS2	CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC	InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid		1190-29-0	2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid	Not in list	C8H15O6PS2	CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC	InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid		1190-29-0	2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid	Not in list	C8H15O6PS2	CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC	InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid		1190-29-0	2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid	Not in list	C8H15O6PS2	CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC	InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid		1190-29-0	2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid	Not in list	C8H15O6PS2	CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC	InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid		1190-29-0	2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid	Not in list	C8H15O6PS2	CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC	InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid		1190-29-0	2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid	Not in list	C8H15O6PS2	CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC	InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid		1190-29-0	2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid	Not in list	C8H15O6PS2	CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC	InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]-4-ethoxy-4-oxobutanoic acid		1190-29-0	2-Dimethoxyphosphinothioylsulfanyl-4-ethoxy-4-oxobutanoic acid	Not in list	C8H15O6PS2	CCOC(=O)CC(C(=O)O)SP(=S)(OC)OC	InChI=1S/C8H15O6PS2/c1-4-14-7(9)5-6(8(10)11)17-15(16,12-2)13-3/h6H,4-5H2,1-3H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid			2-dimethoxyphosphinothioylsulfanylbutanedioic acid	Not in list	C6H11O6PS2	COP(=S)(OC)SC(CC(=O)O)C(=O)O	InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid			2-dimethoxyphosphinothioylsulfanylbutanedioic acid	Not in list	C6H11O6PS2	COP(=S)(OC)SC(CC(=O)O)C(=O)O	InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid			2-dimethoxyphosphinothioylsulfanylbutanedioic acid	Not in list	C6H11O6PS2	COP(=S)(OC)SC(CC(=O)O)C(=O)O	InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid			2-dimethoxyphosphinothioylsulfanylbutanedioic acid	Not in list	C6H11O6PS2	COP(=S)(OC)SC(CC(=O)O)C(=O)O	InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid			2-dimethoxyphosphinothioylsulfanylbutanedioic acid	Not in list	C6H11O6PS2	COP(=S)(OC)SC(CC(=O)O)C(=O)O	InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid			2-dimethoxyphosphinothioylsulfanylbutanedioic acid	Not in list	C6H11O6PS2	COP(=S)(OC)SC(CC(=O)O)C(=O)O	InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid			2-dimethoxyphosphinothioylsulfanylbutanedioic acid	Not in list	C6H11O6PS2	COP(=S)(OC)SC(CC(=O)O)C(=O)O	InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid			2-dimethoxyphosphinothioylsulfanylbutanedioic acid	Not in list	C6H11O6PS2	COP(=S)(OC)SC(CC(=O)O)C(=O)O	InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid			2-dimethoxyphosphinothioylsulfanylbutanedioic acid	Not in list	C6H11O6PS2	COP(=S)(OC)SC(CC(=O)O)C(=O)O	InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	(2RS)- 2-[(dimethoxyphosphorothioyl)sulfanyl]butanedioic acid			2-dimethoxyphosphinothioylsulfanylbutanedioic acid	Not in list	C6H11O6PS2	COP(=S)(OC)SC(CC(=O)O)C(=O)O	InChI=1S/C6H11O6PS2/c1-11-13(14,12-2)15-4(6(9)10)3-5(7)8/h4H,3H2,1-2H3,(H,7,8)(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate			diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate	Not in list	C9H17O6PS2	CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC	InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate			diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate	Not in list	C9H17O6PS2	CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC	InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate			diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate	Not in list	C9H17O6PS2	CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC	InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate			diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate	Not in list	C9H17O6PS2	CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC	InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate			diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate	Not in list	C9H17O6PS2	CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC	InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate			diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate	Not in list	C9H17O6PS2	CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC	InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate			diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate	Not in list	C9H17O6PS2	CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC	InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate			diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate	Not in list	C9H17O6PS2	CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC	InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate			diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate	Not in list	C9H17O6PS2	CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC	InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Malathion	204-497-7	121-75-5	single chemical entity	Component is a metabolite of the substance	Diethyl (2RS)-2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate			diethyl 2-{[hydroxy(methoxy)phosphorothioyl]sulfanyl}butanedioate	Not in list	C9H17O6PS2	CCOC(=O)CC(SP(=S)(O)OC)C(=O)OCC	InChI=1S/C9H17O6PS2/c1-4-14-8(10)6-7(9(11)15-5-2)18-16(12,17)13-3/h7H,4-6H2,1-3H3,(H,12,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Malathion (Report and Proposed Decision of the United Kingdom made to the European Commission under Article 8 of 91/414/EEC Summary, Scientific Evaluation and Assessment)	2009	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance malathion	28Jul2009	2009	doi:10.2903/j.efsa.2009.333r
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Ambiguous			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Wistar		Male	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Positive	no information		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No data	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Positive	no information		RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Positive			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Positive			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No data	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	oral: unspecified			no data	not applicable	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No data	Acceptable	House mouse (as animal)	Not reported		No data	oral: unspecified			no data	not applicable	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Rat (as animal)	Not reported		No data	intraperitoneal			no data	not applicable	Positive			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Other			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	2,6-dimethylaniline	201-758-7	87-62-7	2,6-dimethylaniline	Not in list	C8H11N	CC1=C(C(=CC=C1)C)N	InChI=1S/C8H11N/c1-6-4-3-5-7(2)8(6)9/h3-5H,9H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methylurea			1-(4-bromophenyl)-3-methylurea	Not in list	C8H9BrN2O	Brc1ccc(NC(=O)NC)cc1	InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methylurea			1-(4-bromophenyl)-3-methylurea	Not in list	C8H9BrN2O	Brc1ccc(NC(=O)NC)cc1	InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methylurea			1-(4-bromophenyl)-3-methylurea	Not in list	C8H9BrN2O	Brc1ccc(NC(=O)NC)cc1	InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methylurea			1-(4-bromophenyl)-3-methylurea	Not in list	C8H9BrN2O	Brc1ccc(NC(=O)NC)cc1	InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methylurea			1-(4-bromophenyl)-3-methylurea	Not in list	C8H9BrN2O	Brc1ccc(NC(=O)NC)cc1	InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methylurea			1-(4-bromophenyl)-3-methylurea	Not in list	C8H9BrN2O	Brc1ccc(NC(=O)NC)cc1	InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methylurea			1-(4-bromophenyl)-3-methylurea	Not in list	C8H9BrN2O	Brc1ccc(NC(=O)NC)cc1	InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methylurea			1-(4-bromophenyl)-3-methylurea	Not in list	C8H9BrN2O	Brc1ccc(NC(=O)NC)cc1	InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methylurea			1-(4-bromophenyl)-3-methylurea	Not in list	C8H9BrN2O	Brc1ccc(NC(=O)NC)cc1	InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methylurea			1-(4-bromophenyl)-3-methylurea	Not in list	C8H9BrN2O	Brc1ccc(NC(=O)NC)cc1	InChI=1/C8H9BrN2O/c1-10-8(12)11-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)urea			1-(4-bromophenyl)urea	Not in list	C7H7BrN2O	Brc1ccc(NC(N)=O)cc1	InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)urea			1-(4-bromophenyl)urea	Not in list	C7H7BrN2O	Brc1ccc(NC(N)=O)cc1	InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)urea			1-(4-bromophenyl)urea	Not in list	C7H7BrN2O	Brc1ccc(NC(N)=O)cc1	InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)urea			1-(4-bromophenyl)urea	Not in list	C7H7BrN2O	Brc1ccc(NC(N)=O)cc1	InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)urea			1-(4-bromophenyl)urea	Not in list	C7H7BrN2O	Brc1ccc(NC(N)=O)cc1	InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)urea			1-(4-bromophenyl)urea	Not in list	C7H7BrN2O	Brc1ccc(NC(N)=O)cc1	InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)urea			1-(4-bromophenyl)urea	Not in list	C7H7BrN2O	Brc1ccc(NC(N)=O)cc1	InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)urea			1-(4-bromophenyl)urea	Not in list	C7H7BrN2O	Brc1ccc(NC(N)=O)cc1	InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)urea			1-(4-bromophenyl)urea	Not in list	C7H7BrN2O	Brc1ccc(NC(N)=O)cc1	InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)urea			1-(4-bromophenyl)urea	Not in list	C7H7BrN2O	Brc1ccc(NC(N)=O)cc1	InChI=1/C7H7BrN2O/c8-5-1-3-6(4-2-5)10-7(9)11/h1-4H,(H3,9,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methoxyurea			1-(4-bromophenyl)-3-methoxyurea	Not in list	C8H9BrN2O2	Brc1ccc(NC(=O)NOC)cc1	InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methoxyurea			1-(4-bromophenyl)-3-methoxyurea	Not in list	C8H9BrN2O2	Brc1ccc(NC(=O)NOC)cc1	InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methoxyurea			1-(4-bromophenyl)-3-methoxyurea	Not in list	C8H9BrN2O2	Brc1ccc(NC(=O)NOC)cc1	InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methoxyurea			1-(4-bromophenyl)-3-methoxyurea	Not in list	C8H9BrN2O2	Brc1ccc(NC(=O)NOC)cc1	InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methoxyurea			1-(4-bromophenyl)-3-methoxyurea	Not in list	C8H9BrN2O2	Brc1ccc(NC(=O)NOC)cc1	InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methoxyurea			1-(4-bromophenyl)-3-methoxyurea	Not in list	C8H9BrN2O2	Brc1ccc(NC(=O)NOC)cc1	InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methoxyurea			1-(4-bromophenyl)-3-methoxyurea	Not in list	C8H9BrN2O2	Brc1ccc(NC(=O)NOC)cc1	InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methoxyurea			1-(4-bromophenyl)-3-methoxyurea	Not in list	C8H9BrN2O2	Brc1ccc(NC(=O)NOC)cc1	InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methoxyurea			1-(4-bromophenyl)-3-methoxyurea	Not in list	C8H9BrN2O2	Brc1ccc(NC(=O)NOC)cc1	InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metobromuron	221-301-5	3060-89-7	single chemical entity	Component is a metabolite of the substance	1-(4-bromophenyl)-3-methoxyurea			1-(4-bromophenyl)-3-methoxyurea	Not in list	C8H9BrN2O2	Brc1ccc(NC(=O)NOC)cc1	InChI=1/C8H9BrN2O2/c1-13-11-8(12)10-7-4-2-6(9)3-5-7/h2-5H,1H3,(H2,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Metobromuron	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metobromuron.	04Feb2014	2014	doi:10.2903/j.efsa.2014.3541
Metsulfuron-methyl	616-063-8	74223-64-6	single chemical entity	Component is identical to the substance	Metsulfuron-methyl	616-063-8	74223-64-6	methyl 2-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoylsulfamoyl]benzoate	Metsulfuron-methyl	C14H15N5O6S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C14H15N5O6S/c1-8-15-12(18-14(16-8)25-3)17-13(21)19-26(22,23)10-7-5-4-6-9(10)11(20)24-2/h4-7H,1-3H3,(H2,15,16,17,18,19,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Slovenia - CoRMS: Sweden	Metsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metsulfuron-methyl	29Jan2015	2015	doi:10.2903/j.efsa.2015.3936
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	naphthalen-1-ol	201-969-4	90-15-3	naphthalen-1-ol	Naphthol, 1-	C10H8O	C1=CC=C2C(=C1)C=CC=C2O	InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	naphthalen-1-ol	201-969-4	90-15-3	naphthalen-1-ol	Naphthol, 1-	C10H8O	C1=CC=C2C(=C1)C=CC=C2O	InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	naphthalen-1-ol	201-969-4	90-15-3	naphthalen-1-ol	Naphthol, 1-	C10H8O	C1=CC=C2C(=C1)C=CC=C2O	InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	naphthalen-1-ol	201-969-4	90-15-3	naphthalen-1-ol	Naphthol, 1-	C10H8O	C1=CC=C2C(=C1)C=CC=C2O	InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	naphthalen-1-ol	201-969-4	90-15-3	naphthalen-1-ol	Naphthol, 1-	C10H8O	C1=CC=C2C(=C1)C=CC=C2O	InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	naphthalen-1-ol	201-969-4	90-15-3	naphthalen-1-ol	Naphthol, 1-	C10H8O	C1=CC=C2C(=C1)C=CC=C2O	InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	naphthalen-1-ol	201-969-4	90-15-3	naphthalen-1-ol	Naphthol, 1-	C10H8O	C1=CC=C2C(=C1)C=CC=C2O	InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	naphthalen-1-ol	201-969-4	90-15-3	naphthalen-1-ol	Naphthol, 1-	C10H8O	C1=CC=C2C(=C1)C=CC=C2O	InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	naphthalen-1-ol	201-969-4	90-15-3	naphthalen-1-ol	Naphthol, 1-	C10H8O	C1=CC=C2C(=C1)C=CC=C2O	InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Napropamide	239-333-3	15299-99-7	single chemical entity	Component is a metabolite of the substance	naphthalen-1-ol	201-969-4	90-15-3	naphthalen-1-ol	Naphthol, 1-	C10H8O	C1=CC=C2C(=C1)C=CC=C2O	InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Denmark	Napropamide (Addendum 1)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance napropamide	15Apr2010	2010	doi:10.2903/j.efsa.2010.1565
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is identical to the substance	Orthosulfamuron		213464-77-8	1-(4,6-dimethoxypyrimidin-2-yl)-3-[2-(dimethylcarbamoyl)phenylsulfamoyl]urea	Orthosulfamuron	C16H20N6O6S	CN(C)C(=O)C1=CC=CC=C1NS(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C16H20N6O6S/c1-22(2)14(23)10-7-5-6-8-11(10)20-29(25,26)21-16(24)19-15-17-12(27-3)9-13(18-15)28-4/h5-9,20H,1-4H3,(H2,17,18,19,21,24)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Orthosulfamuron		213464-77-8	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea			1-(4-hydroxy-6-methoxypyrimidin-2-yl)urea	Not in list	C6H8N4O3	O=C(N)Nc1nc(O)cc(OC)n1	InChI=1S/C6H8N4O3/c1-13-4-2-3(11)8-6(9-4)10-5(7)12/h2H,1H3,(H4,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Italy	Orthosulfamuron (Final Addendum to the DAR)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance orthosulfamuron	13Mar2014	2014	doi:10.2903/j.efsa.2014.3353
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Pyroxsulam		422556-08-9	single chemical entity	Component is identical to the substance	Pyroxsulam		422556-08-9	N-(5,7-dimethoxy-[1,2,4]triazolo[1,5-alpha]pyrimidin-2-yl)-2-methoxy-4-(trifluoromethyl)pyridine-3-sulfonamide	Pyroxsulam	C14H13F3N6O5S	COC1=CC(=NC2=NC(=NN12)NS(=O)(=O)C3=C(C=CN=C3OC)C(F)(F)F)OC	InChI=1S/C14H13F3N6O5S/c1-26-8-6-9(27-2)23-13(19-8)20-12(21-23)22-29(24,25)10-7(14(15,16)17)4-5-18-11(10)28-3/h4-6H,1-3H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No data	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Pyroxsulam	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance pyroxsulam.	30Apr2013	2013	doi:10.2903/j.efsa.2013.3182
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	Swiss	3	No data	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is identical to the substance	Isoproturon	251-835-4	34123-59-6	1,1-dimethyl-3-(4-propan-2-ylphenyl)urea	Isoproturon	C12H18N2O	CC(C)C1=CC=C(C=C1)NC(=O)N(C)C	InChI=1S/C12H18N2O/c1-9(2)10-5-7-11(8-6-10)13-12(15)14(3)4/h5-9H,1-4H3,(H,13,15)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-{4-[(2RS-1-hydroxypropan-2-yl]phenyl}-1,1-dimethylurea			3-[4-(1-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)CO)N(C)C	InChI=1S/C12H18N2O2/c1-9(8-15)10-4-6-11(7-5-10)13-12(16)14(2)3/h4-7,9,15H,8H2,1-3H3,(H,13,16)	organic	compound	Other	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	3-[4-(2-hydroxy-2-propanyl)phenyl]-1,1-dimethylurea			3-[4-(2-hydroxypropan-2-yl)phenyl]-1,1-dimethylurea	Not in list	C12H18N2O2	O=C(Nc1ccc(cc1)C(C)(C)O)N(C)C	InChI=1S/C12H18N2O2/c1-12(2,16)9-5-7-10(8-6-9)13-11(15)14(3)4/h5-8,16H,1-4H3,(H,13,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	1-(4-isopropylphenyl)urea			(4-propan-2-ylphenyl)urea	Not in list	C10H14N2O	O=C(N)Nc1ccc(cc1)C(C)C	InChI=1S/C10H14N2O/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)	organic	compound	Other	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Isoproturon	251-835-4	34123-59-6	single chemical entity	Component is a metabolite of the substance	(2RS)-2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid			2-{4-[(dimethylcarbamoyl)amino]phenyl}propanoic acid	Not in list	C12H16N2O3	O=C(Nc1ccc(cc1)C(C)C(=O)O)N(C)C	InChI=1S/C12H16N2O3/c1-8(11(15)16)9-4-6-10(7-5-9)13-12(17)14(2)3/h4-8H,1-3H3,(H,13,17)(H,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Czech Republic	Isoproturon (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance isoproturon	20Aug2015	2015	doi:10.2903/j.efsa.2015.4206
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			no data	without	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Mesotrione	600-533-4	104206-82-8	single chemical entity	Component is identical to the substance	Mesotrione	600-533-4	104206-82-8	2-(4-methylsulfonyl-2-nitrobenzoyl)cyclohexane-1,3-dione	Mesotrione	C14H13NO7S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)C2C(=O)CCCC2=O)[N+](=O)[O-]	InChI=1S/C14H13NO7S/c1-23(21,22)8-5-6-9(10(7-8)15(19)20)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			no data	with	Negative			RMS: The United Kingdom - CoRMS: Belgium	Mesotrione (ZA1296)	2015	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance mesotrione	07Mar2016	2016	doi:10.2903/j.efsa.2016.4419
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is identical to the substance	Metalaxyl-M	615-135-6	70630-17-0	methyl (2R)-2-(N-(2-methoxyacetyl)-2,6-dimethylanilino)propanoate	Metalaxyl-M	C15H21NO4	CC1=C(C(=CC=C1)C)N(C(C)C(=O)OC)C(=O)COC	InChI=1S/C15H21NO4/c1-10-7-6-8-11(2)14(10)16(13(17)9-19-4)12(3)15(18)20-5/h6-8,12H,9H2,1-5H3/t12-/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(R)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			(2R)-2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	C[C@@H](N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)/t11-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Metalaxyl-M	615-135-6	70630-17-0	single chemical entity	Component is a metabolite of the substance	(R)-2-[(2,6-Dimethyl-phenyl)-(2-methoxy-acetyl)-amino]-propionic acid			(2R)-2-[(2,6-dimethylphenyl)(methoxyacetyl)amino]propanoic acid	Not in list	C14H19NO4	C[C@@H](N(C(=O)COC)c1c(C)cccc1C)C(=O)O	InChI=1S/C14H19NO4/c1-9-6-5-7-10(2)13(9)15(11(3)14(17)18)12(16)8-19-4/h5-7,11H,8H2,1-4H3,(H,17,18)/t11-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium - CoRMS: Greece	Metalaxyl-M	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance metalaxyl-M	03Mar2015	2015	doi:10.2903/j.efsa.2015.3999
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Positive			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Positive			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: unspecified	14.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is identical to the substance	Ethephon	240-718-3	16672-87-0	(2-chloroethyl)phosphonic acid	Ethephon	C2H6ClO3P	ClCCP(O)(=O)O	InChI=1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: unspecified	4.0000000000	h	yes	not applicable	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
Ethephon	240-718-3	16672-87-0	single chemical entity	Component is a metabolite of the substance	2-hydroxyethylphosphonic acid	245-370-6	22987-21-9	2-hydroxyethylphosphonic acid	2-Hydroxyethylphosphonic acid	C2H7O4P	C(CP(=O)(O)O)O	InChI=1S/C2H7O4P/c3-1-2-7(4,5)6/h3H,1-2H2,(H2,4,5,6)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: The Netherlands	Ethephon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethephon	15Jan2009	2009	doi:10.2903/j.efsa.2009.174r
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
S-abscisic acid	244-319-5	21293-29-8	single chemical entity	Component is identical to the substance	S-abscisic acid	244-319-5	21293-29-8	(2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid	Not in list	C15H20O4	CC1=CC(=O)CC([C@]1(/C=C/C(=C\C(=O)O)/C)O)(C)C	InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-/t15-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The Netherlands	S-abscisic acid	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance S-abscisic acid.	29Aug2013	2013	doi:10.2903/j.efsa.2013.3341
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA1530			Not reported			no data	without	Positive			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1		Male/Female	oral: feed	5.0000000000	D	no data	not applicable	Negative		no evidence	RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA94			Not reported			no data	with	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA92			Not reported			no data	without	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA92			Not reported			no data	with	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Positive			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA94			Not reported			no data	without	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sodium hypochlorite	231-668-3	7681-52-9	single chemical entity	Component is identical to the substance	Sodium hypochlorite	231-668-3	7681-52-9	Sodium;hypochlorite	Not in list	ClNaO	[O-]Cl.[Na+]	InChI=1S/ClO.Na/c1-2;/q-1;+1	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			no data	no data	Negative			RMS: The Netherlands	Sodium hypochlorite	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium hypochlorite	02Jul2012	2012	doi:10.2903/j.efsa.2012.2796
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	with	Positive			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	without	Positive			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Positive	no information		RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	no information		RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	inhalation: unspecified	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	inhalation: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulfuryl fluoride	220-281-5	2699-79-8	single chemical entity	Component is identical to the substance	Sulfuryl fluoride	220-281-5	2699-79-8	Sulfuryl difluoride	Sulfuryl fluoride	F2O2S	O=S(=O)(F)F	InChI=1S/F2O2S/c1-5(2,3)4	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	inhalation: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Sulfuryl Fluoride	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfuryl fluoride	14Jan2010	2010	doi:10.2903/j.efsa.2010.1441
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Ambiguous			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL	10	Male	oral: gavage	72.0000000000	h	yes	not applicable	Positive		direct evidence-cytotoxicity	RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	C57BL	10	Male	oral: gavage	48.0000000000	h	yes	not applicable	Positive		no evidence	RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	Not reported	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is identical to the substance	Sulcotrione		99105-77-8	2-[2-chloro-4-(methylsulfonyl)benzoyl]cyclohexane-1,3-dione	Sulcotrione	C14H13ClO5S	O=C2CCCC(=O)C2C(=O)c1ccc(cc1Cl)S(C)(=O)=O	InChI=1S/C14H13ClO5S/c1-21(19,20)8-5-6-9(10(15)7-8)14(18)13-11(16)3-2-4-12(13)17/h5-7,13H,2-4H2,1H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	Not reported	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulcotrione		99105-77-8	single chemical entity	Component is a metabolite of the substance	2-Chloro-4-(methylsulfonyl)-benzoic acid	406-520-8	53250-83-2	2-Chloro-4-methylsulfonylbenzoic acid	Not in list	C8H7ClO4S	CS(=O)(=O)C1=CC(=C(C=C1)C(=O)O)Cl	InChI=1S/C8H7ClO4S/c1-14(12,13)5-2-3-6(8(10)11)7(9)4-5/h2-4H,1H3,(H,10,11)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: Germany	Sulcotrione	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance Sulcotrione	16Oct2008	2008	doi:10.2903/j.efsa.2008.150r
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	no data	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	no data	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	no data	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	no data	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	no data	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Positive			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, historical	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, historical	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is identical to the substance	Sulfosulfuron		141776-32-1	1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea	Sulfosulfuron	C16H18N6O7S2	CCS(=O)(=O)C1=C(N2C=CC=CC2=N1)S(=O)(=O)NC(=O)NC3=NC(=CC(=N3)OC)OC	InChI=1S/C16H18N6O7S2/c1-4-30(24,25)13-14(22-8-6-5-7-10(22)17-13)31(26,27)21-16(23)20-15-18-11(28-2)9-12(19-15)29-3/h5-9H,4H2,1-3H3,(H2,18,19,20,21,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, historical	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamimidoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H14N6O5S2	NC(=N)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H14N6O5S2/c1-2-23(19,20)8-9(17-6-4-3-5-7(17)14-8)24(21,22)16-11(18)15-10(12)13/h3-6H,2H2,1H3,(H5,12,13,15,16,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Sulfosulfuron		141776-32-1	single chemical entity	Component is a metabolite of the substance	N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide			N-(carbamoylcarbamoyl)-2-(ethylsulfonyl)imidazo[1,2-a]pyridine-3-sulfonamide	Not in list	C11H13N5O6S2	NC(=O)NC(=O)NS(=O)(=O)c1c(nc2ccccn12)S(=O)(=O)CC	InChI=1/C11H13N5O6S2/c1-2-23(19,20)8-9(16-6-4-3-5-7(16)13-8)24(21,22)15-11(18)14-10(12)17/h3-6H,2H2,1H3,(H4,12,14,15,17,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden - CoRMS: Ireland	Sulfosulfuron (Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfosulfuron	14Jul2014	2014	doi:10.2903/j.efsa.2014.3764
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebuconazole	403-640-2	107534-96-3	single chemical entity	Component is identical to the substance	Tebuconazole	403-640-2	107534-96-3	1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol	Tebuconazole	C16H22ClN3O	OC(C(C)(C)C)(CN2N=CN=C2)CCC1=CC=C(Cl)C=C1	InChI=1S/C16H22ClN3O/c1-15(2,3)16(21,10-20-12-18-11-19-20)9-8-13-4-6-14(17)7-5-13/h4-7,11-12,21H,8-10H2,1-3H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	50	Male	oral: gavage			yes	not applicable	Negative			RMS: Denmark	Tebuconazole	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebuconazole.	03Jan2014	2014	doi:10.2903/j.efsa.2014.3485
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Ambiguous			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	hepatocytes			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	hepatocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is identical to the substance	Tebufenpyrad		119168-77-3	N-(4-tert-butylbenzyl)-4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Tebufenpyrad	C18H24ClN3O	O=C(NCC2=CC=C(C(C)(C)C)C=C2)C1=C(Cl)C(CC)=NN1C	InChI=1S/C18H24ClN3O/c1-6-14-15(19)16(22(5)21-14)17(23)20-11-12-7-9-13(10-8-12)18(2,3)4/h7-10H,6,11H2,1-5H3,(H,20,23)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid			2-(4-{[(4-chloro-3-ethyl-1-methyl-1H-pyrazol-5-yl)carbonyl]amino}phenyl)-2-methylpropanoic acid	Not in list	C17H20ClN3O3	Clc2c(CC)nn(C)c2C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O	InChI=1/C17H20ClN3O3/c1-5-12-13(18)14(21(4)20-12)15(22)19-11-8-6-10(7-9-11)17(2,3)16(23)24/h6-9H,5H2,1-4H3,(H,19,22)(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide			4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Not in list	C7H10ClN3O	Clc1c(CC)nn(C)c1C(=O)N	InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide			4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Not in list	C7H10ClN3O	Clc1c(CC)nn(C)c1C(=O)N	InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide			4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Not in list	C7H10ClN3O	Clc1c(CC)nn(C)c1C(=O)N	InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide			4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Not in list	C7H10ClN3O	Clc1c(CC)nn(C)c1C(=O)N	InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide			4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Not in list	C7H10ClN3O	Clc1c(CC)nn(C)c1C(=O)N	InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide			4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Not in list	C7H10ClN3O	Clc1c(CC)nn(C)c1C(=O)N	InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide			4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Not in list	C7H10ClN3O	Clc1c(CC)nn(C)c1C(=O)N	InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide			4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Not in list	C7H10ClN3O	Clc1c(CC)nn(C)c1C(=O)N	InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide			4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Not in list	C7H10ClN3O	Clc1c(CC)nn(C)c1C(=O)N	InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Tebufenpyrad		119168-77-3	single chemical entity	Component is a metabolite of the substance	4-chloro-3-ethyl-1-methyl-5-pyrazolecarboxamide			4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide	Not in list	C7H10ClN3O	Clc1c(CC)nn(C)c1C(=O)N	InChI=1/C7H10ClN3O/c1-3-4-5(8)6(7(9)12)11(2)10-4/h3H2,1-2H3,(H2,9,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenpyrad	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tebufenpyrad	30Mar2009	2009	doi:10.2903/j.efsa.2009.192r
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Spain	Thiabendazole (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	House mouse (as animal)	CD-1	3	Male	oral: gavage	4.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	House mouse (as animal)	CD-1	3	Male	oral: gavage	14.0000000000	h	no data	not applicable	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CF-1	8	Male/Female	Not reported	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Fischer344	15	Male	oral: feed	56.0000000000	D	yes	not applicable	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	SOS/umu test	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	PQ37			Not reported			yes	no data	Positive			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	no data	Positive			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	embryo cells			Not reported			yes	without	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	embryo cells			Not reported			yes	with	Positive			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Ambiguous			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Positive			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	BDF1 mouse	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male/Female	intraperitoneal	12.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male/Female	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Positive			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	12	Male/Female	oral: gavage	42.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Thymol	201-944-8	89-83-8	single chemical entity	Component is identical to the substance	Thymol	201-944-8	89-83-8	5-Methyl-2-propan-2-ylphenol	Thymol	C10H14O	CC1=CC(=C(C=C1)C(C)C)O	InChI=1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	12	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Thymol	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thymol	05Nov2012	2012	doi:10.2903/j.efsa.2012.2916
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Tolclofos-methyl	260-515-3	57018-04-9	single chemical entity	Component is identical to the substance	Tolclofos-methyl	260-515-3	57018-04-9	O-(2,6-dichloro-4-methylphenyl) O,O-dimethyl thiophosphate	Tolclofos-methyl	C9H11Cl2O3PS	S=P(OC)(OC)OC1=C(Cl)C=C(C)C=C1Cl	InChI=1S/C9H11Cl2O3PS/c1-6-4-7(10)9(8(11)5-6)14-15(16,12-2)13-3/h4-5H,1-3H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	intraperitoneal	7.0000000000	week	yes, historical	not applicable	Negative			RMS: Sweden	Tolclofos-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolclofos-methyl	18Aug2005	2005	doi:10.2903/j.efsa.2005.32ar
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Positive			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Positive			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Positive			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is identical to the substance	Topramezone	606-699-4	210631-68-8	4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one	Topramezone (BAS 670H)	C16H17N3O5S	CC1=C(C=CC(=C1C2=NOCC2)S(=O)(=O)C)C(=O)C3=CNN(C3=O)C	InChI=1S/C16H17N3O5S/c1-9-10(15(20)11-8-17-19(2)16(11)21)4-5-13(25(3,22)23)14(9)12-6-7-24-18-12/h4-5,8,17H,6-7H2,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Topramezone	606-699-4	210631-68-8	single chemical entity	Component is a metabolite of the substance	3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid			3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)benzoic acid	Not in list	C12H13NO5S	CS(=O)(=O)c2ccc(c(C)c2C=1CCON=1)C(O)=O	InChI=1/C12H13NO5S/c1-7-8(12(14)15)3-4-10(19(2,16)17)11(7)9-5-6-18-13-9/h3-4H,5-6H2,1-2H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Topramezone (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance topramezone	03Feb2014	2014	doi:10.2903/j.efsa.2014.3540
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	Not reported	6.0000000000	h	yes	not applicable	Inconclusive		direct evidence-cytotoxicity	RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	50	Male	oral: gavage	48.0000000000	D	yes	not applicable	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	42.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	18.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Triazoxide	276-668-4	72459-58-6	single chemical entity	Component is identical to the substance	Triazoxide	276-668-4	72459-58-6	7-chloro-3-(1H-imidazol-1-yl)-1,2,4-benzotriazine 1-oxide	Triazoxide	C10H6ClN5O	Clc1ccc2nc(n[n+]([O-])c2c1)n3ccnc3	InChI=1S/C10H6ClN5O/c11-7-1-2-8-9(5-7)16(17)14-10(13-8)15-4-3-12-6-15/h1-6H	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	6.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Triazoxide	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triazoxide	01Mar2011	2011	doi:10.2903/j.efsa.2011.2018
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	hepatocytes			Not reported			yes, concurrent no treatment	with	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	hepatocytes			Not reported			yes, concurrent no treatment	without	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: unspecified	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male/Female	Not reported	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male/Female	Not reported	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Tribenuron-methyl		101200-48-0	single chemical entity	Component is identical to the substance	Tribenuron-methyl		101200-48-0	methyl2-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)-methylcarbamoyl]sulfamoyl]benzoate	Tribenuron-methyl	C15-H17-N5-O6-S	CC1=NC(=NC(=N1)OC)N(C)C(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OC	InChI=1S/C15H17N5O6S/c1-9-16-13(18-14(17-9)26-4)20(2)15(22)19-27(23,24)11-8-6-5-7-10(11)12(21)25-3/h5-8H,1-4H3,(H,19,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male/Female	Not reported	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Sweden	Tribenuron-methyl	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tribenuron	31Mar2005	2005	doi:10.2903/j.efsa.2005.15r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Inconclusive			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Inconclusive			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Trichlorfon	200-149-3	52-68-6	single chemical entity	Component is identical to the substance	Trichlorfon	200-149-3	52-68-6	2,2,2-Trichloro-1-dimethoxyphosphorylethanol	Trichlorfon	C4H8Cl3O4P	COP(=O)(C(C(Cl)(Cl)Cl)O)OC	InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	50	Male	oral: gavage	48.0000000000	D	yes	not applicable	Negative			RMS: Spain	Trichlorfon	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trichlorfon	15Jun2006	2006	doi:10.2903/j.efsa.2006.76r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M17			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: unspecified	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is part of a group assessment	Triclopyr-butoxyethyl ester	265-024-8	64470-88-8	2-Butoxyethyl 2-(3,5,6-trichloropyridin-2-yl)oxyacetate	Triclopyr-butoxyethyl ester	C13H16Cl3NO4	CCCCOCCOC(=O)COC1=NC(=C(C=C1Cl)Cl)Cl	InChI=1S/C13H16Cl3NO4/c1-2-3-4-19-5-6-20-11(18)8-21-13-10(15)7-9(14)12(16)17-13/h7H,2-6,8H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		direct evidence-cytotoxicity	RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is identical to the substance	Triclopyr	259-597-3	55335-06-3	[(3,5,6-trichloropyridin-2-yl)oxy]acetic acid	Triclopyr	C7H4Cl3NO3	O=C(O)COC1=C(Cl)C=C(Cl)C(Cl)=N1	InChI=1S/C7H4Cl3NO3/c8-3-1-4(9)7(11-6(3)10)14-2-5(12)13/h1H,2H2,(H,12,13)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	CF-1	30	Male	oral: feed	9.0000000000	week	yes	not applicable	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triclopyr	259-597-3	55335-06-3	single chemical entity	Component is a metabolite of the substance	3,5,6-Trichloro-2-pyridinol	229-405-2	6515-38-4	3,5,6-trichloro-1H-pyridin-2-one	Not in list	C5H2Cl3NO	C1=C(C(=O)NC(=C1Cl)Cl)Cl	InChI=1S/C5H2Cl3NO/c6-2-1-3(7)5(10)9-4(2)8/h1H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Ireland	Triclopyr	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triclopyr	19Jan2006	2006	doi:10.2903/j.efsa.2006.56r
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	no data	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	no data	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	12.0000000000	h	no data	not applicable	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Triflumizole		99387-89-0	single chemical entity	Component is identical to the substance	Triflumizole		99387-89-0	N-[4-chloro-2-(trifluoromethyl)phenyl]-1-imidazol-1-yl-2-propoxyethanimine	Triflumizole	C15H15ClF3N3O	CCCOCC(=NC1=C(C=C(C=C1)Cl)C(F)(F)F)N2C=CN=C2	InChI=1S/C15H15ClF3N3O/c1-2-7-23-9-14(22-6-5-20-10-22)21-13-4-3-11(16)8-12(13)15(17,18)19/h3-6,8,10H,2,7,9H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative			RMS: The Netherlands	Triflumizole	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumizole	14Dec2009	2009	doi:10.2903/j.efsa.2009.1415
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male/Female	oral: gavage	18.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Zeta-cypermethrin	257-842-9	52315-07-8	single chemical entity	Component is identical to the substance	Zeta-Cypermethrin	257-842-9	52315-07-8	(S)-alpha-cyano-3-phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2 dimethylcyclopropanecarboxylate	Zeta-Cypermethrin	C22H19Cl2NO3	CC1(C(C1C(=O)OC(C#N)C2=CC(=CC=C2)OC3=CC=CC=C3)C=C(Cl)Cl)C	InChI=1S/C22H19Cl2NO3/c1-22(2)17(12-19(23)24)20(22)21(26)28-18(13-25)14-7-6-10-16(11-14)27-15-8-4-3-5-9-15/h3-12,17-18,20H,1-2H3/t17?,18-,20?/m1/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male/Female	oral: gavage	30.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Belgium	Zeta-cypermethrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance zeta-cypermethrin.	15Jan2009	2009	doi:10.2903/j.efsa.2009.196r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: unspecified	16.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is identical to the substance	Trinexapac-ethyl		95266-40-3	Ethyl 4-[cyclopropyl(hydroxy)methylidene]-3,5-dioxocyclohexane-1-carboxylate	Trinexapac-Ethyl	C13H16O5	CCOC(=O)C1CC(=O)C(=C(C2CC2)O)C(=O)C1	InChI=1S/C13H16O5/c1-2-18-13(17)8-5-9(14)11(10(15)6-8)12(16)7-3-4-7/h7-8,16H,2-6H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: unspecified	16.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Tricarballylic acid	202-733-3	99-14-9	1,2,3-propanetricarboxylic acid (tricarballylic acid)	Not in list	C6H8O6	C(C(CC(=O)O)C(=O)O)C(=O)O	InChI=1S/C6H8O6/c7-4(8)1-3(6(11)12)2-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA313458)			(2-(4-cyclopropyl-2,4-dioxobutyl)-succinic acid)	Trinexapac-ethyl metabolite (CGA313458)	C11H14O6	O=C(CC(CC(O)=O)C(O)=O)\C=C(/O)C1CC1	InChI=1/C11H14O6/c12-8(5-9(13)6-1-2-6)3-7(11(16)17)4-10(14)15/h5-7,13H,1-4H2,(H,14,15)(H,16,17)/b9-5-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Trinexapac-ethyl		95266-40-3	single chemical entity	Component is a metabolite of the substance	Trinexapac-ethyl metabolite (CGA329773)			4-cyclopropanecarbonyl-3,5-dihydroxybenzoic acid oxo-butyl)-succinic acid	Trinexapac-ethyl metabolite (CGA329773)	C11H10O5	O=C(c1c(O)cc(cc1O)C(=O)O)C2CC2	InChI=1S/C11H10O5/c12-7-3-6(11(15)16)4-8(13)9(7)10(14)5-1-2-5/h3-5,12-13H,1-2H2,(H,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: The Netherlands	Trinexapac-ethyl	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance trinexapac	10Jan2006	2006	doi:10.2903/j.efsa.2006.57r
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is identical to the substance	Triticonazole		131983-72-7	5-(4-chlorobenzylidene)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Triticonazole	C17H20ClN3O	OC1(CN2N=CN=C2)C(C)(C)CCC1=CC3=CC=C(Cl)C=C3	InChI=1S/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406341			[(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol]	Not in list	C18H22ClN3O2	O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C	InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406341			[(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol]	Not in list	C18H22ClN3O2	O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C	InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406341			[(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol]	Not in list	C18H22ClN3O2	O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C	InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406341			[(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol]	Not in list	C18H22ClN3O2	O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C	InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406341			[(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol]	Not in list	C18H22ClN3O2	O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C	InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406341			[(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol]	Not in list	C18H22ClN3O2	O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C	InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406341			[(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol]	Not in list	C18H22ClN3O2	O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C	InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406341			[(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol]	Not in list	C18H22ClN3O2	O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C	InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406341			[(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol]	Not in list	C18H22ClN3O2	O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C	InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406341			[(E)-2-(4-chlorobenzylidene)-5,5-dimethyl-1-(1,2,4-triazol-1-ylmethyl)cyclopen-tan-1,3-trans-diol]	Not in list	C18H22ClN3O2	O[C@H](Cn1cncn1)C3\C(=C\c2ccc(Cl)cc2)[C@H](O)C[C@]3(C)C	InChI=1/C18H22ClN3O2/c1-18(2)8-15(23)14(7-12-3-5-13(19)6-4-12)17(18)16(24)9-22-11-20-10-21-22/h3-7,10-11,15-17,23-24H,8-9H2,1-2H3/b14-7+/t15-,16-,17?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406203			(5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Not in list	C17H20ClN3O	Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2	InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406203			(5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Not in list	C17H20ClN3O	Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2	InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406203			(5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Not in list	C17H20ClN3O	Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2	InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406203			(5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Not in list	C17H20ClN3O	Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2	InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406203			(5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Not in list	C17H20ClN3O	Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2	InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406203			(5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Not in list	C17H20ClN3O	Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2	InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406203			(5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Not in list	C17H20ClN3O	Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2	InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406203			(5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Not in list	C17H20ClN3O	Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2	InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406203			(5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Not in list	C17H20ClN3O	Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2	InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Triticonazole		131983-72-7	single chemical entity	Component is a metabolite of the substance	Triticonazole metabolite RPA406203			(5E)-5-[(4-chlorophenyl)methylidene]-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol	Not in list	C17H20ClN3O	Clc1ccc(cc1)\C=C3/CCC(C)(C)C3(O)Cn2cncn2	InChI=1/C17H20ClN3O/c1-16(2)8-7-14(9-13-3-5-15(18)6-4-13)17(16,22)10-21-12-19-11-20-21/h3-6,9,11-12,22H,7-8,10H2,1-2H3/b14-9+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Triticonazole	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triticonazole	18Aug2005	2005	doi:10.2903/j.efsa.2005.33ar
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	11	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is identical to the substance	Valiphenal		283159-90-0	Methyl 3-(4-chlorophenyl)-3-[[(2S)-3-methyl-2-(propan-2-yloxycarbonylamino) butanoyl]amino]propanoate	Valifenalate	C19H27ClN2O5	CC(C)[C@@H](C(=O)NC(CC(=O)OC)C1=CC=C(C=C1)Cl)NC(=O)OC(C)C	InChI=1S/C19H27ClN2O5/c1-11(2)17(22-19(25)27-12(3)4)18(24)21-15(10-16(23)26-5)13-6-8-14(20)9-7-13/h6-9,11-12,15,17H,10H2,1-5H3,(H,21,24)(H,22,25)/t15?,17-/m0/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	11	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	4-Chlorobenzoic acid	200-805-9	74-11-3	4-Chlorobenzoic acid	Not in list	C7H5ClO2	C1=CC(=CC=C1C(=O)O)Cl	InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	4-Chlorobenzoic acid	200-805-9	74-11-3	4-Chlorobenzoic acid	Not in list	C7H5ClO2	C1=CC(=CC=C1C(=O)O)Cl	InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	4-Chlorobenzoic acid	200-805-9	74-11-3	4-Chlorobenzoic acid	Not in list	C7H5ClO2	C1=CC(=CC=C1C(=O)O)Cl	InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	4-Chlorobenzoic acid	200-805-9	74-11-3	4-Chlorobenzoic acid	Not in list	C7H5ClO2	C1=CC(=CC=C1C(=O)O)Cl	InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid			(3RS)-3-(4-chlorophenyl)-3-{[N-(isopropoxycarbonyl)-L-valyl]amino}propanoic acid	Not in list	C18H25ClN2O5	Clc1ccc(cc1)C(NC(=O)[C@@H](NC(=O)OC(C)C)C(C)C)CC(O)=O	InChI=1/C18H25ClN2O5/c1-10(2)16(21-18(25)26-11(3)4)17(24)20-14(9-15(22)23)12-5-7-13(19)8-6-12/h5-8,10-11,14,16H,9H2,1-4H3,(H,20,24)(H,21,25)(H,22,23)/t14?,16-/m0/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	4-Chlorobenzoic acid	200-805-9	74-11-3	4-Chlorobenzoic acid	Not in list	C7H5ClO2	C1=CC(=CC=C1C(=O)O)Cl	InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Valiphenal		283159-90-0	single chemical entity	Component is a metabolite of the substance	4-Chlorobenzoic acid	200-805-9	74-11-3	4-Chlorobenzoic acid	Not in list	C7H5ClO2	C1=CC(=CC=C1C(=O)O)Cl	InChI=1S/C7H5ClO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Hungary	Valifenalate (Formerly Valiphenal) (Final Addendum)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance valifenalate.	20Jun2013	2013	doi:10.2903/j.efsa.2013.3253
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Positive			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Positive			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline required	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	not applicable	Positive			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Not reported	3	Female	oral: gavage	2.0000000000	D	yes	not applicable	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	Equivalent or similar to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	ICR	5	Female	oral: gavage	5.0000000000	D	yes	not applicable	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	4	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Positive		no evidence	RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	Rat (as animal)	Wistar	15	Male	oral: gavage	5.0000000000	D	yes	not applicable	Negative			RMS: Greece	Trifluralin	2003	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	30	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	30	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	30	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is a metabolite of the substance	1-(-4’-chlorophenyl)-1,4-dihydro-5-(2’’-hydroxy-ethoxy)-4-oxo-cinnoline-3-carboxylate			1-(4-chlorophenyl)-5-(2-hydroxyethoxy)-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid	Sintofen metabolite (SC 3095)	C17H13ClN2O5	OC(=O)C/2=N/N(c1ccc(Cl)cc1)c3cccc(OCCO)c3C\2=O	InChI=1/C17H13ClN2O5/c18-10-4-6-11(7-5-10)20-12-2-1-3-13(25-9-8-21)14(12)16(22)15(19-20)17(23)24/h1-7,21H,8-9H2,(H,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	7	Male	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is identical to the substance	Triasulfuron	617-298-9	82097-50-5	1-[2-(2-chloroethoxy)phenylsulfonyl]-3-(4-methoxy-6-methyl-1,3,5-triazin-2-yl)urea	Triasulfuron	C14H16ClN5O5S	CC1=NC(=NC(=N1)OC)NC(=O)NS(=O)(=O)C2=CC=CC=C2OCCCl	InChI=1S/C14H16ClN5O5S/c1-9-16-12(19-14(17-9)24-2)18-13(21)20-26(22,23)11-6-4-3-5-10(11)25-8-7-15/h3-6H,7-8H2,1-2H3,(H2,16,17,18,19,20,21)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	7	Male	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Triasulfuron	617-298-9	82097-50-5	single chemical entity	Component is a metabolite of the substance	[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid			[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl]sulfamic acid	Not in list	C6H9N5O5S	Cc1nc(NC(=O)NS(=O)(=O)O)nc(OC)n1	InChI=1/C6H9N5O5S/c1-3-7-4(10-6(8-3)16-2)9-5(12)11-17(13,14)15/h1-2H3,(H,13,14,15)(H2,7,8,9,10,11,12)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Triasulfuron (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triasulfuron	09Jan2015	2015	doi:10.2903/j.efsa.2015.3958
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Ambiguous			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Ambiguous		indirect evidence-systemic toxicity	RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	intraperitoneal	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	12.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Tralkoxydim	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is identical to the substance	Tralkoxydim		87820-88-0	2-[1-(Ethoxyamino)propylidene]-5-(2,4,6-trimethylphenyl)cyclohexane-1, 3-dione	Tralkoxydim	C20H27NO3	CCC(=C1C(=O)CC(CC1=O)C2=C(C=C(C=C2C)C)C)NOCC	InChI=1S/C20H27NO3/c1-6-16(21-24-7-2)20-17(22)10-15(11-18(20)23)19-13(4)8-12(3)9-14(19)5/h8-9,15,21H,6-7,10-11H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is identical to the substance	Rimsulfuron		122931-48-0	N-[(4,6-dimethoxypyrimidin-2-yl)carbamoyl]-3-(ethylsulfonyl)pyridine-2-sulfonamide	Rimsulfuron	C14H17N5O7S2	O=S(C1=NC=CC=C1S(CC)(=O)=O)(NC(NC2=NC(OC)=CC(OC)=N2)=O)=O	InChI=1S/C14H17N5O7S2/c1-4-27(21,22)9-6-5-7-15-12(9)28(23,24)19-14(20)18-13-16-10(25-2)8-11(17-13)26-3/h5-8H,4H2,1-3H3,(H2,16,17,18,19,20)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	small colonies		RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	large colonies		RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	small colonies		RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	large colonies		RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Sodium silver thiosulfate			single chemical entity	Component is identical to the substance	Sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions)				Not in list				inorganic	no structure			DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	6	Male	oral: gavage	3.0000000000	month	yes	not applicable	Negative			RMS: The Netherlands	Silver thiosulphate	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sodium silver thiosulfate (in solution with a ratio of at least 1 to 8 silver to thiosulfate ions).	03Oct2013	2013	doi:10.2903/j.efsa.2013.3136
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(3-(ethylsulfonyl)-2-pyridinesulfonamide			3-(ethylsulfonyl)pyridine-2-sulfonamide	Not in list	C7H10N2O4S2	O=S(N)(=O)c1ncccc1S(=O)(=O)CC	InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(3-(ethylsulfonyl)-2-pyridinesulfonamide			3-(ethylsulfonyl)pyridine-2-sulfonamide	Not in list	C7H10N2O4S2	O=S(N)(=O)c1ncccc1S(=O)(=O)CC	InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(3-(ethylsulfonyl)-2-pyridinesulfonamide			3-(ethylsulfonyl)pyridine-2-sulfonamide	Not in list	C7H10N2O4S2	O=S(N)(=O)c1ncccc1S(=O)(=O)CC	InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(3-(ethylsulfonyl)-2-pyridinesulfonamide			3-(ethylsulfonyl)pyridine-2-sulfonamide	Not in list	C7H10N2O4S2	O=S(N)(=O)c1ncccc1S(=O)(=O)CC	InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(3-(ethylsulfonyl)-2-pyridinesulfonamide			3-(ethylsulfonyl)pyridine-2-sulfonamide	Not in list	C7H10N2O4S2	O=S(N)(=O)c1ncccc1S(=O)(=O)CC	InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(3-(ethylsulfonyl)-2-pyridinesulfonamide			3-(ethylsulfonyl)pyridine-2-sulfonamide	Not in list	C7H10N2O4S2	O=S(N)(=O)c1ncccc1S(=O)(=O)CC	InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(3-(ethylsulfonyl)-2-pyridinesulfonamide			3-(ethylsulfonyl)pyridine-2-sulfonamide	Not in list	C7H10N2O4S2	O=S(N)(=O)c1ncccc1S(=O)(=O)CC	InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(3-(ethylsulfonyl)-2-pyridinesulfonamide			3-(ethylsulfonyl)pyridine-2-sulfonamide	Not in list	C7H10N2O4S2	O=S(N)(=O)c1ncccc1S(=O)(=O)CC	InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(3-(ethylsulfonyl)-2-pyridinesulfonamide			3-(ethylsulfonyl)pyridine-2-sulfonamide	Not in list	C7H10N2O4S2	O=S(N)(=O)c1ncccc1S(=O)(=O)CC	InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(3-(ethylsulfonyl)-2-pyridinesulfonamide			3-(ethylsulfonyl)pyridine-2-sulfonamide	Not in list	C7H10N2O4S2	O=S(N)(=O)c1ncccc1S(=O)(=O)CC	InChI=1/C7H10N2O4S2/c1-2-14(10,11)6-4-3-5-9-7(6)15(8,12)13/h3-5H,2H2,1H3,(H2,8,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Rimsulfuron (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Rimsulfuron		122931-48-0	single chemical entity	Component is a metabolite of the substance	(N-(4,6-dimethoxy-2-pyrimidinyl)-N-((3-ethylsulfonyl)-2-pyridinyl)urea)			1-(4,6-dimethoxypyrimidin-2-yl)-1-[3-(ethylsulfonyl)pyridin-2-yl]urea	Not in list	C14H17N5O5S	O=C(N)N(c1nc(cc(OC)n1)OC)c2ncccc2S(=O)(=O)CC	InChI=1/C14H17N5O5S/c1-4-25(21,22)9-6-5-7-16-12(9)19(13(15)20)14-17-10(23-2)8-11(18-14)24-3/h5-8H,4H2,1-3H3,(H2,15,20)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Rimsulfuron (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer reviewof the pesticide risk assessment of the active substance rimsulfuron	31Aug2005	2005	doi:10.2903/j.efsa.2005.45r
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	mixture or formulation	Component is identical to the substance	Spinetoram		935545-74-7	(3aR,5aR,9S,13S,14R,16aS,16bR)-13-{[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy}-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl 6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranoside	Spinetoram (XDE-175)	C42H69NO10	CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@@H]3[C@H](C2CC(=O)O1)CC[C@H]4[C@H]3CC(C4)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OCC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C	InChI=1S/C42H69NO10/c1-10-27-13-12-14-35(53-37-18-17-34(43(6)7)24(4)49-37)23(3)38(45)33-21-31-29(32(33)22-36(44)51-27)16-15-26-19-28(20-30(26)31)52-42-41(47-9)40(48-11-2)39(46-8)25(5)50-42/h21,23-32,34-35,37,39-42H,10-20,22H2,1-9H3/t23-,24-,25+,26-,27+,28?,29-,30-,31-,32?,34+,35+,37+,39+,40-,41-,42+/m1/s1	organic	representative compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-demethyl-175-J			(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl  6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside	N-demethyl-175-J	C41H67NO10	CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C	InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-demethyl-175-J			(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl  6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside	N-demethyl-175-J	C41H67NO10	CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C	InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-demethyl-175-J			(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl  6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside	N-demethyl-175-J	C41H67NO10	CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C	InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-demethyl-175-J			(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl  6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside	N-demethyl-175-J	C41H67NO10	CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C	InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-demethyl-175-J			(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl  6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside	N-demethyl-175-J	C41H67NO10	CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C	InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-demethyl-175-J			(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl  6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside	N-demethyl-175-J	C41H67NO10	CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C	InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-demethyl-175-J			(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl  6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside	N-demethyl-175-J	C41H67NO10	CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C	InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-demethyl-175-J			(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl  6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside	N-demethyl-175-J	C41H67NO10	CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C	InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-demethyl-175-J			(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl  6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside	N-demethyl-175-J	C41H67NO10	CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C	InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-demethyl-175-J			(2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-9-ethyl-14-methyl-13-{[(2S,5S,6R)-6-methyl-5-(methylamino)tetrahydro-2H-pyran-2-yl]oxy}-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-2-yl  6-deoxy-3-O-ethyl-2,4-di-O-methyl-alpha-L-mannopyranoside	N-demethyl-175-J	C41H67NO10	CN[C@H]1CCC(O[C@@H]1C)O[C@H]6CCC[C@H](CC)OC(=O)C[C@@H]5C(=C/[C@@H]2[C@H]5CC[C@@H]3C[C@H](C[C@@H]23)O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]4OC)\C(=O)[C@@H]6C	InChI=1/C41H67NO10/c1-9-26-12-11-13-34(52-36-17-16-33(42-6)23(4)48-36)22(3)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(46-8)39(47-10-2)38(45-7)24(5)49-41/h20,22-31,33-34,36,38-42H,9-19,21H2,1-8H3/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34+,36-,38+,39-,40-,41+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-J			N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C41H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-J			N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C41H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-J			N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C41H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-J			N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C41H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-J			N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C41H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-J			N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C41H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-J			N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C41H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-J			N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C41H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-J			N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C41H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-J			N-[(2R,3S,6R)-6-({(2R,3aR,5aR,5bS,9S,14R,16aS,16bR)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-14-methyl-7,15-dioxo-2,3,3a,4,5,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-octadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C41H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3CC[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C41H65NO11/c1-8-26-11-10-12-34(53-36-16-15-33(42-21-43)23(4)49-36)22(3)37(45)32-19-30-28(31(32)20-35(44)51-26)14-13-25-17-27(18-29(25)30)52-41-40(47-7)39(48-9-2)38(46-6)24(5)50-41/h19,21-31,33-34,36,38-41H,8-18,20H2,1-7H3,(H,42,43)/t22-,23-,24+,25-,26+,27-,28-,29-,30-,31+,33+,34?,36+,38+,39-,40-,41?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-L			N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C42H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-L			N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C42H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-L			N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C42H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-L			N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C42H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-L			N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C42H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-L			N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C42H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-L			N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C42H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-L			N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C42H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-L			N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C42H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Spinetoram		935545-74-7	single chemical entity	Component is a metabolite of the substance	N-formyl-175-L			N-[(2R,3S,6R)-6-({(2S,3aR,5aS,5bS,9S,14R,16aS,16bS)-2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-L-mannopyranosyl)oxy]-9-ethyl-4,14-dimethyl-7,15-dioxo-2,3,3a,5a,5b,6,7,9,10,11,12,13,14,15,16a,16b-hexadecahydro-1H-as-indaceno[3,2-d]oxacyclododecin-13-yl}oxy)-2-methyloxan-3-yl]formamide	Not in list	C42H65NO11	O=CN[C@H]1CC[C@@H](O[C@@H]1C)OC2CCC[C@H](CC)OC(=O)C[C@@H]3C(=C[C@@H]4[C@H]3C=C(C)[C@@H]5C[C@H](C[C@H]54)OC6O[C@@H](C)[C@H](OC)[C@@H](OCC)[C@H]6OC)C(=O)[C@@H]2C	InChI=1S/C42H65NO11/c1-9-26-12-11-13-35(54-37-15-14-34(43-21-44)24(5)50-37)23(4)38(46)33-19-31-29(32(33)20-36(45)52-26)16-22(3)28-17-27(18-30(28)31)53-42-41(48-8)40(49-10-2)39(47-7)25(6)51-42/h16,19,21,23-32,34-35,37,39-42H,9-15,17-18,20H2,1-8H3,(H,43,44)/t23-,24-,25+,26+,27-,28+,29-,30-,31-,32+,34+,35?,37+,39+,40-,41-,42?/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	XDE-175 (spinetoram)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spinetoram.	08May2013	2013	doi:10.2903/j.efsa.2013.3220
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Positive			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	SwissWebster	130	Male/Female	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	SwissWebster	130	Male/Female	intraperitoneal	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	SwissWebster	130	Male/Female	intraperitoneal	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	48	Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Quinoclamine	220-529-2	2797-51-5	single chemical entity	Component is identical to the substance	Quinoclamine	220-529-2	2797-51-5	2-amino-3-chloro-1,4-naphthoquinone	Quinoclamine	C10H6ClNO2	NC1=C(Cl)C(=O)c2ccccc2C1=O	InChI=1/C10H6ClNO2/c11-7-8(12)10(14)6-4-2-1-3-5(6)9(7)13/h1-4H,12H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	48	Male	oral: gavage	12.0000000000	h	yes	not applicable	Negative			RMS: Sweden	Quinoclamine	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quinoclamine	12Dec2007	2007	doi:10.2903/j.efsa.2007.117r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	House mouse (as animal)	B6C3F1			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	6	Male	oral: gavage	18.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	6	Male	oral: gavage	42.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	Syrian	44	Male/Female	oral: feed	7.0000000000	week	yes	not applicable	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No data	Acceptable	Hamster (as animal)	Syrian	44	Male/Female	oral: feed	14.0000000000	week	yes	not applicable	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	House mouse (as animal)	B6C3F1	6	Male	oral: gavage	16.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is identical to the substance	Tri-allate	218-962-7	2303-17-5	S-(2,3,3-trichloroprop-2-en-1-yl) diisopropylthiocarbamate	Tri-allate	C10H16Cl3NOS	CC(C)N(C(C)C)C(=O)SCC(=C(Cl)Cl)Cl	InChI=1/C10H16Cl3NOS/c1-6(2)14(7(3)4)10(15)16-5-8(11)9(12)13/h6-7H,5H2,1-4H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	House mouse (as animal)	B6C3F1	6	Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	with	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Tri-allate	218-962-7	2303-17-5	single chemical entity	Component is a metabolite of the substance	2,3,3-trichloroprop-2-ene-sulfonic acid			2,3,3-trichloroprop-2-ene-1-sulfonic acid	Not in list	C3H3Cl3O3S	C(C(=C(Cl)Cl)Cl)S(=O)(=O)O	InChI=1S/C3H3Cl3O3S/c4-2(3(5)6)1-10(7,8)9/h1H2,(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The United Kingdom	Tri-allate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tri-allate	16Jul2009	2009	doi:10.2903/j.efsa.2009.181r
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2,4-dicarboxylic acid			3-sulfamoylthiophene-2,4-dicarboxylic acid	Not in list	C6H5NO6S2	O=S(N)(=O)c1c(scc1C(=O)O)C(O)=O	InChI=1/C6H5NO6S2/c7-15(12,13)4-2(5(8)9)1-14-3(4)6(10)11/h1H,(H,8,9)(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2,4-dicarboxylic acid			3-sulfamoylthiophene-2,4-dicarboxylic acid	Not in list	C6H5NO6S2	O=S(N)(=O)c1c(scc1C(=O)O)C(O)=O	InChI=1/C6H5NO6S2/c7-15(12,13)4-2(5(8)9)1-14-3(4)6(10)11/h1H,(H,8,9)(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is identical to the substance	Thiencarbazone-methyl		317815-83-1	methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carboxamidosulfonyl]-5-methylthiophene-3-carboxylate	Thiencarbazone-methyl	C12H14N4O7S2	CC1=C(C(=CS1)C(=O)OC)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C12H14N4O7S2/c1-6-8(7(5-24-6)9(17)22-3)25(20,21)14-10(18)16-12(19)15(2)11(13-16)23-4/h5H,1-4H3,(H,14,18)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2,4-dicarboxylic acid			3-sulfamoylthiophene-2,4-dicarboxylic acid	Not in list	C6H5NO6S2	O=S(N)(=O)c1c(scc1C(=O)O)C(O)=O	InChI=1/C6H5NO6S2/c7-15(12,13)4-2(5(8)9)1-14-3(4)6(10)11/h1H,(H,8,9)(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2,4-dicarboxylic acid			3-sulfamoylthiophene-2,4-dicarboxylic acid	Not in list	C6H5NO6S2	O=S(N)(=O)c1c(scc1C(=O)O)C(O)=O	InChI=1/C6H5NO6S2/c7-15(12,13)4-2(5(8)9)1-14-3(4)6(10)11/h1H,(H,8,9)(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	3-sulfamoylthiophene-2,4-dicarboxylic acid			3-sulfamoylthiophene-2,4-dicarboxylic acid	Not in list	C6H5NO6S2	O=S(N)(=O)c1c(scc1C(=O)O)C(O)=O	InChI=1/C6H5NO6S2/c7-15(12,13)4-2(5(8)9)1-14-3(4)6(10)11/h1H,(H,8,9)(H,10,11)(H2,7,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	6	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	4-{[(3-methoxy-4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylic acid			4-[(3-methoxy-4-methyl-5-oxo-1,2,4-triazole-1-carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylic acid	Not in list	C11H12N4O7S2	CC1=C(C(=CS1)C(=O)O)S(=O)(=O)NC(=O)N2C(=O)N(C(=N2)OC)C	InChI=1S/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)17)24(20,21)13-9(18)15-11(19)14(2)10(12-15)22-3/h4H,1-3H3,(H,13,18)(H,16,17)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate			methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate	Not in list	C7H9NO4S2	O=S(N)(=O)c1c(C)scc1C(=O)OC	InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate			methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate	Not in list	C7H9NO4S2	O=S(N)(=O)c1c(C)scc1C(=O)OC	InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate			methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate	Not in list	C7H9NO4S2	O=S(N)(=O)c1c(C)scc1C(=O)OC	InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate			methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate	Not in list	C7H9NO4S2	O=S(N)(=O)c1c(C)scc1C(=O)OC	InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate			methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate	Not in list	C7H9NO4S2	O=S(N)(=O)c1c(C)scc1C(=O)OC	InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate			methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate	Not in list	C7H9NO4S2	O=S(N)(=O)c1c(C)scc1C(=O)OC	InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate			methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate	Not in list	C7H9NO4S2	O=S(N)(=O)c1c(C)scc1C(=O)OC	InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate			methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate	Not in list	C7H9NO4S2	O=S(N)(=O)c1c(C)scc1C(=O)OC	InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate			methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate	Not in list	C7H9NO4S2	O=S(N)(=O)c1c(C)scc1C(=O)OC	InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate			methyl 5-methyl-4-sulfamoylthiophene-3-carboxylate	Not in list	C7H9NO4S2	O=S(N)(=O)c1c(C)scc1C(=O)OC	InChI=1/C7H9NO4S2/c1-4-6(14(8,10)11)5(3-13-4)7(9)12-2/h3H,1-2H3,(H2,8,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Thiencarbazone-methyl		317815-83-1	single chemical entity	Component is a metabolite of the substance	methyl 4-({[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]amino}sulfonyl)-5-methylthiophene-3-carboxylate			methyl 4-{[(3-methoxy-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)carbonyl]sulfamoyl}-5-methylthiophene-3-carboxylate	Not in list	C11H12N4O7S2	O=S(=O)(NC(=O)N1/N=C(/OC)NC1=O)c2c(C)scc2C(=O)OC	InChI=1/C11H12N4O7S2/c1-5-7(6(4-23-5)8(16)21-2)24(19,20)14-11(18)15-10(17)12-9(13-15)22-3/h4H,1-3H3,(H,14,18)(H,12,13,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thiencarbazone-methyl (BYH 18636)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiencarbazone-methyl	01Jul2013	2013	doi:10.2903/j.efsa.2013.3270
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is identical to the substance	Triflumuron	264-980-3	64628-44-0	2-chloro-N-{[4-(trifluoromethoxy)phenyl]carbamoyl}benzamide	Triflumuron	C15H10ClF3N2O3	O=C(C1=CC=CC=C1Cl)NC(NC(C=C2)=CC=C2OC(F)(F)F)=O	InChI=1S/C15H10ClF3N2O3/c16-12-4-2-1-3-11(12)13(22)21-14(23)20-9-5-7-10(8-6-9)24-15(17,18)19/h1-8H,(H2,20,21,22,23)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is a metabolite of the substance	4-Trifluoro-methoxyaniline	207-317-5	461-82-5	4-(Trifluoromethoxy)aniline	4-Trifluoro-methoxyaniline	C7H6F3NO	C1=CC(=CC=C1N)OC(F)(F)F	InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is a metabolite of the substance	4-Trifluoro-methoxyaniline	207-317-5	461-82-5	4-(Trifluoromethoxy)aniline	4-Trifluoro-methoxyaniline	C7H6F3NO	C1=CC(=CC=C1N)OC(F)(F)F	InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is a metabolite of the substance	4-Trifluoro-methoxyaniline	207-317-5	461-82-5	4-(Trifluoromethoxy)aniline	4-Trifluoro-methoxyaniline	C7H6F3NO	C1=CC(=CC=C1N)OC(F)(F)F	InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is a metabolite of the substance	4-Trifluoro-methoxyaniline	207-317-5	461-82-5	4-(Trifluoromethoxy)aniline	4-Trifluoro-methoxyaniline	C7H6F3NO	C1=CC(=CC=C1N)OC(F)(F)F	InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is a metabolite of the substance	4-Trifluoro-methoxyaniline	207-317-5	461-82-5	4-(Trifluoromethoxy)aniline	4-Trifluoro-methoxyaniline	C7H6F3NO	C1=CC(=CC=C1N)OC(F)(F)F	InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is a metabolite of the substance	4-Trifluoro-methoxyaniline	207-317-5	461-82-5	4-(Trifluoromethoxy)aniline	4-Trifluoro-methoxyaniline	C7H6F3NO	C1=CC(=CC=C1N)OC(F)(F)F	InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is a metabolite of the substance	4-Trifluoro-methoxyaniline	207-317-5	461-82-5	4-(Trifluoromethoxy)aniline	4-Trifluoro-methoxyaniline	C7H6F3NO	C1=CC(=CC=C1N)OC(F)(F)F	InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Triflumuron	264-980-3	64628-44-0	single chemical entity	Component is a metabolite of the substance	4-Trifluoro-methoxyaniline	207-317-5	461-82-5	4-(Trifluoromethoxy)aniline	4-Trifluoro-methoxyaniline	C7H6F3NO	C1=CC(=CC=C1N)OC(F)(F)F	InChI=1S/C7H6F3NO/c8-7(9,10)12-6-3-1-5(11)2-4-6/h1-4H,11H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Triflumuron (Addendum 2 )	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance triflumuron	03Jan2011	2011	doi:10.2903/j.efsa.2011.1941
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Inconclusive			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		No data	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		No data	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		No data	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley		Male	oral: gavage	18.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley		Male	oral: gavage	4.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	16.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Famoxadone	603-520-1	131807-57-3	single chemical entity	Component is identical to the substance	Famoxadone	603-520-1	131807-57-3	3-anilino-5-methyl-5-(4-phenoxyphenyl)-1,3-oxazolidine-2,4-dione	Famoxadone	C22H18N2O4	CC1(C(=O)N(C(=O)O1)NC2=CC=CC=C2)C3=CC=C(C=C3)OC4=CC=CC=C4	InChI=1S/C22H18N2O4/c1-22(16-12-14-19(15-13-16)27-18-10-6-3-7-11-18)20(25)24(21(26)28-22)23-17-8-4-2-5-9-17/h2-15,23H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	4.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Famoxadone  (Renewal Assessment Report)	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance famoxadone	16Jul2015	2015	doi:10.2903/j.efsa.2015.4194
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			no data	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-ethyl	600-119-3	100646-51-3	single chemical entity	Component is identical to the substance	Quizalofop-P-ethyl	600-119-3	100646-51-3	Ethyl (2R)-2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Quizalofop-P-ethyl	C19H17ClN2O4	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=CN=C3C=C(C=CC3=N2)Cl	InChI=1S/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-7-15(8-6-14)26-18-11-21-17-10-13(20)4-9-16(17)22-18/h4-12H,3H2,1-2H3/t12-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	CD-1	18	Male	oral: gavage	5.0000000000	D	yes	not applicable	Negative			RMS: Finland	Quizalofop-p-ethyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Inconclusive	large colonies		RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Inconclusive	small colonies		RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	4.0000000000	h	yes	not applicable	Negative			RMS: Finland	Quizalofop-p-tefuryl (Final addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male	oral: gavage	16.0000000000	h	yes	not applicable	Negative			RMS: Finland	Quizalofop-p-tefuryl (Final addendum)	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Quizalofop-P-tefuryl	601-628-3	119738-06-6	single chemical entity	Component is identical to the substance	Quizalofop-P-tefuryl	601-628-3	119738-06-6	Oxolan-2-ylmethyl 2-[4-(6-chloroquinoxalin-2-yl)oxyphenoxy]propanoate	Not in list	C22H21ClN2O5	CC(C(=O)OCC1CCCO1)OC2=CC=C(C=C2)OC3=CN=C4C=C(C=CC4=N3)Cl	InChI=1S/C22H21ClN2O5/c1-14(22(26)28-13-18-3-2-10-27-18)29-16-5-7-17(8-6-16)30-21-12-24-20-11-15(23)4-9-19(20)25-21/h4-9,11-12,14,18H,2-3,10,13H2,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Finland	Quizalofop-p-tefuryl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance quizalofop-P (considered variants quizalofop-P-ethyl and quizalofop-P-tefuryl).	14Jul2009	2009	doi:10.2903/j.efsa.2009.205r
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	12.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	8	Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Foramsulfuron	605-666-1	173159-57-4	single chemical entity	Component is identical to the substance	Foramsulfuron	605-666-1  605-666-1	173159-57-4	1-(4,6-Dimethoxypyrimidin-2-yl)-3-(2-dimethylaminocarbonyl-5-formamidophenylsulfonyl)urea	Foramsulfuron	C17H20N6O7S	CN(C)C(=O)C1=C(C=C(C=C1)NC=O)S(=O)(=O)NC(=O)NC2=NC(=CC(=N2)OC)OC	InChI=1S/C17H20N6O7S/c1-23(2)15(25)11-6-5-10(18-9-24)7-12(11)31(27,28)22-17(26)21-16-19-13(29-3)8-14(20-16)30-4/h5-9H,1-4H3,(H,18,24)(H2,19,20,21,22,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	8	Male	oral: gavage	14.0000000000	h	yes	not applicable	Negative			RMS: Germany	Foramsulfuron (revised Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance foramsulfuron	10Mar2016	2016	doi:10.2903/j.efsa.2016.4421
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Ambiguous	no information		RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is identical to the substance	Tau-fluvalinate		102851-06-9	[cyano-(3-phenoxyphenyl)methyl](2R)-2-[2-chloro-4-(trifluoromethyl)anilino]-3-methylbutanoate	tau-Fluvalinate	C26H22ClF3N2O3	CC(C)[C@H](C(=O)OC(C#N)C1=CC(=CC=C1)OC2=CC=CC=C2)NC3=C(C=C(C=C3)C(F)(F)F)Cl	InChI=1S/C26H22ClF3N2O3/c1-16(2)24(32-22-12-11-18(14-21(22)27)26(28,29)30)25(33)35-23(15-31)17-7-6-10-20(13-17)34-19-8-4-3-5-9-19/h3-14,16,23-24,32H,1-2H3/t23?,24-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	6.0000000000	h	yes	not applicable	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	2-chloro-4-(trifluoromethyl)aniline			2-chloro-4-(trifluoromethyl)aniline	Not in list	C7H5ClF3N	c1cc(c(cc1C(F)(F)F)Cl)N	InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	2-chloro-4-(trifluoromethyl)aniline			2-chloro-4-(trifluoromethyl)aniline	Not in list	C7H5ClF3N	c1cc(c(cc1C(F)(F)F)Cl)N	InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	2-chloro-4-(trifluoromethyl)aniline			2-chloro-4-(trifluoromethyl)aniline	Not in list	C7H5ClF3N	c1cc(c(cc1C(F)(F)F)Cl)N	InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	2-chloro-4-(trifluoromethyl)aniline			2-chloro-4-(trifluoromethyl)aniline	Not in list	C7H5ClF3N	c1cc(c(cc1C(F)(F)F)Cl)N	InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	2-chloro-4-(trifluoromethyl)aniline			2-chloro-4-(trifluoromethyl)aniline	Not in list	C7H5ClF3N	c1cc(c(cc1C(F)(F)F)Cl)N	InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	2-chloro-4-(trifluoromethyl)aniline			2-chloro-4-(trifluoromethyl)aniline	Not in list	C7H5ClF3N	c1cc(c(cc1C(F)(F)F)Cl)N	InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	2-chloro-4-(trifluoromethyl)aniline			2-chloro-4-(trifluoromethyl)aniline	Not in list	C7H5ClF3N	c1cc(c(cc1C(F)(F)F)Cl)N	InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	2-chloro-4-(trifluoromethyl)aniline			2-chloro-4-(trifluoromethyl)aniline	Not in list	C7H5ClF3N	c1cc(c(cc1C(F)(F)F)Cl)N	InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	2-chloro-4-(trifluoromethyl)aniline			2-chloro-4-(trifluoromethyl)aniline	Not in list	C7H5ClF3N	c1cc(c(cc1C(F)(F)F)Cl)N	InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	2-chloro-4-(trifluoromethyl)aniline			2-chloro-4-(trifluoromethyl)aniline	Not in list	C7H5ClF3N	c1cc(c(cc1C(F)(F)F)Cl)N	InChI=1S/C7H5ClF3N/c8-5-3-4(7(9,10)11)1-2-6(5)12/h1-3H,12H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine			N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine	Not in list	C12H13ClF3NO2	Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F	InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine			N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine	Not in list	C12H13ClF3NO2	Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F	InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine			N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine	Not in list	C12H13ClF3NO2	Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F	InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine			N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine	Not in list	C12H13ClF3NO2	Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F	InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine			N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine	Not in list	C12H13ClF3NO2	Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F	InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine			N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine	Not in list	C12H13ClF3NO2	Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F	InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine			N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine	Not in list	C12H13ClF3NO2	Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F	InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine			N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine	Not in list	C12H13ClF3NO2	Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F	InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine			N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine	Not in list	C12H13ClF3NO2	Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F	InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine			N-[2-chloro-4-(trifluoromethyl)phenyl]-D-valine	Not in list	C12H13ClF3NO2	Clc1cc(ccc1NC(C(O)=O)C(C)C)C(F)(F)F	InChI=1/C12H13ClF3NO2/c1-6(2)10(11(18)19)17-9-4-3-7(5-8(9)13)12(14,15)16/h3-6,10,17H,1-2H3,(H,18,19)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Tau-fluvalinate		102851-06-9	single chemical entity	Component is a metabolite of the substance	3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile			3-{[2-chloro-4-(trifluoromethyl)phenyl]amino}-4-methyl-2-(3-phenoxyphenyl)pentanenitrile	Not in list	C25H22ClF3N2O	Clc3cc(ccc3NC(C(C#N)c2cccc(Oc1ccccc1)c2)C(C)C)C(F)(F)F	InChI=1/C25H22ClF3N2O/c1-16(2)24(31-23-12-11-18(14-22(23)26)25(27,28)29)21(15-30)17-7-6-10-20(13-17)32-19-8-4-3-5-9-19/h3-14,16,21,24,31H,1-2H3/t21?,24-/m0/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Tau-fluvalinate	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tau-fluvalinate	07Jul2010	2010	doi:10.2903/j.efsa.2010.1645
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	no information		RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium 5-nitroguaiacolate		67233-85-6	single chemical entity	Component is identical to the substance	Sodium 5-nitroguaiacolate		67233-85-6	Sodium;2-methoxy-5-nitrophenolate	Not in list	C7H6NNaO4	COC1=C(C=C(C=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C7H7NO4.Na/c1-12-7-3-2-5(8(10)11)4-6(7)9;/h2-4,9H,1H3;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium o-nitrophenolate	212-527-5	824-39-5	single chemical entity	Component is identical to the substance	Sodium o-nitrophenolate	212-527-5	824-39-5	Sodium;2-nitrophenolate	Not in list	C6H4NNaO3	C1=CC=C(C(=C1)[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	small colonies		RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	small colonies		RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Sodium p-nitrophenolate	212-536-4	824-78-2	single chemical entity	Component is identical to the substance	Sodium p-nitrophenolate	212-536-4	824-78-2	Sodium;4-nitrophenolate	Not in list	C6H4NNaO3	C1=CC(=CC=C1[N+](=O)[O-])[O-].[Na+]	InChI=1S/C6H5NO3.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4,8H;/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Greece	Sodium 5-nitroguaiacolate Sodium o-nitrophenolate and Sodium p-nitrophenolate	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substances sodium 5-nitroguaiacolate, sodium o-nitrophenolate and sodium p-nitrophenolate.	01Apr2009	2009	doi:10.2903/j.efsa.2009.191r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Ambiguous			RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Spirodiclofen		148477-71-8	single chemical entity	Component is identical to the substance	Spirodiclofen		148477-71-8	3-(3,5-dichlorophenyl)-2-oxo-1-oxaspiro[4.5]dec-3-en-4-yl 2,2-dimethylbutanoate	Spirodiclofen	C21H24Cl2O4	O=C2OC1(C(OC(C(CC)(C)C)=O)=C2C3=CC(Cl)=CC(Cl)=C3)CCCCC1	InChI=1S/C21H24Cl2O4/c1-4-20(2,3)19(25)26-17-16(13-10-14(22)12-15(23)11-13)18(24)27-21(17)8-6-5-7-9-21/h10-12H,4-9H2,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	16.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The Netherlands	Spirodiclofen	2004	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance spirodiclofen	06Aug2009	2009	doi:10.2903/j.efsa.2009.339r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	S211α			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	S138			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	S211α			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	S138			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Ambiguous			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: unspecified	6.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	6.0000000000	h	yes	not applicable	Positive			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Positive			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Positive			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	20	Male/Female	oral: unspecified	12.0000000000	h	yes	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	NMRI	20	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Not reported	8	Male	oral: unspecified	48.0000000000	h	yes	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	6	Male	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	6	Male	oral: unspecified	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	6	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	15	Male	oral: unspecified	48.0000000000	D	no data	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mouse spot test	in vivo	According to	OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test)	No	Acceptable	House mouse (as animal)	C57BL		Male/Female	oral: gavage	12.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mouse spot test	in vivo	According to	OECD Guideline 484 (Genetic Toxicology: Mouse Spot Test)	No	Acceptable	House mouse (as animal)	C57BL		Male/Female	oral: gavage	35.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar		No data	oral: feed	12.0000000000	D	yes	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar		No data	oral: feed	12.0000000000	D	yes	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vivo	No guideline followed	Not reported	Not applicable	Acceptable	Rat (as animal)	Wistar		No data	oral: feed	12.0000000000	D	yes	not applicable	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST			N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide	Not in list	C9H14N2O3S	O=S(=O)(Nc1ccc(cc1)CO)N(C)C	InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST			N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide	Not in list	C9H14N2O3S	O=S(=O)(Nc1ccc(cc1)CO)N(C)C	InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST			N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide	Not in list	C9H14N2O3S	O=S(=O)(Nc1ccc(cc1)CO)N(C)C	InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST			N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide	Not in list	C9H14N2O3S	O=S(=O)(Nc1ccc(cc1)CO)N(C)C	InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST			N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide	Not in list	C9H14N2O3S	O=S(=O)(Nc1ccc(cc1)CO)N(C)C	InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST			N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide	Not in list	C9H14N2O3S	O=S(=O)(Nc1ccc(cc1)CO)N(C)C	InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST			N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide	Not in list	C9H14N2O3S	O=S(=O)(Nc1ccc(cc1)CO)N(C)C	InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST			N'-[4-(hydroxymethyl)phenyl]-N,N-dimethylsulfamide	Not in list	C9H14N2O3S	O=S(=O)(Nc1ccc(cc1)CO)N(C)C	InChI=1/C9H14N2O3S/c1-11(2)15(13,14)10-9-5-3-8(7-12)4-6-9/h3-6,10,12H,7H2,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	4-Hydroxymethyl-DMST-glucoside			N,N-dimethyl-N´-[(4-(ß-D-glucopyranosyl)-methylphenyl]sulfamide	Not in list	C16H26N2O8S	CN(C)S(=O)(=O)Nc2ccc(CO[C@H]1C[C@H](O)[C@H](O)[C@H](O)[C@@H](CO)O1)cc2	InChI=1/C16H26N2O8S/c1-18(2)27(23,24)17-11-5-3-10(4-6-11)9-25-14-7-12(20)15(21)16(22)13(8-19)26-14/h3-6,12-17,19-22H,7-9H2,1-2H3/t12-,13+,14+,15-,16+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST-glucoside			N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide	Not in list	C15H24N2O8S	CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O	InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST-glucoside			N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide	Not in list	C15H24N2O8S	CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O	InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST-glucoside			N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide	Not in list	C15H24N2O8S	CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O	InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST-glucoside			N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide	Not in list	C15H24N2O8S	CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O	InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST-glucoside			N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide	Not in list	C15H24N2O8S	CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O	InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST-glucoside			N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide	Not in list	C15H24N2O8S	CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O	InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST-glucoside			N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide	Not in list	C15H24N2O8S	CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O	InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST-glucoside			N,N-dimethyl-N´-[[2-(ß-D-glucopyranosyl)-4-methyl]phenyl]sulfamide	Not in list	C15H24N2O8S	CN(C)S(=O)(=O)Nc2ccc(C)cc2OC1OC(CO)C(O)C(O)C1O	InChI=1/C15H24N2O8S/c1-8-4-5-9(16-26(22,23)17(2)3)10(6-8)24-15-14(21)13(20)12(19)11(7-18)25-15/h4-6,11-16,18-21H,7H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST			N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide	Not in list	C9H14N2O3S	Oc1cc(C)ccc1NS(=O)(=O)N(C)C	InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST			N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide	Not in list	C9H14N2O3S	Oc1cc(C)ccc1NS(=O)(=O)N(C)C	InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST			N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide	Not in list	C9H14N2O3S	Oc1cc(C)ccc1NS(=O)(=O)N(C)C	InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST			N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide	Not in list	C9H14N2O3S	Oc1cc(C)ccc1NS(=O)(=O)N(C)C	InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST			N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide	Not in list	C9H14N2O3S	Oc1cc(C)ccc1NS(=O)(=O)N(C)C	InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST			N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide	Not in list	C9H14N2O3S	Oc1cc(C)ccc1NS(=O)(=O)N(C)C	InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST			N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide	Not in list	C9H14N2O3S	Oc1cc(C)ccc1NS(=O)(=O)N(C)C	InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST			N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide	Not in list	C9H14N2O3S	Oc1cc(C)ccc1NS(=O)(=O)N(C)C	InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST			N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide	Not in list	C9H14N2O3S	Oc1cc(C)ccc1NS(=O)(=O)N(C)C	InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is a metabolite of the substance	2-Hydroxyphenyl-DMST			N,N-dimethyl-N´-[(2-hydroxy-4-methyl)-phenyl]sulfamide	Not in list	C9H14N2O3S	Oc1cc(C)ccc1NS(=O)(=O)N(C)C	InChI=1/C9H14N2O3S/c1-7-4-5-8(9(12)6-7)10-15(13,14)11(2)3/h4-6,10,12H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Finland	Tolylfluanid	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiromesifen		283594-90-1	single chemical entity	Component is identical to the substance	Spiromesifen		283594-90-1	2-oxo-3-(2,4,6-trimethylphenyl)-1-oxaspiro[4.4]non-3-en-4-yl 3,3-dimethylbutanoate	Spiromesifen	C23H30O4	O=C(CC(C)(C)C)OC1=C(C3=C(C)C=C(C)C=C3C)C(OC21CCCC2)=O	InChI=1S/C23H30O4/c1-14-11-15(2)18(16(3)12-14)19-20(26-17(24)13-22(4,5)6)23(27-21(19)25)9-7-8-10-23/h11-12H,7-10,13H2,1-6H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Spiromesifen	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiromesifen	12Oct2012	2012	doi:10.2903/j.efsa.2012.2879
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is identical to the substance	Spiroxamine		118134-30-8	N-[(8-tert-butyl-1,4-dioxaspiro[4.5]decan-3-yl)methyl]-N-ethylpropan-1-amine	Spiroxamine (sum of isomers)	C18H35NO2	CCCN(CC)CC1COC2(O1)CCC(CC2)C(C)(C)C	InChI=1S/C18H35NO2/c1-6-12-19(7-2)13-16-14-20-18(21-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Spiroxamine		118134-30-8	single chemical entity	Component is a metabolite of the substance	[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide			[(8-tert-butyl-1,4-dioxaspiro[4.5]dec-2-yl)methyl]ethyl(propyl)amine oxide	Not in list	C18H35NO3	CC(C)(C)C1CCC2(CC1)OCC(C[N+]([O-])(CC)CCC)O2	InChI=1/C18H35NO3/c1-6-12-19(20,7-2)13-16-14-21-18(22-16)10-8-15(9-11-18)17(3,4)5/h15-16H,6-14H2,1-5H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Spiroxamine	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spiroxamine.	22Oct2010	2010	doi:10.2903/j.efsa.2010.1719
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male/Female	intraperitoneal	16.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Fenhexamid	422-530-5	126833-17-8	single chemical entity	Component is identical to the substance	Fenhexamid	422-530-5	126833-17-8	N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide	Fenhexamid	C14H17Cl2NO2	CC1(CCCCC1)C(=O)NC2=C(C(=C(C=C2)O)Cl)Cl	InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: The United Kingdom	Fenhexamid (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenhexamid	07Jul2014	2014	doi:10.2903/j.efsa.2014.3744
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Positive			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	6	Male	intraperitoneal	48.0000000000	h	yes	not applicable	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	6	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: unspecified	4.0000000000	h	no	not applicable	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is identical to the substance	Spirotetramat		203313-25-1	[3-(2,5-dimethylphenyl)-8-methoxy-2-oxo-1-azaspiro[4.5]dec-3-en-4-yl] ethyl carbonate	Not in list	C21H27NO5	CCOC(=O)OC1=C(C(=O)NC12CCC(CC2)OC)C3=C(C=CC(=C3)C)C	InChI=1S/C21H27NO5/c1-5-26-20(24)27-18-17(16-12-13(2)6-7-14(16)3)19(23)22-21(18)10-8-15(25-4)9-11-21/h6-7,12,15H,5,8-11H2,1-4H3,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: unspecified	16.0000000000	h	no	not applicable	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C18H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O	InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C18H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O	InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C18H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O	InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C18H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O	InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C18H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O	InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C18H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O	InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C18H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O	InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C18H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O	InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C18H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O	InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3-hydroxy-8-methoxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C18H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(CC2)OC)NC3=O	InChI=1/C18H23NO4/c1-11-4-5-12(2)14(10-11)18(22)15(20)17(19-16(18)21)8-6-13(23-3)7-9-17/h4-5,10,13,22H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C17H21NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O	InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C17H21NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O	InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C17H21NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O	InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C17H21NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O	InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C17H21NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O	InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C17H21NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O	InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C17H21NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O	InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C17H21NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O	InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C17H21NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O	InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione			3-(2,5-dimethylphenyl)-3,8-dihydroxy-1-azaspiro[4.5]decane-2,4-dione	Not in list	C17H21NO4	Cc1cc(c(C)cc1)C3(O)C(=O)C2(CCC(O)CC2)NC3=O	InChI=1/C17H21NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,19,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one	Not in list	C17H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O	InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one	Not in list	C17H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O	InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one	Not in list	C17H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O	InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one	Not in list	C17H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O	InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one	Not in list	C17H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O	InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one	Not in list	C17H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O	InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one	Not in list	C17H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O	InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one	Not in list	C17H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O	InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one	Not in list	C17H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O	InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-3,4,8-trihydroxy-1-azaspiro[4.5]decan-2-one	Not in list	C17H23NO4	Cc1cc(c(C)cc1)C3(O)C(=O)NC2(CCC(O)CC2)C3O	InChI=1/C17H23NO4/c1-10-3-4-11(2)13(9-10)17(22)14(20)16(18-15(17)21)7-5-12(19)6-8-16/h3-4,9,12,14,19-20,22H,5-8H2,1-2H3,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one	Not in list	C18H25NO3	Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3	InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one	Not in list	C18H25NO3	Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3	InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one	Not in list	C18H25NO3	Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3	InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one	Not in list	C18H25NO3	Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3	InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one	Not in list	C18H25NO3	Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3	InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one	Not in list	C18H25NO3	Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3	InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one	Not in list	C18H25NO3	Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3	InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one	Not in list	C18H25NO3	Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3	InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one	Not in list	C18H25NO3	Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3	InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Spirotetramat		203313-25-1	single chemical entity	Component is a metabolite of the substance	(5s,8s)-3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one			3-(2,5-dimethylphenyl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]decan-2-one	Not in list	C18H25NO3	Cc3cc(C2C(=O)NC1(CCC(CC1)OC)C2O)c(C)cc3	InChI=1/C18H25NO3/c1-11-4-5-12(2)14(10-11)15-16(20)18(19-17(15)21)8-6-13(22-3)7-9-18/h4-5,10,13,15-16,20H,6-9H2,1-3H3,(H,19,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Spirotetramat	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance spirotetramat.	07Jun2013	2013	doi:10.2903/j.efsa.2013.3243
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is identical to the substance	Fluazinam		79622-59-6	3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine	Fluazinam	C13H4Cl2F6N4O4	C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F	InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Positive			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine			3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine	Not in list	C13H6Cl2F6N4O2	[O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F	InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine			3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine	Not in list	C13H6Cl2F6N4O2	[O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F	InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine			3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine	Not in list	C13H6Cl2F6N4O2	[O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F	InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine			3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine	Not in list	C13H6Cl2F6N4O2	[O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F	InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine			3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine	Not in list	C13H6Cl2F6N4O2	[O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F	InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine			3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine	Not in list	C13H6Cl2F6N4O2	[O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F	InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine			3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine	Not in list	C13H6Cl2F6N4O2	[O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F	InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine			3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine	Not in list	C13H6Cl2F6N4O2	[O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F	InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine			3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine	Not in list	C13H6Cl2F6N4O2	[O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F	InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	2-chloro-6-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-5-nitro-m-toluidine			3-chloro-N1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-6-nitro-4-(trifluoromethyl)benzene-1,2-diamine	Not in list	C13H6Cl2F6N4O2	[O-][N+](=O)c2cc(c(Cl)c(N)c2Nc1ncc(cc1Cl)C(F)(F)F)C(F)(F)F	InChI=1/C13H6Cl2F6N4O2/c14-6-1-4(12(16,17)18)3-23-11(6)24-10-7(25(26)27)2-5(13(19,20)21)8(15)9(10)22/h1-3H,22H2,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	6	Male	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	6	Male	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	6	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	6	Male	oral: gavage	16.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	6	Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	6	Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	6	Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fluazinam		79622-59-6	single chemical entity	Component is a metabolite of the substance	5-(3-chloro-5-trifluoromethyl-2-pyridylamino)-α,α,α-trifluoro-4,6-dinitro-o-cresol			3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-2,4-dinitro-6-(trifluoromethyl)phenol	Not in list	C13H5ClF6N4O5	[O-][N+](=O)c2cc(c(O)c(c2Nc1ncc(cc1Cl)C(F)(F)F)[N+]([O-])=O)C(F)(F)F	InChI=1/C13H5ClF6N4O5/c14-6-1-4(12(15,16)17)3-21-11(6)22-8-7(23(26)27)2-5(13(18,19)20)10(25)9(8)24(28)29/h1-3,25H,(H,21,22)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	6	Female	oral: gavage	16.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fluazinam	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluazinam	29Jul2008	2008	doi:10.2903/j.efsa.2008.137r
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	large colonies		RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	small colonies		RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	5	Male	oral: unspecified	18.0000000000	h	yes	not applicable	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is identical to the substance	Fenamidone	605-252-0	161326-34-7	(S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one	Fenamidone	C17H17N3OS	CC1(C(=O)N(C(=N1)SC)NC2=CC=CC=C2)C3=CC=CC=C3	InChI=1S/C17H17N3OS/c1-17(13-9-5-3-6-10-13)15(21)20(16(18-17)22-2)19-14-11-7-4-8-12-14/h3-12,19H,1-2H3/t17-/m0/s1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	5	Male	oral: unspecified	4.0000000000	h	yes	not applicable	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-5-phenylimidazolidine-2,4-dione			(5S)-5-methyl-5-phenylimidazolidine-2,4-dione	Not in list	C10H10N2O2	C[C@]1(NC(=O)NC1=O)c2ccccc2	InChI=1/C10H10N2O2/c1-10(7-5-3-2-4-6-7)8(13)11-9(14)12-10/h2-6H,1H3,(H2,11,12,13,14)/t10-/m0/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	8	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(S)-5-Methyl-5-phenyl-3-(phenylamino)- 2,4-imidazolidine-dione			(5S)-5-methyl-5-phenyl-3-(phenylamino)imidazolidine-2,4-dione	Not in list	C16H15N3O2	O=C2N(Nc1ccccc1)C(=O)N[C@@]2(C)c3ccccc3	InChI=1/C16H15N3O2/c1-16(12-8-4-2-5-9-12)14(20)19(15(21)17-16)18-13-10-6-3-7-11-13/h2-11,18H,1H3,(H,17,21)/t16-/m0/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	8	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	8	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenoxycarb	276-696-7	72490-01-8	single chemical entity	Component is identical to the substance	Fenoxycarb	276-696-7	72490-01-8	ethyl [2-(4-phenoxyphenoxy)ethyl]carbamate	Fenoxycarb	C17H19NO4	O=C(NCCOC1=CC=C(OC2=CC=CC=C2)C=C1)OCC	InChI=1S/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: unspecified		h	yes	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The Netherlands	Fenoxycarb (Final Addendum)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenoxycarb	14Dec2010	2010	doi:10.2903/j.efsa.2010.1779
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	NMRI	50	Male	oral: unspecified	20.0000000000	D	no data	not applicable	Negative			RMS: The Netherlands	Fenamiphos	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	5	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	5	Male/Female	intraperitoneal	16.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is identical to the substance	Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	ethyl 3-methyl-4-(methylthio)phenyl isopropylamidophosphate	Fenamiphos	C13H22NO3PS	Cc1cc(ccc1SC)OP(=O)(NC(C)C)OCC	InChI=1S/C13H22NO3PS/c1-6-16-18(15,14-10(2)3)17-12-7-8-13(19-5)11(4)9-12/h7-10H,6H2,1-5H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	5	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is a metabolite of the substance	des-isopropylamino fenamiphos sulfoxide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is a metabolite of the substance	des-isopropylamino fenamiphos sulfoxide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is a metabolite of the substance	des-isopropylamino fenamiphos sulfoxide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is a metabolite of the substance	des-isopropylamino fenamiphos sulfoxide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is a metabolite of the substance	des-isopropylamino fenamiphos sulfoxide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is a metabolite of the substance	des-isopropylamino fenamiphos sulfoxide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is a metabolite of the substance	des-isopropylamino fenamiphos sulfoxide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is a metabolite of the substance	des-isopropylamino fenamiphos sulfoxide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is a metabolite of the substance	des-isopropylamino fenamiphos sulfoxide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenamiphos (aka phenamiphos)	244-848-1	22224-92-6	single chemical entity	Component is a metabolite of the substance	des-isopropylamino fenamiphos sulfoxide				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The Netherlands	Fenamiphos (Final Addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenamiphos	07Mar2006	2006	doi:10.2903/j.efsa.2006.62r
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Alpha 742 S. marcescens			Not reported			yes	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Alpha 21 S. marcescens			Not reported			yes	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Other	Alpha 13 S. marcescens			Not reported			yes	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	6	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CF-1	4	Male/Female	intraperitoneal	8.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	CF-1	4	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenbutatin oxide	236-407-7	13356-08-6	single chemical entity	Component is identical to the substance	Fenbutatin oxide	236-407-7	13356-08-6	hexakis(2-methyl-2-phenylpropyl)distannoxane	Fenbutatin oxide	C60H78OSn2	CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c2ccccc2)O[Sn](CC(C)(C)c3ccccc3)(CC(C)(C)c4ccccc4)CC(C)(C)c5ccccc5)c6ccccc6	InChI=1/6C10H13.O.2Sn/c6*1-10(2,3)9-7-5-4-6-8-9;;;/h6*4-8H,1H2,2-3H3;;;/rC60H78OSn2/c1-55(2,49-31-19-13-20-32-49)43-62(44-56(3,4)50-33-21-14-22-34-50,45-57(5,6)51-35-23-15-24-36-51)61-63(46-58(7,8)52-37-25-16-26-38-52,47-59(9,10)53-39-27-17-28-40-53)48-60	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	CF-1	8	Male	oral: gavage	7.0000000000	D	yes	not applicable	Negative			RMS: Belgium	Fenbutatin oxide	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbutatin oxide.	01Sep2010	2010	doi:10.2903/j.efsa.2010.1711
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	W3102 E.coli			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	no data	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	G46			Not reported			yes, concurrent vehicle	no data	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	W3102 E.coli			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	no data	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Positive			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	House mouse (as animal)	Not reported			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	House mouse (as animal)	Not reported			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	6	Male	oral: unspecified	6.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	6	Male	oral: unspecified	48.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	6	Male	oral: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	ICR	6	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	3	Male	Not reported	24.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	3	Male	Not reported	12.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	3	Male	Not reported	3.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	ICR	12	Male	oral: gavage	5.0000000000	D	yes	not applicable	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenitrothion	204-524-2	122-14-5	single chemical entity	Component is identical to the substance	Fenitrothion	204-524-2	122-14-5	O,O-dimethyl O-(3-methyl-4-nitrophenyl) thiophosphate	Fenitrothion	C9H12NO5PS	COP(=S)(OC)Oc1ccc(c(C)c1)[N+](=O)[O-]	InChI=1/C9H12NO5PS/c1-7-6-8(4-5-9(7)10(11)12)15-16(17,13-2)14-3/h4-6H,1-3H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	11	Male	oral: gavage	5.0000000000	D	yes	not applicable	Negative			RMS: The United Kingdom	Fenitrothion	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenitrothion	22Feb2006	2006	doi:10.2903/j.efsa.2006.59r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Ambiguous			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	gene mutation	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Fenpropimorph	266-719-9	67564-91-4	single chemical entity	Component is identical to the substance	Fenpropimorph	266-719-9	67564-91-4	(2R,6S)-4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine	Fenpropimorph	C20H33NO	CC(C)(C)C(C=C2)=CC=C2CC(C)CN1C[C@@H](C)O[C@@H](C)C1	InChI=1S/C20H33NO/c1-15(12-21-13-16(2)22-17(3)14-21)11-18-7-9-19(10-8-18)20(4,5)6/h7-10,15-17H,11-14H2,1-6H3/t15?,16-,17+	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	NMRI	40	Male	intraperitoneal	18.0000000000	D	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Fenpropimorph	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropimorph	29Jul2008	2008	doi:10.2903/j.efsa.2008.144r
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is identical to the substance	Flubendiamide		272451-65-7	3-iodo-N'-(2-mesyl-1,1-dimethylethyl)-N-(4-(1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl)-o-tolyl)phthalamide	Flubendiamide	C23H22F7IN2O4S	CC1=C(C=CC(=C1)C(C(F)(F)F)(C(F)(F)F)F)NC(=O)C2=C(C(=CC=C2)I)C(=O)NC(C)(C)CS(=O)(=O)C	InChI=1S/C23H22F7IN2O4S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-16(12)32-18(34)14-6-5-7-15(31)17(14)19(35)33-20(2,3)11-38(4,36)37/h5-10H,11H2,1-4H3,(H,32,34)(H,33,35)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity$indirect evidence-systemic toxicity	RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O4S	Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O4S	Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O4S	Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O4S	Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O4S	Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O4S	Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O4S	Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O4S	Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O4S	Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-N'-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O4S	Cc2cc(ccc2NC(=O)c1ccccc1C(=O)NC(C)(C)CS(C)(=O)=O)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O4S/c1-13-11-14(21(24,22(25,26)27)23(28,29)30)9-10-17(13)31-18(33)15-7-5-6-8-16(15)19(34)32-20(2,3)12-37(4,35)36/h5-11H,12H2,1-4H3,(H,31,33)(H,32,34)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O5S	O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O5S	O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O5S	O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O5S	O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O5S	O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O5S	O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O5S	O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O5S	O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O5S	O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flubendiamide		272451-65-7	single chemical entity	Component is a metabolite of the substance	N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide			N-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylphenyl]-3-hydroxy-N2-[2-methyl-1-(methylsulfonyl)propan-2-yl]phthalamide	Not in list	C23H23F7N2O5S	O=C(NC(C)(C)CS(C)(=O)=O)c1c(cccc1O)C(=O)Nc2ccc(cc2C)C(F)(C(F)(F)F)C(F)(F)F	InChI=1/C23H23F7N2O5S/c1-12-10-13(21(24,22(25,26)27)23(28,29)30)8-9-15(12)31-18(34)14-6-5-7-16(33)17(14)19(35)32-20(2,3)11-38(4,36)37/h5-10,33H,11H2,1-4H3,(H,31,34)(H,32,35)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Greece	Flubendiamide	2008	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flubendiamide.	09Sep2013	2013	doi:10.2903/j.efsa.2013.3298
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	14.0000000000	h	yes	not applicable	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	House mouse (as animal)	ddy mouse	3	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	House mouse (as animal)	ddy mouse	3	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	House mouse (as animal)	ddy mouse	3	Male	oral: unspecified	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	House mouse (as animal)	ddy mouse	3	Male	oral: unspecified	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	House mouse (as animal)	ddy mouse	3	Male	oral: unspecified	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is identical to the substance	Flonicamid		158062-67-0	N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Flonicamid	C9H6F3N3O	O=C(NCC#N)c1cnccc1C(F)(F)F	InChI=1S/C9H6F3N3O/c10-9(11,12)7-1-3-14-5-6(7)8(16)15-4-2-13/h1,3,5H,4H2,(H,15,16)	organic	compound	Other	Other	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	According to	OECD Guideline 489	No	Acceptable	House mouse (as animal)	ddy mouse	3	Male	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinic acid	623-902-1	158063-66-2	4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO2	C1=CN=CC(=C1C(F)(F)F)C(=O)O	InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinic acid	623-902-1	158063-66-2	4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO2	C1=CN=CC(=C1C(F)(F)F)C(=O)O	InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinic acid	623-902-1	158063-66-2	4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO2	C1=CN=CC(=C1C(F)(F)F)C(=O)O	InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinic acid	623-902-1	158063-66-2	4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO2	C1=CN=CC(=C1C(F)(F)F)C(=O)O	InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinic acid	623-902-1	158063-66-2	4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO2	C1=CN=CC(=C1C(F)(F)F)C(=O)O	InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinic acid	623-902-1	158063-66-2	4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO2	C1=CN=CC(=C1C(F)(F)F)C(=O)O	InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinic acid	623-902-1	158063-66-2	4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO2	C1=CN=CC(=C1C(F)(F)F)C(=O)O	InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinic acid	623-902-1	158063-66-2	4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO2	C1=CN=CC(=C1C(F)(F)F)C(=O)O	InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinic acid	623-902-1	158063-66-2	4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO2	C1=CN=CC(=C1C(F)(F)F)C(=O)O	InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinic acid	623-902-1	158063-66-2	4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO2	C1=CN=CC(=C1C(F)(F)F)C(=O)O	InChI=1S/C7H4F3NO2/c8-7(9,10)5-1-2-11-3-4(5)6(12)13/h1-3H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinamide			4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C7H5F3N2O	C1=CN=CC(=C1C(F)(F)F)C(=O)N	InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinamide			4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C7H5F3N2O	C1=CN=CC(=C1C(F)(F)F)C(=O)N	InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinamide			4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C7H5F3N2O	C1=CN=CC(=C1C(F)(F)F)C(=O)N	InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinamide			4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C7H5F3N2O	C1=CN=CC(=C1C(F)(F)F)C(=O)N	InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinamide			4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C7H5F3N2O	C1=CN=CC(=C1C(F)(F)F)C(=O)N	InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinamide			4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C7H5F3N2O	C1=CN=CC(=C1C(F)(F)F)C(=O)N	InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinamide			4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C7H5F3N2O	C1=CN=CC(=C1C(F)(F)F)C(=O)N	InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinamide			4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C7H5F3N2O	C1=CN=CC(=C1C(F)(F)F)C(=O)N	InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinamide			4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C7H5F3N2O	C1=CN=CC(=C1C(F)(F)F)C(=O)N	InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	4-trifluoromethylnicotinamide			4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C7H5F3N2O	C1=CN=CC(=C1C(F)(F)F)C(=O)N	InChI=1S/C7H5F3N2O/c8-7(9,10)5-1-2-12-3-4(5)6(11)13/h1-3H,(H2,11,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycine			N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine	Not in list	C9H7F3N2O3	C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O	InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycine			N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine	Not in list	C9H7F3N2O3	C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O	InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycine			N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine	Not in list	C9H7F3N2O3	C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O	InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycine			N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine	Not in list	C9H7F3N2O3	C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O	InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycine			N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine	Not in list	C9H7F3N2O3	C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O	InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycine			N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine	Not in list	C9H7F3N2O3	C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O	InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycine			N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine	Not in list	C9H7F3N2O3	C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O	InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycine			N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine	Not in list	C9H7F3N2O3	C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O	InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycine			N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine	Not in list	C9H7F3N2O3	C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O	InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycine			N-{[4-(trifluoromethyl)pyridin-3-yl]carbonyl}glycine	Not in list	C9H7F3N2O3	C1=CN=CC(=C1C(F)(F)F)C(=O)NCC(=O)O	InChI=1S/C9H7F3N2O3/c10-9(11,12)6-1-2-13-3-5(6)8(17)14-4-7(15)16/h1-3H,4H2,(H,14,17)(H,15,16)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycinamide			N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C9H8F3N3O2	O=C(NCC(N)=O)c1cnccc1C(F)(F)F	InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycinamide			N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C9H8F3N3O2	O=C(NCC(N)=O)c1cnccc1C(F)(F)F	InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycinamide			N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C9H8F3N3O2	O=C(NCC(N)=O)c1cnccc1C(F)(F)F	InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycinamide			N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C9H8F3N3O2	O=C(NCC(N)=O)c1cnccc1C(F)(F)F	InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycinamide			N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C9H8F3N3O2	O=C(NCC(N)=O)c1cnccc1C(F)(F)F	InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycinamide			N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C9H8F3N3O2	O=C(NCC(N)=O)c1cnccc1C(F)(F)F	InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycinamide			N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C9H8F3N3O2	O=C(NCC(N)=O)c1cnccc1C(F)(F)F	InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycinamide			N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C9H8F3N3O2	O=C(NCC(N)=O)c1cnccc1C(F)(F)F	InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycinamide			N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C9H8F3N3O2	O=C(NCC(N)=O)c1cnccc1C(F)(F)F	InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	N-(4-trifluoromethylnicotinoyl)glycinamide			N-(2-amino-2-oxoethyl)-4-(trifluoromethyl)pyridine-3-carboxamide	Not in list	C9H8F3N3O2	O=C(NCC(N)=O)c1cnccc1C(F)(F)F	InChI=1/C9H8F3N3O2/c10-9(11,12)6-1-2-14-3-5(6)8(17)15-4-7(13)16/h1-3H,4H2,(H2,13,16)(H,15,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	6-hydroxy-4-trifluoromethylnicotinic acid			6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO3	FC(F)(F)c1cc(O)ncc1C(O)=O	InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	6-hydroxy-4-trifluoromethylnicotinic acid			6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO3	FC(F)(F)c1cc(O)ncc1C(O)=O	InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	6-hydroxy-4-trifluoromethylnicotinic acid			6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO3	FC(F)(F)c1cc(O)ncc1C(O)=O	InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	6-hydroxy-4-trifluoromethylnicotinic acid			6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO3	FC(F)(F)c1cc(O)ncc1C(O)=O	InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	6-hydroxy-4-trifluoromethylnicotinic acid			6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO3	FC(F)(F)c1cc(O)ncc1C(O)=O	InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	6-hydroxy-4-trifluoromethylnicotinic acid			6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO3	FC(F)(F)c1cc(O)ncc1C(O)=O	InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	6-hydroxy-4-trifluoromethylnicotinic acid			6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO3	FC(F)(F)c1cc(O)ncc1C(O)=O	InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	6-hydroxy-4-trifluoromethylnicotinic acid			6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO3	FC(F)(F)c1cc(O)ncc1C(O)=O	InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	6-hydroxy-4-trifluoromethylnicotinic acid			6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO3	FC(F)(F)c1cc(O)ncc1C(O)=O	InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Flonicamid	605-127-0	158062-67-0	single chemical entity	Component is a metabolite of the substance	6-hydroxy-4-trifluoromethylnicotinic acid			6-hydroxy-4-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H4F3NO3	FC(F)(F)c1cc(O)ncc1C(O)=O	InChI=1/C7H4F3NO3/c8-7(9,10)4-1-5(12)11-2-3(4)6(13)14/h1-2H,(H,11,12)(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flonicamid	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flonicamid	07May2010	2010	doi:10.2903/j.efsa.2010.1445
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is identical to the substance	Fluoxastrobin	609-207-6	361377-29-9	(E)-1-[2-[6-(2-chlorophenoxy)-5-fluoropyrimidin-4-yl]oxyphenyl]-1-(5,6-dihydro-1,4,2-dioxazin-3-yl)-N-methoxymethanimine	Fluoxastrobin	Fluoxastrobin	CO/N=C(\C1=CC=CC=C1OC2=C(C(=NC=N2)OC3=CC=CC=C3Cl)F)/C4=NOCCO4	InChI=1S/C21H16ClFN4O5/c1-28-26-18(21-27-30-11-10-29-21)13-6-2-4-8-15(13)31-19-17(23)20(25-12-24-19)32-16-9-5-3-7-14(16)22/h2-9,12H,10-11H2,1H3/b26-18+	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		indirect evidence-systemic toxicity	RMS: The United Kingdom	Fluoxastrobin	2003	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is a metabolite of the substance	HEC5725-E-des-chlorophenyl			(E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime	Not in list	C15H13FN4O5	Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1	InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is a metabolite of the substance	HEC5725-E-des-chlorophenyl			(E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime	Not in list	C15H13FN4O5	Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1	InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is a metabolite of the substance	HEC5725-E-des-chlorophenyl			(E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime	Not in list	C15H13FN4O5	Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1	InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is a metabolite of the substance	HEC5725-E-des-chlorophenyl			(E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime	Not in list	C15H13FN4O5	Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1	InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is a metabolite of the substance	HEC5725-E-des-chlorophenyl			(E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime	Not in list	C15H13FN4O5	Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1	InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is a metabolite of the substance	HEC5725-E-des-chlorophenyl			(E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime	Not in list	C15H13FN4O5	Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1	InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is a metabolite of the substance	HEC5725-E-des-chlorophenyl			(E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime	Not in list	C15H13FN4O5	Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1	InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fluoxastrobin (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is a metabolite of the substance	HEC5725-E-des-chlorophenyl			(E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime	Not in list	C15H13FN4O5	Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1	InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is a metabolite of the substance	HEC5725-E-des-chlorophenyl			(E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime	Not in list	C15H13FN4O5	Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1	InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fluoxastrobin	609-207-6	361377-29-9	single chemical entity	Component is a metabolite of the substance	HEC5725-E-des-chlorophenyl			(E)-5,6-dihydro-1,4,2-dioxazin-3-yl{2-[(5-fluoro-6-hydroxypyrimidin-4-yl)oxy]phenyl}methanone O-methyloxime	Not in list	C15H13FN4O5	Fc3c(O)ncnc3Oc2ccccc2C(=N\OC)/C=1OCCON=1	InChI=1/C15H13FN4O5/c1-22-19-12(15-20-24-7-6-23-15)9-4-2-3-5-10(9)25-14-11(16)13(21)17-8-18-14/h2-5,8H,6-7H2,1H3,(H,17,18,21)/b19-12+	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fluoxastrobin (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fluoxastrobin	31Aug2005	2005	doi:10.2903/j.efsa.2005.102r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is identical to the substance	Fenpropidin		67306-00-7	1-[3-(4-Tert-butylphenyl)-2-methylpropyl]piperidine	Fenpropidin (sum of fenpropidin and its salts, expressed as fenpropidin)	C19H31N	CC(CC1=CC=C(C=C1)C(C)(C)C)CN2CCCCC2	InChI=1S/C19H31N/c1-16(15-20-12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Tif:MAGf(SPF)	10	Male/Female	oral: gavage	16.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Sweden	Fenpropidin	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fenpropidin		67306-00-7	single chemical entity	Component is a metabolite of the substance	1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide			1-[3-(4-tert-butyl-phenyl)-2-methyl-propyl]-piperidine-1-oxide	Not in list	C19H31NO	[O-][N+]2(CC(C)Cc1ccc(cc1)C(C)(C)C)CCCCC2	InChI=1/C19H31NO/c1-16(15-20(21)12-6-5-7-13-20)14-17-8-10-18(11-9-17)19(2,3)4/h8-11,16H,5-7,12-15H2,1-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Sweden	Fenpropidin (Addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenpropidin	30Jan2008	2008	doi:10.2903/j.efsa.2008.124r
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	3	Male	oral: gavage	14.0000000000	h	yes	not applicable	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is identical to the substance	Fluquinconazole	411-960-9	136426-54-5	3-(2,4-dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)quinazolin-4(3H)-one	Fluquinconazole	C16H8Cl2FN5O	Clc4ccc(N1C(=O)c3cc(F)ccc3N=C1n2cncn2)c(Cl)c4	InChI=1S/C16H8Cl2FN5O/c17-9-1-4-14(12(18)5-9)24-15(25)11-6-10(19)2-3-13(11)22-16(24)23-8-20-7-21-23/h1-8H	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	Equivalent or similar to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	Yes	Acceptable	Rat (as animal)	Crj:CD(SD)	3	Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Fluquinconazole	411-960-9	136426-54-5	single chemical entity	Component is a metabolite of the substance	3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione			3-(2,4-dichlorophenyl)-6-fluoro-2,4(1H,3H)-quinazolinedione	Not in list	C14H7Cl2FN2O2	Clc1ccc(c(Cl)c1)N2C(=O)c3cc(F)ccc3NC2=O	InChI=1S/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	30	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Ireland	Fluquinconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluquinconazole	11May2011	2011	doi:10.2903/j.efsa.2011.2096
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Positive			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR		No data	intraperitoneal			no data	not applicable	Negative		no evidence	RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley		No data	oral: gavage			no data	not applicable	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Flumioxazin		103361-09-7	single chemical entity	Component is identical to the substance	Flumioxazin		103361-09-7	N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzoxazin-6-yl)cyclohex-1-ene-1,2-dicarboxamide	Flumioxazine	C19H15FN2O4	C#CCN1C(=O)COC2=CC(=C(C=C21)N3C(=O)C4=C(C3=O)CCCC4)F	InChI=1S/C19H15FN2O4/c1-2-7-21-15-9-14(13(20)8-16(15)26-10-17(21)23)22-18(24)11-5-3-4-6-12(11)19(22)25/h1,8-9H,3-7,10H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley		No data	oral: unspecified			no data	not applicable	Negative			RMS: France	Flumioxazin  (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flumioxazin	12Jun2014	2014	doi:10.2903/j.efsa.2014.3736
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Inconclusive			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	10	Male/Female	oral: gavage	30.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	10	Male/Female	oral: gavage	18.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is identical to the substance	Quinmerac		90717-03-6	7-chloro-3-methylquinoline-8-carboxylic acid	Quinmerac	C11H8ClNO2	O=C(O)C1=C(Cl)C=CC2=C1N=CC(C)=C2	InChI=1S/C11H8ClNO2/c1-6-4-7-2-3-8(12)9(11(14)15)10(7)13-5-6/h2-5H,1H3,(H,14,15)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Inconclusive			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Inconclusive			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid			7-chloro-2-hydroxy-3-methylquinoline-8-carboxylic acid	Not in list	C11H8ClNO3	OC(=O)c1c(Cl)ccc2cc(C)c(O)nc12	InChI=1/C11H8ClNO3/c1-5-4-6-2-3-7(12)8(11(15)16)9(6)13-10(5)14/h2-4H,1H3,(H,13,14)(H,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Positive			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect-toxicokinetic investigations	RMS: The United Kingdom	Quinmerac	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Quinmerac		90717-03-6	single chemical entity	Component is a metabolite of the substance	7-chloroquinoline-3,8-dicarboxylic acid			7-chloroquinoline-3,8-dicarboxylic acid	Not in list	C11H6ClNO4	OC(=O)c1c(Cl)ccc2cc(cnc12)C(O)=O	InChI=1/C11H6ClNO4/c12-7-2-1-5-3-6(10(14)15)4-13-9(5)8(7)11(16)17/h1-4H,(H,14,15)(H,16,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The United Kingdom	Quinmerac (Additional report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance quinmerac	29Mar2010	2010	doi:10.2903/j.efsa.2010.1523
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is identical to the substance	Sulfoxaflor		946578-00-3	[methyl-oxo-[1-[6(trifluoromethyl)pyridin-3-yl]ethyl]-λ{6}-sulfanylidene]cyanamide	Not in list	C10H10F3N3OS	CC(C1=CN=C(C=C1)C(F)(F)F)S(=NC#N)(=O)C	InChI=1S/C10H10F3N3OS/c1-7(18(2,17)16-6-14)8-3-4-9(15-5-8)10(11,12)13/h3-5,7H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	12	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea			1-[methyl(oxido){(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethyl}-(RS)λ6-sulfanylidene]urea	Not in list	C10H12F3N3O2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=NC(N)=O	InChI=1/C10H12F3N3O2S/c1-6(19(2,18)16-9(14)17)7-3-4-8(15-5-7)10(11,12)13/h3-6H,1-2H3,(H2,14,17)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol			(1RS)-1-[6-(trifluoromethyl)-3-pyridinyl]ethanol	Not in list	C8H8F3NO	FC(F)(F)c1ccc(cn1)C(C)O	InChI=1/C8H8F3NO/c1-5(13)6-2-3-7(12-4-6)8(9,10)11/h2-5,13H,1H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-ethyl-2-(trifluoromethyl)pyridine			5-ethyl-2-(trifluoromethyl)pyridine	Not in list	C8H8F3N	FC(F)(F)c1ccc(CC)cn1	InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-ethyl-2-(trifluoromethyl)pyridine			5-ethyl-2-(trifluoromethyl)pyridine	Not in list	C8H8F3N	FC(F)(F)c1ccc(CC)cn1	InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-ethyl-2-(trifluoromethyl)pyridine			5-ethyl-2-(trifluoromethyl)pyridine	Not in list	C8H8F3N	FC(F)(F)c1ccc(CC)cn1	InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-ethyl-2-(trifluoromethyl)pyridine			5-ethyl-2-(trifluoromethyl)pyridine	Not in list	C8H8F3N	FC(F)(F)c1ccc(CC)cn1	InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-ethyl-2-(trifluoromethyl)pyridine			5-ethyl-2-(trifluoromethyl)pyridine	Not in list	C8H8F3N	FC(F)(F)c1ccc(CC)cn1	InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-ethyl-2-(trifluoromethyl)pyridine			5-ethyl-2-(trifluoromethyl)pyridine	Not in list	C8H8F3N	FC(F)(F)c1ccc(CC)cn1	InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-ethyl-2-(trifluoromethyl)pyridine			5-ethyl-2-(trifluoromethyl)pyridine	Not in list	C8H8F3N	FC(F)(F)c1ccc(CC)cn1	InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-ethyl-2-(trifluoromethyl)pyridine			5-ethyl-2-(trifluoromethyl)pyridine	Not in list	C8H8F3N	FC(F)(F)c1ccc(CC)cn1	InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-ethyl-2-(trifluoromethyl)pyridine			5-ethyl-2-(trifluoromethyl)pyridine	Not in list	C8H8F3N	FC(F)(F)c1ccc(CC)cn1	InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-ethyl-2-(trifluoromethyl)pyridine			5-ethyl-2-(trifluoromethyl)pyridine	Not in list	C8H8F3N	FC(F)(F)c1ccc(CC)cn1	InChI=1/C8H8F3N/c1-2-6-3-4-7(12-5-6)8(9,10)11/h3-5H,2H2,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(S-methylsulfonimidoyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H11F3N2OS	FC(F)(F)c1ccc(cn1)C(C)S(C)(=N)=O	InChI=1/C9H11F3N2OS/c1-6(16(2,13)15)7-3-4-8(14-5-7)9(10,11)12/h3-6,13H,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Sulfoxaflor		946578-00-3	single chemical entity	Component is a metabolite of the substance	5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine			5-[(1RS)-1-(methylsulfonyl)ethyl]-2-(trifluoromethyl)pyridine	Not in list	C9H10F3NO2S	FC(F)(F)c1ccc(cn1)C(C)S(C)(=O)=O	InChI=1/C9H10F3NO2S/c1-6(16(2,14)15)7-3-4-8(13-5-7)9(10,11)12/h3-6H,1-2H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Ireland	Sulfoxaflor	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sulfoxaflor	21May2014	2014	doi:10.2903/j.efsa.2014.3692
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	fibroblast			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	Not reported			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Spain	Flurochloridone	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Flurochloridone	262-661-3	61213-25-0	single chemical entity	Component is identical to the substance	Flurochloridone	262-661-3	61213-25-0	3-chloro-4-(chloromethyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one	Flurochloridone	C12H10Cl2F3NO	C1C(C(C(=O)N1C2=CC=CC(=C2)C(F)(F)F)Cl)CCl	InChI=1S/C12H10Cl2F3NO/c13-5-7-6-18(11(19)10(7)14)9-3-1-2-8(4-9)12(15,16)17/h1-4,7,10H,5-6H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Flurochloridone (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active Substance Flurochloridone (notified active substance) (However this ISO name refers to a 3:1 ratio of trans to cis isomers. As the compound considered in this conclusion is not a	14Dec2010	2010	doi:10.2903/j.efsa.2010.1869
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity	RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: gavage	14.0000000000	h	yes	not applicable	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	ICR	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	ICR	5	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	No guideline followed	Not reported	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	No guideline followed	Not reported	No data	Acceptable	Saccharomyces cerevisiae (as organism)	D3			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Formetanate hydrochloride	245-656-0	23422-53-9	single chemical entity	Component is identical to the substance	Formetanate hydrochloride	245-656-0	23422-53-9	[3-(Dimethylaminomethylideneamino)phenyl] N-methylcarbamate;hydrochloride	Formetanate hydrochloride	C11H16ClN3O2	CNC(=O)OC1=CC=CC(=C1)N=CN(C)C.Cl	InChI=1S/C11H15N3O2.ClH/c1-12-11(15)16-10-6-4-5-9(7-10)13-8-14(2)3;/h4-8H,1-3H3,(H,12,15);1H	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Italy	Formetanate	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance formetanate	13Jun2006	2006	doi:10.2903/j.efsa.2006.69r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Positive			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	with	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	NMRI	20	Male	oral: unspecified	8.0000000000	week	no data	not applicable	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	oral: unspecified	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	intraperitoneal	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	intraperitoneal	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	intraperitoneal			yes	not applicable	Negative			RMS: The United Kingdom	Fuberidazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Positive			RMS: The United Kingdom	Fuberidazole (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	Equivalent or similar to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: The United Kingdom	Fuberidazole (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Not reported	6	Male	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fuberidazole (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fuberidazole	223-404-0	3878-19-1	single chemical entity	Component is identical to the substance	Fuberidazole	223-404-0	3878-19-1	2-(2-furyl)-1H-benzimidazole	Fuberidazole	C11H8N2O	o1cccc1c2nc3ccccc3[nH]2	InChI=1/C11H8N2O/c1-2-5-9-8(4-1)12-11(13-9)10-6-3-7-14-10/h1-7H,(H,12,13)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Not reported	6	Male	oral: gavage	42.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: The United Kingdom	Fuberidazole (Final addendum)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fuberidazole	09Jan2008	2008	doi:10.2903/j.efsa.2008.118r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Schizosaccharomyces pombe (as organism)	Not reported			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Schizosaccharomyces pombe (as organism)	Not reported			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			yes	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Human (as organism)	alveolar basal epithelial cells (A549)			Not reported			yes	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is identical to the substance	Fenoxaprop-P-ethyl		71283-80-2	Ethyl (2R)-2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-P-Ethyl	C18H16ClNO5	CCOC(=O)[C@@H](C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3/t11-/m1/s1	organic	compound	PubChem isomeric SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Schizosaccharomyces pombe (as organism)	Not reported			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Schizosaccharomyces pombe (as organism)	Not reported			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D4			Not reported			yes	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	HeLa cells			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fenoxaprop-P-ethyl		71283-80-2	single chemical entity	Component is part of a group assessment	Fenoxaprop-ethyl	266-362-9	66441-23-4	Ethyl 2-[4-[(6-chloro-1,3-benzoxazol-2-yl)oxy]phenoxy]propanoate	Fenoxaprop-ethyl	C18H16ClNO5	CCOC(=O)C(C)OC1=CC=C(C=C1)OC2=NC3=C(O2)C=C(C=C3)Cl	InChI=1S/C18H16ClNO5/c1-3-22-17(21)11(2)23-13-5-7-14(8-6-13)24-18-20-15-9-4-12(19)10-16(15)25-18/h4-11H,3H2,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Austria	Fenoxaprop-P-ethyl	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance fenoxaprop-P	13Dec2007	2007	doi:10.2903/j.efsa.2007.121r
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Positive	no information		RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Positive	no information		RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes	without	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Human (as organism)	fibroblast			Not reported			yes	with	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Fluroxypyr-meptyl	279-752-9	81406-37-3	single chemical entity	Component is identical to the substance	Fluroxypyr-meptyl	279-752-9	81406-37-3	Octan-2-yl 2-(4-amino-3,5-dichloro-6-fluoropyridin-2-yl)oxyacetate	Fluroxypyr-Meptyl	C15H21Cl2FN2O3	CCCCCCC(C)OC(=O)COC1=NC(=C(C(=C1Cl)N)Cl)F	InChI=1S/C15H21Cl2FN2O3/c1-3-4-5-6-7-9(2)23-10(21)8-22-15-12(17)13(19)11(16)14(18)20-15/h9H,3-8H2,1-2H3,(H2,19,20)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	Chinese	10	Male/Female	oral: gavage	6.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Fluroxypyr	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluroxypyr (evaluated variant fluroxypyr-meptyl)	08Mar2011	2011	doi:10.2903/j.efsa.2011.2091
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Ferric phosphate	233-149-7	10045-86-0	single chemical entity	Component is identical to the substance	Ferric phosphate	233-149-7	10045-86-0	iron(3+);phosphate	Not in list	FePO4	[O-]P(=O)([O-])[O-].[Fe+3]	InChI=1S/Fe.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3	inorganic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany - CoRMS: Poland	Ferric phosphate (Final addendum to Renewal Assessment Report)	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance ferric phosphate	29Jan2015	2015	doi:10.2903/j.efsa.2015.3973
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Ambiguous	small colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Ambiguous	small colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Ambiguous	large colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Ambiguous	large colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	4	Male	oral: unspecified	16.0000000000	h	yes	not applicable	Ambiguous			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male/Female	oral: gavage	16.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	mixture or formulation	Component is part of a mixture or forumlation	Sedaxane		874967-67-6	N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide	Not in list	C18H19F2N3O	FC(F)c4nn(C)cc4C(=O)Nc3ccccc3C2CC2C1CC1	InChI=1S/C18H19F2N3O/c1-23-9-14(16(22-23)17(19)20)18(24)21-15-5-3-2-4-11(15)13-8-12(13)10-6-7-10/h2-5,9-10,12-13,17H,6-8H2,1H3,(H,21,24)	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male/Female	oral: gavage	4.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	small colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid			3-(Difluoromethyl)-1H-pyrazole-4-carboxylic acid	Not in list	C5H4F2N2O2	FC(F)c1nncc1C(=O)O	InChI=1S/C5H4F2N2O2/c6-4(7)3-2(5(10)11)1-8-9-3/h1,4H,(H,8,9)(H,10,11)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	large colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	large colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	small colonies		RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Sedaxane		874967-67-6	single chemical entity	Component is a metabolite of the substance	3-(Difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid		176969-34-9	3-(Difluoromethyl)-1-methylpyrazole-4-carboxylic acid	Not in list	C6H6F2N2O2	CN1C=C(C(=N1)C(F)F)C(=O)O	InChI=1S/C6H6F2N2O2/c1-10-2-3(6(11)12)4(9-10)5(7)8/h2,5H,1H3,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: France	Sedaxane	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sedaxane	30Jan2013	2013	doi:10.2903/j.efsa.2013.3057
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)				Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)				Not reported			yes, concurrent vehicle	with	Positive			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: unspecified	48.0000000000		yes	not applicable	Negative		no evidence	RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: unspecified	12.0000000000		yes	not applicable	Negative		no evidence	RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: unspecified	72.0000000000		yes	not applicable	Negative		no evidence	RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Flutolanil		66332-96-5	single chemical entity	Component is identical to the substance	Flutolanil		66332-96-5	N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide	Flutolanil	C17H16F3NO2	CC(C)OC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2C(F)(F)F	InChI=1S/C17H16F3NO2/c1-11(2)23-13-7-5-6-12(10-13)21-16(22)14-8-3-4-9-15(14)17(18,19)20/h3-11H,1-2H3,(H,21,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	BDF1 mouse	12	Male/Female	oral: unspecified	24.0000000000		yes	not applicable	Negative		no evidence	RMS: Finland	Flutolanil	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance flutolanil	28Jul2008	2008	doi:10.2903/j.efsa.2008.126r
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is identical to the substance	Fluopyram		658066-35-4	N-[2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethyl]-2-(trifluoromethyl)benzamide	Fluopyram	C16H11ClF6N2O	C1=CC=C(C(=C1)C(=O)NCCC2=C(C=C(C=N2)C(F)(F)F)Cl)C(F)(F)F	InChI=1S/C16H11ClF6N2O/c17-12-7-9(15(18,19)20)8-25-13(12)5-6-24-14(26)10-3-1-2-4-11(10)16(21,22)23/h1-4,7-8H,5-6H2,(H,24,26)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-chloro-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C7H3ClF3NO2	Clc1cc(cnc1C(=O)O)C(F)(F)F	InChI=1/C7H3ClF3NO2/c8-4-1-3(7(9,10)11)2-12-5(4)6(13)14/h1-2H,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Fluopyram		658066-35-4	single chemical entity	Component is a metabolite of the substance	3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid			3-(methylsulfinyl)-5-(trifluoromethyl)-2-pyridinecarboxylic acid	Not in list	C8H6F3NO3S	O=C(O)c1ncc(cc1S(C)=O)C(F)(F)F	InChI=1/C8H6F3NO3S/c1-16(15)5-2-4(8(9,10)11)3-12-6(5)7(13)14/h2-3H,1H3,(H,13,14)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Germany	Fluopyram (Final addendum)	2012	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fluopyram	08Apr2013	2013	doi:10.2903/j.efsa.2013.3052
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hexythiazox (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hexythiazox (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hexythiazox (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hexythiazox (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hexythiazox (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hexythiazox (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hexythiazox (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hexythiazox (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hexythiazox (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is identical to the substance	Hexythiazox		78587-05-0	(4S,5S)-5-(4-chlorophenyl)-N-cyclohexyl-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Hexythiazox	C17H21ClN2O2S	C[C@H]2[C@@H](SC(=O)N2C(=O)NC1CCCCC1)c3ccc(Cl)cc3	InChI=1S/C17H21ClN2O2S/c1-11-15(12-7-9-13(18)10-8-12)23-17(22)20(11)16(21)19-14-5-3-2-4-6-14/h7-11,14-15H,2-6H2,1H3,(H,19,21)/t11-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hexythiazox (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-(cis-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@@H]1CC[C@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14+,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-4-methyl-2-oxo-N-(3-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	O=C1CC(CCC1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H19ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13,15H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			5-(4-chlorophenyl)-N-(3-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	OC1CCCC(C1)NC(=O)N3C(=O)SC(c2ccc(Cl)cc2)C3C	InChI=1/C17H21ClN2O3S/c1-10-15(11-5-7-12(18)8-6-11)24-17(23)20(10)16(22)19-13-3-2-4-14(21)9-13/h5-8,10,13-15,21H,2-4,9H2,1H3,(H,19,22)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one			(4S,5S)-5-(4-chlorophenyl)-4-methyl-1,3-thiazolidin-2-one	Not in list	C10H10ClNOS	C[C@@H]2NC(=O)S[C@H]2c1ccc(Cl)cc1	InChI=1/C10H10ClNOS/c1-6-9(14-10(13)12-6)7-2-4-8(11)5-3-7/h2-6,9H,1H3,(H,12,13)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-4-methyl-2-oxo-N-(4-oxocyclohexyl)-1,3-thiazolidine-3-carboxamide	Not in list	C17H19ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)NC1CCC(=O)CC1)c3ccc(Cl)cc3	InChI=1/C17H19ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13,15H,6-9H2,1H3,(H,19,22)/t10-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-N-[(1S,2S)-2-hydroxycyclohexyl]-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@H]2[C@@H](SC(=O)N2C(=O)N[C@H]1CCCC[C@@H]1O)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-6-8-12(18)9-7-11)24-17(23)20(10)16(22)19-13-4-2-3-5-14(13)21/h6-10,13-15,21H,2-5H2,1H3,(H,19,22)/t10-,13-,14-,15+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4R,5R)-5-(4-chlorophenyl)-N-(trans-4-hydroxycyclohexyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C17H21ClN2O3S	C[C@@H]2[C@H](SC(=O)N2C(=O)N[C@@H]1CC[C@@H](O)CC1)c3ccc(Cl)cc3	InChI=1/C17H21ClN2O3S/c1-10-15(11-2-4-12(18)5-3-11)24-17(23)20(10)16(22)19-13-6-8-14(21)9-7-13/h2-5,10,13-15,21H,6-9H2,1H3,(H,19,22)/t10-,13-,14-,15+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Hexythiazox		78587-05-0	single chemical entity	Component is a metabolite of the substance	(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide			(4S,5S)-5-(4-chlorophenyl)-4-methyl-2-oxo-1,3-thiazolidine-3-carboxamide	Not in list	C11H11ClN2O2S	C[C@H]1[C@@H](SC(=O)N1C(=O)N)c2ccc(Cl)cc2	InChI=1/C11H11ClN2O2S/c1-6-9(7-2-4-8(12)5-3-7)17-11(16)14(6)10(13)15/h2-6,9H,1H3,(H2,13,15)/t6-,9+/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Finland	Hexythiazox	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hexythiazox	14Oct2010	2010	doi:10.2903/j.efsa.2010.1722
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is identical to the substance	Fenbuconazole		114369-43-6	4-(4-chlorophenyl)-2-phenyl-2-(1H-1,2,4-triazol-1-ylmethyl)butanenitrile	Fenbuconazole	C19H17ClN4	ClC1=CC=C(CCC(C#N)(CN3N=CN=C3)C2=CC=CC=C2)C=C1	InChI=1S/C19H17ClN4/c20-18-8-6-16(7-9-18)10-11-19(12-21,13-24-15-22-14-23-24)17-4-2-1-3-5-17/h1-9,14-15H,10-11,13H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	fibroblast			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	kidney cells			Not reported			no data	without	Ambiguous			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	in vitro mammalian cell transformation assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Hamster (as animal)	kidney cells			Not reported			no data	with	Ambiguous			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: gavage	16.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	5	Male	intraperitoneal	48.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	5	Male	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	B6C3F1	5	Male	intraperitoneal	72.0000000000	h	no data	not applicable	Negative		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	no data	not applicable	Ambiguous		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	no data	not applicable	Ambiguous		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	no data	not applicable	Ambiguous		no evidence	RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5S)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19-/m0/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Fenbuconazole	601-308-3	114369-43-6	single chemical entity	Component is a metabolite of the substance	(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one			(3R,5R)-5-(4-chlorophenyl)-3-phenyl-3-(1H-1,2,4-triazol-1-ylmethyl)dihydrofuran-2(3H)-one	Not in list	C19H16ClN3O2	O=C2O[C@H](C[C@]2(Cn1ncnc1)c3ccccc3)c4ccc(Cl)cc4	InChI=1/C19H16ClN3O2/c20-16-8-6-14(7-9-16)17-10-19(18(24)25-17,11-23-13-21-12-22-23)15-4-2-1-3-5-15/h1-9,12-13,17H,10-11H2/t17-,19+/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Fenbuconazole	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenbuconazole	13Apr2010	2010	doi:10.2903/j.efsa.2010.1558
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is identical to the substance	Flupyrsulfuron-methyl-sodium		144740-54-5	sodium (4,6-dimethoxypyrimidin-2-yl)[({[3-(methoxycarbonyl)-6-(trifluoromethyl)pyridin-2-yl]sulfonyl}amino)carbonyl]azanide	Not in list	C15H13F3N5O7SNa	COC1=CC(=NC(=N1)[N-]C(=O)NS(=O)(=O)C2=C(C=CC(=N2)C(F)(F)F)C(=O)OC)OC.[Na+]	InChI=1S/C15H14F3N5O7S.Na/c1-28-9-6-10(29-2)21-13(20-9)22-14(25)23-31(26,27)11-7(12(24)30-3)4-5-8(19-11)15(16,17)18;/h4-6H,1-3H3,(H2,20,21,22,23,25);/q;+1/p-1	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Flupyrsulfuron-methyl (DPX-KE459)	1997	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4,6-dimethoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C14H10F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(OC)cc(OC)n3	InChI=1/C14H10F3N5O4/c1-25-8-5-9(26-2)20-12(19-8)22-10-6(11(23)21-13(22)24)3-4-7(18-10)14(15,16)17/h3-5H,1-2H3,(H,21,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione			1-(4-hydroxy-6-methoxypyrimidin-2-yl)-7-(trifluoromethyl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione	Not in list	C13H8F3N5O4	FC(F)(F)c1ccc2c(n1)N(C(=O)NC2=O)c3nc(O)cc(OC)n3	InChI=1/C13H8F3N5O4/c1-25-8-4-7(22)18-11(19-8)21-9-5(10(23)20-12(21)24)2-3-6(17-9)13(14,15)16/h2-4H,1H3,(H,18,19,22)(H,20,23,24)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	2-sulfamoyl-6-(trifluoromethyl)nicotinic acid			2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylic acid	Not in list	C7H5F3N2O4S	FC(F)(F)c1ccc(C(O)=O)c(n1)S(N)(=O)=O	InChI=1/C7H5F3N2O4S/c8-7(9,10)4-2-1-3(6(13)14)5(12-4)17(11,15)16/h1-2H,(H,13,14)(H2,11,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Positive			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Positive			RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Flupyrsulfuron-methyl-sodium		144740-54-5	single chemical entity	Component is a metabolite of the substance	methyl 2-sulfamoyl-6-(trifluoromethyl)nicotinate			methyl 2-sulfamoyl-6-(trifluoromethyl)pyridine-3-carboxylate	Not in list	C8H7F3N2O4S	FC(F)(F)c1ccc(C(=O)OC)c(n1)S(N)(=O)=O	InChI=1/C8H7F3N2O4S/c1-17-7(14)4-2-3-5(8(9,10)11)13-6(4)18(12,15)16/h2-3H,1H3,(H2,12,15,16)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France - CoRMS: Denmark	Flupyrsulfuron-methyl	2014	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flupyrsulfuron (variant evaluated flupyrsulfuron-methyl-sodium)	06Nov2014	2014	doi:10.2903/j.efsa.2014.3881
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is part of a group but not included in the group assessment	Thiophanate-methyl	245-740-7	23564-05-8	methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate	Thiophanate-methyl	C12H14N4O4S2	COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC	InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Carbendazim, Benomyl, Thiophanate-methyl (Addendum)	2002	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is part of a group but not included in the group assessment	Thiophanate-methyl	245-740-7	23564-05-8	methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate	Thiophanate-methyl	C12H14N4O4S2	COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC	InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: Germany	Carbendazim, Benomyl, Thiophanate-methyl (Addendum)	2002	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Carbendazim	234-232-0	10605-21-7	single chemical entity	Component is part of a group but not included in the group assessment	Thiophanate-methyl	245-740-7	23564-05-8	methyl N-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate	Thiophanate-methyl	C12H14N4O4S2	COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC	InChI=1S/C12H14N4O4S2/c1-19-11(17)15-9(21)13-7-5-3-4-6-8(7)14-10(22)16-12(18)20-2/h3-6H,1-2H3,(H2,13,15,17,21)(H2,14,16,18,22)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	not applicable	Positive			RMS: Germany	Carbendazim, Benomyl, Thiophanate-methyl (Addendum)	2002	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance carbendazim	12May2010	2010	doi:10.2903/j.efsa.2010.1598
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is identical to the substance	Tebufenozide		112410-23-8	N-tert-butyl-N'-(4-ethylbenzoyl)-3,5-dimethylbenzohydrazide	Tebufenozide	C22H28N2O2	O=C(N(C(C)(C)C)NC(C2=CC=C(CC)C=C2)=O)C1=CC(C)=CC(C)=C1	InChI=1S/C22H28N2O2/c1-7-17-8-10-18(11-9-17)20(25)23-24(22(4,5)6)21(26)19-13-15(2)12-16(3)14-19/h8-14H,7H2,1-6H3,(H,23,25)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: gavage	6.0000000000	h	yes	not applicable	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide			N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide	Not in list	C22H26N2O3	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C	InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide			N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide	Not in list	C22H26N2O3	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C	InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide			N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide	Not in list	C22H26N2O3	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C	InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide			N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide	Not in list	C22H26N2O3	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C	InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide			N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide	Not in list	C22H26N2O3	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C	InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide			N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide	Not in list	C22H26N2O3	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C	InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide			N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide	Not in list	C22H26N2O3	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C	InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide			N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide	Not in list	C22H26N2O3	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C	InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide			N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide	Not in list	C22H26N2O3	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C	InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide			N'-[(4-acetylphenyl)carbonyl]-N-tert-butyl-3,5-dimethylbenzohydrazide	Not in list	C22H26N2O3	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C	InChI=1/C22H26N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid			4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid	Not in list	C21H24N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C	InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent no treatment	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid			4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid	Not in list	C21H24N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C	InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent no treatment	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid			4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid	Not in list	C21H24N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C	InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent no treatment	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid			4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid	Not in list	C21H24N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C	InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent no treatment	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid			4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid	Not in list	C21H24N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C	InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent no treatment	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid			4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid	Not in list	C21H24N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C	InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent no treatment	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid			4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid	Not in list	C21H24N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C	InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent no treatment	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid			4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid	Not in list	C21H24N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C	InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent no treatment	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid			4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid	Not in list	C21H24N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C	InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent no treatment	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid			4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)benzoic acid	Not in list	C21H24N2O4	Cc1cc(cc(C)c1)C(=O)N(NC(=O)c2ccc(cc2)C(O)=O)C(C)(C)C	InChI=1/C21H24N2O4/c1-13-10-14(2)12-17(11-13)19(25)23(21(3,4)5)22-18(24)15-6-8-16(9-7-15)20(26)27/h6-12H,1-5H3,(H,22,24)(H,26,27)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent no treatment	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide	Not in list	C22H28N2O3	Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C	InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide	Not in list	C22H28N2O3	Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C	InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide	Not in list	C22H28N2O3	Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C	InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide	Not in list	C22H28N2O3	Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C	InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide	Not in list	C22H28N2O3	Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C	InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide	Not in list	C22H28N2O3	Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C	InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide	Not in list	C22H28N2O3	Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C	InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide	Not in list	C22H28N2O3	Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C	InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide	Not in list	C22H28N2O3	Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C	InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-(hydroxymethyl)-5-methylbenzohydrazide	Not in list	C22H28N2O3	Cc1cc(cc(CO)c1)C(=O)N(NC(=O)c2ccc(CC)cc2)C(C)(C)C	InChI=1/C22H28N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-13,25H,6,14H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3-(hydroxymethyl)-5-methylbenzohydrazide conjugates				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid			5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid	Not in list	C22H22N2O7	O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O	InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid			5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid	Not in list	C22H22N2O7	O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O	InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid			5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid	Not in list	C22H22N2O7	O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O	InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid			5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid	Not in list	C22H22N2O7	O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O	InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid			5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid	Not in list	C22H22N2O7	O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O	InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid			5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid	Not in list	C22H22N2O7	O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O	InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid			5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid	Not in list	C22H22N2O7	O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O	InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid			5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid	Not in list	C22H22N2O7	O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O	InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid			5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid	Not in list	C22H22N2O7	O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O	InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid			5-({2-[(4-acetylphenyl)carbonyl]-1-tert-butylhydrazinyl}carbonyl)benzene-1,3-dicarboxylic acid	Not in list	C22H22N2O7	O=C(O)c1cc(cc(c1)C(=O)N(NC(=O)c2ccc(cc2)C(C)=O)C(C)(C)C)C(O)=O	InChI=1/C22H22N2O7/c1-12(25)13-5-7-14(8-6-13)18(26)23-24(22(2,3)4)19(27)15-9-16(20(28)29)11-17(10-15)21(30)31/h5-11H,1-4H3,(H,23,26)(H,28,29)(H,30,31)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid			[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid	Not in list	C22H26N2O4	O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid			[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid	Not in list	C22H26N2O4	O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid			[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid	Not in list	C22H26N2O4	O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid			[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid	Not in list	C22H26N2O4	O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid			[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid	Not in list	C22H26N2O4	O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid			[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid	Not in list	C22H26N2O4	O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid			[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid	Not in list	C22H26N2O4	O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid			[4-({2-tert-butyl-2-[(3,5-dimethylphenyl)carbonyl]hydrazinyl}carbonyl)phenyl]acetic acid	Not in list	C22H26N2O4	O=C(O)Cc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H26N2O4/c1-14-10-15(2)12-18(11-14)21(28)24(22(3,4)5)23-20(27)17-8-6-16(7-9-17)13-19(25)26/h6-12H,13H2,1-5H3,(H,23,27)(H,25,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide			N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide	Not in list	C22H28N2O3	OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide			N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide	Not in list	C22H28N2O3	OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide			N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide	Not in list	C22H28N2O3	OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide			N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide	Not in list	C22H28N2O3	OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide			N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide	Not in list	C22H28N2O3	OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide			N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide	Not in list	C22H28N2O3	OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide			N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide	Not in list	C22H28N2O3	OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide			N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide	Not in list	C22H28N2O3	OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide			N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide	Not in list	C22H28N2O3	OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide			N-tert-butyl-N'-{[4-(1-hydroxyethyl)phenyl]carbonyl}-3,5-dimethylbenzohydrazide	Not in list	C22H28N2O3	OC(C)c1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C)c2)C(C)(C)C	InChI=1/C22H28N2O3/c1-14-11-15(2)13-19(12-14)21(27)24(22(4,5)6)23-20(26)18-9-7-17(8-10-18)16(3)25/h7-13,16,25H,1-6H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide	Not in list	C22H26N2O3	CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C	InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide	Not in list	C22H26N2O3	CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C	InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide	Not in list	C22H26N2O3	CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C	InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide	Not in list	C22H26N2O3	CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C	InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide	Not in list	C22H26N2O3	CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C	InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide	Not in list	C22H26N2O3	CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C	InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide	Not in list	C22H26N2O3	CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C	InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide	Not in list	C22H26N2O3	CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C	InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide	Not in list	C22H26N2O3	CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C	InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tebufenozide		112410-23-8	single chemical entity	Component is a metabolite of the substance	N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide			N-tert-butyl-N'-[(4-ethylphenyl)carbonyl]-3-formyl-5-methylbenzohydrazide	Not in list	C22H26N2O3	CCc1ccc(cc1)C(=O)NN(C(=O)c2cc(C)cc(C=O)c2)C(C)(C)C	InChI=1/C22H26N2O3/c1-6-16-7-9-18(10-8-16)20(26)23-24(22(3,4)5)21(27)19-12-15(2)11-17(13-19)14-25/h7-14H,6H2,1-5H3,(H,23,26)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tebufenozide	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tebufenozide	14Dec2010	2010	doi:10.2903/j.efsa.2010.1871
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Not reported		Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Not reported		Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Not reported		Male/Female	oral: gavage	12.0000000000	h	yes	not applicable	Negative			RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL		Male/Female	intraperitoneal	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL		Male/Female	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL		Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Ambiguous		no evidence	RMS: Germany	Tefluthrin	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Tefluthrin		79538-32-2	single chemical entity	Component is identical to the substance	Tefluthrin		79538-32-2	2,3,5,6-tetrafluoro-4-methylbenzyl 3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-en-1-yl]-2,2-dimethylcyclopropanecarboxylate	Tefluthrin	C17H14ClF7O2	O=C(OCC2=C(F)C(F)=C(C)C(F)=C2F)C1C(C)(C)C1/C=C(Cl)/C(F)(F)F	InChI=1S/C17H14ClF7O2/c1-6-11(19)13(21)7(14(22)12(6)20)5-27-15(26)10-8(16(10,2)3)4-9(18)17(23,24)25/h4,8,10H,5H2,1-3H3/b9-4-	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: Germany	Tefluthrin (Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance tefluthrin	09Dec2010	2010	doi:10.2903/j.efsa.2010.1709
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Inconclusive			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Inconclusive			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil (Final addendum)	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil (Final addendum)	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	14.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Fipronil (Final addendum)	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is identical to the substance	Fipronil		120068-37-3	5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethylsulfinyl) pyrazole-3-carbonitrile	Fipronil	C12H4Cl2F6N4OS	C1=C(C=C(C(=C1Cl)N2C(=C(C(=N2)C#N)S(=O)C(F)(F)F)N)Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)26(25)12(18,19)20/h1-2H,22H2	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	3	Male	oral: gavage	3.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: France	Fipronil (Final addendum)	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile			5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylthio-1-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(SC(F)(F)F)c1N)c(Cl)c2	InChI=1/C12H4Cl2F6N4S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)25-12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4O2S	FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4O2S	FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4O2S	FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4O2S	FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4O2S	FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4O2S	FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4O2S	FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4O2S	FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4O2S	FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylsulfonylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4O2S	FC(F)(F)S(=O)(=O)c1c(N)n(nc1C#N)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1S/C12H4Cl2F6N4O2S/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7(3-21)23-24)27(25,26)12(18,19)20/h1-2H,22H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	hepatocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-alpha,alpha,alpha-trifluoro-p-tolyl)-4-trifluoro-methylpyrazole-3-carbonitrile			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1H-pyrazole-3-carbonitrile	Not in list	C12H4Cl2F6N4	FC(F)(F)c1cc(Cl)c(c(Cl)c1)n2nc(C#N)c(c2N)C(F)(F)F	InChI=1S/C12H4Cl2F6N4/c13-5-1-4(11(15,16)17)2-6(14)9(5)24-10(22)8(12(18,19)20)7(3-21)23-24/h1-2H,22H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid, potassium salt			5-amino-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl) pyrazole-4-sulfonic acid	Not in list	C11H5Cl2F3N4O3S	FC(F)(F)c2cc(Cl)c(n1nc(C#N)c(c1N)S(O)(=O)=O)c(Cl)c2	InChI=1/C11H5Cl2F3N4O3S/c12-5-1-4(11(14,15)16)2-6(13)8(5)20-10(18)9(24(21,22)23)7(3-17)19-20/h1-2H,18H2,(H,21,22,23)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid	Not in list	C12H5Cl2F6N3O3S	FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O	InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid	Not in list	C12H5Cl2F6N3O3S	FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O	InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid	Not in list	C12H5Cl2F6N3O3S	FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O	InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid	Not in list	C12H5Cl2F6N3O3S	FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O	InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid	Not in list	C12H5Cl2F6N3O3S	FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O	InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid	Not in list	C12H5Cl2F6N3O3S	FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O	InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid	Not in list	C12H5Cl2F6N3O3S	FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O	InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid	Not in list	C12H5Cl2F6N3O3S	FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O	InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid	Not in list	C12H5Cl2F6N3O3S	FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O	InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-trifluoromethylsulfonylpyrazole-3-carboxylic acid			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfonyl]-1H-pyrazole-3-carboxylic acid	Not in list	C12H5Cl2F6N3O3S	FC(F)(F)S(=O)c2c(nn(c1c(Cl)cc(cc1Cl)C(F)(F)F)c2N)C(O)=O	InChI=1S/C12H5Cl2F6N3O4S/c13-4-1-3(11(15,16)17)2-5(14)7(4)23-9(21)8(6(22-23)10(24)25)28(26,27)12(18,19)20/h1-2H,21H2,(H,24,25)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Positive			RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	14	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Fipronil		120068-37-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-trifluoromethylsulfonyl-1H-pyrazole-3-carboxamide			5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(trifluoromethanesulfinyl)-1H-pyrazole-3-carboxamide	Not in list	C12H6Cl2F6N4O2S	FC(F)(F)S(=O)c1c(N)n(nc1C(N)=O)c2c(Cl)cc(cc2Cl)C(F)(F)F	InChI=1/C12H6Cl2F6N4O2S/c13-4-1-3(11(15,16)17)2-5(14)7(4)24-9(21)8(6(23-24)10(22)25)27(26)12(18,19)20/h1-2H,21H2,(H2,22,25)/t27?	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley	14	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: France	Fipronil	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment for bees for the active substance fipronil.	27May2013	2013	doi:10.2903/j.efsa.2013.3158
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	without	Positive			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes, concurrent vehicle	with	Positive			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	genome mutation	Drosophila SLRL test	in vivo	According to	OECD Guideline 477 (Genetic Toxicology: Sex-linked Recessive Lethal Test in Drosophila melanogaster)	No	Acceptable	Drosophila melanogaster (as animal)	Oregon-R	75	Male	oral: feed	3.0000000000	D	yes	not applicable	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	5	Male	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	ICR	5	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Not reported		No data	oral: unspecified	24.0000000000	h	yes	not applicable	Positive			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Hymexazol	233-000-6	10004-44-1	single chemical entity	Component is identical to the substance	Hymexazol	233-000-6	10004-44-1	5-methylisoxazol-3(2H)-one	Hymexazol	C4H5NO2	O=C1C=C(C)ON1	InChI=1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	Not reported		No data	oral: unspecified	48.0000000000	h	yes	not applicable	Positive			RMS: Finland	Hymexazol (Revised/Additional Report)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance hymexazol	13Aug2010	2010	doi:10.2903/j.efsa.2010.1653
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	no data	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	no data	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M17			Not reported			yes, concurrent vehicle	no data	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	no data	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	no information		RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	Equivalent or similar to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is identical to the substance	Triadimenol	259-537-6	55219-65-3	1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol	Triadimenol	C14H18ClN3O2	OC(C(C)(C)C)C(N2N=CN=C2)OC1=CC=C(Cl)C=C1	InChI=1S/C14H18ClN3O2/c1-14(2,3)12(19)13(18-9-16-8-17-18)20-11-6-4-10(15)5-7-11/h4-9,12-13,19H,1-3H3	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	NMRI	50	Male	oral: gavage	48.0000000000	D	no data	not applicable	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	1,2,4-Triazole	206-022-9	288-88-0	1H-1,2,4-triazole	Triazole, 1,2,4-	C2H3N3	C1=NC=NN1	InChI=1S/C2H3N3/c1-3-2-5-4-1/h1-2H,(H,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole acetic acid		28711-29-7	2-(1,2,4-Triazol-1-yl)acetic acid	Triazole acetic acid	C4H5N3O2	C1=NN(C=N1)CC(=O)O	InChI=1S/C4H5N3O2/c8-4(9)1-7-3-5-2-6-7/h2-3H,1H2,(H,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Hamster (as animal)	Chinese	16	Male/Female	oral: gavage	16.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CBA	5	Male	intraperitoneal	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CBA	5	Male	intraperitoneal	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CBA	5	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Triadimenol	259-537-6	55219-65-3	single chemical entity	Component is a metabolite of the substance	Triazole alanine	233-301-2	10109-05-4	2-amino-3-(1H-1,2,4-triazol-1-yl)propanoic acid	Triazole alanine	C5H8N4O2	C1=NNC(=N1)CC(C(=O)O)N	InChI=1S/C5H8N4O2/c6-3(5(10)11)1-4-7-2-8-9-4/h2-3H,1,6H2,(H,10,11)(H,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	NMRI	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Ambiguous		no evidence	RMS: The United Kingdom	Triadimenol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triadimenol	17Oct2008	2008	doi:10.2903/j.efsa.2008.177r
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	no information		RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	no information		RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Alderly Park Rat	5	Male	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	chromosome aberration	chromosome aberration assay	in vivo	Equivalent or similar to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	Alderly Park Rat	5	Male	oral: gavage	6.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: gavage	72.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	C57BL	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	12.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Sprague-Dawley	5	Male	oral: gavage	4.0000000000	h	yes	not applicable	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	chromosome aberration	dominant lethal assay	in vivo	Equivalent or similar to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	Yes	Acceptable	House mouse (as animal)	CD-1	15	Male	oral: gavage	7.0000000000	D	no data	not applicable	Negative			RMS: The United Kingdom	Flutriafol	2006	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	small colonies		RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Negative	large colonies		RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Flutriafol	616-367-0	76674-21-0	single chemical entity	Component is identical to the substance	Flutriafol	616-367-0	76674-21-0	1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol	Flutriafol	C16H13F2N3O	OC(CN1N=CN=C1)(C(C=C2)=CC=C2F)C(C=CC=C3)=C3F	InChI=1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: The United Kingdom	Flutriafol (Additional report)	2010	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance flutriafol	21Oct2010	2010	doi:10.2903/j.efsa.2010.1868
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity$indirect-toxicokinetic investigations	RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is identical to the substance	Fenpyrazamine		473798-59-3	S-allyl 5-amino-2,3-dihydro-2-isopropyl-3-oxo-4-(o-tolyl)pyrazole-1-carbothioate	Fenpyrazamine	C17H21N3O2S	n1(c(c(c(=O)n1C(C)C)c1ccccc1C)N)C(=O)SCC=C	InChI=1S/C17H21N3O2S/c1-5-10-23-17(22)20-15(18)14(16(21)19(20)11(2)3)13-9-7-6-8-12(13)4/h5-9,11H,1,10,18H2,2-4H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative		indirect evidence-systemic toxicity$indirect-toxicokinetic investigations	RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one			5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one	Not in list	C13H17N3O	O=C2C(c1ccccc1C)=C(N)NN2C(C)C	InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one			5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one	Not in list	C13H17N3O	O=C2C(c1ccccc1C)=C(N)NN2C(C)C	InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one			5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one	Not in list	C13H17N3O	O=C2C(c1ccccc1C)=C(N)NN2C(C)C	InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one			5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one	Not in list	C13H17N3O	O=C2C(c1ccccc1C)=C(N)NN2C(C)C	InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one			5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one	Not in list	C13H17N3O	O=C2C(c1ccccc1C)=C(N)NN2C(C)C	InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one			5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one	Not in list	C13H17N3O	O=C2C(c1ccccc1C)=C(N)NN2C(C)C	InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one			5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one	Not in list	C13H17N3O	O=C2C(c1ccccc1C)=C(N)NN2C(C)C	InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one			5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one	Not in list	C13H17N3O	O=C2C(c1ccccc1C)=C(N)NN2C(C)C	InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one			5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one	Not in list	C13H17N3O	O=C2C(c1ccccc1C)=C(N)NN2C(C)C	InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Fenpyrazamine		473798-59-3	single chemical entity	Component is a metabolite of the substance	5-Amino-1,2-dihydro-2-isopropyl-4-(otolyl) pyrazol-3-one			5-amino-4-(2-methylphenyl)-2-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one	Not in list	C13H17N3O	O=C2C(c1ccccc1C)=C(N)NN2C(C)C	InChI=1S/C13H17N3O/c1-8(2)16-13(17)11(12(14)15-16)10-7-5-4-6-9(10)3/h4-8,15H,14H2,1-3H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Austria	Fenpyrazamine (S-2188)	2011	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance fenpyrazamine	27Jan2012	2012	doi:10.2903/j.efsa.2012.2496
Haloxyfop-P		95977-29-0	single chemical entity	Component is identical to the substance	Haloxyfop-P		95977-29-0	(2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid	Haloxyfop-P	C15H11ClF3NO4	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is identical to the substance	Haloxyfop-P		95977-29-0	(2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid	Haloxyfop-P	C15H11ClF3NO4	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is identical to the substance	Haloxyfop-P		95977-29-0	(2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid	Haloxyfop-P	C15H11ClF3NO4	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is identical to the substance	Haloxyfop-P		95977-29-0	(2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid	Haloxyfop-P	C15H11ClF3NO4	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is identical to the substance	Haloxyfop-P		95977-29-0	(2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid	Haloxyfop-P	C15H11ClF3NO4	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is identical to the substance	Haloxyfop-P		95977-29-0	(2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid	Haloxyfop-P	C15H11ClF3NO4	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is identical to the substance	Haloxyfop-P		95977-29-0	(2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid	Haloxyfop-P	C15H11ClF3NO4	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is identical to the substance	Haloxyfop-P		95977-29-0	(2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid	Haloxyfop-P	C15H11ClF3NO4	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Ambiguous			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is identical to the substance	Haloxyfop-P		95977-29-0	(2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid	Haloxyfop-P	C15H11ClF3NO4	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1	organic	compound	Other	Other	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is identical to the substance	Haloxyfop-P		95977-29-0	(2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid	Haloxyfop-P	C15H11ClF3NO4	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is identical to the substance	Haloxyfop-P		95977-29-0	(2R)-2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenoxy)propanoic acid	Haloxyfop-P	C15H11ClF3NO4	O=C(O)[C@@H](C)Oc1ccc(cc1)Oc2ncc(cc2Cl)C(F)(F)F	InChI=1S/C15H11ClF3NO4/c1-8(14(21)22)23-10-2-4-11(5-3-10)24-13-12(16)6-9(7-20-13)15(17,18)19/h2-8H,1H3,(H,21,22)/t8-/m1/s1	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	without	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a group assessment	Haloxyfop-P-methyl ester	406-250-0	72619-32-0	Methyl 2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenoxy]propanoate	Not in list	C16H13ClF3NO4	CC(C(=O)OC)OC1=CC=C(C=C1)OC2=C(C=C(C=N2)C(F)(F)F)Cl	InChI=1S/C16H13ClF3NO4/c1-9(15(22)23-2)24-11-3-5-12(6-4-11)25-14-13(17)7-10(8-21-14)16(18,19)20/h3-9H,1-2H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	with	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: feed	42.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is part of a mixture or forumlation	Racemic Haloxyfop				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	Rat (as animal)	Sprague-Dawley	10	Male/Female	oral: feed	30.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Denmark	Haloxyfop-R	2004	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Positive			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Positive			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Positive			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone			3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone	Not in list	C7H5ClF3NO	ClC1=CC(=CN(C)C1=O)C(F)(F)F	InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone			3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone	Not in list	C7H5ClF3NO	ClC1=CC(=CN(C)C1=O)C(F)(F)F	InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone			3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone	Not in list	C7H5ClF3NO	ClC1=CC(=CN(C)C1=O)C(F)(F)F	InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone			3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone	Not in list	C7H5ClF3NO	ClC1=CC(=CN(C)C1=O)C(F)(F)F	InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone			3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone	Not in list	C7H5ClF3NO	ClC1=CC(=CN(C)C1=O)C(F)(F)F	InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone			3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone	Not in list	C7H5ClF3NO	ClC1=CC(=CN(C)C1=O)C(F)(F)F	InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone			3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone	Not in list	C7H5ClF3NO	ClC1=CC(=CN(C)C1=O)C(F)(F)F	InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone			3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone	Not in list	C7H5ClF3NO	ClC1=CC(=CN(C)C1=O)C(F)(F)F	InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone			3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone	Not in list	C7H5ClF3NO	ClC1=CC(=CN(C)C1=O)C(F)(F)F	InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone			3-chloro-1-methyl-5-(trifluoromethyl)-2(1H)-pyridinone	Not in list	C7H5ClF3NO	ClC1=CC(=CN(C)C1=O)C(F)(F)F	InChI=1/C7H5ClF3NO/c1-12-3-4(7(9,10)11)2-5(8)6(12)13/h2-3H,1H3	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344		Male/Female	oral: gavage	16.0000000000	h	yes	not applicable	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Fischer344		Male/Female	oral: gavage	4.0000000000	h	yes	not applicable	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	without	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Haloxyfop-P		95977-29-0	single chemical entity	Component is a metabolite of the substance	3-chloro-5-(trifluoromethyl)pyridin-2-ol		76041-71-9	3-chloro-5-(trifluoromethyl)-1H-pyridin-2-one	Not in list	C6H3ClF3NO	C1=C(C(=O)NC=C1C(F)(F)F)Cl	InChI=1S/C6H3ClF3NO/c7-4-1-3(6(8,9)10)2-11-5(4)12/h1-2H,(H,11,12)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Rat (as animal)	lymphocytes			Not reported			yes	with	Negative			RMS: Denmark	Haloxyfop-R (Addendum )	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance haloxyfop-P	12Dec2014	2014	doi:10.2903/j.efsa.2014.3931
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Positive			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Positive			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	72.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		direct evidence-cytotoxicity	RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	20	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	20	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	ICR	5	Male	oral: unspecified	48.0000000000	h	no data	not applicable	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is identical to the substance	Triflusulfuron-methyl		126535-15-7	Methyl 2-[[4-(dimethylamino)-6-(2,2,2-trifluoroethoxy)-1,3, 5-triazin-2-yl]carbamoylsulfamoyl]-3-methylbenzoate	Triflusulfuron-Methyl	C17H19F3N6O6S	CC1=CC=CC(=C1S(=O)(=O)NC(=O)NC2=NC(=NC(=N2)OCC(F)(F)F)N(C)C)C(=O)OC	InChI=1S/C17H19F3N6O6S/c1-9-6-5-7-10(12(27)31-4)11(9)33(29,30)25-15(28)22-13-21-14(26(2)3)24-16(23-13)32-8-17(18,19)20/h5-7H,8H2,1-4H3,(H2,21,22,23,24,25,28)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	According to	OECD Guideline 483 (Mammalian Spermatogonial Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	ICR	5	Male	oral: unspecified	24.0000000000	h	no data	not applicable	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	415-500-8	145963-84-4	2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C7H10F3N5O	CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	415-500-8	145963-84-4	2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C7H10F3N5O	CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	415-500-8	145963-84-4	2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C7H10F3N5O	CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	415-500-8	145963-84-4	2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C7H10F3N5O	CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	415-500-8	145963-84-4	2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C7H10F3N5O	CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	415-500-8	145963-84-4	2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C7H10F3N5O	CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	415-500-8	145963-84-4	2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C7H10F3N5O	CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N,N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	415-500-8	145963-84-4	2-N,2-N-dimethyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C7H10F3N5O	CN(C)C1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C7H10F3N5O/c1-15(2)5-12-4(11)13-6(14-5)16-3-7(8,9)10/h3H2,1-2H3,(H2,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine			2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C6H8F3N5O	CNC1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine			2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C6H8F3N5O	CNC1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine			2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C6H8F3N5O	CNC1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine			2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C6H8F3N5O	CNC1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine			2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C6H8F3N5O	CNC1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine			2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C6H8F3N5O	CNC1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine			2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C6H8F3N5O	CNC1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine			2-N-methyl-6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C6H8F3N5O	CNC1=NC(=NC(=N1)N)OCC(F)(F)F	InChI=1S/C6H8F3N5O/c1-11-4-12-3(10)13-5(14-4)15-2-6(7,8)9/h2H2,1H3,(H3,10,11,12,13,14)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	6-(2,2,2-Trifluoroethoxy)-1,3,5-triazine-2,4-diamine			6-(2,2,2-trifluoroethoxy)-1,3,5-triazine-2,4-diamine	Not in list	C5H6F3N5O	FC(F)(F)COc1nc(N)nc(N)n1	InChI=1/C5H6F3N5O/c6-5(7,8)1-14-4-12-2(9)11-3(10)13-4/h1H2,(H4,9,10,11,12,13)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	without	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	Hamster (as animal)	CHO			Not reported			yes	with	Negative			RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Triflusulfuron-methyl		126535-15-7	single chemical entity	Component is a metabolite of the substance	7-Methyl-1,2-benzisothiazol-3(2H)-one 1,1-dioxide			7-methyl-1,2-benzothiazol-3(2H)-one 1,1-dioxide	Not in list	C8H7NO3S	Cc1cccc2c1S(=O)(=O)NC2=O	InChI=1S/C8H7NO3S/c1-5-3-2-4-6-7(5)13(11,12)9-8(6)10/h2-4H,1H3,(H,9,10)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: France	Triflusulfuron-methyl	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance triflusulfuron (considered variant triflusulfuron-methyl).	17Apr2009	2009	doi:10.2903/j.efsa.2009.195r
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			no data	with	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	large colonies		RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	small colonies		RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	large colonies		RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	small colonies		RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	Equivalent or similar to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Yes	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Inconclusive		no evidence	RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	oral: unspecified	48.0000000000	h	no data	not applicable	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	oral: unspecified	24.0000000000	h	no data	not applicable	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		No data	oral: unspecified	72.0000000000	h	no data	not applicable	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley		No data	intraperitoneal	12.0000000000	h	no data	not applicable	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Sprague-Dawley		No data	intraperitoneal	6.0000000000	h	no data	not applicable	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	Rat (as animal)	Wistar	30	Male	oral: gavage	1.0000000000	week	yes, concurrent vehicle	not applicable	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	CD-1		Male	oral: unspecified	8.0000000000	week	no data	not applicable	Negative			RMS: Germany	Glyphosate	1998	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	small colonies		RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	small colonies		RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	large colonies		RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	Equivalent or similar to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	Yes	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	large colonies		RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	Equivalent or similar to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	Yes	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	77	Male	intraperitoneal	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	7	Male	intraperitoneal	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	intraperitoneal	24.0000000000	h	yes	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male	oral: unspecified	24.0000000000	h	yes	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI	12	Male	oral: unspecified	48.0000000000	h	yes	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: unspecified	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	Rat (as animal)	Crj:CD(SD)	10	Male/Female	oral: unspecified	48.0000000000	h	yes, concurrent vehicle	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	no information		RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	no information		RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	NMRI		Male/Female	oral: unspecified	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is a metabolite of the substance	(aminomethyl)phosphonic acid	623-325-5	1066-51-9	aminomethylphosphonic acid	Not in list	CH6NO3P	C(N)P(=O)(O)O	InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Rodeo)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Rodeo)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Rodeo)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Rodeo)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Rodeo)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Rodeo)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Rodeo)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Rodeo)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 2139)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 2139)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 2139)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 2139)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 2139)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 2139)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 2139)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 2139)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 14445t)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 14445t)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 14445t)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 14445t)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 14445t)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 14445t)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 14445t)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 14445t)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Glifos)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Glifos)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Glifos)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Glifos)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Glifos)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Glifos)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Glifos)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Glifos)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Rodeo)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	48.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Rodeo)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	72.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Rodeo)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	72.0000000000	h	no data	not applicable	Negative		direct evidence-cytotoxicity	RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	48.0000000000	h	no data	not applicable	Negative		direct evidence-cytotoxicity	RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		direct evidence-cytotoxicity	RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 14445t)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	72.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 14445t)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (MON 14445t)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	48.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Glifos)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss		Male/Female	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		no evidence	RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 8080				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 8080				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 8080				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 8080				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 8080				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 8080				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 8080				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 8080				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 0818				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 0818				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 0818				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 0818				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 0818				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 0818				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 0818				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 0818				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Dodigen 4022				Not in list				organic	no structure			chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 0818				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	MON 0818				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	CD-1		Male/Female	intraperitoneal	48.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Negative		direct evidence-cytotoxicity	RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	48.0000000000	h	no data	not applicable	Negative		direct evidence-cytotoxicity	RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Glyphosate isopropyl amine salt	254-056-8	38641-94-0	N-(phosphonomethyl)glycine - isopropylamine (1:1)	Not in list	C6H17N2O5P	CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-]	InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Glyphosate isopropyl amine salt	254-056-8	38641-94-0	N-(phosphonomethyl)glycine - isopropylamine (1:1)	Not in list	C6H17N2O5P	CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-]	InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	48.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	4.0000000000	h	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	4.0000000000	h	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	6.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	4.0000000000	h	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	6.0000000000	h	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	4.0000000000	h	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	hepatocytes			intraperitoneal			no data	not applicable	Ambiguous			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Glyphosate isopropyl amine salt	254-056-8	38641-94-0	N-(phosphonomethyl)glycine - isopropylamine (1:1)	Not in list	C6H17N2O5P	CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-]	InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	kidney cells			intraperitoneal			no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Glyphosate isopropyl amine salt	254-056-8	38641-94-0	N-(phosphonomethyl)glycine - isopropylamine (1:1)	Not in list	C6H17N2O5P	CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-]	InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	hepatocytes			intraperitoneal			no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			DNA damage and/or repair	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	kidney cells			intraperitoneal			no data	not applicable	Ambiguous			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vivo	Equivalent or similar to	OECD Guideline 489	No data	Acceptable	Other	Not reported		No data	Not reported	24.0000000000	h	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	dominant lethal assay	in vivo	No guideline available	Not reported	Not applicable	Acceptable	Drosophila melanogaster (as animal)	Not reported		Male	oral: feed			no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			no data	no data	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			no data	no data	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	no data	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	72.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Percozyd 10 SL)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	no data	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	48.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	24.0000000000	h	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Percozyd 10 SL)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	no data	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Percozyd 10 SL)				Not in list				organic	no structure			gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	no data	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Drosophila melanogaster (as animal)	Not reported			Not reported			no data	no data	Inconclusive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Glyphosate isopropyl amine salt	254-056-8	38641-94-0	N-(phosphonomethyl)glycine - isopropylamine (1:1)	Not in list	C6H17N2O5P	CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-]	InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			no data	without	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Glyphosate isopropyl amine salt	254-056-8	38641-94-0	N-(phosphonomethyl)glycine - isopropylamine (1:1)	Not in list	C6H17N2O5P	CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-]	InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			no data	with	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Glyphosate isopropyl amine salt	254-056-8	38641-94-0	N-(phosphonomethyl)glycine - isopropylamine (1:1)	Not in list	C6H17N2O5P	CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-]	InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Glyphosate isopropyl amine salt	254-056-8	38641-94-0	N-(phosphonomethyl)glycine - isopropylamine (1:1)	Not in list	C6H17N2O5P	CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-]	InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			no data	without	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Herbazed)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	1.0000000000	D	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Herbazed)				Not in list				organic	no structure			chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	spleen cells			Not reported			no data	without	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Herbazed)				Not in list				organic	no structure			DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	House mouse (as animal)	spleen cells			Not reported			no data	without	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Herbazed)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	oral: unspecified	21.0000000000	D	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Herbazed)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	oral: unspecified	14.0000000000	D	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Herbazed)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	oral: unspecified	7.0000000000	D	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Herbazed)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	oral: unspecified	1.0000000000	D	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Herbazed)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	3.0000000000	D	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Herbazed)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal	5.0000000000	D	no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Glyphosate isopropyl amine salt	254-056-8	38641-94-0	N-(phosphonomethyl)glycine - isopropylamine (1:1)	Not in list	C6H17N2O5P	CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-]	InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			no	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Glyphosate isopropyl amine salt	254-056-8	38641-94-0	N-(phosphonomethyl)glycine - isopropylamine (1:1)	Not in list	C6H17N2O5P	CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-]	InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is part of a group assessment	Glyphosate isopropyl amine salt	254-056-8	38641-94-0	N-(phosphonomethyl)glycine - isopropylamine (1:1)	Not in list	C6H17N2O5P	CC(C)[NH3+].CC(C)[NH3+].CC(C)[NH3+].C(C(=O)[O-])NCP(=O)([O-])[O-]	InChI=1S/C3H8NO5P.3C3H9N/c5-3(6)1-4-2-10(7,8)9;3*1-3(2)4/h4H,1-2H2,(H,5,6)(H2,7,8,9);3*3H,4H2,1-2H3	organic	compound	Other	Other	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Bovinae (bovines = Tribe bovini) (as animal)	lymphocytes			Not reported			no data	no data	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	single cell gel/comet assay in mammalian cells for detection of DNA damage	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Human (as organism)	Not reported			Not reported			no data	without	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal			no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian cell micronucleus test	in vitro	According to	OECD Guideline 487 (In Vitro Mammalian Cell Micronucleus Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal			no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal			no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	Rabbit (as animal)	Not reported		No data	oral: feed	60.0000000000	D	no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	oral: unspecified			no data	not applicable	Negative			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is the active ingredient of the mixture or formulation	Glyphosate formulation (Roundup)				Not in list				organic	no structure			chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	Not reported		No data	intraperitoneal			no data	not applicable	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Glyphosate	213-997-4	1071-83-6	single chemical entity	Component is identical to the substance	Glyphosate	213-997-4	1071-83-6	2-(phosphonomethylamino)acetic acid	Glyphosate	C3H8NO5P	C(C(=O)O)NCP(=O)(O)O	InChI=1S/C3H8NO5P/c5-3(6)1-4-2-10(7,8)9/h4H,1-2H2,(H,5,6)(H2,7,8,9)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	sister chromatid exchange assay in mammalian cells	in vitro	According to	OECD Guideline 479 (Genetic Toxicology: In Vitro Sister Chromatid Exchange Assay in Mammalian Cells)	No	Acceptable	Human (as organism)	fibroblast			Not reported			no data	without	Positive			RMS: Germany - CoRMS: Slovakia	Glyphosate (Renewal Assessment Report)	2013	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance glyphosate	30Oct2015	2015	doi:10.2903/j.efsa.2015.4302
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	12.0000000000	h	yes	not applicable	Negative			RMS: Finland	Tolylfluanid (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	48.0000000000	h	yes	not applicable	Negative			RMS: Finland	Tolylfluanid (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Tolylfluanid	211-986-9	731-27-1	single chemical entity	Component is identical to the substance	Tolylfluanid	211-986-9	731-27-1	N-[dichloro(fluoro)methyl]sulfanyl-N-(dimethylsulfamoyl)-4-methylaniline	Tolylfluanid	C10H13Cl2FN2O2S2	CC1=CC=C(C=C1)N(SC(F)(Cl)Cl)S(=O)(=O)N(C)C	InChI=1S/C10H13Cl2FN2O2S2/c1-8-4-6-9(7-5-8)15(18-10(11,12)13)19(16,17)14(2)3/h4-7H,1-3H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	NMRI	5	Male	intraperitoneal	24.0000000000	h	yes	not applicable	Negative			RMS: Finland	Tolylfluanid (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tolylfluanid	21Apr2005	2005	doi:10.2903/j.efsa.2005.29r
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 97			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	Not reported			Not reported			no data	no data	Positive			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	yeast cytogenetic assay	in vitro	According to	OECD Guideline 480 (Genetic Toxicology: Saccharomyces cerevisiae, Gene Mutation Assay)	No	Acceptable	Aspergillus nidulans (as organism)	Not reported			Not reported			no data	no data	Positive			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	Not reported			Not reported			no data	no data	Positive			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	embryo cells			Not reported			no data	without	Positive			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	M45			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	without	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	Bacillus subtilis recombination assay	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Bacillus subtilis (as organism)	H17			Not reported			yes, concurrent vehicle	with	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	Not applicable	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	no data	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	chromosome aberration assay	in vivo	According to	OECD Guideline 475 (Mammalian Bone Marrow Chromosome Aberration Test)	No	Acceptable	House mouse (as animal)	CD-1		Male	oral: gavage	24.0000000000	h	no data	not applicable	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	other	in vivo	No guideline available	Not reported	Not applicable	Acceptable	House mouse (as animal)	ICR		No data	intraperitoneal	3.0000000000	h	no data	not applicable	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	C3H	15	Male	oral: unspecified	6.0000000000	week	no data	not applicable	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Thiabendazole	205-725-8	148-79-8	single chemical entity	Component is identical to the substance	Thiabendazole	205-725-8	148-79-8	2-(thiazol-4-yl)benzimidazole	Thiabendazole	C10H7N3S	C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3	InChI=1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	dominant lethal assay	in vivo	According to	OECD Guideline 478 (Genetic Toxicology: Rodent Dominant Lethal Test)	No	Acceptable	House mouse (as animal)	CD-1		No data	oral: gavage	8.0000000000	week	no data	not applicable	Negative			RMS: Spain	Thiabendazole	1996	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole	04Nov2014	2014	doi:10.2903/j.efsa.2014.3880
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	No guideline followed	Not reported	No	Acceptable	Rat (as animal)	Sprague-Dawley	30	Male/Female	oral: gavage	12.0000000000	h	yes	not applicable	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	No guideline followed	Not reported	No	Acceptable	Rat (as animal)	Sprague-Dawley	30	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	mammalian germ cell cytogenetic assay	in vivo	No guideline followed	Not reported	No	Acceptable	Rat (as animal)	Sprague-Dawley	30	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	mixture or formulation	Component is identical to the substance	Flurtamone	619-224-0	96525-23-4	(RS)-5-methylamino-2-phenyl-4-(α,α,α-trifluoro-m-tolyl)furan-3(2H)-one	Flurtamone	C18H14F3NO2	CNC1=C(C(=O)C(O1)C2=CC=CC=C2)C3=CC(=CC=C3)C(F)(F)F	InChI=1S/C18H14F3NO2/c1-22-17-14(12-8-5-9-13(10-12)18(19,20)21)15(23)16(24-17)11-6-3-2-4-7-11/h2-10,16,22H,1H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	Equivalent or similar to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	Yes	Acceptable	House mouse (as animal)	Not reported	12	Male/Female	oral: unspecified	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	with	Negative	no information		RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes, concurrent vehicle	without	Negative	no information		RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	Trifluoroacetic acid	200-929-3	76-05-1	2,2,2-trifluoroacetic acid	Not in list	C2HF3O2	C(=O)(C(F)(F)F)O	InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			yes, concurrent vehicle	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			yes, concurrent vehicle	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	without	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			yes	with	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	small colonies		RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	small colonies		RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	without	Negative	large colonies		RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			yes	with	Positive	large colonies		RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	6	Male	oral: gavage	24.0000000000	h	yes, concurrent vehicle	not applicable	Negative		no evidence	RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: gavage	12.0000000000	h	yes	not applicable	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Flurtamone	619-224-0	96525-23-4	single chemical entity	Component is a metabolite of the substance	3-(trifluoromethyl)benzoic acid	207-230-2	454-92-2	3-(trifluoromethyl)benzoic acid	Not in list	C8H5F3O2	FC(F)(F)c1cccc(c1)C(=O)O	InChI=1S/C8H5F3O2/c9-8(10,11)6-3-1-2-5(4-6)7(12)13/h1-4H,(H,12,13)	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	unscheduled DNA synthesis	in vivo	According to	OECD Guideline 486 (Unscheduled DNA Synthesis (UDS) Test with Mammalian Liver Cells in vivo)	No	Acceptable	Rat (as animal)	Wistar	4	Male	oral: gavage	2.0000000000	h	yes	not applicable	Negative			RMS: Czech Republic - CoRMS: Ireland	Flurtamone Active substance data	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance flurtamone	06Jun2016	2016	doi: 10.2903/j.efsa.2016.4498
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	with	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	with	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1538			Not reported			no data	without	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	without	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	with	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 98			Not reported			no data	with	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	with	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 100			Not reported			no data	without	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1537			Not reported			no data	without	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	gene mutation	bacterial reverse mutation assay	in vitro	Equivalent or similar to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	Yes	Acceptable	Salmonella typhimurium (as organism)	TA 1535			Not reported			no data	without	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			no data	with	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			no data	with	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	(k12)p3478			Not reported			no data	without	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	other	in vitro	No guideline available	Not reported	Not applicable	Acceptable	Escherichia coli (as organism)	W3110			Not reported			no data	without	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	No guideline followed	Not reported	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	According to	OECD Guideline 481 (Genetic Toxicology: Saccharomyces cerevisiae, Mitotic Recombination Assay)	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	genome mutation	mitotic recombination in Saccharomyces cerevisiae	in vitro	No guideline followed	Not reported	No	Acceptable	Saccharomyces cerevisiae (as organism)	D7			Not reported			no data	without	Positive			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	DNA damage and/or repair	DNA damage and repair assay, unscheduled DNA synthesis in mammalian cells in vitro	in vitro	According to	OECD Guideline 482 (Genetic Toxicology: DNA Damage and Repair, Unscheduled DNA Synthesis in Mammalian Cells In Vitro)	No	Acceptable	Rat (as animal)	hepatocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	without	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Thiodicarb	261-848-7	59669-26-0	single chemical entity	Component is identical to the substance	Thiodicarb	261-848-7	59669-26-0	Methyl N-[methyl-[methyl-(1-methylsulfanylethylideneamino)oxycarbonylamino] sulfanylcarbamoyl]oxyethanimidothioate	Thiodicarb	C10H18N4O4S3	CC(=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC)SC	InChI=1S/C10H18N4O4S3/c1-7(19-5)11-17-9(15)13(3)21-14(4)10(16)18-12-8(2)20-6/h1-6H3	organic	compound	PubChem canonical SMILES	PubChem InChI	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			no data	with	Negative			RMS: The United Kingdom	Thiodicarb (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance thiodicarb	30Jan2006	2006	doi:10.2903/j.efsa.2006.55r
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	TA 102			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	without	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Sintofen (aka cintofen)		130561-48-7	single chemical entity	Component is identical to the substance	Sintofen (aka cintofen)		130561-48-7	1-(4-Chlorophenyl)-5-(2-methoxyethoxy)-4-oxo-1,4-dihydro-3-cinnolinecarboxylic acid	Sintofen (aka cintofen)	C18H15ClN2O5	O=C(O)C2=NN(c1ccc(Cl)cc1)c3cccc(OCCOC)c3C2=O	InChI=1S/C18H15ClN2O5/c1-25-9-10-26-14-4-2-3-13-15(14)17(22)16(18(23)24)20-21(13)12-7-5-11(19)6-8-12/h2-8H,9-10H2,1H3,(H,23,24)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	WP2 uvr A pKM 101			Not reported			yes, concurrent vehicle	with	Negative			RMS: France	Sintofen (revised DAR)	2009	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance sintofen	14Dec2010	2010	doi:10.2903/j.efsa.2010.1931
Tralkoxydim		87820-88-0	single chemical entity	Component is a metabolite of the substance	3-(2,4,6-trimethylphenyl)pentanedioic acid			3-(2,4,6-trimethylphenyl)pentanedioic acid	Not in list	C14H18O4	OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C	InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is a metabolite of the substance	3-(2,4,6-trimethylphenyl)pentanedioic acid			3-(2,4,6-trimethylphenyl)pentanedioic acid	Not in list	C14H18O4	OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C	InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	with	Negative			RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is a metabolite of the substance	3-(2,4,6-trimethylphenyl)pentanedioic acid			3-(2,4,6-trimethylphenyl)pentanedioic acid	Not in list	C14H18O4	OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C	InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Escherichia coli (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is a metabolite of the substance	3-(2,4,6-trimethylphenyl)pentanedioic acid			3-(2,4,6-trimethylphenyl)pentanedioic acid	Not in list	C14H18O4	OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C	InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18)	organic	compound	Other	Other	gene mutation	bacterial reverse mutation assay	in vitro	According to	OECD Guideline 471 (Bacterial Reverse Mutation Assay)	No	Acceptable	Salmonella typhimurium (as organism)	Not reported			Not reported			no data	without	Negative			RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is a metabolite of the substance	3-(2,4,6-trimethylphenyl)pentanedioic acid			3-(2,4,6-trimethylphenyl)pentanedioic acid	Not in list	C14H18O4	OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C	InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	large colonies		RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is a metabolite of the substance	3-(2,4,6-trimethylphenyl)pentanedioic acid			3-(2,4,6-trimethylphenyl)pentanedioic acid	Not in list	C14H18O4	OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C	InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	large colonies		RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is a metabolite of the substance	3-(2,4,6-trimethylphenyl)pentanedioic acid			3-(2,4,6-trimethylphenyl)pentanedioic acid	Not in list	C14H18O4	OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C	InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	without	Negative	small colonies		RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is a metabolite of the substance	3-(2,4,6-trimethylphenyl)pentanedioic acid			3-(2,4,6-trimethylphenyl)pentanedioic acid	Not in list	C14H18O4	OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C	InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	House mouse (as animal)	lymphoma L5178Y cells			Not reported			no data	with	Negative	small colonies		RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is a metabolite of the substance	3-(2,4,6-trimethylphenyl)pentanedioic acid			3-(2,4,6-trimethylphenyl)pentanedioic acid	Not in list	C14H18O4	OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C	InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	without	Negative			RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Tralkoxydim		87820-88-0	single chemical entity	Component is a metabolite of the substance	3-(2,4,6-trimethylphenyl)pentanedioic acid			3-(2,4,6-trimethylphenyl)pentanedioic acid	Not in list	C14H18O4	OC(=O)CC(CC(O)=O)c1c(C)cc(C)cc1C	InChI=1/C14H18O4/c1-8-4-9(2)14(10(3)5-8)11(6-12(15)16)7-13(17)18/h4-5,11H,6-7H2,1-3H3,(H,15,16)(H,17,18)	organic	compound	Other	Other	chromosome aberration	in vitro mammalian chromosome aberration test	in vitro	According to	OECD Guideline 473 (In vitro Mammalian Chromosome Aberration Test)	No	Acceptable	Human (as organism)	lymphocytes			Not reported			no data	with	Negative			RMS: The United Kingdom	Tralkoxydim (Addendum 1)	2007	Conclusion on Pesticides Peer Review	EFSA	Conclusion regarding the peer review of the pesticide risk assessment of the active substance tralkoxydim	28Jul2008	2008	doi:10.2903/j.efsa.2008.139r
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	with	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Fenamidone	605-252-0	161326-34-7	single chemical entity	Component is a metabolite of the substance	(5S)-5-methyl-2-(methylthio)-5-phenyl-3,5-dihydro- 4H-imidazol-4-one			(5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3,5-dihydro-4H-imidazol-4-one	Not in list	C11H12N2OS	C[C@]1(N=C(SC)NC1=O)c2ccccc2	InChI=1/C11H12N2OS/c1-11(8-6-4-3-5-7-8)9(14)12-10(13-11)15-2/h3-7H,1-2H3,(H,12,13,14)/t11-/m0/s1	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	lung fibroblasts (V79)			Not reported			yes	without	Negative			RMS: Czech republic - CoRMS: France	Fenamidone (Renewal Assessment Report)	2016	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance fenamidone	22Feb2016	2016	doi:10.2903/j.efsa.2016.4406
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Greece	Trifluralin (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Trifluralin	216-428-8	1582-09-8	single chemical entity	Component is identical to the substance	Trifluralin	216-428-8	1582-09-8	2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline	Trifluralin	C13H16F3N3O4	CCCN(CCC)c1c(cc(cc1[N+](=O)[O-])C(F)(F)F)[N+](=O)[O-]	InChI=1/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	CD-1	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: Greece	Trifluralin (Final addendum)	2005	Conclusion on Pesticides Peer Review	EFSA	Peer review of the pesticide risk assessment of the active substance trifluralin	05Aug2009	2009	doi:10.2903/j.efsa.2009.327r
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	with	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	gene mutation	mammalian cell gene mutation assay	in vitro	According to	OECD Guideline 476 (In vitro Mammalian Cell Gene Mutation Test)	No	Acceptable	Hamster (as animal)	CHO			Not reported			yes, concurrent vehicle	without	Negative			RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	24.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	48.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201
Thifensulfuron-methyl	616-673-4	79277-27-3	single chemical entity	Component is a metabolite of the substance	methyl 3-sulfamoylthiophene-2-carboxylate			methyl 3-sulfamoylthiophene-2-carboxylate	Not in list	C6H7NO4S2	O=S(N)(=O)c1ccsc1C(=O)OC	InChI=1/C6H7NO4S2/c1-11-6(8)5-4(2-3-12-5)13(7,9)10/h2-3H,1H3,(H2,7,9,10)	organic	compound	Other	Other	chromosome aberration	Mammalian erythrocyte micronucleus test	in vivo	According to	OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)	No	Acceptable	House mouse (as animal)	Swiss	10	Male/Female	oral: gavage	72.0000000000	h	yes	not applicable	Negative		no evidence	RMS: The United Kingdom	Thifensulfuron-methyl	2015	Conclusion on Pesticides Peer Review	EFSA	Conclusion on the peer review of the pesticide risk assessment of the active substance thifensulfuron-methyl	23Jul2015	2015	doi:10.2903/j.efsa.2015.4201